T(co)F Overview
T(co)F: CDX2
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Homeo domain factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: COLO320
Tissue Type: Colon
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: GEO
Profile ID: GSE30181
Platform: GPL4133
Pubmed ID: 23112155

CDX2- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of CDX2
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of CDX2
Upstream Pathway Annotation of CDX2
T(co)F Pathway Name Source Gene Number
CDX2 POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation Reactome 10
CDX2 Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Reactome 20
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of CDX2
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines