SEdb 2.0
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  2. Super-enhancer search result of gene-based

Gene overview

Strategies/Algorithm: closest Ensembl ID: ENSG00000168621
Gene: GDNF Gene type: protein_coding
Strand: - External links:
Genomic region: chr5:37812677-37840041 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_048101177 chr5:37656952-37674294 Sample_02_0481 Mammary gland MDA-MB231 1177 7 434 35 1 69 0 WDR70,GDNF,GDNF-AS1
SE_02_157900451 chr5:37658562-37698057 Sample_02_1579 Renal 786-M1A 451 7 1082 87 2 75 59 WDR70,GDNF
SE_02_026700555 chr5:37662226-37697941 Sample_02_0267 Kidney 786-O 555 5 991 75 2 75 50 WDR70,GDNF
SE_02_111500994 chr5:37664197-37670285 Sample_02_1115 Liver HepG2 994 3 155 10 0 61 0 WDR70,GDNF
SE_02_111300778 chr5:37664300-37670534 Sample_02_1113 Bone U2OS 778 2 170 12 0 61 0 WDR70,GDNF
SE_02_046900492 chr5:37667878-37672742 Sample_02_0469 Kidney 786-O PBRM1 shRNA#2 492 4 130 11 1 25 0 WDR70,GDNF
SE_02_048100365 chr5:37694874-37742271 Sample_02_0481 Mammary gland MDA-MB231 365 11 1087 56 4 192 298 WDR70,GDNF,GDNF-AS1
SE_02_126300603 chr5:37695556-37741257 Sample_02_1263 Bone Im-GCT-4072_G34W unedited 603 9 1041 54 4 192 298 WDR70,GDNF,GDNF-AS1
SE_02_011000969 chr5:37695826-37741922 Sample_02_0110 Ovaries IOE11 969 5 1065 55 4 192 298 WDR70,GDNF
SE_02_017300919 chr5:37696220-37739570 Sample_02_0173 Lung IMR-90_senescent 919 10 989 50 3 183 298 WDR70,GDNF
SE_02_017000232 chr5:37703260-37756973 Sample_02_0170 Prostate LNCaP_R1881_DOX 232 7 1278 69 4 200 234 WDR70,GDNF
SE_02_063000305 chr5:37708553-37723371 Sample_02_0630 Gastrointestinal Stromal GIST-T1_Imatinib 305 4 307 19 1 106 95 WDR70,GDNF
SE_02_062900246 chr5:37708695-37721602 Sample_02_0629 Gastrointestinal Stromal GIST-T1_DMSO 246 4 267 16 1 96 58 WDR70,GDNF
SE_02_154200091 chr5:37708727-37723416 Sample_02_1542 Gastrointestinal Stromal GIST-T1 91 5 304 17 1 104 95 WDR70,GDNF
SE_02_063100230 chr5:37708736-37721509 Sample_02_0631 Gastrointestinal Stromal GIST-T1_JQ1 230 3 266 16 1 96 58 WDR70,GDNF
SE_02_154500120 chr5:37709608-37721518 Sample_02_1545 Gastrointestinal Stromal GIST-T1/816 120 5 249 13 1 78 58 WDR70,GDNF
SE_02_030100537 chr5:37710846-37777761 Sample_02_0301 Neuroblastoma GIMEN 537 8 1639 94 6 235 232 WDR70,GDNF
SE_02_158400391 chr5:37710876-37742032 Sample_02_1584 Brain U87 GBM_Mock 391 4 706 33 2 155 192 WDR70,GDNF
SE_02_076900907 chr5:37710903-37738986 Sample_02_0769 Ovary HEYA8 907 16 630 30 2 145 192 WDR70,GDNF
SE_02_137700839 chr5:37710956-37741264 Sample_02_1377 Pancreas Pancreatic_tumor_associated_fibroblasts_BF1_untreated 839 12 676 32 2 155 192 WDR70,GDNF
SE_02_056900202 chr5:37711012-37790382 Sample_02_0569 Periodontal ligament mesenchymal stem cell 202 28 2040 123 9 243 232 WDR70,GDNF
SE_02_060900047 chr5:37711176-37819093 Sample_02_0609 Liposarcoma LPS141 47 26 2891 168 13 345 754 GDNF,WDR70,GDNF-AS1
SE_02_132000740 chr5:37711198-37739216 Sample_02_1320 Connective Tissue HT1080_EWS-FLI1 740 8 629 30 2 146 192 WDR70,GDNF
SE_02_127900330 chr5:37711318-37752249 Sample_02_1279 Bone Mesenchymal stem cells 330 5 975 49 3 160 192 WDR70,GDNF
SE_02_157900543 chr5:37711355-37738862 Sample_02_1579 Renal 786-M1A 543 5 613 30 2 145 192 WDR70,GDNF
SE_02_137800382 chr5:37711466-37751851 Sample_02_1378 Pancreas Pancreatic_tumor_associated_fibroblasts_CAF08_untreated 382 11 951 49 3 158 192 WDR70,GDNF
SE_02_063800516 chr5:37714434-37752250 Sample_02_0638 Fibroblast HGPS fibroblast_LMNA_AG11498 516 11 895 41 3 151 192 WDR70,GDNF
SE_02_043800426 chr5:37714455-37751286 Sample_02_0438 Bone HOS 426 13 862 38 3 149 192 WDR70,GDNF
SE_02_086700238 chr5:37714527-37784902 Sample_02_0867 Bone marrow Bone marrow derived hMSC_d0 238 32 1775 104 8 226 232 WDR70,GDNF
SE_02_156600436 chr5:37714542-37753954 Sample_02_1566 Dermal Dermal fibroblast 436 12 922 45 4 167 232 WDR70,GDNF
SE_02_063700622 chr5:37714560-37751345 Sample_02_0637 Fibroblast fibroblast_WT_GM07492 622 14 862 38 3 149 192 WDR70,GDNF
SE_02_011200430 chr5:37715089-37739711 Sample_02_0112 Connective tissue HT1080_untreated 430 2 549 23 2 133 192 WDR70,GDNF
SE_02_127100631 chr5:37715205-37741511 Sample_02_1271 Leiomyosarcoma SK-LMS-1_WT 631 7 588 25 2 142 192 WDR70,GDNF
SE_02_141800322 chr5:37715267-37725286 Sample_02_1418 Brain SF9427 322 2 208 7 1 86 147 WDR70,GDNF
SE_02_113900607 chr5:37715274-37741197 Sample_02_1139 Retinal Pigmented Epithelial RPE1-anaphase/telophase 607 5 575 24 2 142 192 WDR70,GDNF
SE_02_113800812 chr5:37715280-37741580 Sample_02_1138 Retinal Pigmented Epithelial RPE1-prometaphase 812 6 587 25 2 142 192 WDR70,GDNF
SE_02_113700636 chr5:37715594-37741388 Sample_02_1137 Retinal Pigmented Epithelial RPE1-interphase 636 6 572 24 2 142 192 WDR70,GDNF
SE_02_108500540 chr5:37715717-37741518 Sample_02_1085 Retinal Pigmented Epithelial hTERT-RPE1 540 5 578 25 2 142 192 WDR70,GDNF
SE_02_076200610 chr5:37715775-37752102 Sample_02_0762 Podocyte podocyte_CTL 610 3 867 41 3 147 192 WDR70,GDNF
SE_02_011300376 chr5:37716154-37724576 Sample_02_0113 Connective tissue HT1080_DOX5d 376 2 177 7 0 72 95 WDR70,GDNF
SE_02_081100626 chr5:37716648-37752466 Sample_02_0811 Thyroid BCPAP 626 8 861 43 2 148 201 WDR70,GDNF
SE_02_105900976 chr5:37716787-37739084 Sample_02_1059 Bone A673_WT 976 8 501 22 1 130 192 WDR70,GDNF
SE_02_147300980 chr5:37716787-37739084 Sample_02_1473 Bone A-673 980 8 501 22 1 130 192 WDR70,GDNF
SE_02_076300931 chr5:37716842-37752096 Sample_02_0763 Podocyte podocyte_DEX 931 6 844 41 2 145 192 WDR70,GDNF
SE_01_005600724 chr5:37716867-37751998 Sample_01_0056 Bone osteoblast 724 5 842 41 2 142 192 WDR70,GDNF
SE_02_156800989 chr5:37716957-37740934 Sample_02_1568 Heart Cardiac progenitor cells 989 5 539 24 1 139 192 WDR70,GDNF
SE_02_026500659 chr5:37717002-37742079 Sample_02_0265 Skeletal muscle 7250-PAX3-FOXO1 659 6 574 25 1 139 192 WDR70,GDNF
SE_02_157100398 chr5:37717082-37752335 Sample_02_1571 Fibroblast Fibroblast cells 398 7 852 42 2 146 193 WDR70,GDNF
SE_02_152200752 chr5:37717150-37741381 Sample_02_1522 Skin A375 RTKi 752 3 542 24 1 139 192 WDR70,GDNF
SE_02_061001355 chr5:37717233-37725521 Sample_02_0610 Liposarcoma MLS 1765-92 1355 3 179 7 0 84 147 WDR70,GDNF
SE_02_113300632 chr5:37717242-37741813 Sample_02_1133 Liver Hepatic stellate cells 632 6 563 25 1 139 192 WDR70,GDNF
SE_02_124100575 chr5:37717264-37741338 Sample_02_1241 Skin MCC26_virus_negative 575 8 540 24 1 139 192 WDR70,GDNF
SE_02_074100690 chr5:37717329-37741605 Sample_02_0741 Muscle RH30 690 10 549 25 1 139 192 WDR70,GDNF
SE_02_140700452 chr5:37717352-37756893 Sample_02_1407 Prostate LNCaP_R1881 4h 452 9 963 48 3 162 232 WDR70,GDNF
SE_02_131100173 chr5:37717511-37778034 Sample_02_1311 Bone marrow HDMSCs 173 7 1503 86 6 219 232 WDR70,GDNF
SE_02_046900481 chr5:37718083-37724508 Sample_02_0469 Kidney 786-O PBRM1 shRNA#2 481 5 134 7 0 34 95 WDR70,GDNF
SE_02_095100290 chr5:37719601-37752739 Sample_02_0951 HMSCs hMSCs 290 10 809 42 2 107 227 WDR70,GDNF
SE_02_131000318 chr5:37720743-37778106 Sample_02_1310 Bone marrow ASMSCs 318 7 1442 84 6 166 232 WDR70,GDNF
SE_02_051100323 chr5:37737140-37741300 Sample_02_0511 Prostate LNCaP95_shARv7_ETOH 323 1 78 3 0 26 0 WDR70,GDNF
SE_02_050900297 chr5:37737378-37740927 Sample_02_0509 Prostate LNCaP95_shGFP_ETOH 297 1 69 3 0 24 0 WDR70,GDNF
SE_02_051000330 chr5:37737436-37741236 Sample_02_0510 Prostate LNCaP95_shGFP_DHT 330 1 74 3 0 24 0 WDR70,GDNF
SE_02_003000445 chr5:37737680-37741248 Sample_02_0030 Kidney human kidney proximal tubule cells 445 1 66 3 0 23 0 WDR70,GDNF
SE_02_051200158 chr5:37737859-37740789 Sample_02_0512 Prostate LNCaP95_shARv7_DHT 158 4 58 3 0 23 0 WDR70,GDNF
SE_01_011500578 chr5:37767085-37777851 Sample_01_0115 Skeletal Muscle myotube originated from skeletal muscle myoblast 578 4 286 23 2 57 0 GDNF
SE_02_028100443 chr5:37767816-37778179 Sample_02_0281 Bone U2OS 443 1 283 23 3 55 0 GDNF,NUP155
SE_02_139800673 chr5:37767901-37786194 Sample_02_1398 Bone U2OS_siNC 673 8 540 46 4 55 0 GDNF
SE_02_048102115 chr5:37768149-37774951 Sample_02_0481 Mammary gland MDA-MB231 2115 3 165 13 1 34 0 GDNF,GDNF-AS1
SE_02_111500436 chr5:37768295-37793083 Sample_02_1115 Liver HepG2 436 7 757 58 6 57 0 GDNF,GDNF-AS1
SE_02_076201009 chr5:37768318-37794489 Sample_02_0762 Podocyte podocyte_CTL 1009 6 800 59 6 57 0 GDNF,GDNF-AS1
SE_02_113400260 chr5:37768775-37778085 Sample_02_1134 Bone U2OS-interphase 260 6 262 22 3 43 0 GDNF,GDNF-AS1
SE_02_026500189 chr5:37768833-37818611 Sample_02_0265 Skeletal muscle 7250-PAX3-FOXO1 189 5 1495 93 9 153 522 GDNF
SE_02_114900597 chr5:37768919-37794574 Sample_02_1149 Kidney WT 9-12_control_Nrf2_SFN 597 5 797 59 6 51 0 GDNF,GDNF-AS1
SE_02_006900732 chr5:37768959-37774090 Sample_02_0069 Brain SF268 732 1 132 9 1 24 0 GDNF
SE_02_043800257 chr5:37769036-37794596 Sample_02_0438 Bone HOS 257 10 794 59 6 51 0 GDNF,GDNF-AS1
SE_02_157900161 chr5:37769090-37816460 Sample_02_1579 Renal 786-M1A 161 15 1429 89 9 153 522 GDNF,GDNF-AS1
SE_02_111000580 chr5:37769099-37777817 Sample_02_1110 Other HGrC1 580 6 240 22 2 43 0 GDNF
SE_02_111300206 chr5:37769147-37793046 Sample_02_1113 Bone U2OS 206 7 739 58 6 51 0 GDNF,GDNF-AS1
SE_02_113701306 chr5:37769165-37774168 Sample_02_1137 Retinal Pigmented Epithelial RPE1-interphase 1306 2 127 10 1 24 0 GDNF
SE_02_061000365 chr5:37769236-37794679 Sample_02_0610 Liposarcoma MLS 1765-92 365 7 792 59 6 51 0 GDNF,GDNF-AS1
SE_02_046700198 chr5:37769470-37772907 Sample_02_0467 Kidney 786-O_control 198 8 89 7 1 24 0 GDNF
SE_02_156600873 chr5:37769531-37793459 Sample_02_1566 Dermal Dermal fibroblast 873 8 734 58 6 51 0 GDNF,GDNF-AS1
SE_02_026400849 chr5:37769531-37793820 Sample_02_0264 Skeletal muscle 7250-empty 849 4 745 59 6 51 0 GDNF
SE_02_127901707 chr5:37769593-37793977 Sample_02_1279 Bone Mesenchymal stem cells 1707 6 750 59 6 51 0 GDNF,GDNF-AS1
SE_02_087801359 chr5:37769701-37774965 Sample_02_0878 Ovary SVOG3e cells_noDox_control 1359 2 128 13 1 24 0 GDNF
SE_02_157100312 chr5:37769703-37787828 Sample_02_1571 Fibroblast Fibroblast cells 312 4 545 46 4 44 0 GDNF
SE_02_074100913 chr5:37769788-37774004 Sample_02_0741 Muscle RH30 913 2 103 8 1 24 0 GDNF
SE_02_087901434 chr5:37769797-37774440 Sample_02_0879 Ovary SVOG3e cells_Dox_12h_control 1434 1 108 10 1 24 0 GDNF
SE_02_093600687 chr5:37769821-37774096 Sample_02_0936 Retinal Pigmented Epithelial RPE188_TnT 687 2 104 9 1 24 0 GDNF
SE_02_093800832 chr5:37769828-37774134 Sample_02_0938 Retinal Pigmented Epithelial RPE190_TnT 832 1 107 10 1 24 0 GDNF
SE_02_088201186 chr5:37769873-37777057 Sample_02_0882 Ovary SVOG3e_cells_noDox_transduced with V5-FOXL2 C134W 1186 2 190 20 2 42 0 GDNF
SE_02_081100597 chr5:37770046-37815790 Sample_02_0811 Thyroid BCPAP 597 14 1386 89 9 133 462 GDNF,GDNF-AS1
SE_02_046900501 chr5:37770310-37773058 Sample_02_0469 Kidney 786-O PBRM1 shRNA#2 501 4 73 7 1 24 0 GDNF
SE_02_022900303 chr5:37770612-37778061 Sample_02_0229 Umbilical cord ID01 303 7 215 22 3 43 0 GDNF
SE_02_016100366 chr5:37771002-37793230 Sample_02_0161 Brain U87 366 5 696 58 6 44 0 GDNF
SE_02_122300441 chr5:37797769-37812231 Sample_02_1223 Bone marrow KMS28BM 441 4 420 27 1 27 0 GDNF,GDNF-AS1
SE_02_155500114 chr5:37801644-37858160 Sample_02_1555 Gastrointestinal Stromal GIST-4_KIT e9 114 10 1478 68 9 297 1149 GDNF-AS1,GDNF
SE_02_056900338 chr5:37802948-37850295 Sample_02_0569 Periodontal ligament mesenchymal stem cell 338 23 1220 62 8 285 1149 GDNF-AS1,GDNF
SE_02_105901115 chr5:37803571-37841167 Sample_02_1059 Bone A673_WT 1115 8 965 57 7 234 1149 GDNF-AS1,GDNF
SE_02_147301120 chr5:37803571-37841167 Sample_02_1473 Bone A-673 1120 8 965 57 7 234 1149 GDNF-AS1,GDNF
SE_02_143200923 chr5:37806141-37847962 Sample_02_1432 Bone A673 STAG2 WT 923 18 1066 53 6 262 1149 GDNF-AS1,GDNF
SE_02_076200534 chr5:37808036-37852046 Sample_02_0762 Podocyte podocyte_CTL 534 12 1139 49 7 266 1149 GDNF-AS1,GDNF
SE_02_043800181 chr5:37808060-37841676 Sample_02_0438 Bone HOS 181 13 863 45 6 226 1149 GDNF-AS1,GDNF
SE_02_086700470 chr5:37808138-37849687 Sample_02_0867 Bone marrow Bone marrow derived hMSC_d0 470 17 1065 49 7 264 1149 GDNF-AS1,GDNF
SE_02_141600672 chr5:37808255-37848748 Sample_02_1416 Brain SF9402 672 10 1033 49 6 260 1149 GDNF-AS1,GDNF
SE_02_111100229 chr5:37808367-37841721 Sample_02_1111 Other HGrC1_SMAD2/3KO 229 16 848 45 6 226 1149 GDNF-AS1,GDNF
SE_02_156600587 chr5:37808782-37848531 Sample_02_1566 Dermal Dermal fibroblast 587 16 1014 48 6 260 1149 GDNF-AS1,GDNF
SE_02_127901146 chr5:37808975-37848618 Sample_02_1279 Bone Mesenchymal stem cells 1146 7 1008 48 6 260 1149 GDNF-AS1,GDNF
SE_02_070100136 chr5:37809697-37847992 Sample_02_0701 Bone David_TC32 136 13 967 46 6 258 1149 GDNF-AS1,GDNF
SE_02_155300418 chr5:37810211-37852052 Sample_02_1553 Gastrointestinal Stromal GIST-2_KIT e11 418 12 1067 45 7 265 1149 GDNF-AS1,GDNF
SE_02_118500791 chr5:37810522-37841268 Sample_02_1185 Brain GBM14 791 8 770 41 6 210 1149 GDNF-AS1,GDNF
SE_02_143301599 chr5:37811026-37840810 Sample_02_1433 Bone A673 STAG2 null 1599 8 746 41 6 205 1149 GDNF-AS1,GDNF
SE_02_156500164 chr5:37821873-37844368 Sample_02_1565 Gastrointestinal Stromal Gastrointestinal stromal tumor 164 4 551 26 2 158 627 GDNF-AS1,GDNF
SE_02_043600507 chr5:37825865-37848627 Sample_02_0436 Kidney HEK293A_empty-vector_DMSO_6h 507 3 577 23 2 151 571 GDNF
SE_02_155400691 chr5:37831577-37841682 Sample_02_1554 Gastrointestinal Stromal GIST-3_KIT e11 691 3 254 13 2 108 571 GDNF-AS1,GDNF
SE_02_063000416 chr5:37831617-37841542 Sample_02_0630 Gastrointestinal Stromal GIST-T1_Imatinib 416 3 250 13 2 108 571 GDNF-AS1,GDNF
SE_02_062900546 chr5:37832500-37841231 Sample_02_0629 Gastrointestinal Stromal GIST-T1_DMSO 546 2 222 13 2 89 571 GDNF-AS1,GDNF
SE_02_155900693 chr5:37832505-37841143 Sample_02_1559 Gastrointestinal Stromal GIST-8_PDGFRA e18 693 2 220 13 2 89 571 GDNF-AS1,GDNF
SE_02_026500533 chr5:37833505-37848586 Sample_02_0265 Skeletal muscle 7250-PAX3-FOXO1 533 2 382 13 0 132 571 GDNF
SE_02_037200145 chr5:37833590-37848605 Sample_02_0372 Skeletal muscle RMS008 145 2 379 12 0 132 571 GDNF
SE_02_095800224 chr5:37835963-37841643 Sample_02_0958 Brain H3.3K27M_Tumor_BT245-X0-2-Rx_xenograft 224 1 137 6 0 72 258 GDNF-AS1,GDNF
SE_02_114800172 chr5:37836303-37840713 Sample_02_1148 Kidney WT 9-12_control_vehicle 172 1 111 6 0 53 238 GDNF-AS1,GDNF
SE_02_122000691 chr5:37836435-37841297 Sample_02_1220 Bone marrow JJN3 691 1 117 6 0 57 248 GDNF-AS1,GDNF
SE_02_033000954 chr5:37836471-37850091 Sample_02_0330 Endoderm MHG 954 3 347 10 1 107 248 GDNF
SE_02_114900546 chr5:37836489-37840623 Sample_02_1149 Kidney WT 9-12_control_Nrf2_SFN 546 1 106 6 0 37 227 GDNF-AS1,GDNF
Genomic distribution of SEs associated with GDNF
Genome Browser

The strength of the tissue affected by the gene

Expression of GDNF

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)