T(co)F Overview
T(co)F: MYB
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Tryptophan cluster factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: PC-3M
Tissue Type: Prostate
Biosample Type: Cell line
# of Control: 3
# of Treat: 3
Data Source: GEO
Profile ID: GSE49286
Platform: GPL10558
Pubmed ID: 24847116

MYB- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of MYB
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of MYB
Upstream Pathway Annotation of MYB
T(co)F Pathway Name Source Gene Number
MYB IL2 signaling events mediated by PI3K PID 38
MYB Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways 40
MYB Notch-mediated HES/HEY network PID 48
MYB IL4-mediated signaling events PID 66
MYB AP-1 transcription factor network PID 71
MYB C-MYB transcription factor network PID 87
MYB Prolactin NetPath 105
MYB Factors involved in megakaryocyte development and platelet production Reactome 111
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of MYB
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines