T(co)F Overview
T(co)F: LMNA
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Others
T(co)F Superclass: TcoF-DB_TcoF
Biosample Name: K562
Tissue Type: Haematopoietic_and_lymphoid_tissue
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: ENCODE
Profile ID: ENCSR071JWS
Platform: -
Pubmed ID: 22955616

LMNA- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of LMNA
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of LMNA
Upstream Pathway Annotation of LMNA
T(co)F Pathway Name Source Gene Number
LMNA Initiation of Nuclear Envelope Reformation Reactome 13
LMNA Depolymerisation of the Nuclear Lamina Reactome 15
LMNA Hs_G13_Signaling_Pathway_WP524_72112 WikiPathways 18
LMNA FAS signaling pathway PANTHER 37
LMNA XBP1(S) activates chaperone genes Reactome 53
LMNA Caspase Cascade in Apoptosis PID 57
LMNA Arrhythmogenic right ventricular cardiomyopathy (ARVC) KEGG 71
LMNA Meiotic synapsis Reactome 76
LMNA Hypertrophic cardiomyopathy (HCM) KEGG 78
LMNA Dilated cardiomyopathy KEGG 85
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of LMNA
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines