SEdb 2.0
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Gene overview

Strategies/Algorithm: closest_active Ensembl ID: ENSG00000160199
Gene: PKNOX1 Gene type: protein_coding
Strand: + External links:
Genomic region: chr21:42974510-43033931 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_004300008 chr21:42913254-42975884 Sample_02_0043 Embryo endodermal CyT49_ES_D2 8 20 2049 285 4 7 704 PKNOX1,NDUFV3,WDR4
SE_02_145700163 chr21:42953378-42989045 Sample_02_1457 Embryo HUES8 WT 163 10 1171 147 1 8 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_117200076 chr21:42954015-42982302 Sample_02_1172 Embryo H9 WT 76 3 939 117 1 5 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_157000062 chr21:42954152-43007033 Sample_02_1570 iPSCs EiPSC 62 23 1717 216 1 11 190 PKNOX1,ERVH48-1,MIR5692B
SE_02_157200058 chr21:42954472-42993605 Sample_02_1572 iPSCs FiPSC 58 21 1265 153 1 8 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_156700107 chr21:42954629-42993340 Sample_02_1567 iPSCs CiPSC 107 17 1244 152 1 8 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_041500537 chr21:42954762-42959385 Sample_02_0415 Stomach YCC22 537 2 149 12 0 2 0 PKNOX1
SE_02_012400144 chr21:42954931-42976672 Sample_02_0124 Embryo Embryonic-stem-cells_Naive 144 2 698 84 0 5 157 PKNOX1
SE_02_004200079 chr21:42954994-42976766 Sample_02_0042 Embryo endodermal CyT49_ES_D0 79 6 699 84 0 5 157 PKNOX1
SE_02_075300766 chr21:42955035-42974410 Sample_02_0753 Embryo ES-derived progenitors_FG type 766 3 639 73 0 5 18 ERVH48-1,PKNOX1,MIR5692B
SE_02_001700189 chr21:42955132-42993601 Sample_02_0017 Embryo H9_ESC 189 11 1241 151 1 8 157 PKNOX1
SE_02_012500505 chr21:42955137-42976719 Sample_02_0125 Embryo Embryonic-stem-cells_Primed 505 4 696 83 0 5 157 PKNOX1
SE_02_003800184 chr21:42955146-42993582 Sample_02_0038 Embryo DE 184 7 1240 151 1 8 157 PKNOX1
SE_02_152700498 chr21:42955161-42972214 Sample_02_1527 Embryo naive embryonic stem cell 498 20 581 67 0 2 0 ERVH48-1,PKNOX1,MIR5692B
SE_02_004400516 chr21:42955167-42975936 Sample_02_0044 Embryo endodermal CyT49_ES_D5 516 8 672 79 0 5 157 PKNOX1
SE_00_002400671 chr21:42955167-42976462 Sample_00_0024 Embryo mesendoderm 671 4 690 83 0 5 157 PKNOX1
SE_02_003600275 chr21:42955183-42993691 Sample_02_0036 Embryo H7 275 12 1242 152 1 8 157 PKNOX1
SE_02_074200094 chr21:42955214-42960970 Sample_02_0742 Embryo ESCs_day0 94 1 197 18 0 2 0 ERVH48-1,PKNOX1,MIR5692B
SE_02_067500152 chr21:42955220-42971285 Sample_02_0675 Embryo H1 hESC-derived neural progenitor cells_Smad_0hr 152 9 555 64 0 2 0 ERVH48-1,PKNOX1,MIR5692B
SE_02_055900230 chr21:42955248-42993610 Sample_02_0559 iPSCs FX52 iPSCs dC-T 230 9 1238 151 1 8 157 PKNOX1,ERVH48-1,MIR5692B
SE_04_000100917 chr21:42955254-42976624 Sample_04_0001 Blood heat shocked K562 917 4 689 83 0 5 157 PKNOX1,ERVH48-1,MIR5692B,WDR4,NDUFV3,CBS,U2AF1
SE_02_116100317 chr21:42955348-42971980 Sample_02_1161 Embryo H1_shZNF587 317 4 573 66 0 2 0 ERVH48-1,PKNOX1,MIR5692B
SE_02_052400592 chr21:42955442-42992948 Sample_02_0524 Pancreas iPS derived pancreatic precursor cells_Lane2 592 9 1205 150 1 8 157 PKNOX1,ERVH48-1,MIR5692B
SE_01_003100135 chr21:42955458-42961147 Sample_01_0031 Skin GM23338 135 3 193 18 0 2 0 PKNOX1
SE_01_003300235 chr21:42955500-42976637 Sample_01_0033 Embryo H9 235 4 680 83 0 5 157 PKNOX1
SE_02_116000029 chr21:42955506-43027833 Sample_02_1160 Embryo H1_shLuc 29 14 2331 298 5 45 639 PKNOX1,ERVH48-1,MIR5692B,CBS
SE_02_101700972 chr21:42955529-43026102 Sample_02_1017 Embryo H9_Mesendoderm 24h_Hydroxyurea 972 10 2279 282 5 45 639 PKNOX1,ERVH48-1,MIR5692B,CBS,CRYAA
SE_00_003100687 chr21:42955568-42977085 Sample_00_0031 Placenta placenta 687 5 690 85 0 5 157 PKNOX1
SE_02_074400488 chr21:42955628-42972473 Sample_02_0744 Embryo ES derived cardiac mesoderm_day5 488 8 565 66 0 2 0 ERVH48-1,PKNOX1,MIR5692B
SE_00_001200316 chr21:42955664-42976143 Sample_00_0012 Embryo H1-hESC 316 7 661 80 0 5 157 PKNOX1
SE_00_001300403 chr21:42955707-42960928 Sample_00_0013 Embryo H9 403 6 176 17 0 2 0 PKNOX1
SE_02_006400452 chr21:42955709-42976155 Sample_02_0064 Embryo DN-Early_G1 452 6 661 80 0 5 157 PKNOX1
SE_00_001900201 chr21:42955716-42976603 Sample_00_0019 Dermal fibroblasts iPS-20b 201 8 672 82 0 5 157 PKNOX1
SE_02_067900465 chr21:42955916-42972129 Sample_02_0679 Embryo H1 hESC-derived neural progenitor cells_Smad_24hr 465 7 552 65 0 2 0 ERVH48-1,PKNOX1,MIR5692B
SE_02_086100419 chr21:42955960-42972242 Sample_02_0861 iPSCs SAH_WT 419 5 555 66 0 2 0 ERVH48-1,PKNOX1,MIR5692B
SE_02_067600164 chr21:42956001-42982256 Sample_02_0676 Embryo H1 hESC-derived neural progenitor cells_Smad_3hr 164 9 862 111 1 5 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_103500509 chr21:42956028-42994366 Sample_02_1035 Mammary gland HCC70_Vehicle 509 8 1229 154 1 8 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_103600381 chr21:42956072-43019824 Sample_02_1036 Mammary gland HCC70_XY018 381 25 2065 265 4 39 521 PKNOX1,ERVH48-1,MIR5692B
SE_02_052900046 chr21:42956073-42971957 Sample_02_0529 Heart Heart-derived sendai virus reprogrammed iPSC 46 6 547 64 0 2 0 ERVH48-1,PKNOX1,MIR5692B
SE_02_067800258 chr21:42956096-42972176 Sample_02_0678 Embryo H1 hESC-derived neural progenitor cells_Smad_12hr 258 5 549 65 0 2 0 ERVH48-1,PKNOX1,MIR5692B
SE_02_056000476 chr21:42956100-42972231 Sample_02_0560 iPSCs FX52_Cas9-inactive Tet1_CGG sgRNA 476 6 550 65 0 2 0 ERVH48-1,PKNOX1,MIR5692B
SE_02_067700405 chr21:42956120-42971973 Sample_02_0677 Embryo H1 hESC-derived neural progenitor cells_Smad_6hr 405 5 543 64 0 2 0 ERVH48-1,PKNOX1,MIR5692B
SE_02_004800655 chr21:42956527-42976441 Sample_02_0048 Embryo endodermal CyT49_HE 655 3 631 79 0 5 157 PKNOX1
SE_02_122900936 chr21:42956932-42984625 Sample_02_1229 Haematopoietic and lymphoid tissue bone marrow K562_Control 936 12 892 117 1 6 157 PKNOX1,ERVH48-1,MIR5692B,WDR4,NDUFV3,CBS,U2AF1
SE_02_109900418 chr21:42957865-42990232 Sample_02_1099 Haematopoietic and lymphoid tissue bone marrow K562_DMSO_noIFNG 418 6 1033 134 1 8 157 PKNOX1,ERVH48-1,MIR5692B,WDR4,NDUFV3,CBS,U2AF1
SE_02_074500103 chr21:42958938-42993490 Sample_02_0745 Embryo ES derived cardiac progenitor cells_day7 103 12 1109 141 1 8 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_074600228 chr21:42962336-42993546 Sample_02_0746 Embryo ES derived primitive cardiomyocite_day15 228 10 992 132 1 6 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_104602190 chr21:42964128-43022654 Sample_02_1046 Peripheral blood CD4+ cells_CTCL1145 2190 14 1881 244 4 39 592 PKNOX1,ERVH48-1,MIR5692B
SE_02_143300326 chr21:42964143-43046773 Sample_02_1433 Bone A673 STAG2 null 326 30 2707 451 7 93 1129 PKNOX1,ERVH48-1,MIR5692B
SE_02_075500765 chr21:42967330-42974300 Sample_02_0755 Embryo ES-derived progenitors_DE FOXA2 -/- 765 1 236 26 0 3 0 ERVH48-1,PKNOX1,MIR5692B
SE_02_075200498 chr21:42967585-42974300 Sample_02_0752 Embryo ES-derived progenitors_DE_wild type 498 1 229 24 0 3 0 ERVH48-1,PKNOX1,MIR5692B
SE_02_092200553 chr21:42969278-43046163 Sample_02_0922 Heart fetal heart_PCW10_12434 553 19 2510 412 7 93 1129 PKNOX1,ERVH48-1,MIR5692B
SE_02_004900592 chr21:42970648-42976640 Sample_02_0049 Embryo endodermal CyT49_GTtoH 592 1 183 24 0 3 157 PKNOX1
SE_02_111600576 chr21:42971427-42981175 Sample_02_1116 Haematopoietic and lymphoid tissue bone marrow K562_native 576 2 296 41 0 3 157 PKNOX1,ERVH48-1,MIR5692B,CBS,WDR4,NDUFV3
SE_02_057600976 chr21:42971548-42992516 Sample_02_0576 Blood HEL_sgLKB1e2 976 8 642 81 1 6 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_077101177 chr21:42971557-42997680 Sample_02_0771 Ovary OVCA429_shGRHL2 1177 13 804 108 1 6 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_057900784 chr21:42971565-42983891 Sample_02_0579 Blood HEL_sgNeg2 784 5 378 55 1 3 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_143200253 chr21:42971651-43046673 Sample_02_1432 Bone A673 STAG2 WT 253 32 2431 413 7 93 1129 PKNOX1,ERVH48-1,MIR5692B
SE_02_121800980 chr21:42971667-42990988 Sample_02_1218 Bone marrow Daudi 980 6 584 80 1 6 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_058000849 chr21:42971671-42983688 Sample_02_0580 Blood HEL_sgSIK3e4 849 3 369 55 1 3 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_126701485 chr21:42971675-42997931 Sample_02_1267 Bone Im-GCT-4072_G34W 1485 4 803 108 1 6 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_104700303 chr21:42971808-43109584 Sample_02_1047 Peripheral blood CD4+ cells_CTCL1181 303 42 4498 536 17 159 4254 PKNOX1,CBS,U2AF1,ERVH48-1,MIR5692B
SE_02_064500648 chr21:42971870-42976625 Sample_02_0645 Tracheobronchial epithelial HTBE_H1N1_18h 648 2 119 17 0 3 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_122700719 chr21:42971878-42997373 Sample_02_1227 Bone marrow U266 719 5 785 104 1 6 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_074700755 chr21:42971983-42997233 Sample_02_0747 Embryo ES derived ventricular cardiomyocyte_day80 755 9 776 104 1 6 157 PKNOX1,ERVH48-1,MIR5692B
SE_02_082300136 chr21:42972027-42977876 Sample_02_0823 Haematopoietic and lymphoid tissue SET-2_insR_GSK-LSD1 136 2 164 23 0 3 157 PKNOX1,ERVH48-1,MIR5692B
SE_00_001500506 chr21:42973512-42998249 Sample_00_0015 Lung IMR-90 506 5 766 103 1 6 157 PKNOX1
SE_02_092300995 chr21:42976526-43046054 Sample_02_0923 Heart fetal heart_PCW10_12522 995 14 2291 384 7 90 972 PKNOX1,MIR5692B
SE_02_158300960 chr21:42976676-42998364 Sample_02_1583 Fetal lung IMR90_empty_GM 960 14 691 91 1 3 0 PKNOX1,MIR5692B,CBS,AP001631.10
SE_01_010500532 chr21:43015606-43046219 Sample_01_0105 Thyroid gland thyroid gland_54y 532 12 1033 224 5 70 787 PKNOX1
SE_02_081800442 chr21:43019339-43054647 Sample_02_0818 Ovary High-grade serous ovarian cancer 442 9 1217 256 4 58 797 PKNOX1,CBS
SE_02_077100978 chr21:43019630-43046188 Sample_02_0771 Ovary OVCA429_shGRHL2 978 16 896 203 3 56 608 PKNOX1
SE_02_069800220 chr21:43023738-43046291 Sample_02_0698 Lung NCI-H1048-cas9_sgPOU2F3 220 4 769 194 3 54 537 PKNOX1
SE_02_069700339 chr21:43024927-43052843 Sample_02_0697 Lung NCI-H1048-cas9_sgHROSA 339 7 960 231 4 54 516 PKNOX1
SE_02_103601428 chr21:43034564-43076853 Sample_02_1036 Mammary gland HCC70_XY018 1428 11 1512 222 7 66 2104 CBS,PKNOX1
SE_02_104601823 chr21:43037024-43092604 Sample_02_1046 Peripheral blood CD4+ cells_CTCL1145 1823 14 1960 218 8 66 2104 CBS,PKNOX1
SE_02_082100565 chr21:43103586-43111538 Sample_02_0821 Haematopoietic and lymphoid tissue SET-2_WT_GSK-LSD1 565 2 221 5 1 0 256 U2AF1,PKNOX1
SE_02_082000396 chr21:43103883-43110456 Sample_02_0820 Haematopoietic and lymphoid tissue SET-2_WT_DMSO 396 2 184 5 1 0 256 U2AF1,PKNOX1
SE_02_082200360 chr21:43103989-43109912 Sample_02_0822 Haematopoietic and lymphoid tissue SET-2_insR_DMSO 360 2 165 2 1 0 256 U2AF1,PKNOX1
SE_02_057601285 chr21:43104309-43117937 Sample_02_0576 Blood HEL_sgLKB1e2 1285 7 431 4 1 0 247 U2AF1,PKNOX1
SE_02_058001173 chr21:43104594-43117269 Sample_02_0580 Blood HEL_sgSIK3e4 1173 3 401 4 1 0 228 U2AF1,PKNOX1
SE_02_082300387 chr21:43106601-43109656 Sample_02_0823 Haematopoietic and lymphoid tissue SET-2_insR_GSK-LSD1 387 1 93 0 0 0 146 U2AF1,PKNOX1
SE_02_082100203 chr21:43129898-43157799 Sample_02_0821 Haematopoietic and lymphoid tissue SET-2_WT_GSK-LSD1 203 6 927 16 3 0 0 PKNOX1
SE_02_082000311 chr21:43130332-43157085 Sample_02_0820 Haematopoietic and lymphoid tissue SET-2_WT_DMSO 311 5 894 16 2 0 0 PKNOX1
SE_02_082200181 chr21:43130505-43154459 Sample_02_0822 Haematopoietic and lymphoid tissue SET-2_insR_DMSO 181 5 792 16 2 0 0 PKNOX1
SE_02_082300191 chr21:43139134-43154347 Sample_02_0823 Haematopoietic and lymphoid tissue SET-2_insR_GSK-LSD1 191 6 542 6 0 0 0 PKNOX1
Genomic distribution of SEs associated with PKNOX1
Genome Browser

The strength of the tissue affected by the gene

Expression of PKNOX1

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)