SEdb 2.0
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  2. Super-enhancer search result of gene-based

Gene overview

Strategies/Algorithm: closest Ensembl ID: ENSG00000100038
Gene: TOP3B Gene type: protein_coding
Strand: - External links:
Genomic region: chr22:21957025-21982813 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_021600300 chr22:21955206-21992015 Sample_02_0216 Skin NHEK_scramble 300 9 1094 111 1 117 2215 TOP3B,PPM1F
SE_02_073100424 chr22:22000134-22038246 Sample_02_0731 Lymphoma J4_Mantle cell lymphoma tissue_THZ1 424 10 1347 120 6 0 502 PPM1F,TOP3B
SE_02_073300437 chr22:22000635-22038725 Sample_02_0733 Lymphoma L20_Mantle cell lymphoma tissue_THZ1 437 12 1343 122 6 0 502 PPM1F,TOP3B
SE_02_073000447 chr22:22000701-22042144 Sample_02_0730 Lymphoma J4_Mantle cell lymphoma tissue_DMSO 447 9 1437 129 6 0 502 PPM1F,TOP3B
SE_02_073200487 chr22:22000896-22038315 Sample_02_0732 Lymphoma L20_Mantle cell lymphoma tissue_DMSO 487 8 1324 118 6 0 502 PPM1F,TOP3B
SE_01_004000167 chr22:22005560-22062683 Sample_01_0040 Haematopoietic and lymphoid tissue Karpas-422 167 5 1940 179 7 0 599 TOP3B
SE_02_106500083 chr22:22005717-22062335 Sample_02_1065 Lymphoma KARPAS-422_DMSO_8d 83 13 1928 178 7 0 599 TOP3B
SE_02_130300228 chr22:22009146-22063236 Sample_02_1303 Lymphoma RL_tazemetostat 228 13 1863 173 6 0 599 TOP3B
SE_02_130200189 chr22:22009224-22063268 Sample_02_1302 Lymphoma RL DMSO 189 7 1864 174 6 0 599 TOP3B
SE_02_130400350 chr22:22009643-22063312 Sample_02_1304 Lymphoma RL_lenalidomide_tazemetostat 350 15 1858 175 7 0 599 TOP3B
SE_02_115200260 chr22:22009729-22061727 Sample_02_1152 Lymphoma RL_WT_gRNA1 260 7 1807 162 5 0 599 TOP3B
SE_02_115300206 chr22:22009863-22062131 Sample_02_1153 Lymphoma RL_R1446C_gRNA1 206 6 1820 168 6 0 599 TOP3B
SE_02_075100285 chr22:22010056-22061792 Sample_02_0751 Lymphoma Rec-1_WO 285 21 1801 163 5 0 599 TOP3B
SE_02_075000310 chr22:22010115-22061843 Sample_02_0750 Lymphoma Rec-1_GSI 310 17 1801 166 5 0 599 TOP3B
SE_02_072900627 chr22:22010184-22043701 Sample_02_0729 Lymphoma I10_Mantle cell lymphoma tissue_THZ1 627 14 1225 119 3 0 542 TOP3B
SE_02_115400275 chr22:22010270-22062239 Sample_02_1154 Lymphoma RL_R1446C_gRNA1_KDAC001 275 6 1811 169 6 0 599 TOP3B
SE_02_073500504 chr22:22010321-22038750 Sample_02_0735 Lymphoma PAR_Mantle cell lymphoma tissue_THZ1 504 11 1088 106 3 0 502 TOP3B
SE_02_098801017 chr22:22018126-22038935 Sample_02_0988 Blood K562_EPZ 1017 5 843 80 3 0 502 TOP3B
SE_02_088500906 chr22:22020429-22039111 Sample_02_0885 Blood NALM6_2 906 7 762 70 3 0 502 TOP3B
SE_02_021300105 chr22:22021433-22062784 Sample_02_0213 Burkitts lymphoma of the left maxilla Raji_JQ1 105 3 1469 129 6 0 599 TOP3B
SE_02_012200390 chr22:22021622-22042776 Sample_02_0122 Haematopoietic and lymphoid tissue TOLEDO 390 5 829 70 3 0 502 TOP3B
SE_02_011800228 chr22:22021850-22046834 Sample_02_0118 Haematopoietic and lymphoid tissue MINO 228 5 953 83 4 0 599 TOP3B
SE_01_009600353 chr22:22021880-22061860 Sample_01_0096 B-cell lymphoma DOHH2 353 6 1419 119 5 0 599 TOP3B
SE_02_109700312 chr22:22021969-22080742 Sample_02_1097 Haematopoietic and lymphoid tissue 697 312 34 1977 190 7 0 751 TOP3B
SE_02_077900250 chr22:22022384-22061822 Sample_02_0779 Lymphoma U2932 250 9 1397 113 5 0 599 TOP3B
SE_01_005500285 chr22:22023749-22062132 Sample_01_0055 Haematopoietic and lymphoid tissue OCI-LY7 285 6 1345 111 6 0 528 TOP3B
SE_02_011700198 chr22:22024490-22062578 Sample_02_0117 Haematopoietic and lymphoid tissue KARPAS-422 198 4 1345 110 6 0 528 TOP3B
SE_02_012100102 chr22:22024634-22062398 Sample_02_0121 Haematopoietic and lymphoid tissue SUDHL-4 102 3 1334 108 6 0 528 TOP3B
SE_01_005300178 chr22:22024840-22062131 Sample_01_0053 Haematopoietic and lymphoid tissue OCI-LY1 178 4 1316 104 6 0 528 TOP3B
SE_02_012000193 chr22:22024982-22062370 Sample_02_0120 Haematopoietic and lymphoid tissue REC-1 193 8 1320 107 6 0 528 TOP3B
SE_02_021200307 chr22:22024984-22047882 Sample_02_0212 Burkitts lymphoma of the left maxilla Raji_DMSO 307 4 871 65 4 0 528 TOP3B
SE_02_036300349 chr22:22025051-22064117 Sample_02_0363 Haematopoietic and lymphoid tissue 697 349 7 1368 114 7 0 521 TOP3B
SE_02_121800079 chr22:22025055-22063561 Sample_02_1218 Bone marrow Daudi 79 16 1351 112 7 0 520 TOP3B
SE_02_122500157 chr22:22025062-22061757 Sample_02_1225 Bone marrow RAJI 157 11 1295 96 5 0 519 TOP3B,PPM1F
SE_02_099800269 chr22:22025132-22061744 Sample_02_0998 Lymphoma OCI-LY1_DMSO 269 32 1292 96 5 0 514 TOP3B
SE_02_099900351 chr22:22025178-22062221 Sample_02_0999 Lymphoma OCI-LY1_966 351 21 1306 103 6 0 501 TOP3B
SE_02_150300260 chr22:22058275-22112700 Sample_02_1503 Brain SHEP-21N_DOX_2h_NOSPIKE 260 14 1809 203 9 0 363 TOP3B
SE_02_150200274 chr22:22058397-22112343 Sample_02_1502 Brain SHEP-21N_DOX_24h_NOSPIKE 274 23 1794 202 9 0 363 TOP3B
SE_02_150100251 chr22:22058621-22088226 Sample_02_1501 Brain SHEP-21N_NOSPIKE 251 15 912 112 5 0 219 TOP3B
SE_02_149700368 chr22:22060796-22083372 Sample_02_1497 Brain SHEP-21N 368 8 697 91 4 0 152 TOP3B
SE_02_149800442 chr22:22060818-22083245 Sample_02_1498 Brain SHEP-21N_DOX_2h 442 10 690 90 4 0 152 TOP3B
SE_02_150700470 chr22:22061006-22079253 Sample_02_1507 Brain SHEP-21N_DOX_24h 470 6 556 78 2 0 77 TOP3B
SE_01_011500872 chr22:22061166-22081544 Sample_01_0115 Skeletal Muscle myotube originated from skeletal muscle myoblast 872 3 620 82 2 0 152 TOP3B
SE_02_075001099 chr22:22096380-22119422 Sample_02_0750 Lymphoma Rec-1_GSI 1099 7 910 108 2 0 242 TOP3B
Genomic distribution of SEs associated with TOP3B
Genome Browser

The strength of the tissue affected by the gene

Expression of TOP3B

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)