SEdb 2.0
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  2. Super-enhancer search result of gene-based

Gene overview

Strategies/Algorithm: closest_active Ensembl ID: ENSG00000115904
Gene: SOS1 Gene type: protein_coding
Strand: - External links:
Genomic region: chr2:38981549-39124345 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_103600287 chr2:39052903-39145768 Sample_02_1036 Mammary gland HCC70_XY018 287 29 2727 175 5 127 398 SOS1
SE_02_130200192 chr2:39058150-39151337 Sample_02_1302 Lymphoma RL DMSO 192 39 2737 179 7 97 347 SOS1
SE_02_122400185 chr2:39059717-39150642 Sample_02_1224 Bone marrow normal plasma cell 185 47 2692 175 7 90 313 SOS1
SE_02_104900600 chr2:39060543-39157027 Sample_02_1049 Peripheral blood CD4+ cell_ROMI 600 48 2876 176 7 91 313 SOS1
SE_02_023200648 chr2:39083697-39136520 Sample_02_0232 Tonsil ILC3 648 10 1627 103 2 63 260 SOS1
SE_02_082600938 chr2:39090409-39129608 Sample_02_0826 Stomach gastric tumor 938 12 1247 90 1 61 260 SOS1
SE_02_101701833 chr2:39090719-39125378 Sample_02_1017 Embryo H9_Mesendoderm 24h_Hydroxyurea 1833 5 1127 84 1 59 260 SOS1
SE_02_115300391 chr2:39090934-39151186 Sample_02_1153 Lymphoma RL_R1446C_gRNA1 391 16 1809 122 4 76 260 SOS1
SE_02_045600046 chr2:39092195-39161142 Sample_02_0456 Th17 lymphocytes Th17-IL-10- Day 0 46 18 2058 131 5 78 260 SOS1
SE_02_045700097 chr2:39092408-39145017 Sample_02_0457 Th17 lymphocytes Th17-IL-10- Day 5 97 15 1563 103 2 66 260 SOS1
SE_02_032000744 chr2:39092436-39130138 Sample_02_0320 Peripheral blood MO1043_ICN1_HA_H3K27Ac_a 744 6 1171 86 1 61 260 SOS1
SE_02_021300653 chr2:39092859-39144287 Sample_02_0213 Burkitts lymphoma of the left maxilla Raji_JQ1 653 8 1534 101 2 66 260 SOS1
SE_02_045400042 chr2:39092862-39158404 Sample_02_0454 Th17 lymphocytes Th17-IL-10+ Day 0 42 13 1957 124 5 78 260 SOS1
SE_02_023100389 chr2:39093166-39137336 Sample_02_0231 Tonsil ILC1 389 8 1345 92 2 66 260 SOS1
SE_02_045500175 chr2:39093536-39144564 Sample_02_0455 Th17 lymphocytes Th17-IL-10+ Day 5 175 12 1524 100 2 66 260 SOS1
SE_02_103500402 chr2:39094359-39157826 Sample_02_1035 Mammary gland HCC70_Vehicle 402 21 1901 118 4 78 260 SOS1
SE_02_104301214 chr2:39094427-39151284 Sample_02_1043 Peripheral blood Peripheral blood cells_CTCL1200 1214 20 1690 113 4 76 260 SOS1
SE_02_156000938 chr2:39094771-39128690 Sample_02_1560 Gastrointestinal Stromal GIST-9_PDGFRA e18 938 7 1075 77 1 61 260 SOS1
SE_02_130300280 chr2:39094839-39151812 Sample_02_1303 Lymphoma RL_tazemetostat 280 25 1697 112 4 76 260 SOS1
SE_02_115200259 chr2:39095036-39158520 Sample_02_1152 Lymphoma RL_WT_gRNA1 259 16 1902 118 5 78 260 SOS1
SE_02_115500235 chr2:39095099-39158611 Sample_02_1155 Lymphoma RL_R1446C_gRNA1_KDAC005 235 15 1903 118 5 78 260 SOS1
SE_02_130400347 chr2:39095169-39151935 Sample_02_1304 Lymphoma RL_lenalidomide_tazemetostat 347 23 1694 111 4 76 260 SOS1
SE_02_106000132 chr2:39095347-39143615 Sample_02_1060 Bone TC71_SA2 KO 132 12 1450 94 2 66 260 SOS1
SE_02_121800429 chr2:39095938-39143218 Sample_02_1218 Bone marrow Daudi 429 16 1423 93 2 66 260 SOS1
SE_02_030101037 chr2:39096795-39129962 Sample_02_0301 Neuroblastoma GIMEN 1037 5 1052 75 1 61 260 SOS1
SE_02_068700941 chr2:39099566-39125378 Sample_02_0687 Lung NCI-H146_no infection 941 6 852 60 1 59 260 SOS1
SE_02_106500323 chr2:39099720-39143924 Sample_02_1065 Lymphoma KARPAS-422_DMSO_8d 323 18 1325 80 2 66 260 SOS1
SE_02_046500061 chr2:39105627-39164523 Sample_02_0465 Adipose subcutaneous adipocytes 61 31 1757 100 4 78 260 SOS1
SE_02_077502118 chr2:39106397-39149305 Sample_02_0775 Pancreas EndoC-BH1_SE 2118 7 1244 78 2 66 260 SOS1
SE_02_108301150 chr2:39106960-39125481 Sample_02_1083 Macula macula 1150 3 596 40 0 59 260 SOS1
SE_02_003900710 chr2:39107020-39125595 Sample_02_0039 Embryo AFG 710 3 595 40 0 60 260 SOS1
SE_02_004000799 chr2:39107060-39125635 Sample_02_0040 Embryo PFG 799 3 594 40 0 59 260 SOS1
SE_02_058400623 chr2:39107091-39125143 Sample_02_0584 Lung H1299 WT 623 4 581 39 0 55 260 SOS1
SE_02_074500280 chr2:39108099-39125359 Sample_02_0745 Embryo ES derived cardiac progenitor cells_day7 280 3 547 34 0 52 260 SOS1
SE_02_122900219 chr2:39113857-39172869 Sample_02_1229 Haematopoietic and lymphoid tissue bone marrow K562_Control 219 30 1740 86 4 72 260 SOS1,CDKL4
SE_02_104701919 chr2:39114457-39156837 Sample_02_1047 Peripheral blood CD4+ cells_CTCL1181 1919 16 1217 60 3 69 260 SOS1
SE_02_109500032 chr2:39114567-39157103 Sample_02_1095 Blood CD34 Erythroid cells_Don002 32 10 1228 62 3 69 260 SOS1
SE_04_000100676 chr2:39114662-39157029 Sample_04_0001 Blood heat shocked K562 676 6 1219 61 3 69 260 SOS1
SE_02_146800638 chr2:39114832-39125367 Sample_02_1468 Blood HUDEP-2_WT 638 2 336 19 0 52 260 SOS1
SE_02_034300422 chr2:39115437-39151971 Sample_02_0343 Bone marrow HSPC_A0 422 8 1021 57 3 69 260 SOS1
SE_02_109600094 chr2:39115438-39157234 Sample_02_1096 Blood CD34 Erythroid cells_Don003 94 11 1194 61 3 69 260 SOS1
SE_02_058000492 chr2:39116704-39157806 Sample_02_0580 Blood HEL_sgSIK3e4 492 10 1163 59 3 69 260 SOS1
SE_02_022200189 chr2:39116843-39151833 Sample_02_0222 Blood DU-528 189 4 966 55 3 67 260 SOS1
SE_02_043100264 chr2:39117032-39157275 Sample_02_0431 Peripheral blood CD34+HSPC-derived-erythroid-precursors 264 9 1138 59 3 67 260 SOS1
SE_02_103300313 chr2:39117210-39156772 Sample_02_1033 Haematopoietic and lymphoid tissue bone marrow K562 313 7 1114 56 3 67 260 SOS1
SE_02_001600346 chr2:39117301-39152897 Sample_02_0016 Blood erythroblasts 346 5 988 55 3 67 260 SOS1
SE_02_083400556 chr2:39117473-39157784 Sample_02_0834 Bone marrow TEX-HIST1H3F-WT-Rx_cells 556 10 1133 58 3 69 260 SOS1
SE_02_083300481 chr2:39117572-39150575 Sample_02_0833 Bone marrow TEX-HIST1H3F-K27I-2-Rx_cells 481 8 907 53 3 66 260 SOS1
SE_02_057900554 chr2:39117607-39157816 Sample_02_0579 Blood HEL_sgNeg2 554 11 1128 58 3 69 260 SOS1
SE_02_057600580 chr2:39117621-39157818 Sample_02_0576 Blood HEL_sgLKB1e2 580 8 1127 58 3 68 260 SOS1
SE_02_134600199 chr2:39117626-39129460 Sample_02_1346 Leukophereses leukophereses_p400 199 4 328 20 0 51 260 SOS1
SE_02_083600641 chr2:39117768-39136313 Sample_02_0836 Bone marrow TEX-HIST1H3H-WT-Rx_cells 641 5 500 26 1 53 260 SOS1
SE_02_058200505 chr2:39117889-39144313 Sample_02_0582 Blood MOLM13_SIK3TQ_HG 505 7 711 37 1 55 260 SOS1
SE_02_083700677 chr2:39117991-39143937 Sample_02_0837 Bone marrow TEX-Luciferase-Rx_cells 677 7 694 36 1 55 260 SOS1
SE_02_061700953 chr2:39118073-39125511 Sample_02_0617 HSPC FL CD34+CD38-/lowCD90+ HSPC 953 1 218 15 0 50 260 SOS1
SE_02_075100228 chr2:39118113-39150297 Sample_02_0751 Lymphoma Rec-1_WO 228 16 879 52 3 55 260 SOS1
SE_02_155400952 chr2:39118196-39128380 Sample_02_1554 Gastrointestinal Stromal GIST-3_KIT e11 952 5 283 18 0 50 260 SOS1
SE_02_057700582 chr2:39118241-39143974 Sample_02_0577 Blood MOLM13_empty 582 7 690 36 1 55 260 SOS1
SE_02_075000178 chr2:39118290-39150198 Sample_02_0750 Lymphoma Rec-1_GSI 178 15 871 52 3 55 260 SOS1
SE_01_001200584 chr2:39118340-39125895 Sample_01_0012 Lung A549_dexamethasone_1h 584 2 217 15 0 49 260 SOS1
SE_01_003700463 chr2:39118350-39125688 Sample_01_0037 Liver hepatocyte 463 1 214 15 0 49 260 SOS1
SE_02_122300980 chr2:39118468-39140572 Sample_02_1223 Bone marrow KMS28BM 980 8 601 33 1 54 260 SOS1
SE_02_083500712 chr2:39118532-39157821 Sample_02_0835 Bone marrow TEX-HIST1H3H-K27M-Rx_cells 712 9 1097 57 3 66 260 SOS1
SE_02_028400439 chr2:39118535-39144108 Sample_02_0284 Pelvis patient 119 439 5 685 36 1 54 260 SOS1
SE_02_012400255 chr2:39118618-39144002 Sample_02_0124 Embryo Embryonic-stem-cells_Naive 255 2 681 35 1 54 260 SOS1
SE_00_004300734 chr2:39118647-39125518 Sample_00_0043 Stomach stomach_96d 734 1 203 14 0 49 260 SOS1
SE_02_099400410 chr2:39118660-39147434 Sample_02_0994 Blood MOLM13_SIK3TQ 410 12 765 42 2 54 260 SOS1
SE_02_081900795 chr2:39118676-39125317 Sample_02_0819 Ovary Mucinous ovarian cancer 795 3 196 13 0 47 260 SOS1
SE_00_002000679 chr2:39118688-39141324 Sample_00_0020 Large intestine large-intestine_108d 679 3 614 33 1 54 260 SOS1
SE_02_081700146 chr2:39118690-39142018 Sample_02_0817 Ovary Epithelial ovarian cancer 146 6 629 33 1 54 260 SOS1
SE_00_003600663 chr2:39118710-39125816 Sample_00_0036 Small intestine small-intestine_108days 663 1 206 14 0 49 260 SOS1
SE_02_066900834 chr2:39118747-39125339 Sample_02_0669 Prostate prostate cancer_DSG 834 2 194 11 0 47 260 SOS1
SE_02_054500209 chr2:39118765-39157848 Sample_02_0545 Bone marrow K562 WT 209 8 1095 55 3 66 260 SOS1
SE_02_062300492 chr2:39118805-39125583 Sample_02_0623 Mammary gland TAMR_E2 492 2 203 12 0 49 260 SOS1
SE_02_092101130 chr2:39118885-39125312 Sample_02_0921 Heart embryonic heart_CS22 1130 3 192 11 0 47 260 SOS1
SE_02_155200482 chr2:39118959-39164628 Sample_02_1552 HMSCs hMSC ATCC SCRC-4000 482 13 1307 67 4 66 260 SOS1
SE_02_074600493 chr2:39119081-39125327 Sample_02_0746 Embryo ES derived primitive cardiomyocite_day15 493 1 183 11 0 47 260 SOS1
SE_01_010400928 chr2:39119204-39129048 Sample_01_0104 Lung upper lobe of left lung 928 4 270 15 0 49 260 SOS1
SE_02_049300295 chr2:39119231-39125577 Sample_02_0493 Islets differentiated hESCs Early pancreatic progenitor cells 295 2 186 11 0 49 260 SOS1
SE_02_049400309 chr2:39119239-39125388 Sample_02_0494 Islets differentiated hESCs Late pancreatic progenitor cells 309 4 179 10 0 47 260 SOS1
SE_01_007900825 chr2:39119265-39130136 Sample_01_0079 Peyers patch Peyers-patch 825 2 293 17 0 49 260 SOS1
SE_01_010701246 chr2:39119272-39129334 Sample_01_0107 Esophagus esophagus squamous epithelium 1246 4 274 15 0 49 260 SOS1
SE_02_049500284 chr2:39119360-39125496 Sample_02_0495 Islets differentiated hESCs Early LSD1 inhibition PP2 284 4 183 11 0 46 260 SOS1
SE_01_008400989 chr2:39119367-39130522 Sample_01_0084 Spleen spleen 989 3 301 17 0 47 260 SOS1
SE_02_036500148 chr2:39119436-39125617 Sample_02_0365 Skeletal muscle NCI0075 148 1 184 11 0 47 260 SOS1
SE_01_009900825 chr2:39119486-39125171 Sample_01_0099 Colon transverse colon 825 2 170 10 0 44 260 SOS1
SE_02_033000721 chr2:39119505-39125451 Sample_02_0330 Endoderm MHG 721 2 178 10 0 45 260 SOS1
SE_02_027400843 chr2:39119506-39125406 Sample_02_0274 Endometriosis hTERT_KD 843 2 176 10 0 45 260 SOS1
SE_00_004101009 chr2:39119512-39125543 Sample_00_0041 Stomach stomach_3y 1009 3 181 11 0 47 260 SOS1
SE_02_004900271 chr2:39119518-39125881 Sample_02_0049 Embryo endodermal CyT49_GTtoH 271 2 185 11 0 47 260 SOS1
SE_02_093001510 chr2:39119594-39145058 Sample_02_0930 Mid-gestation placenta trophoblast__SynT 1510 12 680 34 1 52 260 SOS1
SE_02_074700403 chr2:39119608-39143576 Sample_02_0747 Embryo ES derived ventricular cardiomyocyte_day80 403 9 637 32 1 52 260 SOS1
SE_00_004200704 chr2:39119614-39125351 Sample_00_0042 Stomach stomach_30y 704 2 168 10 0 45 260 SOS1
SE_02_109900332 chr2:39119627-39156704 Sample_02_1099 Haematopoietic and lymphoid tissue bone marrow K562_DMSO_noIFNG 332 12 1032 50 3 62 260 SOS1
SE_02_004800357 chr2:39119646-39125559 Sample_02_0048 Embryo endodermal CyT49_HE 357 2 176 11 0 47 260 SOS1
SE_02_052500463 chr2:39119662-39125208 Sample_02_0525 Pancreas iPS derived pancreatic precursor cells_Lane1 463 4 163 10 0 45 260 SOS1
SE_02_004500295 chr2:39119700-39125420 Sample_02_0045 Embryo endodermal CyT49_ES_D7 295 2 167 10 0 45 260 SOS1
SE_02_052400505 chr2:39119720-39125402 Sample_02_0524 Pancreas iPS derived pancreatic precursor cells_Lane2 505 2 167 9 0 45 260 SOS1
SE_00_004900779 chr2:39119734-39129868 Sample_00_0049 Small intestine small intestine 30y 779 4 272 15 0 47 260 SOS1
SE_00_005800496 chr2:39119900-39125159 Sample_00_0058 Stomach stomach 34y 496 3 155 9 0 42 260 SOS1
SE_02_004600394 chr2:39120725-39125364 Sample_02_0046 Embryo endodermal CyT49_ES_D10 394 3 130 9 0 23 108 SOS1
SE_02_004400354 chr2:39120747-39125383 Sample_02_0044 Embryo endodermal CyT49_ES_D5 354 2 130 9 0 23 108 SOS1
SE_02_046600676 chr2:39122378-39164990 Sample_02_0466 Adipose visceral adipocytes 676 26 1219 62 4 33 108 SOS1
SE_02_106100587 chr2:39122865-39143565 Sample_02_1061 Bone TC71_WT 587 8 545 26 1 21 108 SOS1
SE_02_148800588 chr2:39122865-39143565 Sample_02_1488 Bone TC-71 588 8 545 26 1 21 108 SOS1
SE_02_059000617 chr2:39122971-39142666 Sample_02_0590 Cervix HeLa Kyoto_Luci PWWP2A siRNA 617 10 521 25 1 21 108 SOS1
SE_02_058800637 chr2:39123116-39142554 Sample_02_0588 Cervix HeLa Kyoto_untreated 637 6 512 25 1 20 108 SOS1
SE_02_024400260 chr2:39123373-39161821 Sample_02_0244 Foreskin foreskin_D11 260 7 1073 53 4 32 108 SOS1
SE_02_139300701 chr2:39123472-39143448 Sample_02_1393 Lymph node anaplastic large cell lymphoma cells_ALK+#54 701 6 522 24 1 20 108 SOS1
SE_02_157301147 chr2:39123552-39161690 Sample_02_1573 Endothelial Undifferentiated Pleomorphic Sarcoma 1147 7 1063 53 4 32 108 SOS1
SE_02_148100761 chr2:39123587-39157058 Sample_02_1481 Bone MIC 761 13 932 44 3 30 108 SOS1
SE_02_009300408 chr2:39123722-39161226 Sample_02_0093 Umbilical cord umbilical-cord-derived-mesenchymal-stem-cells_Control_cycle_6 408 6 1044 51 4 32 108 SOS1
SE_02_006100101 chr2:39123852-39140890 Sample_02_0061 Adipose hMADS-3_white 101 3 449 20 1 20 108 SOS1
SE_02_068500642 chr2:39138666-39142988 Sample_02_0685 Lung NCI-H1048_no infection 642 1 106 5 0 0 0 SOS1
SE_02_054700476 chr2:39139650-39151064 Sample_02_0547 Bone marrow K562_MYO1D_Hub_KO 476 7 308 20 2 10 0 SOS1
Genomic distribution of SEs associated with SOS1
Genome Browser

The strength of the tissue affected by the gene

Expression of SOS1

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)