T(co)F Overview
T(co)F: HNF1A
Species: Homo sapiens
Knock-Method: shRNA
T(co)F Class: Homeo domain factors
T(co)F Superclass: Helix-turn-helix domains
Biosample Name: HuH7
Tissue Type: Liver
Biosample Type: Cell line
# of Control: 1
# of Treat: 1
Data Source: GEO
Profile ID: GSE103128
Platform: GPL18180
Pubmed ID: 29466992

HNF1A- Target Gene Network

T(co)F   
up-regulated gene   
down-regulated gene   

#T(co)F-target relationships supported by the ChIP-seq data are represented by the thick lines

Gene Type: # of Top Genes:
Target Gene Information of HNF1A
Target Gene T(co)F Mean
Expr. of
Control 		Mean
Expr. of
Treat
Fold Change Log2FC Rank P-value Corrected
_P 		Promoter
_T(co)F 		SE_T(co)F TE_T(co)F
#When clicking the '' button in the last three column of the table, the users can view T(co)Fs supported by the ChIP-seq/motif data in red.
Function Analysis of Downstream Target Genes of HNF1A
Upstream Pathway Annotation of HNF1A
T(co)F Pathway Name Source Gene Number
HNF1A Regulation of gene expression in beta cells Reactome 17
HNF1A Maturity onset diabetes of the young KEGG 25
HNF1A FOXA2 and FOXA3 transcription factor networks PID 45
HNF1A Presenilin action in Notch and Wnt signaling PID 46
HNF1A IL6 NetPath 85
Target Gene Expression Analysis
Heatmap of Unsupervised Hierarchical Clustering Scatter Diagram of Differential Expression
Expression Atlas of HNF1A
T(co)F Expression in Human Normal Tissues (GTEx) T(co)F Expression in Cancer Cell Lines (CCLE)
T(co)F Expression in Human Cancers (TCGA) T(co)F Expression in Encode Cell Lines