T(co)F Overview
T(co)F: PAX3
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Paired box factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: MCF7
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 3
# of Treat: 2
Data Source: GEO
Profile ID: GSE31912
Platform: GPL570
Pubmed ID: 22536322

PAX3- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of PAX3
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of PAX3
Upstream Pathway Annotation of PAX3
T(co)F Pathway Name Source Gene Number
PAX3 Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways 40
PAX3 Hs_Ectoderm_Differentiation_WP2858_89329 WikiPathways 56
PAX3 Regulation of retinoblastoma protein PID 67
PAX3 HATs acetylate histones Reactome 142
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of PAX3
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines