SEdb 2.0
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Gene overview

Strategies/Algorithm: closest_active Ensembl ID: ENSG00000177700
Gene: POLR2L Gene type: protein_coding
Strand: - External links:
Genomic region: chr11:837356-842529 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_144500468 chr11:831160-848084 Sample_02_1445 Adipose SW872_TAZ4SA 468 1 656 91 3 92 2119 TSPAN4,CD151,POLR2L,CRACR2B,SNORA52,PIDD1,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_042700506 chr11:831370-845630 Sample_02_0427 Colon HCT116_shPAF1 506 1 588 85 3 86 1961 TSPAN4,CD151,POLR2L,EFCAB4A,SNORA52,LRDD,PNPLA2,SLC25A22,CEND1,RPLP2
SE_02_029400718 chr11:831376-847589 Sample_02_0294 Pancreatic L3-6_DMSO 718 1 637 90 3 90 2074 TSPAN4,CD151,POLR2L,EFCAB4A,SNORA52,LRDD,PNPLA2,SLC25A22,CEND1,RPLP2
SE_02_116900261 chr11:831451-848422 Sample_02_1169 Biliary H69_TGF beta_16h_2 261 1 657 91 3 92 2059 TSPAN4,CD151,POLR2L,CRACR2B,SNORA52,PIDD1,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_010700361 chr11:831493-847891 Sample_02_0107 Endometrium EEC16 361 1 640 91 3 90 2052 TSPAN4,CD151,POLR2L,EFCAB4A,SNORA52,LRDD,PNPLA2,SLC25A22,CEND1,RPLP2
SE_04_000900177 chr11:831497-847508 Sample_04_0009 Lung A549 177 1 630 89 3 90 2049 TSPAN4,CD151,POLR2L,CRACR2B,SNORA52,PIDD1,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_116600256 chr11:831616-848998 Sample_02_1166 Biliary H69_TGF beta_16h_1 256 1 661 91 3 93 2024 TSPAN4,CD151,POLR2L,CRACR2B,SNORA52,PIDD1,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_116800204 chr11:832212-849786 Sample_02_1168 Biliary H69_TGF Vehicle_2 204 1 651 92 1 89 1896 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_085200344 chr11:833078-847536 Sample_02_0852 Mammary gland MCF7L-P 344 1 582 86 1 77 1787 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_026400991 chr11:833106-847529 Sample_02_0264 Skeletal muscle 7250-empty 991 2 580 85 1 77 1779 TSPAN4,CD151,POLR2L,SNORA52,EFCAB4A,LRDD,PNPLA2,SLC25A22,CEND1,RPLP2
SE_02_102900249 chr11:833109-847496 Sample_02_1029 Colon HCT116 249 1 580 85 1 77 1776 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_130900405 chr11:833118-849554 Sample_02_1309 Artery Pulmonary artery endothelial cells_Control 405 3 629 88 1 83 1778 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_018200554 chr11:833126-846705 Sample_02_0182 melanoma LOX-IMVI 554 2 563 83 1 77 1660 TSPAN4,CD151,POLR2L,SNORA52,EFCAB4A,LRDD,PNPLA2,SLC25A22,CEND1,RPLP2
SE_02_078000288 chr11:833183-847535 Sample_02_0780 Liver SMMC-7721 288 1 582 85 1 77 1754 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_130800694 chr11:833212-846267 Sample_02_1308 Artery Pulmonary artery endothelial cells_caMEK5 694 2 554 81 1 77 1632 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_145201231 chr11:833235-846711 Sample_02_1452 Arter pulmonary arterial smooth muscle cells_PAH2_sictrl 1231 3 563 81 1 77 1632 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_144400390 chr11:833991-847215 Sample_02_1444 Adipose SW872_Empty Vector 390 3 555 73 1 77 1674 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_144800247 chr11:834238-846037 Sample_02_1448 Adipose SW872_YAP5SA 247 2 519 68 1 75 1632 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_065300294 chr11:834295-846872 Sample_02_0653 Tracheobronchial epithelial HTBE_H5N1_03h 294 3 537 70 1 77 1632 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_063700318 chr11:834296-847101 Sample_02_0637 Fibroblast fibroblast_WT_GM07492 318 3 541 70 1 77 1647 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_135700686 chr11:834313-846781 Sample_02_1357 Other IC8-deltaEGF-L1596H_GSI_0h 686 4 534 69 1 77 1632 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_137601095 chr11:834315-847194 Sample_02_1376 Pancreas Pancreatic_tumor_associated_fibroblasts_B011C_untreated 1095 7 542 70 1 77 1668 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_065200963 chr11:834320-846823 Sample_02_0652 Tracheobronchial epithelial HTBE_H3N2_mock 963 3 534 69 1 77 1632 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_138000511 chr11:834321-847268 Sample_02_1380 Pancreas Pancreatic_tumor_associated_fibroblasts_CW1_untreated 511 4 543 70 1 77 1686 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_048000722 chr11:834322-847452 Sample_02_0480 Gingival epithelial HGEP 722 4 549 70 1 77 1732 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_063600408 chr11:834329-847250 Sample_02_0636 Skin BJ5ta 408 2 542 70 1 77 1680 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_126000365 chr11:834342-845722 Sample_02_1260 Bone Im-GCT-3504_G34W-repair_4F5 365 2 503 66 1 73 1631 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_142500347 chr11:834344-846338 Sample_02_1425 Shoulder fibroblast_384 347 2 522 68 1 77 1631 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_064600482 chr11:834363-844971 Sample_02_0646 Tracheobronchial epithelial HTBE_H1N1_24h 482 2 473 64 1 73 1630 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_072500281 chr11:834375-846831 Sample_02_0725 Mammary gland MCF10A-YAP5SA_ctrl 281 2 532 69 1 77 1630 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_126301670 chr11:834375-848457 Sample_02_1263 Bone Im-GCT-4072_G34W unedited 1670 3 571 72 1 79 1744 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_006800727 chr11:834387-846893 Sample_02_0068 Skin A375_DMSO 727 4 535 70 1 77 1630 TSPAN4,CD151,POLR2L,SNORA52,EFCAB4A,LRDD,PNPLA2,SLC25A22,CEND1,RPLP2
SE_02_125900510 chr11:834388-846209 Sample_02_1259 Bone Im-GCT-3504_G34W-repair_WT_4C7 510 2 516 68 1 77 1630 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_043700482 chr11:834479-846943 Sample_02_0437 Bone 143B 482 3 534 69 1 77 1605 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_144600324 chr11:834663-845394 Sample_02_1446 Adipose SW872_TAZ_CAMTA1 324 2 481 65 1 73 1563 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_112800556 chr11:834666-846522 Sample_02_1128 Adipose visceral adipose_CTL_HCTR10 556 3 516 67 1 77 1563 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_112000354 chr11:834818-846868 Sample_02_1120 Neonatal foreskin keratinocytes_CTR 354 2 521 67 1 77 1534 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_083901263 chr11:834894-845014 Sample_02_0839 Embryo hNPCs_K755R/+ 1263 2 457 61 1 73 1534 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_112100955 chr11:835180-847480 Sample_02_1121 Neonatal foreskin keratinocytes_Mi2KD 955 3 515 66 1 75 1639 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_01_001200420 chr11:836346-847925 Sample_01_0012 Lung A549_dexamethasone_1h 420 1 454 59 1 65 1534 TSPAN4,CD151,POLR2L,SNORA52,EFCAB4A,LRDD,PNPLA2,SLC25A22,CEND1,RPLP2
SE_02_038000434 chr11:836662-847217 Sample_02_0380 Skeletal muscle RH18 434 1 424 57 1 62 1382 TSPAN4,CD151,POLR2L,SNORA52,EFCAB4A,LRDD,PNPLA2,SLC25A22,CEND1,RPLP2
SE_02_035900200 chr11:836668-847276 Sample_02_0359 Colon Colo741 200 1 424 57 1 62 1388 TSPAN4,CD151,POLR2L,SNORA52,EFCAB4A,LRDD,PNPLA2,SLC25A22,CEND1,RPLP2
SE_02_058400294 chr11:836927-847327 Sample_02_0584 Lung H1299 WT 294 1 413 57 1 60 1356 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
SE_02_141600799 chr11:837646-847139 Sample_02_1416 Brain SF9402 799 1 371 53 1 55 1136 TSPAN4,CD151,POLR2L,SNORA52,PIDD1,CRACR2B,PNPLA2,PANO1,SLC25A22,CEND1,RPLP2
Genomic distribution of SEs associated with POLR2L
Genome Browser

The strength of the tissue affected by the gene

Expression of POLR2L

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)