T(co)F Overview
T(co)F: NKX2-1
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: Homeo domain factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: HCC4019
Tissue Type: Lung
Biosample Type: Cell line
# of Control: 2
# of Treat: 2
Data Source: GEO
Profile ID: GSE28480
Platform: GPL6947
Pubmed ID: 21907921

NKX2-1- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of NKX2-1
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of NKX2-1
Upstream Pathway Annotation of NKX2-1
T(co)F Pathway Name Source Gene Number
NKX2-1 FOXA2 and FOXA3 transcription factor networks PID 45
NKX2-1 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways 62
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of NKX2-1
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines