T(co)F Overview
T(co)F: YY1
Species: Homo sapiens
Knock-Method: knockdown
T(co)F Class: C2H2 zinc finger factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: HepG2
Tissue Type: Liver
Biosample Type: Cell line
# of Control: 14
# of Treat: 8
Data Source: GEO
Profile ID: GSE158884
Platform: GPL16791
Pubmed ID: 34099540

YY1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of YY1
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of YY1
Upstream Pathway Annotation of YY1
T(co)F Pathway Name Source Gene Number
YY1 DNA Damage Recognition in GG-NER Reactome 38
YY1 Notch-mediated HES/HEY network PID 48
YY1 Notch signaling pathway PID 58
YY1 p53 pathway PID 59
YY1 mTOR signaling pathway PID 66
YY1 Notch NetPath 76
YY1 E2F transcription factor network PID 77
YY1 Signaling events mediated by HDAC Class I PID 89
YY1 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome 120
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of YY1
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines