T(co)F Overview
T(co)F: NFATC3
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Others
T(co)F Superclass: beta-Scaffold Factors
Biosample Name: CD4+ T cells
Tissue Type: Peripheral_blood
Biosample Type: Primary cell
# of Control: 8
# of Treat: 4
Data Source: GEO
Profile ID: GSE46333
Platform: GPL14550
Pubmed ID: 24401939

NFATC3- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of NFATC3
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of NFATC3
Upstream Pathway Annotation of NFATC3
T(co)F Pathway Name Source Gene Number
NFATC3 Signaling by Wnt Reactome 10
NFATC3 CLEC7A (Dectin-1) induces NFAT activation Reactome 13
NFATC3 Calcium signaling in the CD4+ TCR pathway PID 29
NFATC3 Axon guidance mediated by netrin PANTHER 30
NFATC3 Validated transcriptional targets of AP1 family members Fra1 and Fra2 PID 37
NFATC3 FCERI mediated Ca+2 mobilization Reactome 41
NFATC3 FOXM1 transcription factor network PID 43
NFATC3 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID 50
NFATC3 Role of Calcineurin-dependent NFAT signaling in lymphocytes PID 54
NFATC3 Downstream signaling in nave CD8+ T cells PID 69
NFATC3 VEGF signaling pathway KEGG 70
NFATC3 B cell receptor signaling pathway KEGG 70
NFATC3 Hs_B_Cell_Receptor_Signaling_Pathway_WP23_89900 WikiPathways 71
NFATC3 AP-1 transcription factor network PID 71
NFATC3 T cell receptor signaling pathway KEGG 105
NFATC3 Natural killer cell mediated cytotoxicity KEGG 125
NFATC3 Axon guidance KEGG 126
NFATC3 Wnt signaling pathway KEGG 135
NFATC3 BCR NetPath 161
NFATC3 Inflammation mediated by chemokine and cytokine signaling pathway PANTHER 189
NFATC3 Wnt signaling pathway PANTHER 250
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of NFATC3
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines