T(co)F Overview
T(co)F: GATA3
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Other C4 zinc finger-type factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: MCF7
Tissue Type: Mammary_gland
Biosample Type: Cell line
# of Control: 10
# of Treat: 12
Data Source: GEO
Profile ID: GSE39623
Platform: GPL6947
Pubmed ID: 23172872

GATA3- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of GATA3
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of GATA3
Upstream Pathway Annotation of GATA3
T(co)F Pathway Name Source Gene Number
GATA3 IL27-mediated signaling events PID 26
GATA3 Hs_White_fat_cell_differentiation_WP3946_90940 WikiPathways 30
GATA3 Hs_Endochondral_Ossification_WP474_87977 WikiPathways 43
GATA3 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID 50
GATA3 Notch signaling pathway PID 58
GATA3 Regulation of nuclear SMAD2/3 signaling PID 82
GATA3 Glucocorticoid receptor regulatory network PID 85
GATA3 C-MYB transcription factor network PID 87
GATA3 Factors involved in megakaryocyte development and platelet production Reactome 111
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of GATA3
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines