SEdb 2.0
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  2. Super-enhancer search result of gene-based

Gene overview

Strategies/Algorithm: closest Ensembl ID: ENSG00000159267
Gene: HLCS Gene type: protein_coding
Strand: - External links:
Genomic region: chr21:36748626-36990236 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_127800975 chr21:36828590-36854975 Sample_02_1278 Chordoma UCH1_DMSO_48h 975 6 755 57 0 58 0 HLCS
SE_02_041200277 chr21:36828885-36867590 Sample_02_0412 Liver TTC549_Doxycycline 277 8 1088 104 2 70 0 HLCS
SE_02_127700315 chr21:36833197-36862039 Sample_02_1277 Prostate PC3_COMBO 315 12 828 75 1 50 0 HLCS
SE_02_127500316 chr21:36834806-36885452 Sample_02_1275 Prostate PC3_Vorinostat 316 19 1426 141 5 98 0 HLCS
SE_02_076200320 chr21:36837804-36929543 Sample_02_0762 Podocyte podocyte_CTL 320 23 2583 218 11 208 70 HLCS
SE_02_071201085 chr21:36845238-36862804 Sample_02_0712 Pancreas BxPC3_sgNEG 1085 4 497 46 1 30 0 HLCS
SE_02_071301247 chr21:36845414-36863999 Sample_02_0713 Pancreas BxPC3_sgTP63 1247 8 510 52 1 30 0 HLCS
SE_02_048102096 chr21:36846051-36876239 Sample_02_0481 Mammary gland MDA-MB231 2096 10 822 99 3 66 0 HLCS
SE_02_087800981 chr21:36846306-36865972 Sample_02_0878 Ovary SVOG3e cells_noDox_control 981 4 540 61 1 42 0 HLCS
SE_02_070700646 chr21:36846319-36862858 Sample_02_0707 Pancreas BxPC3 WT 646 4 459 45 1 30 0 HLCS
SE_02_043800322 chr21:36846333-36890683 Sample_02_0438 Bone HOS 322 23 1232 125 6 111 0 HLCS
SE_02_088101227 chr21:36846348-36862606 Sample_02_0881 Ovary SVOG3e cells_Dox_12h_transduced_V5-FOXL2_WT 1227 4 451 44 1 30 0 HLCS
SE_02_087901209 chr21:36846619-36865783 Sample_02_0879 Ovary SVOG3e cells_Dox_12h_control 1209 6 532 60 1 34 0 HLCS
SE_02_088301317 chr21:36846620-36867584 Sample_02_0883 Ovary SVOG3e_cells_Dox_12h_transduced with V5-FOXL2 C134W 1317 9 575 67 2 48 0 HLCS
SE_02_088001015 chr21:36846645-36865851 Sample_02_0880 Ovary SVOG3e cells_noDox_transduced_V5-FOXL2_WT 1015 4 532 60 1 35 0 HLCS
SE_02_127600395 chr21:36846666-36885064 Sample_02_1276 Prostate PC3_GSK126 395 14 1057 114 5 78 0 HLCS
SE_02_088201270 chr21:36846755-36874074 Sample_02_0882 Ovary SVOG3e_cells_noDox_transduced with V5-FOXL2 C134W 1270 5 750 92 3 66 0 HLCS
SE_02_137901163 chr21:36846795-36862504 Sample_02_1379 Pancreas Pancreatic_tumor_associated_fibroblasts_PS1_untreated 1163 5 442 44 1 30 0 HLCS
SE_02_038000132 chr21:36849329-36927732 Sample_02_0380 Skeletal muscle RH18 132 14 2210 186 11 171 70 HLCS
SE_02_114900599 chr21:36858622-36884731 Sample_02_1149 Kidney WT 9-12_control_Nrf2_SFN 599 5 716 80 5 53 0 HLCS
SE_02_106700106 chr21:36859002-36912244 Sample_02_1067 Bone SJSA-1 106 18 1495 122 10 99 70 HLCS
SE_02_003000182 chr21:36860436-36874441 Sample_02_0030 Kidney human kidney proximal tubule cells 182 5 368 51 2 41 0 HLCS
SE_02_047400414 chr21:36881625-36927495 Sample_02_0474 Fibroblast umbilical cord Fibroblast 414 7 1333 81 6 104 70 HLCS
SE_02_127300110 chr21:36881854-36930226 Sample_02_1273 Cervix HeLa 110 13 1396 88 7 128 88 HLCS
SE_02_143301578 chr21:36888767-36923269 Sample_02_1433 Bone A673 STAG2 null 1578 12 987 54 5 45 70 HLCS
SE_02_058900387 chr21:36900656-36917729 Sample_02_0589 Cervix HeLa Kyoto_Luci siRNA 387 8 475 30 2 18 0 HLCS
SE_02_017200537 chr21:36902381-36930107 Sample_02_0172 Lung IMR-90_quiescent 537 3 766 59 4 82 7 HLCS
SE_02_017100420 chr21:36902394-36930029 Sample_02_0171 Lung IMR-90_proliferating 420 4 764 59 4 82 0 HLCS
SE_02_111000363 chr21:36903789-36930524 Sample_02_1110 Other HGrC1 363 11 741 55 3 85 45 HLCS
SE_02_043800549 chr21:36906418-36927414 Sample_02_0438 Bone HOS 549 10 583 40 2 58 0 HLCS
SE_02_088300770 chr21:36906639-36940045 Sample_02_0883 Ovary SVOG3e_cells_Dox_12h_transduced with V5-FOXL2 C134W 770 5 935 69 6 137 331 HLCS
SE_02_088100810 chr21:36906804-36917676 Sample_02_0881 Ovary SVOG3e cells_Dox_12h_transduced_V5-FOXL2_WT 810 3 296 16 1 17 0 HLCS
SE_02_137801165 chr21:36906882-36928391 Sample_02_1378 Pancreas Pancreatic_tumor_associated_fibroblasts_CAF08_untreated 1165 10 600 43 2 75 0 HLCS
SE_02_116200809 chr21:36906930-36927363 Sample_02_1162 Stomach YCC11 809 9 567 40 2 58 0 HLCS
SE_02_147500890 chr21:36906981-36930402 Sample_02_1475 Bone CHLA-25 890 9 645 49 3 85 34 HLCS
SE_02_058800417 chr21:36907098-36926311 Sample_02_0588 Cervix HeLa Kyoto_untreated 417 11 530 36 2 58 0 HLCS
SE_02_088000654 chr21:36907186-36917458 Sample_02_0880 Ovary SVOG3e cells_noDox_transduced_V5-FOXL2_WT 654 3 275 16 1 17 0 HLCS
SE_02_127500291 chr21:36907224-36929377 Sample_02_1275 Prostate PC3_Vorinostat 291 15 610 46 2 78 0 HLCS
SE_02_087800757 chr21:36907259-36917742 Sample_02_0878 Ovary SVOG3e cells_noDox_control 757 4 282 16 1 18 0 HLCS
SE_01_005800621 chr21:36907284-36930131 Sample_01_0058 Prostate PC-3 621 3 625 48 3 82 7 HLCS
SE_02_088200653 chr21:36907313-36940121 Sample_02_0882 Ovary SVOG3e_cells_noDox_transduced with V5-FOXL2 C134W 653 6 919 69 6 137 331 HLCS
SE_02_124000552 chr21:36907349-36928768 Sample_02_1240 Skin MCC13_virus_negative 552 9 593 44 2 75 0 HLCS
SE_02_026801141 chr21:36907353-36912305 Sample_02_0268 Kidney A-498 1141 2 128 9 1 10 0 HLCS
SE_02_001001055 chr21:36907422-36912333 Sample_02_0010 Kidney A-498_emptyvector 1055 1 127 9 1 10 0 HLCS
SE_02_087900965 chr21:36907551-36928522 Sample_02_0879 Ovary SVOG3e cells_Dox_12h_control 965 3 588 44 2 75 0 HLCS
SE_02_045100978 chr21:36907800-36928597 Sample_02_0451 Skin in vitro transformedskin fibroblasts_tumourigenic 978 5 580 43 2 75 0 HLCS
SE_02_137400811 chr21:36907896-36917645 Sample_02_1374 Pancreas Pancreatic_tumor_associated_fibroblasts_B009B_untreated 811 5 266 15 1 17 0 HLCS
SE_02_047500578 chr21:36907976-36921401 Sample_02_0475 Induced hepatocyte-like cells hepatocyte-like cells 578 7 367 21 2 34 0 HLCS
SE_02_059000790 chr21:36907993-36917763 Sample_02_0590 Cervix HeLa Kyoto_Luci PWWP2A siRNA 790 6 268 15 1 20 0 HLCS
SE_02_137900508 chr21:36908045-36929319 Sample_02_1379 Pancreas Pancreatic_tumor_associated_fibroblasts_PS1_untreated 508 5 591 44 2 78 0 HLCS
SE_02_137701178 chr21:36908046-36928156 Sample_02_1377 Pancreas Pancreatic_tumor_associated_fibroblasts_BF1_untreated 1178 5 566 42 2 73 0 HLCS
SE_02_044800557 chr21:36908066-36929771 Sample_02_0448 Bone MNNG 557 6 597 45 2 81 0 HLCS
SE_02_147200720 chr21:36908112-36912107 Sample_02_1472 Fetal lung IMR-90 720 2 113 7 1 10 0 HLCS
SE_02_019600241 chr21:36908234-36911327 Sample_02_0196 Stomach NCC59 241 2 91 6 1 10 0 HLCS
SE_02_001101084 chr21:36908248-36912935 Sample_02_0011 Kidney A-498_wtVHL 1084 2 126 9 1 10 0 HLCS
SE_02_127700126 chr21:36908683-36929795 Sample_02_1277 Prostate PC3_COMBO 126 14 584 44 2 81 0 HLCS
SE_02_129600339 chr21:36910127-36936048 Sample_02_1296 Perigastric lymph node Perigastric lymph node 339 14 727 59 4 92 62 HLCS
SE_02_104300633 chr21:36910728-37003143 Sample_02_1043 Peripheral blood Peripheral blood cells_CTCL1200 633 24 2636 374 8 176 1095 HLCS,RIPPLY3
SE_01_006800362 chr21:36922923-36936274 Sample_01_0068 Prostate: derived from metastatic site: vertebral metastasis VCaP 362 3 377 40 4 66 63 HLCS
SE_02_103600950 chr21:36957822-36978446 Sample_02_1036 Mammary gland HCC70_XY018 950 5 578 122 2 26 250 HLCS,RIPPLY3
SE_02_098800663 chr21:36962085-36975789 Sample_02_0988 Blood K562_EPZ 663 4 363 81 1 21 225 HLCS,RIPPLY3
SE_02_042400587 chr21:36964479-36991794 Sample_02_0424 Colon SW620 587 3 751 172 2 30 471 HLCS,DSCR6
SE_02_003200767 chr21:36965348-37011334 Sample_02_0032 Pancreas pancreatic-islets-M 767 11 1313 238 2 56 871 DSCR6,HLCS
SE_02_104901709 chr21:36969658-37010320 Sample_02_1049 Peripheral blood CD4+ cell_ROMI 1709 19 1173 210 2 39 673 RIPPLY3,HLCS
SE_02_104603232 chr21:36974043-37010835 Sample_02_1046 Peripheral blood CD4+ cells_CTCL1145 3232 8 1067 182 2 39 673 RIPPLY3,HLCS
SE_02_104701714 chr21:36974108-37010471 Sample_02_1047 Peripheral blood CD4+ cells_CTCL1181 1714 10 1056 179 2 39 673 RIPPLY3,HLCS
SE_02_124800704 chr21:36977636-36991024 Sample_02_1248 Bladder RT4 704 2 374 82 2 9 273 HLCS,RIPPLY3
Genomic distribution of SEs associated with HLCS
Genome Browser

The strength of the tissue affected by the gene

Expression of HLCS

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)