T(co)F Overview
T(co)F: SALL4
Species: Homo sapiens
Knock-Method: shRNA
T(co)F Class: C2H2 zinc finger factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: H661
Tissue Type: Lung
Biosample Type: Cell line
# of Control: 3
# of Treat: 3
Data Source: GEO
Profile ID: GSE68959
Platform: GPL6244
Pubmed ID: 27705911

SALL4- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of SALL4
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of SALL4
Upstream Pathway Annotation of SALL4
T(co)F Pathway Name Source Gene Number
SALL4 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Reactome 13
SALL4 Transcriptional regulation of pluripotent stem cells Reactome 28
SALL4 Regulation of nuclear beta catenin signaling and target gene transcription PID 80
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of SALL4
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines