Gene Symbol

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Species : {{s}}

Tissue Type : {{s}}

SE-Gene Linking Strategies: Closest_Active Overlap Closest Proximal ALL

Fimo: 1.0E-12 1.0E-11 1.0E-10 1.0E-9 1.0E-8 1.0E-7 1.0E-6 none

Pathway Enriciment Threshold

FDR Adjust

Example Submit Reset

Function introduction  Guidance
Users can submit a gene list and select a tissue type to analyze genes^④ associated with upstream regulatory network, including associated SEs^③, TFs^② binding to these SEs and their upstream pathways^①.
1) Gene Symbol: Input a gene symbol set.
2) Tissue Type: Select one sample tissue type or all.
3) SE-Gene Linking Strategies: select different annotation strategies to link SEs with target genes.
4) Fimo: Set different statistical thresholds to control for false positivity.
5) Pathway Enriciment Threshold: Set a statistical significance threshold of pathway enrichment, which is calculated using hypergeometric test.