SEdb 2.0
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Gene overview

Strategies/Algorithm: lasso Ensembl ID: ENSG00000136244
Gene: IL6 Gene type: protein_coding
Strand: + External links:
Genomic region: chr7:22725884-22732002 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_095001043 chr7:22481266-22511589 Sample_02_0950 Umbilical vein HUVEC_WT 1043 10 961 121 0 17 229 STEAP1B,IL6
SE_02_049900766 chr7:22560146-22613348 Sample_02_0499 Fetal lung IMR90 IR Senescence 766 22 1337 49 5 85 491 LOC100506178,STEAP1B,IL6
SE_02_094900069 chr7:22560214-22611496 Sample_02_0949 Umbilical artery HUAEC_WT 69 27 1288 48 5 85 491 LOC100506178,IL6,STEAP1B,TOMM7
SE_02_049800095 chr7:22560527-22611828 Sample_02_0498 Fetal lung IMR90 Senescent_1 95 22 1292 48 5 85 491 LOC100506178,STEAP1B,IL6
SE_02_062000216 chr7:22564963-22602097 Sample_02_0620 Aortic Aortic Endothelial Cells_DF 216 14 924 34 3 71 393 LOC100506178,IL6,STEAP1B
SE_02_122900136 chr7:22646404-22724668 Sample_02_1229 Haematopoietic and lymphoid tissue bone marrow K562_Control 136 42 2337 192 13 133 0 LOC401312,LOC541472,IL6,TOMM7
SE_04_000100639 chr7:22662375-22684573 Sample_04_0001 Blood heat shocked K562 639 1 605 53 5 20 0 LOC401312,LOC541472,IL6
SE_02_109900096 chr7:22662449-22723668 Sample_02_1099 Haematopoietic and lymphoid tissue bone marrow K562_DMSO_noIFNG 96 28 1837 179 12 101 0 LOC401312,LOC541472,IL6,TOMM7
SE_02_113000082 chr7:22664279-22725268 Sample_02_1130 Haematopoietic and lymphoid tissue bone marrow K562_??Np63?? expressing 82 17 1834 181 11 95 7 LOC401312,LOC541472,IL6,TOMM7
SE_02_111600227 chr7:22666275-22725735 Sample_02_1116 Haematopoietic and lymphoid tissue bone marrow K562_native 227 14 1795 178 10 97 55 LOC541472,LOC401312,IL6,TOMM7
SE_02_098700106 chr7:22666692-22718480 Sample_02_0987 Blood K562_Control_1 106 15 1567 159 9 67 0 LOC541472,LOC401312,IL6,TOMM7
SE_02_054600042 chr7:22666706-22710085 Sample_02_0546 Bone marrow K562_MYO1D Non-hub KO 42 9 1291 124 6 29 0 LOC541472,LOC401312,IL6,TOMM7
SE_02_098800154 chr7:22666818-22718904 Sample_02_0988 Blood K562_EPZ 154 12 1574 158 9 67 0 LOC541472,LOC401312,IL6,TOMM7
SE_02_054700363 chr7:22667366-22683331 Sample_02_0547 Bone marrow K562_MYO1D_Hub_KO 363 5 437 43 2 7 0 LOC541472,LOC401312,IL6
SE_02_142200361 chr7:22669808-22682439 Sample_02_1422 Haematopoietic and lymphoid tissue bone marrow K562_Triptolide_0h 361 6 340 35 0 5 0 LOC541472,LOC401312,IL6
SE_02_142300033 chr7:22675866-22717970 Sample_02_1423 Haematopoietic and lymphoid tissue bone marrow K562_Triptolide_1h 33 14 1321 129 4 58 0 LOC541472,LOC401312,IL6,TOMM7
SE_02_103300065 chr7:22694301-22711182 Sample_02_1033 Haematopoietic and lymphoid tissue bone marrow K562 65 1 574 57 0 9 0 LOC541472,LOC401312,IL6,TOMM7
SE_02_101700959 chr7:22695332-22721387 Sample_02_1017 Embryo H9_Mesendoderm 24h_Hydroxyurea 959 5 870 95 3 52 0 LOC541472,LOC401312,IL6
SE_02_101600507 chr7:22696545-22722062 Sample_02_1016 Embryo H9_Mesendoderm_24h 507 7 844 94 3 54 0 LOC541472,LOC401312,IL6
SE_04_000200372 chr7:22699983-22710598 Sample_04_0002 Blood cold shocked K562 372 1 381 43 0 0 0 LOC541472,LOC401312,IL6,TOMM7
SE_02_054500260 chr7:22700092-22710565 Sample_02_0545 Bone marrow K562 WT 260 1 375 43 0 0 0 LOC541472,LOC401312,IL6,TOMM7
Genomic distribution of SEs associated with IL6
Genome Browser

The strength of the tissue affected by the gene

Expression of IL6

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)