T(co)F Overview
T(co)F: Dnmt3b
Species: Mus musculus
Knock-Method: siRNA
T(co)F Class: Other C4 zinc finger-type factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: embryonic cardiomyocytes
Tissue Type: Heart
Biosample Type: Primary cell
# of Control: 3
# of Treat: 3
Data Source: GEO
Profile ID: GSE77514
Platform: GPL19057
Pubmed ID: 27306334

Dnmt3b- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Dnmt3b
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Dnmt3b
Upstream Pathway Annotation of Dnmt3b
T(co)F Pathway Name Source Gene Number
Dnmt3b EPIGENETIC_REGULATION_OF_GENE_EXPRESSION REACTOME 112
Dnmt3b PRC2_METHYLATES_HISTONES_AND_DNA REACTOME 81
Dnmt3b SUMOYLATION REACTOME 165
Dnmt3b METABOLISM_OF_PROTEINS REACTOME 1657
Dnmt3b POST_TRANSLATIONAL_PROTEIN_MODIFICATION REACTOME 1310
Dnmt3b GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Dnmt3b GLUTATHIONE_AND_ONECARBON_METABOLISM WP 31
Dnmt3b ONECARBON_METABOLISM WP 29
Dnmt3b MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY WP 290
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Dnmt3b
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)