T(co)F Overview
T(co)F: FOXA1
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Fork head / winged helix factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: MCF7
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 6
# of Treat: 6
Data Source: GEO
Profile ID: GSE25316
Platform: GPL10558
Pubmed ID: 21151129

FOXA1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of FOXA1
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of FOXA1
Upstream Pathway Annotation of FOXA1
T(co)F Pathway Name Source Gene Number
FOXA1 FOXA1 transcription factor network PID 45
FOXA1 FOXA2 and FOXA3 transcription factor networks PID 45
FOXA1 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways 62
FOXA1 Direct p53 effectors PID 141
FOXA1 AndrogenReceptor NetPath 167
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of FOXA1
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines