T(co)F Overview
T(co)F: POLR3A
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Others
T(co)F Superclass: ENCODE_TF
Biosample Name: MCF7
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 1
# of Treat: 1
Data Source: GEO
Profile ID: GSE42239
Platform: GPL570
Pubmed ID: 26067234

POLR3A- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of POLR3A
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of POLR3A
Upstream Pathway Annotation of POLR3A
T(co)F Pathway Name Source Gene Number
POLR3A RNA Polymerase III Chain Elongation Reactome 18
POLR3A Cytosolic sensors of pathogen-associated DNA Reactome 22
POLR3A RNA Polymerase III Transcription Termination Reactome 23
POLR3A RNA Polymerase III Transcription Initiation From Type 2 Promoter Reactome 27
POLR3A RNA Polymerase III Transcription Initiation From Type 1 Promoter Reactome 28
POLR3A RNA Polymerase III Transcription Initiation From Type 3 Promoter Reactome 28
POLR3A RNA Polymerase III Abortive And Retractive Initiation Reactome 41
POLR3A Cytosolic DNA-sensing pathway KEGG 56
POLR3A Pyrimidine metabolism KEGG 99
POLR3A Purine metabolism KEGG 159
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of POLR3A
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines