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Gene overview

Strategies/Algorithm: closest Ensembl ID: ENSG00000135414
Gene: GDF11 Gene type: protein_coding
Strand: + External links:
Genomic region: chr12:55743122-55757264 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_155300367 chr12:55722400-55765956 Sample_02_1553 Gastrointestinal Stromal GIST-2_KIT e11 367 16 945 48 1 280 2509 GDF11,CD63,BLOC1S1-RDH5,SARNP,RDH5,BLOC1S1,ITGA7,METTL7B
SE_02_149200485 chr12:55722705-55759759 Sample_02_1492 Peripheral blood CD34+ derived peripheral blood-derived mast cells 485 10 800 42 1 276 2427 GDF11,CD63,BLOC1S1-RDH5,SARNP,RDH5,BLOC1S1,ITGA7,METTL7B
SE_02_104700697 chr12:55723835-55796704 Sample_02_1047 Peripheral blood CD4+ cells_CTCL1181 697 22 1649 79 2 302 2773 GDF11,CD63,BLOC1S1-RDH5,SARNP,RDH5,BLOC1S1,DNAJC14,ORMDL2,ITGA7,TMEM198B,METTL7B,MMP19
SE_01_002100227 chr12:55724707-55747847 Sample_01_0021 Skin bipolar-neuron 227 4 507 31 0 175 1337 GDF11,CD63,RDH5,METTL7B,ITGA7,BLOC1S1
SE_02_122900862 chr12:55724924-55762907 Sample_02_1229 Haematopoietic and lymphoid tissue bone marrow K562_Control 862 14 817 42 1 277 2193 GDF11,CD63,SARNP,BLOC1S1,RDH5,ITGA7,METTL7B,RAB5B,ORMDL2,CDK2,ZC3H10,SUOX,ESYT1,WIBG,PA2G4,PMEL
SE_02_074400126 chr12:55725089-55757998 Sample_02_0744 Embryo ES derived cardiac mesoderm_day5 126 8 702 37 1 273 2154 GDF11,CD63,SARNP,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_104801065 chr12:55725681-55774178 Sample_02_1048 Peripheral blood CD4+ cell_UNTREATED 1065 10 1060 55 1 280 2122 GDF11,CD63,SARNP,BLOC1S1,RDH5,ORMDL2,ITGA7,METTL7B
SE_02_074600303 chr12:55725709-55773078 Sample_02_0746 Embryo ES derived primitive cardiomyocite_day15 303 20 1041 55 1 280 2118 GDF11,CD63,SARNP,BLOC1S1,RDH5,ORMDL2,ITGA7,METTL7B
SE_02_156000565 chr12:55726416-55760134 Sample_02_1560 Gastrointestinal Stromal GIST-9_PDGFRA e18 565 7 722 38 1 269 1941 GDF11,CD63,SARNP,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_109900733 chr12:55726480-55746610 Sample_02_1099 Haematopoietic and lymphoid tissue bone marrow K562_DMSO_noIFNG 733 4 437 28 0 171 1081 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B,RAB5B,ORMDL2,CDK2,ZC3H10,SUOX,ESYT1,WIBG,PA2G4,PMEL,SARNP
SE_00_000300742 chr12:55726490-55746885 Sample_00_0003 Adrenal gland adrenal-gland_97d 742 5 442 30 0 171 1081 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_01_003700461 chr12:55726526-55746599 Sample_01_0037 Liver hepatocyte 461 3 436 28 0 171 1078 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_110900549 chr12:55726604-55749028 Sample_02_1109 Brain SK-N-FI 549 5 483 30 0 197 1197 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_123500171 chr12:55726651-55747649 Sample_02_1235 Brain Neuroblastoma PDX tumour cells 171 7 455 29 0 171 1061 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_096700298 chr12:55726799-55757953 Sample_02_0967 Brain H3.3K27M_JN57 298 6 654 34 1 265 1890 GDF11,CD63,SARNP,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_083501035 chr12:55726841-55746766 Sample_02_0835 Bone marrow TEX-HIST1H3H-K27M-Rx_cells 1035 3 424 26 0 167 1032 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_110400547 chr12:55726851-55749079 Sample_02_1104 Brain NB-69 547 6 475 27 0 193 1170 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_017600788 chr12:55726889-55747906 Sample_02_0176 Peripheral blood LOUCY 788 3 451 27 0 166 1020 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_027500269 chr12:55726898-55746812 Sample_02_0275 Retina FW14 269 3 423 27 0 166 1019 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_092300573 chr12:55726986-55748406 Sample_02_0923 Heart fetal heart_PCW10_12522 573 5 455 26 0 164 1023 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B,RP11-644F5.10
SE_02_030400252 chr12:55727014-55749167 Sample_02_0304 Neuroblastoma N206 252 3 469 26 0 193 1162 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_155400319 chr12:55727046-55760814 Sample_02_1554 Gastrointestinal Stromal GIST-3_KIT e11 319 10 712 34 1 264 1889 GDF11,CD63,SARNP,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_118100210 chr12:55727048-55758157 Sample_02_1181 Brain GBM10 210 5 647 32 1 262 1850 GDF11,CD63,SARNP,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_092500857 chr12:55727064-55746736 Sample_02_0925 Heart fetal heart_PCW17_12570 857 3 412 25 0 164 995 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B,RP11-644F5.10
SE_02_031300215 chr12:55727068-55747470 Sample_02_0313 Neuroblastoma SK-N-DZ 215 3 433 26 0 164 993 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_031900473 chr12:55727082-55747326 Sample_02_0319 Neuroblastoma NB-EBc1 473 3 426 26 0 164 988 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_025300535 chr12:55727104-55747117 Sample_02_0253 Brain BE2C_DMSO 535 3 422 26 0 164 983 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_095600314 chr12:55727110-55757465 Sample_02_0956 Brain IDH1_2658 314 5 629 31 1 261 1806 GDF11,CD63,SARNP,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_118800447 chr12:55727130-55746142 Sample_02_1188 Brain GBM18 447 4 402 23 0 164 977 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_080200152 chr12:55727145-55746560 Sample_02_0802 Brain 3094 152 4 407 24 0 164 971 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_063300333 chr12:55727153-55746755 Sample_02_0633 Gastrointestinal Stromal GIST-48B_Imatinib 333 3 410 25 0 164 970 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_154400327 chr12:55727153-55760165 Sample_02_1544 Gastrointestinal Stromal GIST-882 327 8 693 34 1 262 1823 GDF11,CD63,SARNP,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_098200214 chr12:55727242-55746513 Sample_02_0982 Brain H3.3K27M-KO_BT245-C2P3 214 5 406 24 0 158 952 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_029900431 chr12:55727279-55746956 Sample_02_0299 Neuroblastoma CLB-MA 431 3 414 26 0 158 944 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_155900371 chr12:55727294-55760054 Sample_02_1559 Gastrointestinal Stromal GIST-8_PDGFRA e18 371 5 687 34 1 256 1797 GDF11,CD63,SARNP,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_096900197 chr12:55727350-55746731 Sample_02_0969 Brain H3.3K27M_PL637 197 3 406 25 0 156 931 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_022000229 chr12:55727359-55746824 Sample_02_0220 Brain BE2C_1 229 3 406 26 0 156 931 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_096000115 chr12:55727390-55746501 Sample_02_0960 Brain H3.3K27M_Tumor-derived cell-line_BT869p21-Rx_cells 115 4 401 24 0 156 918 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B
SE_01_002300353 chr12:55727437-55773637 Sample_01_0023 Embryo cardiac-muscle-cell 353 7 993 50 1 264 1803 GDF11,SARNP,CD63,METTL7B,RDH5,ITGA7,BLOC1S1,ORMDL2
SE_02_118900129 chr12:55727479-55746345 Sample_02_1189 Brain GBM22 129 4 395 24 0 156 899 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_027600243 chr12:55727498-55745644 Sample_02_0276 Retina FW15 243 3 388 23 0 134 898 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_031500402 chr12:55727521-55747058 Sample_02_0315 Neuroblastoma TR14 402 3 411 26 0 156 889 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_142000157 chr12:55727552-55746490 Sample_02_1420 Brain DIPG007 157 4 397 24 0 156 880 GDF11,CD63,BLOC1S1,RDH5,ITGA7,METTL7B
SE_02_004400111 chr12:55727712-55746747 Sample_02_0044 Embryo endodermal CyT49_ES_D5 111 4 392 23 0 155 854 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_004500203 chr12:55727769-55746848 Sample_02_0045 Embryo endodermal CyT49_ES_D7 203 4 393 24 0 155 844 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_01_005000309 chr12:55727855-55746901 Sample_01_0050 Embryo neural-cell 309 3 395 24 0 155 826 GDF11,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_00_001000420 chr12:55728457-55766757 Sample_00_0010 Embryo endodermal-cell 420 6 800 38 1 241 1549 GDF11,SARNP,CD63,METTL7B,RDH5,ITGA7,BLOC1S1
SE_02_074500566 chr12:55736806-55758246 Sample_02_0745 Embryo ES derived cardiac progenitor cells_day7 566 10 434 17 1 216 1108 GDF11,SARNP,CD63,BLOC1S1,ITGA7,RDH5
SE_02_004600420 chr12:55736838-55746748 Sample_02_0046 Embryo endodermal CyT49_ES_D10 420 3 195 9 0 117 255 GDF11,RDH5,ITGA7,BLOC1S1,CD63
SE_02_095500411 chr12:55737006-55746489 Sample_02_0955 Brain IDH1_2469 411 2 190 8 0 117 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5
SE_02_148501153 chr12:55737121-55747502 Sample_02_1485 Bone SK-ES-1 1153 3 212 10 0 116 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5
SE_02_004900301 chr12:55737285-55747429 Sample_02_0049 Embryo endodermal CyT49_GTtoH 301 2 206 9 0 113 255 GDF11,RDH5,ITGA7,BLOC1S1,CD63
SE_02_055600316 chr12:55737332-55746981 Sample_02_0556 iPSCs BOFS hiPSC cl1 316 2 191 9 0 113 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5
SE_02_148100918 chr12:55737344-55755398 Sample_02_1481 Bone MIC 918 5 370 14 1 204 1042 GDF11,SARNP,CD63,BLOC1S1,ITGA7,RDH5
SE_02_093400581 chr12:55737395-55746767 Sample_02_0934 Embryo H7-WT 581 2 179 8 0 113 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5
SE_02_055900678 chr12:55737415-55746613 Sample_02_0559 iPSCs FX52 iPSCs dC-T 678 2 178 7 0 113 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5
SE_00_004800062 chr12:55737487-55758248 Sample_00_0048 Embryo neuronal stem cell originated from H1 62 8 418 16 1 211 1108 GDF11,SARNP,CD63,BLOC1S1,ITGA7,RDH5
SE_02_049400506 chr12:55737535-55747199 Sample_02_0494 Islets differentiated hESCs Late pancreatic progenitor cells 506 2 190 9 0 113 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5
SE_02_147700850 chr12:55737567-55755945 Sample_02_1477 Bone EW-22 850 6 374 14 1 204 1042 GDF11,SARNP,CD63,BLOC1S1,ITGA7,RDH5
SE_02_068000371 chr12:55737618-55746758 Sample_02_0680 Embryo H1 hESC-derived neural progenitor cells_Smad_48hr 371 3 176 8 0 113 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5,MMP19,OR2AP1
SE_02_068100267 chr12:55737624-55746690 Sample_02_0681 Embryo H1 hESC-derived neural progenitor cells_Smad_72hr 267 4 174 7 0 113 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5,MMP19,OR2AP1
SE_02_067700445 chr12:55737833-55746790 Sample_02_0677 Embryo H1 hESC-derived neural progenitor cells_Smad_6hr 445 4 166 8 0 111 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5,MMP19,OR2AP1
SE_02_049500542 chr12:55737890-55746757 Sample_02_0495 Islets differentiated hESCs Early LSD1 inhibition PP2 542 3 165 8 0 111 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5
SE_02_049300494 chr12:55737897-55747958 Sample_02_0493 Islets differentiated hESCs Early pancreatic progenitor cells 494 3 196 9 0 111 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5
SE_02_056000746 chr12:55737962-55746573 Sample_02_0560 iPSCs FX52_Cas9-inactive Tet1_CGG sgRNA 746 2 161 7 0 111 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5
SE_02_086100668 chr12:55738079-55747807 Sample_02_0861 iPSCs SAH_WT 668 5 186 9 0 111 255 GDF11,CD63,BLOC1S1,ITGA7,RDH5
SE_02_003900422 chr12:55741726-55747744 Sample_02_0039 Embryo AFG 422 1 102 4 0 102 255 GDF11,RDH5,ITGA7,BLOC1S1,CD63
SE_02_003601315 chr12:55743149-55747854 Sample_02_0036 Embryo H7 1315 1 79 4 0 96 226 GDF11,RDH5,ITGA7,BLOC1S1,CD63
SE_02_004001344 chr12:55743160-55747755 Sample_02_0040 Embryo PFG 1344 1 77 4 0 96 221 GDF11,RDH5,ITGA7,BLOC1S1,CD63
SE_02_033000242 chr12:55743165-55747010 Sample_02_0330 Endoderm MHG 242 1 62 4 0 96 217 GDF11,RDH5,ITGA7,BLOC1S1,CD63
SE_02_004200362 chr12:55743215-55748107 Sample_02_0042 Embryo endodermal CyT49_ES_D0 362 1 83 4 0 90 192 GDF11,RDH5,ITGA7,BLOC1S1,CD63
SE_02_001900511 chr12:55743244-55746491 Sample_02_0019 Embryo Neural crest cells 511 1 48 2 0 88 179 GDF11,RDH5,ITGA7,BLOC1S1,CD63
SE_02_004800695 chr12:55743245-55746879 Sample_02_0048 Embryo endodermal CyT49_HE 695 1 54 4 0 88 179 GDF11,RDH5,ITGA7,BLOC1S1,CD63
SE_02_001800305 chr12:55743367-55748335 Sample_02_0018 Embryo NEC 305 1 85 4 0 77 130 GDF11,RDH5,ITGA7,BLOC1S1,CD63
Genomic distribution of SEs associated with GDF11
Genome Browser

The strength of the tissue affected by the gene

Expression of GDF11

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)