General Details

Super-enhancer:SE_02_33600758
Genomic Locus: chr12: 28385792-28399797
Size/Length:14005bp
Conservation:0.0483398
BioSample Type:Cell line
Tissue Type:Haematopoietic and lymphoid tissue
Sample Name:SET2
Source:NCBI GEO/SRA
Element:1
Rank:758
ChIP Density(Case):14010.602
ChIP Density(Input):2932.647

Super-enhancer Associated Network


* The complex regulatory networks formed by this SE , SE associated genes , TFs binding to the SE and their upstream pathways can be interactively visualized.


Fimo:
SE-Gene Linking Strategies:
Pathway Enriciment Threshold:
Top Pathway:
 



Super-enhancer Associated Statistics

Associated Gene Details

ROSE Overlap:.
ROSE Proximal:CCDC91
ROSE Closest:CCDC91
The Closest Active:CCDC91

Factors Binding to Super-enhancer




Using these SE element regions to analyze by online tools GREAT *The TFs binding to this SE identified by ChIP-seq.

Chrome Element_Start Element_End TF TF Source TF_Start TF_End TF Class Master TF
chr12 28385792 28399797 CDK8 Remap_0281 28388012 28388192 TcoF-DB_TcoF N
chr12 28385792 28399797 CDK8 Remap_0281 28395415 28395615 TcoF-DB_TcoF N
chr12 28385792 28399797 CDK8 Remap_0281 28395761 28396517 TcoF-DB_TcoF N
chr12 28385792 28399797 STAT1 ChIP-Atlas_1205 28395519 28396373 Immunoglobulin fold N
chr12 28385792 28399797 STAT1 ChIP-Atlas_1206 28395991 28396254 Immunoglobulin fold N

Using these SE element regions to analyze by online tools GREAT * The TFs binding to this SE predicted by Motif.

Chrome Element_Start Element_End TF Database TF_Start TF_End Score P_Value TF Class Master TF
chr12 28385792 28399797 CTCF Transfac.V$CTCF_01 28390556 28390575 19.31650 1.65e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 CTCF Transfac.V$CTCF_02 28390554 28390573 17.49230 6.42e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 CTCF JASPAR2014.MA0139.1 28390557 28390575 17.16390 7.8e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 ELSPBP1 Transfac.V$E12_Q6 28395239 28395249 16.93520 2.18e-07 UNKNOW N
chr12 28385792 28399797 ERG JASPAR2014.MA0474.1 28388072 28388082 17.53060 1.81e-07 Helix-turn-helix domains N
chr12 28385792 28399797 ETS1 JASPAR2014.MA0098.2 28388069 28388083 18.82760 7.57e-08 Helix-turn-helix domains Y
chr12 28385792 28399797 FLI1 JASPAR2014.MA0475.1 28388072 28388082 17.81480 3.14e-07 Helix-turn-helix domains Y
chr12 28385792 28399797 FOXJ3 Transfac.V$FOXJ3_06 28396889 28396905 14.50700 9.22e-07 Helix-turn-helix domains N
chr12 28385792 28399797 FOXJ3 Uniprobe.UP00039_2 28396889 28396905 14.42960 9.58e-07 Helix-turn-helix domains N
chr12 28385792 28399797 HOXD8 Transfac.V$HOXD8_01 28388262 28388278 16.09800 7.4e-07 Helix-turn-helix domains N
chr12 28385792 28399797 HOXD8 Homeodomain.UP00168_1 28388262 28388278 16.09300 7.23e-07 Helix-turn-helix domains N
chr12 28385792 28399797 HOXD8 Uniprobe.UP00168_1 28388262 28388278 16.09300 7.23e-07 Helix-turn-helix domains N
chr12 28385792 28399797 ID4 Transfac.V$ID4_01 28395239 28395248 14.96720 8.07e-07 Basic domains N
chr12 28385792 28399797 IRF1 JASPAR2014.MA0050.2 28391312 28391332 18.82260 2.76e-07 Helix-turn-helix domains N
chr12 28385792 28399797 KLF11 Transfac.V$FKLF_Q5 28391953 28391962 15.52780 7.83e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 MAFB Transfac.V$MAFB_03 28387269 28387283 14.76050 2.04e-07 Basic domains N
chr12 28385792 28399797 MAFB Uniprobe.UP00045_2 28387269 28387283 14.74850 1.95e-07 Basic domains N
chr12 28385792 28399797 MECOM JASPAR2014.MA0029.1 28392775 28392788 19.35960 1.74e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 MYEF2 Transfac.V$HMEF2_Q6 28397997 28398012 17.59260 5.41e-07 alpha-Helices exposed by beta-structures N
chr12 28385792 28399797 NKX6-1 Transfac.V$NKX61_01 28398558 28398570 18.32000 2.25e-07 Helix-turn-helix domains N
chr12 28385792 28399797 NR2F1 Transfac.V$NR2F1_03 28394712 28394727 16.49480 9.07e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 NR2F1 Jolma2013.NR2F1_DBD_2 28394712 28394727 16.51850 9.26e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 NR2F6 Jolma2013.Nr2f6_DBD 28394712 28394726 16.57730 3e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 PAX5 JASPAR2014.MA0014.2 28385878 28385896 17.85480 3.87e-07 Helix-turn-helix domains N
chr12 28385792 28399797 PITX2 Transfac.V$PITX2_Q2 28391793 28391803 16.03700 2.45e-07 Helix-turn-helix domains N
chr12 28385792 28399797 PITX2 Transfac.V$PITX2_Q2 28391927 28391937 16.03700 2.45e-07 Helix-turn-helix domains N
chr12 28385792 28399797 PITX2 Transfac.V$PITX2_Q2 28394670 28394680 16.03700 2.45e-07 Helix-turn-helix domains N
chr12 28385792 28399797 PITX2 Transfac.V$PITX2_Q2 28394804 28394814 16.03700 2.45e-07 Helix-turn-helix domains N
chr12 28385792 28399797 POU2F2 Transfac.V$OCT2_01 28389983 28389998 16.91840 6.45e-07 Helix-turn-helix domains N
chr12 28385792 28399797 POU2F2 Homeodomain.UP00191_1 28389983 28389998 16.92660 6.05e-07 Helix-turn-helix domains N
chr12 28385792 28399797 POU2F2 Uniprobe.UP00191_1 28389983 28389998 16.92660 6.05e-07 Helix-turn-helix domains N
chr12 28385792 28399797 POU2F3 Transfac.V$POU2F3_01 28389983 28389998 17.14290 5.71e-07 Helix-turn-helix domains N
chr12 28385792 28399797 POU2F3 Homeodomain.UP00179_1 28389983 28389998 17.02750 6.36e-07 Helix-turn-helix domains N
chr12 28385792 28399797 POU2F3 Uniprobe.UP00179_1 28389983 28389998 17.02750 6.36e-07 Helix-turn-helix domains N
chr12 28385792 28399797 RARA Jolma2013.Rara_DBD_3 28394712 28394726 13.81440 9.48e-07 Zinc-coordinating DNA-binding domains Y
chr12 28385792 28399797 RARG Transfac.V$RARG_01 28391836 28391851 12.15520 7.41e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 RARG Jolma2013.RARG_DBD 28394712 28394728 16.25770 4.58e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 RARG Jolma2013.Rarg_DBD 28394712 28394727 16.51550 3.83e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 RREB1 Transfac.V$RREB1_01 28394510 28394523 17.25930 9.82e-07 Zinc-coordinating DNA-binding domains Y
chr12 28385792 28399797 RUNX1 Transfac.V$EVI1_03 28392776 28392786 19.68540 6.07e-07 Immunoglobulin fold Y
chr12 28385792 28399797 SNAI1 Transfac.V$SNA_Q4 28395235 28395248 16.48150 9.51e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 SOX21 Transfac.V$SOX21_03 28388434 28388449 14.05030 7.24e-07 Other all-alpha-helical DNA-binding domains N
chr12 28385792 28399797 SOX21 Uniprobe.UP00071_1 28388434 28388449 14.03350 7.18e-07 Other all-alpha-helical DNA-binding domains N
chr12 28385792 28399797 SPI1 Transfac.V$PU1_Q4 28388069 28388087 17.68540 2.36e-07 Helix-turn-helix domains N
chr12 28385792 28399797 SPI1 Transfac.V$SPI1_06 28392576 28392589 22.11110 4.46e-08 Helix-turn-helix domains N
chr12 28385792 28399797 SPI1 Jolma2013.SPI1_full 28392576 28392589 22.05150 4.46e-08 Helix-turn-helix domains N
chr12 28385792 28399797 SPIB Transfac.V$SPIB_01 28392573 28392589 21.32580 4.01e-09 Helix-turn-helix domains N
chr12 28385792 28399797 SPIB Transfac.V$SPIB_06 28392576 28392589 20.70450 7.7e-08 Helix-turn-helix domains N
chr12 28385792 28399797 SPIB Jolma2013.SPIB_DBD 28392576 28392589 20.61860 7.7e-08 Helix-turn-helix domains N
chr12 28385792 28399797 SPIC Transfac.V$SPIC_03 28392576 28392589 17.14290 5.01e-07 Helix-turn-helix domains N
chr12 28385792 28399797 SPIC Jolma2013.SPIC_full 28392576 28392589 17.13270 4.91e-07 Helix-turn-helix domains N
chr12 28385792 28399797 SPIC Jolma2013.Spic_DBD 28392576 28392589 21.41240 4.18e-08 Helix-turn-helix domains N
chr12 28385792 28399797 SRF Transfac.V$SRF_06 28393568 28393584 12.82740 9.86e-07 alpha-Helices exposed by beta-structures N
chr12 28385792 28399797 STAT5A Transfac.V$STAT5A_Q6 28396656 28396668 16.70790 8.81e-08 Immunoglobulin fold N
chr12 28385792 28399797 TBX1 Transfac.V$TBX1_04 28393930 28393952 6.96078 9.44e-07 Immunoglobulin fold N
chr12 28385792 28399797 TBX1 Jolma2013.TBX1_DBD_4 28393930 28393952 10.30930 5.94e-07 Immunoglobulin fold N
chr12 28385792 28399797 TBX2 Transfac.V$TBX2_Q2 28394661 28394670 17.70250 6.28e-07 Immunoglobulin fold Y
chr12 28385792 28399797 TFAP2A Transfac.V$TFAP2A_07 28395091 28395103 17.09260 8.69e-07 Basic domains N
chr12 28385792 28399797 TFAP2A JASPAR2014.MA0003.2 28395091 28395105 17.74070 3.88e-07 Basic domains N
chr12 28385792 28399797 TFAP2C JASPAR2014.MA0524.1 28395091 28395105 17.24490 5.74e-07 Basic domains N
chr12 28385792 28399797 TTF1 Transfac.V$TTF1_Q6 28394358 28394369 13.67420 1.97e-07 Helix-turn-helix domains N
chr12 28385792 28399797 VDR Transfac.V$VDR_Q3 28396147 28396161 16.11930 9.43e-07 Zinc-coordinating DNA-binding domains N
chr12 28385792 28399797 ZEB1 Transfac.V$AREB6_01 28392636 28392648 16.37040 2.5e-07 Helix-turn-helix domains N
chr12 28385792 28399797 ZNF143 Transfac.V$STAF_02 28395446 28395466 19.75930 1.23e-07 Zinc-coordinating DNA-binding domains N

The Upstream Pathways of TFs Binding to SE



TF Pathway ID Pathway Name Source
CDK8 pathway0000119 AKT(PKB)-Bad signaling ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ) INOH
CDK8 pathway0000120 AKT(PKB)-Bad signaling ( IL-7 signaling(JAK1 JAK3 STAT5) ) INOH
CDK8 pathway0000483 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Reactome
CDK8 pathway0000484 Constitutive Signaling by NOTCH1 PEST Domain Mutants Reactome
CDK8 pathway0000639 Drosophila Toll-like receptor signaling ( Drosophila Toll-like receptor signaling ) INOH
CDK8 pathway0000905 Generic Transcription Pathway Reactome
CDK8 pathway0000994 Hedgehog NetPath
CDK8 pathway0001524 NOTCH1 Intracellular Domain Regulates Transcription Reactome
CDK8 pathway0001697 Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram ) INOH
CDK8 pathway0001704 PPARA activates gene expression Reactome
CDK8 pathway0002069 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome
CDK8 pathway0002302 Transcriptional regulation of white adipocyte differentiation Reactome
CDK8 pathway0002407 VEGF signaling pathway ( VEGF signaling pathway ) INOH
CDK8 pathway0002806 Hs_Sterol_Regulatory_Element-Binding_Proteins_(SREBP)_signalling_WP1982_90425 WikiPathways
CTCF pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
CTCF pathway0002222 TGF_beta_Receptor NetPath
ERG pathway0000702 ERK cascade ( FGF8 signaling (Mouse) ) INOH
ERG pathway0000703 ERK cascade ( FGF8 signaling (Xenopus) ) INOH
ERG pathway0000781 FGF8 signaling pathway(Mouse) ( FGF8 signaling (Mouse) ) INOH
ERG pathway0000782 FGF8 signaling pathway(Xenopus) ( FGF8 signaling (Xenopus) ) INOH
ERG pathway0001604 PDGF signaling pathway PANTHER
ERG pathway0002743 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways
ETS1 pathway0000177 Angiogenesis PANTHER
ETS1 pathway0000178 Angiopoietin receptor Tie2-mediated signaling PID
ETS1 pathway0000187 AP-1 transcription factor network PID
ETS1 pathway0000271 BCR signaling pathway PID
ETS1 pathway0000335 C-MYB transcription factor network PID
ETS1 pathway0000702 ERK cascade ( FGF8 signaling (Mouse) ) INOH
ETS1 pathway0000703 ERK cascade ( FGF8 signaling (Xenopus) ) INOH
ETS1 pathway0000781 FGF8 signaling pathway(Mouse) ( FGF8 signaling (Mouse) ) INOH
ETS1 pathway0000782 FGF8 signaling pathway(Xenopus) ( FGF8 signaling (Xenopus) ) INOH
ETS1 pathway0001021 HIF-1-alpha transcription factor network PID
ETS1 pathway0001022 HIF-2-alpha transcription factor network PID
ETS1 pathway0001120 IL2 NetPath
ETS1 pathway0001127 IL4-mediated signaling events PID
ETS1 pathway0001128 IL4 NetPath
ETS1 pathway0001543 Oncogene Induced Senescence Reactome
ETS1 pathway0001604 PDGF signaling pathway PANTHER
ETS1 pathway0001805 Ras Pathway PANTHER
ETS1 pathway0002032 Signaling events mediated by focal adhesion kinase PID
ETS1 pathway0002036 Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) PID
ETS1 pathway0002222 TGF_beta_Receptor NetPath
ETS1 pathway0002408 VEGF signaling pathway PANTHER
ETS1 pathway0002588 Dorso-ventral axis formation KEGG
ETS1 pathway0002696 Hs_Apoptosis-related_network_due_to_altered_Notch3_in_ovarian_cancer_WP2864_79278 WikiPathways
ETS1 pathway0002743 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways
ETS1 pathway0002747 Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways
ETS1 pathway0002853 Hs_TGF-beta_Signaling_Pathway_WP366_90028 WikiPathways
ETS1 pathway0002877 Hs_B_Cell_Receptor_Signaling_Pathway_WP23_89900 WikiPathways
FLI1 pathway0000702 ERK cascade ( FGF8 signaling (Mouse) ) INOH
FLI1 pathway0000703 ERK cascade ( FGF8 signaling (Xenopus) ) INOH
FLI1 pathway0000781 FGF8 signaling pathway(Mouse) ( FGF8 signaling (Mouse) ) INOH
FLI1 pathway0000782 FGF8 signaling pathway(Xenopus) ( FGF8 signaling (Xenopus) ) INOH
FLI1 pathway0001604 PDGF signaling pathway PANTHER
ID4 pathway0001078 ID NetPath
ID4 pathway0002591 TGF-beta signaling pathway KEGG
IRF1 pathway0000747 Factors involved in megakaryocyte development and platelet production Reactome
IRF1 pathway0000916 Glucocorticoid receptor regulatory network PID
IRF1 pathway0001079 IFN-gamma pathway PID
IRF1 pathway0001117 IL12 signaling mediated by STAT4 PID
IRF1 pathway0001131 IL6-mediated signaling events PID
IRF1 pathway0001180 Interferon alpha/beta signaling Reactome
IRF1 pathway0001181 Interferon gamma signaling Reactome
IRF1 pathway0001861 Regulation of Telomerase PID
IRF1 pathway0002282 TRAF6 mediated IRF7 activation Reactome
IRF1 pathway0002655 Hepatitis C KEGG
IRF1 pathway0002686 Hs_Tryptophan_metabolism_WP465_85055 WikiPathways
KLF11 pathway0000658 EGFR1 NetPath
KLF11 pathway0002853 Hs_TGF-beta_Signaling_Pathway_WP366_90028 WikiPathways
KLF11 pathway0002877 Hs_B_Cell_Receptor_Signaling_Pathway_WP23_89900 WikiPathways
MAFB pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
MAFB pathway0002841 Hs_Ectoderm_Differentiation_WP2858_89329 WikiPathways
MECOM pathway0001673 PKMTs methylate histone lysines Reactome
MECOM pathway0002562 MAPK signaling pathway KEGG
MECOM pathway0002656 Pathways in cancer KEGG
MECOM pathway0002667 Chronic myeloid leukemia KEGG
MECOM pathway0002755 Hs_White_fat_cell_differentiation_WP3946_90940 WikiPathways
NKX6-1 pathway0001834 Regulation of gene expression in beta cells Reactome
NKX6-1 pathway0001835 Regulation of gene expression in early pancreatic precursor cells Reactome
NKX6-1 pathway0002631 Maturity onset diabetes of the young KEGG
NR2F1 pathway0001534 Nuclear Receptor transcription pathway Reactome
NR2F6 pathway0001534 Nuclear Receptor transcription pathway Reactome
PAX5 pathway0000335 C-MYB transcription factor network PID
PAX5 pathway0001078 ID NetPath
PITX2 pathway0001848 Regulation of nuclear beta catenin signaling and target gene transcription PID
PITX2 pathway0002591 TGF-beta signaling pathway KEGG
PITX2 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
PITX2 pathway0002771 Hs_BMP_Signaling_Pathway_in_Eyelid_Development_WP3927_90735 WikiPathways
POU2F2 pathway0000271 BCR signaling pathway PID
POU2F2 pathway0001921 RNA polymerase II transcribes snRNA genes Reactome
POU2F2 pathway0002393 Validated transcriptional targets of deltaNp63 isoforms PID
RARA pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
RARA pathway0000842 FSH NetPath
RARA pathway0001126 IL3 NetPath
RARA pathway0001534 Nuclear Receptor transcription pathway Reactome
RARA pathway0001883 Retinoic acid receptors-mediated signaling PID
RARA pathway0001947 RXR and RAR heterodimerization with other nuclear receptor PID
RARA pathway0002028 Signaling by Retinoic Acid Reactome
RARA pathway0002656 Pathways in cancer KEGG
RARA pathway0002668 Acute myeloid leukemia KEGG
RARA pathway0002686 Hs_Tryptophan_metabolism_WP465_85055 WikiPathways
RARG pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
RARG pathway0001534 Nuclear Receptor transcription pathway Reactome
RARG pathway0001883 Retinoic acid receptors-mediated signaling PID
RARG pathway0001947 RXR and RAR heterodimerization with other nuclear receptor PID
RARG pathway0002028 Signaling by Retinoic Acid Reactome
RUNX1 pathway0000176 AndrogenReceptor NetPath
RUNX1 pathway0001551 Organic cation transport Reactome
RUNX1 pathway0001799 RANKL NetPath
RUNX1 pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
RUNX1 pathway0002222 TGF_beta_Receptor NetPath
RUNX1 pathway0002393 Validated transcriptional targets of deltaNp63 isoforms PID
RUNX1 pathway0002656 Pathways in cancer KEGG
RUNX1 pathway0002667 Chronic myeloid leukemia KEGG
RUNX1 pathway0002668 Acute myeloid leukemia KEGG
SNAI1 pathway0001170 Integrin-linked kinase signaling PID
SNAI1 pathway0002036 Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) PID
SNAI1 pathway0002390 Validated targets of C-MYC transcriptional activation PID
SNAI1 pathway0002597 Adherens junction KEGG
SNAI1 pathway0002826 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 WikiPathways
SPI1 pathway0000335 C-MYB transcription factor network PID
SPI1 pathway0000702 ERK cascade ( FGF8 signaling (Mouse) ) INOH
SPI1 pathway0000703 ERK cascade ( FGF8 signaling (Xenopus) ) INOH
SPI1 pathway0000781 FGF8 signaling pathway(Mouse) ( FGF8 signaling (Mouse) ) INOH
SPI1 pathway0000782 FGF8 signaling pathway(Xenopus) ( FGF8 signaling (Xenopus) ) INOH
SPI1 pathway0000916 Glucocorticoid receptor regulatory network PID
SPI1 pathway0001127 IL4-mediated signaling events PID
SPI1 pathway0001128 IL4 NetPath
SPI1 pathway0001191 Interleukin signaling pathway PANTHER
SPI1 pathway0001799 RANKL NetPath
SPI1 pathway0001857 Regulation of retinoblastoma protein PID
SPI1 pathway0002391 Validated targets of C-MYC transcriptional repression PID
SPI1 pathway0002656 Pathways in cancer KEGG
SPI1 pathway0002668 Acute myeloid leukemia KEGG
SPI1 pathway0002874 Hs_RANKL-RANK_(Receptor_activator_of_NFKB_(ligand))_Signaling_Pathway_WP2018_90016 WikiPathways
SPIC pathway0001191 Interleukin signaling pathway PANTHER
SRF pathway0000492 Coregulation of Androgen receptor activity PID
SRF pathway0000692 ErbB1 downstream signaling PID
SRF pathway0001191 Interleukin signaling pathway PANTHER
SRF pathway0001572 p38 MAPK pathway PANTHER
SRF pathway0001574 p38 signaling mediated by MAPKAP kinases PID
SRF pathway0001604 PDGF signaling pathway PANTHER
SRF pathway0001605 PDGFR-alpha signaling pathway PID
SRF pathway0001606 PDGFR-beta signaling pathway PID
SRF pathway0001805 Ras Pathway PANTHER
SRF pathway0001894 RHO GTPases Activate Formins Reactome
SRF pathway0001903 RhoA signaling pathway PID
SRF pathway0002034 Signaling events mediated by HDAC Class II PID
SRF pathway0002340 Trk receptor signaling mediated by the MAPK pathway PID
SRF pathway0002562 MAPK signaling pathway KEGG
SRF pathway0002743 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways
SRF pathway0002750 Hs_Serotonin_Receptor_4-6-7_and_NR3C_Signaling_WP734_74438 WikiPathways
SRF pathway0002826 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 WikiPathways
SRF pathway0002834 Hs_Serotonin_Receptor_2_and_ELK-SRF-GATA4_signaling_WP732_80010 WikiPathways
STAT1 pathway0000177 Angiogenesis PANTHER
STAT1 pathway0000270 BCR NetPath
STAT1 pathway0000513 CXCR4-mediated signaling events PID
STAT1 pathway0000633 Downstream signal transduction Reactome
STAT1 pathway0000652 EGF receptor signaling pathway PANTHER
STAT1 pathway0000658 EGFR1 NetPath
STAT1 pathway0000687 EPO signaling pathway PID
STAT1 pathway0000688 EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ) INOH
STAT1 pathway0000692 ErbB1 downstream signaling PID
STAT1 pathway0000780 FGF signaling pathway PID
STAT1 pathway0000899 Gene expression of SOCS by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0000900 Gene expression of SOCS1 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0000901 Gene expression of SOCS3 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0000916 Glucocorticoid receptor regulatory network PID
STAT1 pathway0000966 GMCSF-mediated signaling events PID
STAT1 pathway0000976 Growth hormone receptor signaling Reactome
STAT1 pathway0001079 IFN-gamma pathway PID
STAT1 pathway0001080 IFN alpha signaling pathway((JAK1 TYK2 STAT1 STAT2) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) ) INOH
STAT1 pathway0001081 IFN alpha signaling pathway(JAK1 TYK2 STAT1 STAT3) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) ) INOH
STAT1 pathway0001082 IFN alpha signaling pathway(JAK1 TYK2 STAT1) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) ) INOH
STAT1 pathway0001084 IFN gamma signaling pathway(JAK1 JAK2 STAT1) ( IFN gamma signaling(JAK1 JAK2 STAT1) ) INOH
STAT1 pathway0001109 IL-5 signaling pathway(JAK1 JAK2 STAT1 STAT5) ( IL-5 signaling(JAK1 JAK2 STAT1 STAT5) ) INOH
STAT1 pathway0001112 IL-7 NetPath
STAT1 pathway0001116 IL12-mediated signaling events PID
STAT1 pathway0001119 IL2-mediated signaling events PID
STAT1 pathway0001120 IL2 NetPath
STAT1 pathway0001123 IL23-mediated signaling events PID
STAT1 pathway0001124 IL27-mediated signaling events PID
STAT1 pathway0001128 IL4 NetPath
STAT1 pathway0001130 IL5 NetPath
STAT1 pathway0001131 IL6-mediated signaling events PID
STAT1 pathway0001132 IL6 NetPath
STAT1 pathway0001135 IL9 NetPath
STAT1 pathway0001179 Interferon-gamma signaling pathway PANTHER
STAT1 pathway0001180 Interferon alpha/beta signaling Reactome
STAT1 pathway0001181 Interferon gamma signaling Reactome
STAT1 pathway0001188 Interleukin-6 signaling Reactome
STAT1 pathway0001191 Interleukin signaling pathway PANTHER
STAT1 pathway0001219 ISG15 antiviral mechanism Reactome
STAT1 pathway0001226 JAK-STAT pathway and regulation pathway ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0001228 JAK/STAT signaling pathway PANTHER
STAT1 pathway0001246 KitReceptor NetPath
STAT1 pathway0001264 Leptin NetPath
STAT1 pathway0001560 Oxidative stress response PANTHER
STAT1 pathway0001604 PDGF signaling pathway PANTHER
STAT1 pathway0001606 PDGFR-beta signaling pathway PID
STAT1 pathway0001697 Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0001727 Prolactin NetPath
STAT1 pathway0001799 RANKL NetPath
STAT1 pathway0001805 Ras Pathway PANTHER
STAT1 pathway0001840 Regulation of IFNA signaling Reactome
STAT1 pathway0001841 Regulation of IFNG signaling Reactome
STAT1 pathway0002000 SHP2 signaling PID
STAT1 pathway0002010 Signaling by cytosolic FGFR1 fusion mutants Reactome
STAT1 pathway0002030 Signaling by SCF-KIT Reactome
STAT1 pathway0002039 Signaling events mediated by Stem cell factor receptor (c-Kit) PID
STAT1 pathway0002040 Signaling events mediated by TCPTP PID
STAT1 pathway0002199 TCR NetPath
STAT1 pathway0002246 TNF receptor signaling pathway PID
STAT1 pathway0002249 TNFalpha NetPath
STAT1 pathway0002354 TSH NetPath
STAT1 pathway0002355 TSLP NetPath
STAT1 pathway0002568 Chemokine signaling pathway KEGG
STAT1 pathway0002602 Toll-like receptor signaling pathway KEGG
STAT1 pathway0002606 Jak-STAT signaling pathway KEGG
STAT1 pathway0002649 Leishmaniasis KEGG
STAT1 pathway0002652 Toxoplasmosis KEGG
STAT1 pathway0002655 Hepatitis C KEGG
STAT1 pathway0002656 Pathways in cancer KEGG
STAT1 pathway0002659 Pancreatic cancer KEGG
STAT1 pathway0002682 Hs_Interferon_type_I_signaling_pathways_WP585_85198 WikiPathways
STAT1 pathway0002689 Hs_Cytokines_and_Inflammatory_Response_WP530_79331 WikiPathways
STAT1 pathway0002712 Hs_Leptin_signaling_pathway_WP2034_89856 WikiPathways
STAT1 pathway0002718 Hs_Interleukin-11_Signaling_Pathway_WP2332_79525 WikiPathways
STAT1 pathway0002725 Hs_Endochondral_Ossification_WP474_87977 WikiPathways
STAT1 pathway0002731 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 WikiPathways
STAT1 pathway0002735 Hs_PDGF_Pathway_WP2526_82681 WikiPathways
STAT1 pathway0002740 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways
STAT1 pathway0002743 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways
STAT1 pathway0002751 Hs_Integrated_Cancer_Pathway_WP1971_82939 WikiPathways
STAT1 pathway0002760 Hs_Oncostatin_M_Signaling_Pathway_WP2374_73668 WikiPathways
STAT1 pathway0002813 Hs_One_carbon_metabolism_and_related_pathways_WP3940_91096 WikiPathways
STAT1 pathway0002829 Hs_Kit_receptor_signaling_pathway_WP304_78799 WikiPathways
STAT1 pathway0002837 Hs_IL-5_Signaling_Pathway_WP127_78498 WikiPathways
STAT1 pathway0002844 Hs_IL-2_Signaling_Pathway_WP49_91243 WikiPathways
STAT1 pathway0002858 Hs_IL-6_signaling_pathway_WP364_89832 WikiPathways
STAT1 pathway0002860 Hs_Prolactin_Signaling_Pathway_WP2037_90015 WikiPathways
STAT1 pathway0002864 Hs_IL-4_Signaling_Pathway_WP395_89828 WikiPathways
STAT1 pathway0002865 Hs_Brain-Derived_Neurotrophic_Factor_(BDNF)_signaling_pathway_WP2380_89803 WikiPathways
STAT1 pathway0002866 Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 WikiPathways
STAT1 pathway0002879 Hs_IL-9_Signaling_Pathway_WP22_79264 WikiPathways
STAT1 pathway0002880 Hs_Insulin_signalling_in_adipocytes_(diabetic_condition)_WP3635_86059 WikiPathways
STAT1 pathway0002881 Hs_Insulin_signalling_in_adipocytes_(normal_condition)_WP3634_86060 WikiPathways
STAT5A pathway0000178 Angiopoietin receptor Tie2-mediated signaling PID
STAT5A pathway0000388 CD40/CD40L signaling PID
STAT5A pathway0000513 CXCR4-mediated signaling events PID
STAT5A pathway0000633 Downstream signal transduction Reactome
STAT5A pathway0000652 EGF receptor signaling pathway PANTHER
STAT5A pathway0000658 EGFR1 NetPath
STAT5A pathway0000687 EPO signaling pathway PID
STAT5A pathway0000688 EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ) INOH
STAT5A pathway0000696 ErbB4 signaling events PID
STAT5A pathway0000899 Gene expression of SOCS by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT5A pathway0000900 Gene expression of SOCS1 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT5A pathway0000901 Gene expression of SOCS3 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT5A pathway0000916 Glucocorticoid receptor regulatory network PID
STAT5A pathway0000966 GMCSF-mediated signaling events PID
STAT5A pathway0000976 Growth hormone receptor signaling Reactome
STAT5A pathway0000977 Growth hormone signaling pathway(JAK2 STAT5) ( Growth hormone signaling(JAK2 STAT5) ) INOH
STAT5A pathway0001105 IL-2 signaling pathway(JAK1 JAK3 STAT5) ( IL-2 signaling(JAK1 JAK3 STAT5) ) INOH
STAT5A pathway0001107 IL-3 signaling pathway(JAK1 JAK2 STAT5) ( IL-3 signaling(JAK1 JAK2 STAT5) ) INOH
STAT5A pathway0001109 IL-5 signaling pathway(JAK1 JAK2 STAT1 STAT5) ( IL-5 signaling(JAK1 JAK2 STAT1 STAT5) ) INOH
STAT5A pathway0001112 IL-7 NetPath
STAT5A pathway0001113 IL-7 signaling pathway(JAK1 JAK3 STAT5) ( IL-7 signaling(JAK1 JAK3 STAT5) ) INOH
STAT5A pathway0001116 IL12-mediated signaling events PID
STAT5A pathway0001119 IL2-mediated signaling events PID
STAT5A pathway0001120 IL2 NetPath
STAT5A pathway0001122 IL2 signaling events mediated by STAT5 PID
STAT5A pathway0001123 IL23-mediated signaling events PID
STAT5A pathway0001124 IL27-mediated signaling events PID
STAT5A pathway0001125 IL3-mediated signaling events PID
STAT5A pathway0001126 IL3 NetPath
STAT5A pathway0001127 IL4-mediated signaling events PID
STAT5A pathway0001128 IL4 NetPath
STAT5A pathway0001129 IL5-mediated signaling events PID
STAT5A pathway0001130 IL5 NetPath
STAT5A pathway0001132 IL6 NetPath
STAT5A pathway0001135 IL9 NetPath
STAT5A pathway0001186 Interleukin-2 signaling Reactome
STAT5A pathway0001187 Interleukin-3, 5 and GM-CSF signaling Reactome
STAT5A pathway0001189 Interleukin-7 signaling Reactome
STAT5A pathway0001191 Interleukin signaling pathway PANTHER
STAT5A pathway0001226 JAK-STAT pathway and regulation pathway ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT5A pathway0001228 JAK/STAT signaling pathway PANTHER
STAT5A pathway0001246 KitReceptor NetPath
STAT5A pathway0001264 Leptin NetPath
STAT5A pathway0001535 Nuclear signaling by ERBB4 Reactome
STAT5A pathway0001603 PDGF signaling pathway (Mammal) ( PDGF signaling pathway ) INOH
STAT5A pathway0001604 PDGF signaling pathway PANTHER
STAT5A pathway0001606 PDGFR-beta signaling pathway PID
STAT5A pathway0001697 Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT5A pathway0001727 Prolactin NetPath
STAT5A pathway0001728 Prolactin receptor signaling Reactome
STAT5A pathway0001788 RAC1 signaling pathway PID
STAT5A pathway0002010 Signaling by cytosolic FGFR1 fusion mutants Reactome
STAT5A pathway0002022 Signaling by Leptin Reactome
STAT5A pathway0002030 Signaling by SCF-KIT Reactome
STAT5A pathway0002038 Signaling events mediated by PTP1B PID
STAT5A pathway0002039 Signaling events mediated by Stem cell factor receptor (c-Kit) PID
STAT5A pathway0002040 Signaling events mediated by TCPTP PID
STAT5A pathway0002199 TCR NetPath
STAT5A pathway0002249 TNFalpha NetPath
STAT5A pathway0002339 Trk receptor signaling mediated by PI3K and PLC-gamma PID
STAT5A pathway0002355 TSLP NetPath
STAT5A pathway0002388 Validated nuclear estrogen receptor alpha network PID
STAT5A pathway0002564 ErbB signaling pathway KEGG
STAT5A pathway0002606 Jak-STAT signaling pathway KEGG
STAT5A pathway0002656 Pathways in cancer KEGG
STAT5A pathway0002667 Chronic myeloid leukemia KEGG
STAT5A pathway0002668 Acute myeloid leukemia KEGG
STAT5A pathway0002682 Hs_Interferon_type_I_signaling_pathways_WP585_85198 WikiPathways
STAT5A pathway0002686 Hs_Tryptophan_metabolism_WP465_85055 WikiPathways
STAT5A pathway0002688 Hs_TYROBP_Causal_Network_WP3945_90843 WikiPathways
STAT5A pathway0002690 Hs_ErbB_Signaling_Pathway_WP673_91869 WikiPathways
STAT5A pathway0002701 Hs_Association_Between_Physico-Chemical_Features_and_Toxicity_Associated_Pathways_WP3680_90113 WikiPathways
STAT5A pathway0002737 Hs_Regulation_of_Actin_Cytoskeleton_WP51_79977 WikiPathways
STAT5A pathway0002775 Hs_Bladder_Cancer_WP2828_89143 WikiPathways
STAT5A pathway0002829 Hs_Kit_receptor_signaling_pathway_WP304_78799 WikiPathways
STAT5A pathway0002837 Hs_IL-5_Signaling_Pathway_WP127_78498 WikiPathways
STAT5A pathway0002844 Hs_IL-2_Signaling_Pathway_WP49_91243 WikiPathways
STAT5A pathway0002860 Hs_Prolactin_Signaling_Pathway_WP2037_90015 WikiPathways
STAT5A pathway0002862 Hs_AGE-RAGE_pathway_WP2324_89798 WikiPathways
STAT5A pathway0002864 Hs_IL-4_Signaling_Pathway_WP395_89828 WikiPathways
STAT5A pathway0002866 Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 WikiPathways
STAT5A pathway0002871 Hs_IL-3_Signaling_Pathway_WP286_78583 WikiPathways
STAT5A pathway0002872 Hs_IL-7_Signaling_Pathway_WP205_89854 WikiPathways
TBX1 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
TBX1 pathway0002826 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 WikiPathways
TBX2 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
TFAP2A pathway0000377 Caspase Cascade in Apoptosis PID
TFAP2A pathway0002699 Hs_Corticotropin-releasing_hormone_signaling_pathway_WP2355_90017 WikiPathways
TFAP2A pathway0002747 Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways
TFAP2A pathway0002841 Hs_Ectoderm_Differentiation_WP2858_89329 WikiPathways
TFAP2A pathway0002849 Hs_Hypothetical_Craniofacial_Development_Pathway_WP3655_88473 WikiPathways
TFAP2C pathway0002394 Validated transcriptional targets of TAp63 isoforms PID
TTF1 pathway0000078 Activation of rRNA Expression by ERCC6 (CSB) and EHMT2 (G9a) Reactome
TTF1 pathway0000902 General transcription by RNA polymerase I PANTHER
TTF1 pathway0001512 NoRC negatively regulates rRNA expression Reactome
TTF1 pathway0001916 RNA Polymerase I Transcription Initiation Reactome
TTF1 pathway0001917 RNA Polymerase I Transcription Termination Reactome
TTF1 pathway0002140 Surfactant metabolism Reactome
VDR pathway0000608 Direct p53 effectors PID
VDR pathway0001534 Nuclear Receptor transcription pathway Reactome
VDR pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
VDR pathway0001883 Retinoic acid receptors-mediated signaling PID
VDR pathway0001947 RXR and RAR heterodimerization with other nuclear receptor PID
VDR pathway0002222 TGF_beta_Receptor NetPath
VDR pathway0002393 Validated transcriptional targets of deltaNp63 isoforms PID
VDR pathway0002394 Validated transcriptional targets of TAp63 isoforms PID
VDR pathway0002431 Vitamin D metabolism and pathway PANTHER
VDR pathway0002685 Hs_Drug_Induction_of_Bile_Acid_Pathway_WP2289_88593 WikiPathways
ZEB1 pathway0001170 Integrin-linked kinase signaling PID
ZEB1 pathway0002222 TGF_beta_Receptor NetPath
ZNF143 pathway0001921 RNA polymerase II transcribes snRNA genes Reactome
ZNF143 pathway0001926 RNA Polymerase III Abortive And Retractive Initiation Reactome
ZNF143 pathway0001930 RNA Polymerase III Transcription Initiation From Type 3 Promoter Reactome