SEdb 2.0
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Gene overview

Strategies/Algorithm: overlap Ensembl ID: ENSG00000243709
Gene: LEFTY1 Gene type: protein_coding
Strand: - External links:
Genomic region: chr1:225886282-225911382 Genome Browser:

Super-enhancer search result of gene-based

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SE ID SE Region Sample ID Tissue type Biosample name SE rank Element Common SNP eQTL Risk SNP TFBS CRISPR Cas9 Gene
SE_02_155300487 chr1:225833916-225896392 Sample_02_1553 Gastrointestinal Stromal GIST-2_KIT e11 487 18 1856 249 9 232 3704 EPHX1,LEFTY1,TMEM63A,LEFTY2,PYCR2,MIR6741
SE_02_098901101 chr1:225834150-225897305 Sample_02_0989 Kidney kidney cortex_WT 1101 17 1869 250 9 234 3704 EPHX1,LEFTY1,TMEM63A,LEFTY2,PYCR2,MIR6741
SE_00_005600259 chr1:225834745-225899005 Sample_00_0056 Sigmoid colon sigmoid colon 3y 259 20 1891 256 9 236 3704 EPHX1,LEFTY1,TMEM63A,LEFTY2,PYCR2,MIR6741
SE_02_067200187 chr1:225843801-225920690 Sample_02_0672 Endometrium endometrium cancer_DSG 187 18 2219 277 10 222 3408 LEFTY1,EPHX1,PYCR2,TMEM63A,LEFTY2,MIR6741
SE_01_008401279 chr1:225845318-225898898 Sample_01_0084 Spleen spleen 1279 8 1540 222 5 208 3058 LEFTY1,EPHX1,TMEM63A,LEFTY2,PYCR2
SE_02_016500554 chr1:225850654-225899295 Sample_02_0165 Lung H2087_LCC2 554 8 1396 207 4 191 2312 LEFTY1,TMEM63A,EPHX1,LEFTY2,PYCR2
SE_02_045400874 chr1:225854174-225899854 Sample_02_0454 Th17 lymphocytes Th17-IL-10+ Day 0 874 11 1288 193 4 180 2116 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_105100045 chr1:225861325-225910884 Sample_02_1051 Esophagus Eso26 45 9 1420 190 6 161 1740 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_067400188 chr1:225863476-225919990 Sample_02_0674 Endometrium E1_FA 188 15 1596 193 5 139 1559 PYCR2,TMEM63A,LEFTY1,EPHX1,LEFTY2,MIR6741
SE_01_010900412 chr1:225863519-225897961 Sample_01_0109 Colon transverse colon_54y 412 8 979 142 3 132 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_01_005800305 chr1:225863721-225899370 Sample_01_0058 Prostate PC-3 305 7 1017 151 3 133 1526 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_018000726 chr1:225863925-225897766 Sample_02_0180 melanoma CJM 726 5 965 140 3 132 1526 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_035400309 chr1:225863928-225909078 Sample_02_0354 Colon Colo205 309 6 1296 174 5 138 1526 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_035300122 chr1:225863945-225908964 Sample_02_0353 Colon HT29 122 7 1292 174 5 138 1526 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_081900150 chr1:225863993-225911427 Sample_02_0819 Ovary Mucinous ovarian cancer 150 11 1350 174 5 138 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_044800944 chr1:225864001-225897821 Sample_02_0448 Bone MNNG 944 14 968 140 3 132 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_008600533 chr1:225864030-225899706 Sample_02_0086 Pancreas CAPAN1 533 4 1016 150 3 135 1526 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_024000663 chr1:225864030-225911562 Sample_02_0240 Colon V429_2 663 11 1357 174 5 138 1526 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_137100176 chr1:225864088-225898269 Sample_02_1371 Pancreas Patu899S-untreated 176 10 976 142 3 132 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_071100220 chr1:225864144-225897937 Sample_02_0711 Pancreas hN35_organoid 220 12 968 141 3 132 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_042300383 chr1:225864539-225899293 Sample_02_0423 Skin A375 383 6 999 148 3 133 1526 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_070300431 chr1:225864549-225908783 Sample_02_0703 Pancreas PATU8988S WT 431 8 1279 173 5 138 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_024100032 chr1:225864664-225911589 Sample_02_0241 Colon V456 32 10 1346 173 5 137 1526 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_070900173 chr1:225864669-225911337 Sample_02_0709 Pancreas hT85_organoid 173 9 1339 173 5 137 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_047700084 chr1:225864671-225911610 Sample_02_0477 Colon intestinal epithelial organoids_139a 84 18 1347 174 5 137 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_025700034 chr1:225864673-225921614 Sample_02_0257 Endometrioid endometrioid_adenocarcinoma_TumorA 34 6 1618 195 6 151 1816 PYCR2,LEFTY1,TMEM63A,EPHX1,LEFTY2
SE_02_047800103 chr1:225864685-225910878 Sample_02_0478 Colon normal colon mucosa 103 17 1325 173 5 137 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_088400654 chr1:225864686-225898384 Sample_02_0884 Colon LoVo 654 7 968 142 3 131 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_023600296 chr1:225864688-225908893 Sample_02_0236 Colon V206 296 10 1278 173 5 137 1526 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_125800579 chr1:225864700-225898768 Sample_02_1258 Liver Pancreatic cancer cells derived from liver metastasis 579 6 983 145 3 131 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_136700471 chr1:225864719-225898851 Sample_02_1367 Pancreas Capan1-untreated 471 14 984 145 3 131 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_125500115 chr1:225864797-225898927 Sample_02_1255 Bladder Bladder tumor Luminal2 115 9 981 145 3 131 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_006800264 chr1:225864984-225899564 Sample_02_0068 Skin A375_DMSO 264 6 993 148 3 131 1526 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_149000094 chr1:225865012-225887195 Sample_02_1490 Lung H2087 94 4 632 89 2 92 1107 TMEM63A,LEFTY1,EPHX1,PYCR2,MIR6741
SE_02_085300358 chr1:225865508-225900126 Sample_02_0853 Mammary gland MCF7L-TamR 358 9 990 148 3 133 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_127500708 chr1:225865555-225897623 Sample_02_1275 Prostate PC3_Vorinostat 708 14 926 137 3 130 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_075000903 chr1:225865690-225909848 Sample_02_0750 Lymphoma Rec-1_GSI 903 6 1277 171 5 136 1526 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_101600190 chr1:225865767-225919111 Sample_02_1016 Embryo H9_Mesendoderm_24h 190 7 1521 188 5 137 1512 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_074200099 chr1:225868725-225900667 Sample_02_0742 Embryo ESCs_day0 99 7 922 142 3 109 1185 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_01_008501043 chr1:225870671-225920544 Sample_01_0085 Stomach stomach 1043 6 1437 167 6 113 1329 PYCR2,LEFTY1,TMEM63A,EPHX1,LEFTY2
SE_02_047500866 chr1:225870886-225898226 Sample_02_0475 Induced hepatocyte-like cells hepatocyte-like cells 866 8 806 115 3 105 1180 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_071000424 chr1:225871132-225891249 Sample_02_0710 Pancreas hN34_organoid 424 9 613 83 2 99 1135 TMEM63A,LEFTY1,EPHX1,PYCR2,MIR6741
SE_00_005800370 chr1:225871840-225897262 Sample_00_0058 Stomach stomach 34y 370 7 759 109 3 97 1110 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_074800034 chr1:225872759-225919951 Sample_02_0748 Mammary gland HCC1599_WO 34 8 1363 162 5 105 1094 PYCR2,TMEM63A,LEFTY1,EPHX1,LEFTY2,MIR6741
SE_02_074900056 chr1:225872886-225919936 Sample_02_0749 Mammary gland HCC1599_GSI 56 6 1359 162 5 105 1093 PYCR2,TMEM63A,LEFTY1,EPHX1,LEFTY2,MIR6741
SE_02_035800328 chr1:225872971-225891468 Sample_02_0358 Colon LS180 328 2 570 80 2 95 1062 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_146500381 chr1:225873429-225897687 Sample_02_1465 Ovary CAOV4cis 381 6 724 108 3 98 1062 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_020500236 chr1:225873658-225898239 Sample_02_0205 Stomach Gastric_Primary_Sample_T 236 6 731 110 3 98 1062 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_129900652 chr1:225873991-225897864 Sample_02_1299 Liver liver 652 10 717 106 3 94 1062 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_129600525 chr1:225874105-225898460 Sample_02_1296 Perigastric lymph node Perigastric lymph node 525 7 730 111 3 94 1060 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_032800013 chr1:225874163-225901877 Sample_02_0328 Embryo H9_naive 13 3 822 121 3 97 1046 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_129700579 chr1:225874273-225897276 Sample_02_1297 Lung lung 579 7 694 104 3 93 1044 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_01_007100194 chr1:225874372-225897939 Sample_01_0071 Pancreas body-of-pancreas 194 5 709 106 3 92 1035 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_066000552 chr1:225874554-225897690 Sample_02_0660 Mammary gland MCF10DCIS 552 6 694 105 3 92 1005 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_069800231 chr1:225874600-225898364 Sample_02_0698 Lung NCI-H1048-cas9_sgPOU2F3 231 6 708 108 3 89 1005 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_01_009900251 chr1:225874653-225897888 Sample_01_0099 Colon transverse colon 251 10 696 106 3 89 1005 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_01_008000391 chr1:225874681-225898062 Sample_01_0080 Prostate prostate 391 4 696 106 3 89 1005 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_00_004100945 chr1:225874683-225897726 Sample_00_0041 Stomach stomach_3y 945 4 686 105 3 89 1005 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_019600082 chr1:225874839-225891892 Sample_02_0196 Stomach NCC59 82 3 527 75 2 86 1005 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_00_004200479 chr1:225874923-225897966 Sample_00_0042 Stomach stomach_30y 479 3 687 106 3 89 1005 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_00_003500218 chr1:225874938-225899440 Sample_00_0035 Sigmoid colon sigmoid-colon 218 8 729 115 3 90 1005 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_00_003000072 chr1:225874991-225898960 Sample_00_0030 Pancreas pancreas 72 7 713 111 3 90 1005 LEFTY1,TMEM63A,EPHX1,PYCR2,LEFTY2
SE_02_066100765 chr1:225875001-225897277 Sample_02_0661 Mammary gland MCF10DCIS-TetTCF7 765 8 670 103 3 88 1005 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_049400367 chr1:225875051-225916176 Sample_02_0494 Islets differentiated hESCs Late pancreatic progenitor cells 367 11 1179 144 5 96 1005 TMEM63A,LEFTY1,EPHX1,LEFTY2,PYCR2,MIR6741
SE_02_006500161 chr1:225875411-225916398 Sample_02_0065 Embryo KO2-Late_G1 161 7 1176 145 5 94 1005 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_00_001400582 chr1:225877101-225897932 Sample_00_0014 Heart left ventricle heart-left-ventricle 582 3 626 98 3 86 1005 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_032601263 chr1:225877512-225898280 Sample_02_0326 Liver hepatocytes_d3 1263 4 619 97 2 75 954 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_032501094 chr1:225877669-225898188 Sample_02_0325 Liver hepatocytes_d1 1094 5 605 97 2 75 925 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_075200038 chr1:225877689-225912398 Sample_02_0752 Embryo ES-derived progenitors_DE_wild type 38 6 1005 131 4 81 918 TMEM63A,LEFTY1,MIR6741,PYCR2,LEFTY2
SE_02_057900534 chr1:225877977-225911070 Sample_02_0579 Blood HEL_sgNeg2 534 18 966 126 4 81 904 TMEM63A,LEFTY1,MIR6741,PYCR2,LEFTY2
SE_02_075500081 chr1:225877996-225912917 Sample_02_0755 Embryo ES-derived progenitors_DE FOXA2 -/- 81 9 1004 128 4 81 904 TMEM63A,LEFTY1,MIR6741,PYCR2,LEFTY2
SE_02_032701090 chr1:225878068-225898333 Sample_02_0327 Liver hepatocytes_d6 1090 4 596 94 2 75 904 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_020400249 chr1:225878488-225892640 Sample_02_0204 Stomach IM95 249 2 434 67 1 71 904 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_004200020 chr1:225878985-225901043 Sample_02_0042 Embryo endodermal CyT49_ES_D0 20 3 637 103 2 77 904 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_122600181 chr1:225879011-225906028 Sample_02_1226 Bone marrow RPMI-8226 181 3 795 114 2 77 904 TMEM63A,LEFTY1,MIR6741,PYCR2,LEFTY2
SE_00_002400137 chr1:225879984-225911761 Sample_00_0024 Embryo mesendoderm 137 7 917 121 3 80 790 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_004600154 chr1:225880153-225916923 Sample_02_0046 Embryo endodermal CyT49_ES_D10 154 9 1048 128 3 81 790 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_157000981 chr1:225880192-225918467 Sample_02_1570 iPSCs EiPSC 981 13 1085 130 3 81 790 TMEM63A,LEFTY1,MIR6741,PYCR2,LEFTY2
SE_02_107400318 chr1:225880570-225899211 Sample_02_1074 Lymphoma BC-1 318 3 545 90 1 75 790 TMEM63A,LEFTY1,MIR6741,PYCR2,LEFTY2
SE_02_003600929 chr1:225880948-225900400 Sample_02_0036 Embryo H7 929 4 563 93 1 77 790 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_006400161 chr1:225881040-225908937 Sample_02_0064 Embryo DN-Early_G1 161 5 820 115 3 80 790 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_011400524 chr1:225881041-225917721 Sample_02_0114 Mammary gland CAL51 524 9 1047 128 3 81 790 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_004300001 chr1:225881062-225916991 Sample_02_0043 Embryo endodermal CyT49_ES_D2 1 8 1025 127 3 81 790 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_006700237 chr1:225881069-225901844 Sample_02_0067 Embryo AzH-G2/M 237 3 600 96 1 77 790 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_003800099 chr1:225886037-225892122 Sample_02_0038 Embryo DE 99 1 201 28 0 55 583 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_024200583 chr1:225886282-225895092 Sample_02_0242 Colon V481 583 1 275 41 1 55 565 LEFTY1,TMEM63A,PYCR2,LEFTY2
SE_02_041800086 chr1:225887965-225900526 Sample_02_0418 Embryo H9_Null+EZH2 86 3 352 57 1 19 247 LEFTY1,TMEM63A,PYCR2,LEFTY2
Genomic distribution of SEs associated with LEFTY1
Genome Browser

The strength of the tissue affected by the gene

Expression of LEFTY1

Cell line (ENCODE) Primary cell (ENCODE)Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)