T(co)F Overview
T(co)F: TCF4
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Basic helix-loop-helix factors (bHLH)
T(co)F Superclass: Basic domains
Biosample Name: CTXOE03
Tissue Type: Brain
Biosample Type: Cell line
# of Control: 4
# of Treat: 8
Data Source: GEO
Profile ID: GSE62085
Platform: GPL10558
Pubmed ID: 27689884

TCF4- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of TCF4
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of TCF4
Upstream Pathway Annotation of TCF4
T(co)F Pathway Name Source Gene Number
TCF4 CDO in myogenesis Reactome 29
TCF4 ID NetPath 38
TCF4 Hs_Corticotropin-releasing_hormone_signaling_pathway_WP2355_90017 WikiPathways 41
TCF4 Coregulation of Androgen receptor activity PID 61
TCF4 Regulation of nuclear beta catenin signaling and target gene transcription PID 80
TCF4 Formation of the beta-catenin:TCF transactivating complex Reactome 88
TCF4 Wnt NetPath 118
TCF4 AndrogenReceptor NetPath 167
TCF4 TGF_beta_Receptor NetPath 220
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of TCF4
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines