T(co)F Overview
T(co)F: Dnmt3a
Species: Mus musculus
Knock-Method: knockout
T(co)F Class: Other C4 zinc finger-type factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: Hematopoietic stem cell (HSC)
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Stem cell
# of Control: 3
# of Treat: 3
Data Source: GEO
Profile ID: GSE27322
Platform: GPL1261
Pubmed ID: 22138693

Dnmt3a- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of Dnmt3a
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of Dnmt3a
Upstream Pathway Annotation of Dnmt3a
T(co)F Pathway Name Source Gene Number
Dnmt3a EPIGENETIC_REGULATION_OF_GENE_EXPRESSION REACTOME 112
Dnmt3a PRC2_METHYLATES_HISTONES_AND_DNA REACTOME 81
Dnmt3a RMTS_METHYLATE_HISTONE_ARGININES REACTOME 71
Dnmt3a CHROMATIN_MODIFYING_ENZYMES REACTOME 205
Dnmt3a GENE_EXPRESSION_TRANSCRIPTION REACTOME 1061
Dnmt3a GLUTATHIONE_AND_ONECARBON_METABOLISM WP 31
Dnmt3a ONECARBON_METABOLISM_AND_RELATED_PATHWAYS WP 52
Dnmt3a ONECARBON_METABOLISM WP 29
Dnmt3a MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY WP 290
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of Dnmt3a
T(co)F Expression in Mouse Cell (Fantom5) T(co)F Expression in Mouse Tissue (Fantom5)