T(co)F Overview
T(co)F: IRF4
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Tryptophan cluster factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: Cutaneous T cell lymphoma HuT-102 cells
Tissue Type: Skin
Biosample Type: Primary cell
# of Control: 2
# of Treat: 2
Data Source: GEO
Profile ID: GSE22036
Platform: GPL570
Pubmed ID: 21498517

IRF4- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of IRF4
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of IRF4
Upstream Pathway Annotation of IRF4
T(co)F Pathway Name Source Gene Number
IRF4 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID 50
IRF4 IL4-mediated signaling events PID 66
IRF4 Interferon alpha/beta signaling Reactome 67
IRF4 Hs_B_Cell_Receptor_Signaling_Pathway_WP23_89900 WikiPathways 71
IRF4 Interferon gamma signaling Reactome 88
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of IRF4
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines