SEdb 2.0
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Gene overview

Strategies/Algorithm: lasso Ensembl ID: ENSG00000265972
Gene: TXNIP Gene type: protein_coding
Strand: - External links:
Genomic region: chr1:145992435-145996579 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_098700134 chr1:145968565-146008065 Sample_02_0987 Blood K562_Control_1 134 17 210 81 1 192 1037 TXNIP,POLR3GL,RBM8A,LIX1L,LOC101928979,GNRHR2,ANKRD34A,RNVU1-6,PEX11B,HFE2
SE_02_152900633 chr1:145974806-146008126 Sample_02_1529 Peripheral blood neutrophils_0BC75 633 10 173 71 1 190 1025 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2
SE_02_066000535 chr1:145975269-146007941 Sample_02_0660 Mammary gland MCF10DCIS 535 12 169 69 1 175 930 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2,PEX11B,RNF115
SE_00_005500044 chr1:145977139-146010763 Sample_00_0055 Spleen spleen 34y 44 18 175 74 1 168 827 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2,PEX11B,PDE4DIP,ITGA10
SE_01_010400043 chr1:145977186-146012449 Sample_01_0104 Lung upper lobe of left lung 43 9 184 78 1 168 817 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2,PEX11B,ITGA10,PIAS3,POLR3C
SE_02_153200236 chr1:145977202-146007839 Sample_02_1532 Mammary gland MCF10A 236 6 163 68 1 168 817 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2,PEX11B,RNF115
SE_02_092700208 chr1:145977273-146007719 Sample_02_0927 Peripheral blood neutrophils_US 208 12 163 68 1 168 800 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2
SE_02_120301115 chr1:145977289-146008293 Sample_02_1203 Brain NB1 1115 10 164 68 1 168 799 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2,ANKRD35
SE_02_090200052 chr1:145977307-146019894 Sample_02_0902 Heart left ventricle_LV1558 52 9 216 90 2 221 1188 TXNIP,HFE2,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A
SE_02_092800245 chr1:145977314-146007585 Sample_02_0928 Peripheral blood neutrophils_Ecoli 245 6 163 68 1 168 798 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2
SE_02_059600446 chr1:145977368-146007420 Sample_02_0596 Mammary gland MCF10A_ DMSO 446 9 161 67 1 168 792 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2,PEX11B,RNF115
SE_02_113200892 chr1:145977387-146015690 Sample_02_1132 Pancreas KLM1 wt 892 10 199 83 1 172 785 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2,PEX11B,ITGA10,PIAS3,RNF115,ANKRD35
SE_02_066100204 chr1:145977392-146010296 Sample_02_0661 Mammary gland MCF10DCIS-TetTCF7 204 14 171 73 1 168 784 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2,PEX11B,RNF115
SE_02_072500278 chr1:145977405-146006952 Sample_02_0725 Mammary gland MCF10A-YAP5SA_ctrl 278 14 156 66 1 166 780 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2,PEX11B,RNF115
SE_00_004600188 chr1:145977427-146010832 Sample_00_0046 Heart right ventricle_34y 188 21 173 74 1 168 772 TXNIP,POLR3GL,RBM8A,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2,NUDT17,PEX11B,ITGA10,PIAS3
SE_02_153000696 chr1:145977538-146007532 Sample_02_1530 Peripheral blood neutrophils_0BA0X 696 6 161 68 1 167 753 TXNIP,POLR3GL,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,HFE2,RBM8A
SE_02_153100358 chr1:145977615-146007454 Sample_02_1531 Peripheral blood neutrophils_0B9ZK 358 9 158 67 1 167 742 TXNIP,POLR3GL,LOC101928979,LIX1L,RNVU1-6,HFE2,ANKRD34A,RBM8A
SE_02_084100180 chr1:145977652-146050161 Sample_02_0841 Blood THP-1_untr 180 21 410 186 4 248 1629 TXNIP,HFE2,POLR3GL,LOC101928979,LIX1L,RNVU1-6,ANKRD34A,PEX11B,ITGA10,RBM8A,PIAS3
SE_01_010500187 chr1:145977702-146011103 Sample_01_0105 Thyroid gland thyroid gland_54y 187 15 172 74 1 167 727 TXNIP,POLR3GL,LOC101928979,LIX1L,RNVU1-6,HFE2,ANKRD34A,ITGA10,RBM8A,ANKRD35
SE_02_151300296 chr1:145977714-146011162 Sample_02_1513 Lung Transitional AT2->1 cells 296 8 172 74 1 167 726 TXNIP,POLR3GL,LOC101928979,LIX1L,RNVU1-6,HFE2,ANKRD34A,PEX11B,ITGA10,RBM8A,PIAS3,POLR3C
SE_02_060200209 chr1:145977717-146007883 Sample_02_0602 Mammary gland MCF10A_p63shRNA_DMSO 209 7 158 68 1 167 726 TXNIP,POLR3GL,LOC101928979,LIX1L,RNVU1-6,HFE2,ANKRD34A,PEX11B,RBM8A,RNF115
SE_02_060300197 chr1:145977719-146007930 Sample_02_0603 Mammary gland MCF10A_p63shRNA_Nutlin3A 197 8 158 68 1 167 726 TXNIP,POLR3GL,LOC101928979,LIX1L,RNVU1-6,HFE2,ANKRD34A,PEX11B,RBM8A,RNF115
SE_00_004900316 chr1:145977720-146000174 Sample_00_0049 Small intestine small intestine 30y 316 11 121 52 0 162 726 TXNIP,POLR3GL,ANKRD34A,HFE2,LIX1L,ITGA10,RBM8A
SE_02_151200103 chr1:145977766-146011005 Sample_02_1512 Lung Purified AT2 cells 103 8 170 74 1 167 722 TXNIP,POLR3GL,LOC101928979,LIX1L,RNVU1-6,HFE2,ANKRD34A,PEX11B,ITGA10,RBM8A,PIAS3,POLR3C
SE_02_153300096 chr1:145977771-146011006 Sample_02_1533 Lung purified primary alveolar epithelial type 2 cells 96 9 170 74 1 167 719 TXNIP,POLR3GL,LOC101928979,LIX1L,RNVU1-6,HFE2,ANKRD34A,PEX11B,ITGA10,RBM8A,PIAS3,POLR3C
SE_00_005700342 chr1:145977844-146000326 Sample_00_0057 Heart right ventricle 3y 342 21 122 52 0 159 704 TXNIP,POLR3GL,ANKRD34A,HFE2,LIX1L,NUDT17,PEX11B,ITGA10,PIAS3
SE_02_059300320 chr1:145977862-146000481 Sample_02_0593 Fetal spleenocytes fetal naive T cells 320 9 123 52 0 159 704 TXNIP,POLR3GL,ANKRD34A,HFE2,LIX1L,PEX11B,PDE4DIP,ITGA10,RBM8A
SE_02_060000470 chr1:145977890-146007408 Sample_02_0600 Mammary gland MCF10A_p53shRNA_DMSO 470 8 156 67 1 164 698 TXNIP,POLR3GL,LOC101928979,LIX1L,RNVU1-6,HFE2,ANKRD34A,PEX11B,RBM8A,RNF115
SE_02_103300729 chr1:146024515-146049256 Sample_02_1033 Haematopoietic and lymphoid tissue bone marrow K562 729 4 160 81 2 0 248 RNVU1-6,HFE2,LOC101928979,TXNIP,POLR3GL,LIX1L,ANKRD34A
SE_04_000100941 chr1:146067406-146139772 Sample_04_0001 Blood heat shocked K562 941 18 94 21 0 0 5082 NBPF10,RNVU1-6,HFE2,LOC101928979,TXNIP,POLR3GL
Genomic distribution of SEs associated with TXNIP
Genome Browser

The strength of the tissue affected by the gene

Expression of TXNIP

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)