T(co)F Overview
T(co)F: WT1
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: C2H2 zinc finger factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: MCF7
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 3
# of Treat: 1
Data Source: GEO
Profile ID: GSE31912
Platform: GPL570
Pubmed ID: 22536322

WT1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of WT1
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of WT1
Upstream Pathway Annotation of WT1
T(co)F Pathway Name Source Gene Number
WT1 BMP signaling in Drosophila ( BMP signaling in Drosophila ) INOH 7
WT1 BMP signaling in Drosophila (dorsal midline) ( BMP signaling in Drosophila ) INOH 7
WT1 BMP signaling in Drosophila (dorsolateral) ( BMP signaling in Drosophila ) INOH 7
WT1 BMP signaling pathway ( TGF-beta_BMP Diagram(MolecularVariation) ) INOH 34
WT1 TGF-beta_super_family_signaling_pathway(canonical) ( TGF-beta_BMP Diagram(MolecularVariation) ) INOH 51
WT1 Regulation of Telomerase PID 70
WT1 p73 transcription factor network PID 80
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of WT1
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines