SEdb 2.0
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Gene overview

Strategies/Algorithm: closest_active Ensembl ID: ENSG00000179335
Gene: CLK3 Gene type: protein_coding
Strand: + External links:
Genomic region: chr15:74598500-74645414 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_074600110 chr15:74530950-74664534 Sample_02_0746 Embryo ES derived primitive cardiomyocite_day15 110 47 3058 247 18 671 5378 CLK3,ARID3B,EDC3
SE_02_138700153 chr15:74534855-74631734 Sample_02_1387 Peripheral blood Mac-1_ALK- 153 30 2281 178 16 583 4860 CLK3,ARID3B,EDC3
SE_02_108300126 chr15:74541169-74637543 Sample_02_1083 Macula macula 126 41 2267 172 16 611 5161 CLK3,ARID3B,EDC3
SE_02_108200219 chr15:74543187-74621676 Sample_02_1082 Retina retina 219 25 1858 146 13 422 3293 CLK3,ARID3B
SE_02_033001062 chr15:74558729-74598976 Sample_02_0330 Endoderm MHG 1062 8 953 80 8 221 1449 ARID3B,CLK3
SE_02_040800599 chr15:74562611-74600194 Sample_02_0408 Kidney G401_Dox 599 8 893 73 8 220 1593 ARID3B,CLK3
SE_02_110500211 chr15:74568249-74630484 Sample_02_1105 Brain NBL-S 211 24 1504 117 15 436 4317 CLK3,ARID3B
SE_02_030400526 chr15:74568343-74617384 Sample_02_0304 Neuroblastoma N206 526 9 1188 96 10 281 2688 ARID3B,CLK3
SE_02_030800240 chr15:74569149-74617153 Sample_02_0308 Neuroblastoma SJNB1 240 6 1166 95 10 273 2688 ARID3B,CLK3
SE_02_030000264 chr15:74569249-74617419 Sample_02_0300 Neuroblastoma CLB-PE 264 7 1166 95 10 274 2688 ARID3B,CLK3
SE_02_031200659 chr15:74569611-74632186 Sample_02_0312 Neuroblastoma SK-N-BE_2-C 659 11 1507 119 15 432 4644 CLK3,ARID3B,EDC3
SE_02_123500404 chr15:74570006-74617051 Sample_02_1235 Brain Neuroblastoma PDX tumour cells 404 17 1147 95 10 273 2688 CLK3,ARID3B
SE_00_001000667 chr15:74575016-74599168 Sample_00_0010 Embryo endodermal-cell 667 4 587 52 8 142 1176 ARID3B,CLK3
SE_02_104700212 chr15:74576502-74633305 Sample_02_1047 Peripheral blood CD4+ cells_CTCL1181 212 28 1358 106 15 407 4481 CLK3,ARID3B,EDC3
SE_02_104900204 chr15:74576770-74636686 Sample_02_1049 Peripheral blood CD4+ cell_ROMI 204 43 1427 111 15 418 4575 CLK3,ARID3B,EDC3
SE_02_104600501 chr15:74577636-74633317 Sample_02_1046 Peripheral blood CD4+ cells_CTCL1145 501 31 1336 103 15 407 4481 CLK3,ARID3B,EDC3
SE_02_104800226 chr15:74577759-74642853 Sample_02_1048 Peripheral blood CD4+ cell_UNTREATED 226 16 1528 113 15 428 4646 CLK3,ARID3B,EDC3
SE_02_116000706 chr15:74579109-74610968 Sample_02_1160 Embryo H1_shLuc 706 6 769 59 10 144 2014 ARID3B,CLK3
SE_02_152700564 chr15:74579208-74598785 Sample_02_1527 Embryo naive embryonic stem cell 564 10 490 34 7 126 1076 ARID3B,CLK3
SE_02_050600065 chr15:74580211-74684429 Sample_02_0506 Esophagus TE5_1 65 51 2393 164 16 477 4926 CLK3,ARID3B,EDC3,CYP1A1
SE_02_051700064 chr15:74580212-74688705 Sample_02_0517 Esophagus TE5 64 51 2476 173 16 478 4976 CLK3,ARID3B,EDC3,CYP1A1
SE_02_039600611 chr15:74580548-74643779 Sample_02_0396 Skin NHEK-D 611 20 1491 106 14 428 4646 CLK3,ARID3B,EDC3
SE_02_050500175 chr15:74580567-74653627 Sample_02_0505 Esophagus KYSE70_1 175 25 1707 122 15 429 4646 CLK3,ARID3B,EDC3
SE_02_051600171 chr15:74580567-74653645 Sample_02_0516 Esophagus KYSE70 171 24 1707 122 15 429 4646 CLK3,ARID3B,EDC3
SE_02_005600382 chr15:74580654-74624643 Sample_02_0056 Mammary gland HMEC 382 11 1064 76 12 308 3229 ARID3B,CLK3
SE_04_000100931 chr15:74580817-74617270 Sample_04_0001 Blood heat shocked K562 931 5 878 63 9 209 2354 CLK3,ARID3B,ULK3,COX5A
SE_02_104300426 chr15:74580956-74637508 Sample_02_1043 Peripheral blood Peripheral blood cells_CTCL1200 426 29 1350 94 14 411 4575 CLK3,ARID3B,EDC3
SE_02_074400337 chr15:74583087-74611044 Sample_02_0744 Embryo ES derived cardiac mesoderm_day5 337 9 688 50 8 130 2014 ARID3B,CLK3
SE_02_074700155 chr15:74583975-74664691 Sample_02_0747 Embryo ES derived ventricular cardiomyocyte_day80 155 39 1861 137 15 437 4737 CLK3,ARID3B,EDC3
SE_02_001900360 chr15:74584230-74616990 Sample_02_0019 Embryo Neural crest cells 360 10 804 58 8 196 2354 ARID3B,CLK3
SE_02_055200273 chr15:74584364-74641047 Sample_02_0552 Other SYO1 shCt 273 16 1349 97 13 407 4646 CLK3,ARID3B,EDC3
SE_02_092101043 chr15:74584469-74617727 Sample_02_0921 Heart embryonic heart_CS22 1043 10 817 61 8 197 2354 CLK3,ARID3B
SE_02_027500470 chr15:74587836-74617108 Sample_02_0275 Retina FW14 470 4 720 57 8 173 2354 ARID3B,CLK3
SE_02_021601373 chr15:74589551-74603985 Sample_02_0216 Skin NHEK_scramble 1373 5 368 30 6 73 1471 ARID3B,CLK3
SE_02_055300297 chr15:74595002-74620063 Sample_02_0553 Other HSSY2 shCt 297 10 617 54 7 165 2103 CLK3,ARID3B
SE_02_146700252 chr15:74597188-74643498 Sample_02_1467 Blood HUDEP-2_LRFKO 252 9 1072 80 9 322 3866 CLK3,ARID3B,EDC3
SE_02_146800364 chr15:74597189-74642980 Sample_02_1468 Blood HUDEP-2_WT 364 10 1062 80 9 315 3866 CLK3,ARID3B,EDC3
SE_02_083501108 chr15:74597568-74627309 Sample_02_0835 Bone marrow TEX-HIST1H3H-K27M-Rx_cells 1108 5 714 55 8 218 2627 CLK3,ARID3B
SE_02_146600280 chr15:74597720-74643466 Sample_02_1466 Blood HUDEP-2_BCL11AKO 280 9 1060 79 9 321 3773 CLK3,ARID3B,EDC3
SE_02_136300200 chr15:74597808-74623441 Sample_02_1363 Blood Hudep2 200 8 623 49 6 199 2094 CLK3,ARID3B
SE_02_140500221 chr15:74597867-74624190 Sample_02_1405 Embryonic kidney HEK293_siBAHD1_W667G_mutant 221 9 635 51 7 200 2231 CLK3,ARID3B
SE_02_109600486 chr15:74597969-74617096 Sample_02_1096 Blood CD34 Erythroid cells_Don003 486 3 462 38 4 99 1425 CLK3,ARID3B
SE_02_101800107 chr15:74598008-74617188 Sample_02_1018 Erythroblast CD34+ Hematopoietic stem/progenitor cells_12 days 107 5 463 38 4 100 1421 CLK3,ARID3B,UBL7
SE_02_082600994 chr15:74598471-74626978 Sample_02_0826 Stomach gastric tumor 994 10 681 52 7 203 2433 CLK3
SE_02_146001219 chr15:74598532-74617623 Sample_02_1460 Blood Mutz-3 1219 3 449 36 4 89 1329 CLK3
SE_02_001600145 chr15:74602688-74619357 Sample_02_0016 Blood erythroblasts 145 1 419 35 2 108 1051 CLK3
SE_01_008400833 chr15:74613884-74632291 Sample_01_0084 Spleen spleen 833 3 436 30 5 220 2315 CLK3,EDC3
SE_02_122700356 chr15:74613952-74632041 Sample_02_1227 Bone marrow U266 356 8 429 30 5 219 2266 CLK3,EDC3
SE_00_003901197 chr15:74614002-74617155 Sample_00_0039 Spleen spleen_3y 1197 1 78 6 0 60 340 CLK3
SE_02_076500401 chr15:74614060-74645257 Sample_02_0765 Prostate 22RV1-DHT-DMSO_6h 401 10 725 51 5 280 2632 CLK3,EDC3
SE_02_074500797 chr15:74614133-74622981 Sample_02_0745 Embryo ES derived cardiac progenitor cells_day7 797 2 218 17 2 158 969 CLK3
SE_01_010400551 chr15:74614192-74671025 Sample_01_0104 Lung upper lobe of left lung 551 11 1249 89 7 298 2723 CLK3,EDC3,CYP1A1,CYP1A2
SE_02_101701722 chr15:74614207-74644217 Sample_02_1017 Embryo H9_Mesendoderm 24h_Hydroxyurea 1722 6 689 49 5 280 2632 CLK3,EDC3
SE_02_081800797 chr15:74614254-74619310 Sample_02_0818 Ovary High-grade serous ovarian cancer 797 2 133 14 0 81 392 CLK3
SE_02_087501116 chr15:74614271-74643305 Sample_02_0875 Peripheral blood Peripheral blood-derived mast cells 1116 9 661 47 5 279 2632 CLK3,EDC3
SE_02_046601205 chr15:74614282-74665286 Sample_02_0466 Adipose visceral adipocytes 1205 17 1126 84 7 298 2723 CLK3,EDC3
SE_02_059100522 chr15:74614296-74617142 Sample_02_0591 PBMCs adult CD4+CD25-CD45RA+CD27+ naive T cells 522 1 70 6 0 60 340 CLK3
SE_02_081601797 chr15:74614333-74617123 Sample_02_0816 Ovary Clear cell ovarian cancer 1797 1 68 6 0 60 340 CLK3
SE_02_149201390 chr15:74614377-74643214 Sample_02_1492 Peripheral blood CD34+ derived peripheral blood-derived mast cells 1390 7 658 47 5 276 2632 CLK3,EDC3
SE_02_046500557 chr15:74614389-74666303 Sample_02_0465 Adipose subcutaneous adipocytes 557 12 1148 85 7 298 2723 CLK3,EDC3
SE_02_064502145 chr15:74614670-74617036 Sample_02_0645 Tracheobronchial epithelial HTBE_H1N1_18h 2145 1 63 6 0 60 340 CLK3
SE_02_122400432 chr15:74614790-74642842 Sample_02_1224 Bone marrow normal plasma cell 432 9 645 45 5 273 2632 CLK3,EDC3
SE_01_011200557 chr15:74614819-74617028 Sample_01_0112 Embryonic kidney HEK293_encode 557 1 59 4 0 60 333 CLK3
SE_02_088600858 chr15:74614928-74631834 Sample_02_0886 Skin foreskin_ p63KLF4 858 4 406 28 5 210 2200 CLK3,EDC3
SE_02_151000490 chr15:74617275-74660326 Sample_02_1510 Lung H3122_LR_Pano 490 22 964 71 7 221 2383 CLK3,EDC3
SE_02_099800384 chr15:74626336-74679707 Sample_02_0998 Lymphoma OCI-LY1_DMSO 384 37 1154 78 4 152 1488 CLK3,EDC3,CYP1A1
SE_02_021100357 chr15:74629510-74664995 Sample_02_0211 Lung MRC-5_NFD_1DPT 357 8 752 57 2 98 937 CLK3,EDC3
SE_01_011501203 chr15:74631168-74656029 Sample_01_0115 Skeletal Muscle myotube originated from skeletal muscle myoblast 1203 6 540 39 2 62 598 EDC3,CLK3
SE_02_069800035 chr15:74634697-74675104 Sample_02_0698 Lung NCI-H1048-cas9_sgPOU2F3 35 14 866 64 2 71 386 EDC3,CLK3
SE_02_051500118 chr15:74635395-74657967 Sample_02_0515 Esophagus KYSE140 118 13 486 34 2 24 226 EDC3,CLK3
SE_02_050300118 chr15:74635396-74657967 Sample_02_0503 Esophagus KYSE140_1 118 13 486 34 2 24 225 EDC3,CLK3
SE_02_083200745 chr15:74635412-74671687 Sample_02_0832 Umblical vein HUVECs_TNF30min 745 21 756 55 2 48 274 EDC3,CLK3
SE_02_102600464 chr15:74635516-74657649 Sample_02_1026 Esophagus KYSE200 464 15 475 34 2 19 209 EDC3,CLK3
SE_02_068400265 chr15:74635740-74664067 Sample_02_0684 Lung DMS79 265 12 601 49 2 21 176 EDC3,CLK3
SE_02_020200276 chr15:74637746-74664905 Sample_02_0202 Stomach YCC7 276 8 566 46 2 35 162 EDC3,CLK3
SE_02_074900259 chr15:74638378-74665616 Sample_02_0749 Mammary gland HCC1599_GSI 259 10 565 43 2 35 162 EDC3,CLK3
SE_02_074800587 chr15:74638483-74665269 Sample_02_0748 Mammary gland HCC1599_WO 587 9 556 43 2 35 162 EDC3,CLK3
SE_02_016900235 chr15:74638925-74666629 Sample_02_0169 Prostate LNCaP_R1881 235 4 581 43 2 35 162 EDC3,CLK3
SE_02_151100362 chr15:74639090-74664913 Sample_02_1511 Lung H3122_untreated 362 21 538 42 2 35 162 EDC3,CLK3
SE_02_140700284 chr15:74639259-74666059 Sample_02_1407 Prostate LNCaP_R1881 4h 284 6 560 42 2 35 162 EDC3,CLK3
SE_02_076400263 chr15:74639266-74666156 Sample_02_0764 Prostate LNCaP_DHT_DMSO_6h 263 6 563 43 2 35 162 EDC3,CLK3
SE_02_140900207 chr15:74639816-74666002 Sample_02_1409 Prostate LNCaP_R1881 4h_MED19_OE 207 5 548 40 2 35 162 EDC3,CLK3
SE_02_140800330 chr15:74639969-74665760 Sample_02_1408 Prostate LNCaP_EtOH_vehicle_4h_MED19_OE 330 4 541 40 2 35 162 EDC3,CLK3
SE_02_017000264 chr15:74640196-74666066 Sample_02_0170 Prostate LNCaP_R1881_DOX 264 3 541 40 2 35 162 EDC3,CLK3
SE_02_140600357 chr15:74640324-74665640 Sample_02_1406 Prostate LNCaP_EtOH_vehicle_4h 357 7 530 40 2 35 155 EDC3,CLK3
SE_02_067300496 chr15:74640425-74665614 Sample_02_0673 Prostate LNCAP_FA 496 4 529 40 2 35 143 EDC3,CLK3
SE_01_003700947 chr15:74640428-74665800 Sample_01_0037 Liver hepatocyte 947 3 534 40 2 35 143 EDC3,CLK3
SE_02_151300393 chr15:74640573-74665624 Sample_02_1513 Lung Transitional AT2->1 cells 393 4 527 40 2 31 120 EDC3,CLK3
SE_01_006800144 chr15:74640596-74645492 Sample_01_0068 Prostate: derived from metastatic site: vertebral metastasis VCaP 144 1 121 7 0 11 26 EDC3,CLK3
SE_02_151400388 chr15:74640763-74665159 Sample_02_1514 Lung Differentiated AT1-like cells 388 6 512 40 2 27 92 EDC3,CLK3
SE_01_010500605 chr15:74640838-74665393 Sample_01_0105 Thyroid gland thyroid gland_54y 605 8 514 39 2 27 91 EDC3,CLK3
SE_02_043900895 chr15:74640951-74658383 Sample_02_0439 Bone Hu09 895 7 383 24 2 10 91 EDC3,CLK3
SE_02_105100600 chr15:74640955-74664602 Sample_02_1051 Esophagus Eso26 600 5 500 39 2 27 91 EDC3,CLK3
SE_02_156900940 chr15:74641168-74665971 Sample_02_1569 Endothelial Endothelial cells 940 9 523 39 2 27 91 EDC3,CLK3
SE_02_096500578 chr15:74642336-74664669 Sample_02_0965 Brain H3.3K27M_HSJ031-C3-Rx_cells 578 8 475 38 2 26 91 EDC3,CLK3
SE_02_112200155 chr15:74644115-74665156 Sample_02_1122 Adipose visceral adipose_CS_H507 155 7 437 35 2 18 91 EDC3,CLK3
SE_02_125200624 chr15:74648594-74658306 Sample_02_1252 Bone marrow RS4_11_DMSO_10h 624 8 198 11 1 0 91 EDC3,CLK3
Genomic distribution of SEs associated with CLK3
Genome Browser

The strength of the tissue affected by the gene

Expression of CLK3

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)