T(co)F Overview
T(co)F: EGR3
Species: Homo sapiens
Knock-Method: siRNA
T(co)F Class: C2H2 zinc finger factors
T(co)F Superclass: Zinc-coordinating DNA-binding domains
Biosample Name: HUVEC
Tissue Type: Umbilical_vein
Biosample Type: Cell line
# of Control: 9
# of Treat: 12
Data Source: GEO
Profile ID: GSE18913
Platform: GPL570
Pubmed ID: 19965691

EGR3- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of EGR3
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of EGR3
Upstream Pathway Annotation of EGR3
T(co)F Pathway Name Source Gene Number
EGR3 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID 50
EGR3 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways 153
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of EGR3
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines