SEdb 2.0
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  2. Super-enhancer search result of gene-based

Gene overview

Strategies/Algorithm: closest_active Ensembl ID: ENSG00000140718
Gene: FTO Gene type: protein_coding
Strand: + External links:
Genomic region: chr16:53701692-54158512 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_076500255 chr16:53706584-53782130 Sample_02_0765 Prostate 22RV1-DHT-DMSO_6h 255 26 1855 142 63 298 0 FTO,RPGRIP1L
SE_02_116200166 chr16:53713964-53837047 Sample_02_1162 Stomach YCC11 166 49 3115 252 127 358 133 FTO,RPGRIP1L
SE_02_044200544 chr16:53715189-53784279 Sample_02_0442 Bone MG63.3 544 34 1723 142 67 278 0 FTO,RPGRIP1L
SE_01_005700394 chr16:53724701-53785759 Sample_01_0057 Pancreas duct PANC-1 394 14 1575 141 71 234 0 FTO,RPGRIP1L
SE_02_019400027 chr16:53727360-53783085 Sample_02_0194 Kidney Patient_x750T 27 8 1427 123 61 196 0 FTO,RPGRIP1L
SE_02_059000201 chr16:53731421-53792788 Sample_02_0590 Cervix HeLa Kyoto_Luci PWWP2A siRNA 201 15 1608 146 99 214 0 FTO,RPGRIP1L
SE_02_135900364 chr16:53731711-53792855 Sample_02_1359 Other IC8-deltaEGF-L1596H_GSI_4h 364 28 1605 146 99 214 0 FTO,RPGRIP1L
SE_02_058900176 chr16:53731862-53792583 Sample_02_0589 Cervix HeLa Kyoto_Luci siRNA 176 23 1593 145 99 213 0 FTO,RPGRIP1L
SE_02_029400785 chr16:53731887-53793616 Sample_02_0294 Pancreatic L3-6_DMSO 785 10 1613 147 101 215 0 FTO,RPGRIP1L
SE_02_009500026 chr16:53732023-53842467 Sample_02_0095 Mammary gland MDA-MB-468 26 17 2870 247 122 268 133 FTO,RPGRIP1L
SE_02_154000242 chr16:53732167-53823434 Sample_02_1540 Nasopharyngeal HK1 242 27 2380 191 117 236 27 FTO,RPGRIP1L
SE_02_077001366 chr16:53732244-53785480 Sample_02_0770 Ovary OVCA429_shLuc 1366 22 1380 122 69 204 0 FTO,RPGRIP1L
SE_02_055500472 chr16:53732283-53773307 Sample_02_0555 Other HAP1_WT 472 11 1101 95 41 144 0 FTO,RPGRIP1L
SE_02_058800435 chr16:53732288-53784652 Sample_02_0588 Cervix HeLa Kyoto_untreated 435 19 1353 115 62 197 0 FTO,RPGRIP1L
SE_02_150301106 chr16:53739884-53786383 Sample_02_1503 Brain SHEP-21N_DOX_2h_NOSPIKE 1106 16 1186 102 69 193 0 FTO,RPGRIP1L
SE_02_006300512 chr16:53740351-53823127 Sample_02_0063 Skin Keratinocytes 512 11 2128 165 112 216 27 FTO,RPGRIP1L
SE_02_072100306 chr16:53741058-53783121 Sample_02_0721 Pancreas HPAFII_TP63dN_DOX 306 24 1064 86 55 173 0 FTO,RPGRIP1L
SE_01_004500618 chr16:53741170-53785604 Sample_01_0045 Mammary gland mammary-epithelial-cell 618 8 1131 95 64 183 0 FTO,RPGRIP1L
SE_02_071900488 chr16:53741763-53781626 Sample_02_0719 Pancreas SUIT2_TP63dN_DOX 488 13 1016 81 51 169 0 FTO,RPGRIP1L
SE_02_086800200 chr16:53741784-53788430 Sample_02_0868 Bone marrow Bone marrow derived hMSC_d10 200 24 1204 112 84 186 0 FTO,RPGRIP1L
SE_02_042800103 chr16:53741978-53791404 Sample_02_0428 Kidney 12364284_VHL- 103 22 1280 116 91 191 0 FTO,RPGRIP1L
SE_02_070500523 chr16:53742910-53776708 Sample_02_0705 Pancreas AsPC1 WT 523 12 884 70 42 162 0 FTO,RPGRIP1L
SE_02_072400238 chr16:53743329-53776130 Sample_02_0724 Pancreatic duct AsPC1_GFP_DOX 238 15 861 68 41 154 0 FTO,RPGRIP1L
SE_02_071500406 chr16:53743745-53782233 Sample_02_0715 Pancreas SUIT2_TP63dN 406 9 980 79 51 167 0 FTO,RPGRIP1L
SE_02_076600453 chr16:53743804-53789426 Sample_02_0766 Ovary PEO1 453 32 1188 112 88 187 0 FTO,RPGRIP1L
SE_02_059400868 chr16:53743936-53828531 Sample_02_0594 iPSC-derived neural progenitors 868 16 2187 172 113 228 133 FTO,RPGRIP1L
SE_02_127901686 chr16:53743982-53791181 Sample_02_1279 Bone Mesenchymal stem cells 1686 9 1230 113 91 189 0 FTO,RPGRIP1L
SE_02_042900096 chr16:53744016-53788552 Sample_02_0429 Kidney 12364284_VHL+ 96 16 1155 112 86 184 0 FTO,RPGRIP1L
SE_02_043000043 chr16:53744016-53791368 Sample_02_0430 Kidney 12364284 43 14 1234 114 91 189 0 FTO,RPGRIP1L
SE_02_150200586 chr16:53744031-53785907 Sample_02_1502 Brain SHEP-21N_DOX_24h_NOSPIKE 586 20 1075 94 65 181 0 FTO,RPGRIP1L
SE_02_000900300 chr16:53744198-53788837 Sample_02_0009 Kidney 786-O_wtVHL 300 11 1166 112 88 184 0 FTO,RPGRIP1L
SE_02_072000306 chr16:53744287-53776564 Sample_02_0720 Pancreas AsPC1_TP63dN_DOX 306 11 848 68 41 156 0 FTO,RPGRIP1L
SE_02_123400211 chr16:53744384-53809971 Sample_02_1234 Mammary gland T47D_Full 211 29 1685 146 107 198 0 FTO,RPGRIP1L
SE_02_108400233 chr16:53744447-53773085 Sample_02_1084 Blood KBM7-derived near haploid cells 233 15 760 66 36 116 0 FTO,RPGRIP1L
SE_02_053000770 chr16:53744491-53788195 Sample_02_0530 Mammary gland MCF10A 770 16 1124 107 80 176 0 FTO,RPGRIP1L
SE_02_141001237 chr16:53744680-53789493 Sample_02_1410 Brain GSC6 1237 13 1172 112 88 177 0 FTO,RPGRIP1L
SE_02_066100508 chr16:53745024-53789558 Sample_02_0661 Mammary gland MCF10DCIS-TetTCF7 508 20 1164 112 88 166 0 FTO,RPGRIP1L
SE_02_150101049 chr16:53745274-53786130 Sample_02_1501 Brain SHEP-21N_NOSPIKE 1049 20 1055 96 68 148 0 FTO,RPGRIP1L
SE_02_150700409 chr16:53745355-53789383 Sample_02_1507 Brain SHEP-21N_DOX_24h 409 12 1148 111 88 153 0 FTO,RPGRIP1L
SE_02_070900859 chr16:53746245-53782946 Sample_02_0709 Pancreas hT85_organoid 859 11 928 81 55 135 0 FTO,RPGRIP1L
SE_02_004001036 chr16:53754658-53778967 Sample_02_0040 Embryo PFG 1036 8 606 64 47 121 0 FTO
SE_01_000100119 chr16:53755115-53780937 Sample_01_0001 Prostate 22Rv1 119 4 640 67 49 114 0 FTO
SE_02_075400709 chr16:53755341-53776928 Sample_02_0754 Embryo ES-derived progenitors Pancreatic Progenitors 1 WT 709 4 547 60 43 106 0 FTO
SE_02_003000067 chr16:53755637-53785071 Sample_02_0030 Kidney human kidney proximal tubule cells 67 7 730 79 61 126 0 FTO
SE_02_152300600 chr16:53755899-53787783 Sample_02_1523 Lung A549 DMSO 600 11 796 94 79 129 0 FTO
SE_02_027200109 chr16:53757678-53776644 Sample_02_0272 Kidney 20431713T 109 5 490 51 42 93 0 FTO
SE_02_055400207 chr16:53762069-53789521 Sample_02_0554 Other Aska shSSX 207 12 690 75 86 118 0 FTO
SE_02_126601064 chr16:53765974-53778131 Sample_02_1266 Bone Im-GCT-4072_G34W-repair_WT_E3 1064 7 281 24 34 68 0 FTO
SE_02_125300342 chr16:53766166-53829292 Sample_02_1253 Mammary gland CAMA1 ER+/FGFR1-amplified 342 21 1599 125 99 136 133 FTO
SE_02_126501027 chr16:53766234-53789669 Sample_02_1265 Bone Im-GCT-4072_G34W-repair_WT_D6 1027 5 588 63 74 96 0 FTO
SE_02_067100261 chr16:53766347-53817891 Sample_02_0671 Mammary gland breast cancer_DSG 261 24 1303 104 96 112 27 FTO
SE_02_126401087 chr16:53766427-53789837 Sample_02_1264 Bone Im-GCT-4072_G34W KO 1087 7 587 62 74 96 0 FTO
SE_02_054900134 chr16:53766457-53784499 Sample_02_0549 Other Aska shCt 134 6 414 35 40 79 0 FTO
SE_02_094800507 chr16:53766658-53793274 Sample_02_0948 Pharyng Detroit562 507 9 649 66 77 99 0 FTO
SE_02_135800620 chr16:53766849-53792849 Sample_02_1358 Other IC8-deltaEGF-L1596H_GSI_2h 620 13 637 63 74 98 0 FTO
SE_02_039400132 chr16:53767514-53810337 Sample_02_0394 Mammary gland T-47D_2 132 12 1061 92 85 100 22 FTO
SE_02_131000490 chr16:53767535-53793149 Sample_02_1310 Bone marrow ASMSCs 490 4 625 62 72 87 0 FTO
SE_02_131100434 chr16:53767673-53791432 Sample_02_1311 Bone marrow HDMSCs 434 5 587 59 68 85 0 FTO
SE_02_094700644 chr16:53767839-53792888 Sample_02_0947 Tongue Cal27 644 9 616 61 71 85 0 FTO
SE_02_135600801 chr16:53767953-53789627 Sample_02_1356 Umbilical cord umbilical cord-derived mesenchymal stem cells_Young 801 5 539 57 65 83 0 FTO
SE_02_109200657 chr16:53767964-53810508 Sample_02_1092 Mammary gland T47D_shCtrl_24hr 657 21 1056 91 85 98 27 FTO
SE_02_008800443 chr16:53768010-53790092 Sample_02_0088 Umbilical cord umbilical-cord-derived-mesenchymal-stem-cells_SGA_cycle_0 443 4 553 57 67 83 0 FTO
SE_02_053200282 chr16:53768013-53809240 Sample_02_0532 Mammary gland T47D 282 13 1024 90 83 96 0 FTO
SE_02_151300519 chr16:53768043-53781057 Sample_02_1513 Lung Transitional AT2->1 cells 519 6 297 22 26 61 0 FTO
SE_02_080900156 chr16:53768047-53810790 Sample_02_0809 Mammary gland T47D Serum 156 10 1064 91 85 98 27 FTO
SE_02_123300692 chr16:53768068-53788059 Sample_02_1233 Lung PC9_miR-4497 mimic 692 7 479 52 57 77 0 FTO
SE_02_123100706 chr16:53768084-53787932 Sample_02_1231 Lung PC9_siMED13L-1 706 11 475 50 55 77 0 FTO
SE_02_157101079 chr16:53768094-53789912 Sample_02_1571 Fibroblast Fibroblast cells 1079 6 546 56 66 83 0 FTO
SE_02_123200492 chr16:53768107-53788446 Sample_02_1232 Lung PC9_siMED13L-2 492 7 496 54 60 78 0 FTO
SE_02_109000458 chr16:53768134-53810041 Sample_02_1090 Mammary gland T47D_shCtrl_8hr 458 17 1041 90 83 96 0 FTO
SE_02_109300614 chr16:53768187-53809957 Sample_02_1093 Mammary gland T47D_shCtrl_shRING1B_24hr 614 18 1037 90 83 92 0 FTO
SE_02_108800506 chr16:53768317-53810299 Sample_02_1088 Mammary gland T47D_shCtrl_45min 506 20 1045 90 83 94 19 FTO
SE_02_108600633 chr16:53768320-53809939 Sample_02_1086 Mammary gland T47D_shCtrl_0hr 633 22 1036 90 83 92 0 FTO
SE_02_005701115 chr16:53768747-53789761 Sample_02_0057 Mammary gland vHMEC 1115 9 523 55 63 78 0 FTO
SE_02_151200746 chr16:53769242-53778123 Sample_02_1512 Lung Purified AT2 cells 746 5 202 15 20 44 0 FTO
SE_02_008900473 chr16:53773269-53789973 Sample_02_0089 Umbilical cord umbilical-cord-derived-mesenchymal-stem-cells_SGA_cycle_3 473 6 423 46 54 68 0 FTO
SE_02_103602430 chr16:53780330-53847750 Sample_02_1036 Mammary gland HCC70_XY018 2430 23 1753 150 68 92 165 FTO
SE_02_005600634 chr16:53803329-53840121 Sample_02_0056 Mammary gland HMEC 634 7 956 73 13 48 133 FTO
SE_02_086701332 chr16:53805724-53824756 Sample_02_0867 Bone marrow Bone marrow derived hMSC_d0 1332 18 497 24 7 16 27 FTO
SE_02_127901587 chr16:53805977-53824612 Sample_02_1279 Bone Mesenchymal stem cells 1587 5 485 23 7 15 27 FTO
SE_02_137901211 chr16:53808159-53823320 Sample_02_1379 Pancreas Pancreatic_tumor_associated_fibroblasts_PS1_untreated 1211 9 399 18 7 11 27 FTO
SE_02_047401302 chr16:53808389-53823144 Sample_02_0474 Fibroblast umbilical cord Fibroblast 1302 4 390 17 7 11 27 FTO
SE_02_157100251 chr16:53808458-53823706 Sample_02_1571 Fibroblast Fibroblast cells 251 3 403 18 7 11 27 FTO
SE_02_135600587 chr16:53808580-53823457 Sample_02_1356 Umbilical cord umbilical cord-derived mesenchymal stem cells_Young 587 3 399 18 7 11 27 FTO
SE_02_135500894 chr16:53808589-53823806 Sample_02_1355 Umbilical cord umbilical cord-derived mesenchymal stem cells_old 894 3 407 18 7 11 27 FTO
SE_02_023000394 chr16:53808638-53821855 Sample_02_0230 Umbilical cord ID60 394 5 343 16 7 11 27 FTO
SE_02_009100263 chr16:53808640-53823240 Sample_02_0091 Umbilical cord umbilical-cord-derived-mesenchymal-stem-cells_Control_cycle_0 263 3 388 17 7 11 27 FTO
SE_02_008800271 chr16:53808702-53823123 Sample_02_0088 Umbilical cord umbilical-cord-derived-mesenchymal-stem-cells_SGA_cycle_0 271 3 384 17 7 11 27 FTO
SE_02_009200285 chr16:53808751-53822833 Sample_02_0092 Umbilical cord umbilical-cord-derived-mesenchymal-stem-cells_Control_cycle_3 285 5 375 17 7 11 27 FTO
SE_02_008900493 chr16:53808817-53822350 Sample_02_0089 Umbilical cord umbilical-cord-derived-mesenchymal-stem-cells_SGA_cycle_3 493 3 356 16 7 11 27 FTO
SE_01_004501111 chr16:53863926-53882644 Sample_01_0045 Mammary gland mammary-epithelial-cell 1111 4 440 4 2 23 91 FTO
SE_02_009700840 chr16:53864659-53882669 Sample_02_0097 Foreskin Epidermal-Stem-Cells_shCTRL 840 4 424 3 2 21 91 FTO
SE_02_032200480 chr16:53878653-53938687 Sample_02_0322 Colon Caco-2 480 6 1577 21 6 379 229 FTO
SE_01_002500330 chr16:53888413-53960791 Sample_01_0025 Haematopoietic and lymphoid tissue blood DND-41 330 8 1933 21 6 521 143 FTO
SE_02_024400495 chr16:53892689-53915168 Sample_02_0244 Foreskin foreskin_D11 495 6 616 9 5 156 0 FTO
SE_02_068400371 chr16:53912619-53961700 Sample_02_0684 Lung DMS79 371 18 1291 13 3 408 88 FTO,FTO-IT1
SE_00_001000716 chr16:53913291-53921766 Sample_00_0010 Embryo endodermal-cell 716 2 216 8 1 65 34 FTO
SE_02_022500473 chr16:53923953-53956072 Sample_02_0225 Haematopoietic and lymphoid tissue PF-382 473 3 816 2 1 253 54 FTO
SE_02_033200509 chr16:53942589-53996324 Sample_02_0332 Haematopoietic and lymphoid tissue MOLM14_DMSO_9 509 10 1436 9 16 437 44 FTO
SE_02_022400067 chr16:53945049-53996822 Sample_02_0224 Haematopoietic and lymphoid tissue P12-ICHIKAWA 67 11 1393 8 16 427 44 FTO
Genomic distribution of SEs associated with FTO
Genome Browser

The strength of the tissue affected by the gene

Expression of FTO

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)