General Details

Super-enhancer:SE_02_33600562
Genomic Locus: chr1: 182891157-182905460
Size/Length:14303bp
Conservation:0.0436851
BioSample Type:Cell line
Tissue Type:Haematopoietic and lymphoid tissue
Sample Name:SET2
Source:NCBI GEO/SRA
Element:1
Rank:562
ChIP Density(Case):15378.5856
ChIP Density(Input):2347.1223

Super-enhancer Associated Network


* The complex regulatory networks formed by this SE , SE associated genes , TFs binding to the SE and their upstream pathways can be interactively visualized.


Fimo:
SE-Gene Linking Strategies:
Pathway Enriciment Threshold:
Top Pathway:
 



Super-enhancer Associated Statistics

Associated Gene Details

ROSE Overlap:C1orf14
ROSE Proximal:.
ROSE Closest:C1orf14
The Closest Active:DHX9

Factors Binding to Super-enhancer




Using these SE element regions to analyze by online tools GREAT *The TFs binding to this SE identified by ChIP-seq.

Chrome Element_Start Element_End TF TF Source TF_Start TF_End TF Class Master TF
chr1 182891157 182905460 CDK8 Remap_0281 182898331 182899682 TcoF-DB_TcoF N
chr1 182891157 182905460 STAT1 ChIP-Atlas_1201 182899471 182899649 Immunoglobulin fold N
chr1 182891157 182905460 STAT1 ChIP-Atlas_1205 182898921 182899579 Immunoglobulin fold N
chr1 182891157 182905460 STAT1 ChIP-Atlas_1206 182898980 182899578 Immunoglobulin fold N

Using these SE element regions to analyze by online tools GREAT * The TFs binding to this SE predicted by Motif.

Chrome Element_Start Element_End TF Database TF_Start TF_End Score P_Value TF Class Master TF
chr1 182891157 182905460 ALX4 Transfac.V$ALX4_06 182898909 182898921 15.01960 6.36e-07 Helix-turn-helix domains N
chr1 182891157 182905460 ALX4 Jolma2013.Alx4_DBD 182898909 182898921 14.96460 6.36e-07 Helix-turn-helix domains N
chr1 182891157 182905460 ARX Transfac.V$ARX_03 182898909 182898921 15.61400 4.21e-07 Helix-turn-helix domains N
chr1 182891157 182905460 ARX Transfac.V$ARX_04 182898909 182898921 15.97350 3.02e-07 Helix-turn-helix domains N
chr1 182891157 182905460 ARX Jolma2013.ARX_DBD 182898909 182898921 15.55470 4.21e-07 Helix-turn-helix domains N
chr1 182891157 182905460 ARX Jolma2013.Arx_DBD 182898909 182898921 15.89840 3.53e-07 Helix-turn-helix domains N
chr1 182891157 182905460 ATF5 Transfac.V$ATF5_01 182901049 182901059 18.08990 1.81e-07 Basic domains N
chr1 182891157 182905460 BCL6B Transfac.V$BCL6B_03 182901574 182901589 16.28170 7.03e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 BCL6B Uniprobe.UP00043_1 182901574 182901589 16.24650 7.02e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 BDP1 Transfac.V$BDP1_01 182902254 182902265 16.44550 7.01e-07 ENCODE_TF N
chr1 182891157 182905460 DLX4 Transfac.V$DLX7_01 182901433 182901449 15.87250 8.15e-07 Helix-turn-helix domains N
chr1 182891157 182905460 DLX4 Homeodomain.UP00110_1 182901433 182901449 15.95580 7.2e-07 Helix-turn-helix domains N
chr1 182891157 182905460 DLX4 Uniprobe.UP00110_1 182901433 182901449 15.95580 7.2e-07 Helix-turn-helix domains N
chr1 182891157 182905460 EGR1 JASPAR2014.MA0162.2 182894251 182894264 17.19610 9.07e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 FOXG1 Jolma2013.Foxg1_DBD 182895573 182895589 12.01030 9.89e-07 Helix-turn-helix domains N
chr1 182891157 182905460 FOXP1 Transfac.V$FOXP1_01 182893373 182893392 14.59520 1.19e-07 Helix-turn-helix domains N
chr1 182891157 182905460 FOXP1 Transfac.V$FOXP1_01 182899853 182899872 10.75000 3.49e-07 Helix-turn-helix domains N
chr1 182891157 182905460 FOXP1 Transfac.V$FOXP1_01 182905258 182905277 7.03571 8.09e-07 Helix-turn-helix domains N
chr1 182891157 182905460 FOXP1 Transfac.V$FOXP1_01 182905262 182905281 6.51190 9.82e-07 Helix-turn-helix domains N
chr1 182891157 182905460 HBP1 Transfac.V$HBP1_04 182895858 182895874 15.92410 4.28e-07 Other all-alpha-helical DNA-binding domains N
chr1 182891157 182905460 HBP1 Uniprobe.UP00055_2 182895858 182895874 15.84120 4.46e-07 Other all-alpha-helical DNA-binding domains N
chr1 182891157 182905460 HNF1B Transfac.V$HNF1B_04 182895905 182895916 17.55450 6.69e-07 Helix-turn-helix domains N
chr1 182891157 182905460 HNF1B JASPAR2014.MA0153.1 182895905 182895916 17.55450 6.69e-07 Helix-turn-helix domains N
chr1 182891157 182905460 IRF8 Jolma2013.IRF8_DBD 182892316 182892329 18.25770 4.95e-07 Helix-turn-helix domains N
chr1 182891157 182905460 MAFK JASPAR2014.MA0496.1 182900312 182900326 16.52270 8.84e-07 Basic domains N
chr1 182891157 182905460 MEIS1 Transfac.V$MEIS1_02 182901231 182901246 17.38140 8.98e-07 Helix-turn-helix domains N
chr1 182891157 182905460 MEIS1 Homeodomain.UP00186_1 182901231 182901246 17.41240 8.48e-07 Helix-turn-helix domains N
chr1 182891157 182905460 MEIS1 Uniprobe.UP00186_1 182901231 182901246 17.41240 8.48e-07 Helix-turn-helix domains N
chr1 182891157 182905460 MEIS2 Transfac.V$MEIS2_01 182901231 182901246 17.61860 6.22e-07 Helix-turn-helix domains N
chr1 182891157 182905460 MEIS3 Transfac.V$MRG2_01 182901231 182901246 18.11340 1.35e-07 Helix-turn-helix domains N
chr1 182891157 182905460 MYEF2 Transfac.V$MMEF2_Q6 182900501 182900516 17.05310 4.91e-07 alpha-Helices exposed by beta-structures N
chr1 182891157 182905460 NR2F6 Jolma2013.Nr2f6_DBD 182901848 182901862 16.78350 2.69e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ONECUT1 Transfac.V$HNF6_Q6 182892722 182892733 16.60820 4.11e-07 Helix-turn-helix domains N
chr1 182891157 182905460 ONECUT1 Jolma2013.ONECUT1_DBD 182892721 182892734 17.45360 4.31e-07 Helix-turn-helix domains N
chr1 182891157 182905460 ONECUT2 Transfac.V$ONECUT2_01 182892721 182892734 17.08620 8.02e-07 Helix-turn-helix domains N
chr1 182891157 182905460 ONECUT2 Jolma2013.ONECUT2_DBD 182892721 182892734 17.04120 8.1e-07 Helix-turn-helix domains N
chr1 182891157 182905460 ONECUT3 Transfac.V$ONECUT3_01 182892721 182892734 18.78650 1.87e-07 Helix-turn-helix domains N
chr1 182891157 182905460 ONECUT3 Jolma2013.ONECUT3_DBD 182892721 182892734 18.75260 1.87e-07 Helix-turn-helix domains N
chr1 182891157 182905460 OTP Transfac.V$OTP_01 182900402 182900418 17.35290 5.19e-07 Helix-turn-helix domains N
chr1 182891157 182905460 OTP Homeodomain.UP00237_1 182900402 182900418 17.27450 5.61e-07 Helix-turn-helix domains N
chr1 182891157 182905460 OTP Uniprobe.UP00237_1 182900402 182900418 17.27450 5.61e-07 Helix-turn-helix domains N
chr1 182891157 182905460 PITX2 Transfac.V$PITX2_Q2 182893696 182893706 16.03700 2.45e-07 Helix-turn-helix domains N
chr1 182891157 182905460 PITX2 Transfac.V$PITX2_Q2 182896548 182896558 16.03700 2.45e-07 Helix-turn-helix domains N
chr1 182891157 182905460 PITX2 Transfac.V$PITX2_Q2 182901895 182901905 16.03700 2.45e-07 Helix-turn-helix domains N
chr1 182891157 182905460 PITX2 Transfac.V$PITX2_Q2 182902304 182902314 16.03700 2.45e-07 Helix-turn-helix domains N
chr1 182891157 182905460 PITX2 Transfac.V$PITX2_Q2 182905401 182905411 16.03700 2.45e-07 Helix-turn-helix domains N
chr1 182891157 182905460 PKNOX1 Transfac.V$PREP1_01 182901231 182901246 19.45360 8.7e-08 Helix-turn-helix domains N
chr1 182891157 182905460 PKNOX1 Homeodomain.UP00203_1 182901231 182901246 19.43300 8.89e-08 Helix-turn-helix domains N
chr1 182891157 182905460 PKNOX1 Uniprobe.UP00203_1 182901231 182901246 19.43300 8.89e-08 Helix-turn-helix domains N
chr1 182891157 182905460 POLR3A Transfac.V$RPC155_01 182891475 182891490 21.24770 2.73e-08 ENCODE_TF N
chr1 182891157 182905460 POLR3A Transfac.V$RPC155_01 182896593 182896608 21.07340 3.25e-08 ENCODE_TF N
chr1 182891157 182905460 POLR3A Transfac.V$RPC155_01 182900074 182900089 21.57800 1.88e-08 ENCODE_TF N
chr1 182891157 182905460 POLR3A Transfac.V$RPC155_01 182901843 182901858 16.88990 9.91e-07 ENCODE_TF N
chr1 182891157 182905460 POLR3A Transfac.V$RPC155_01 182902254 182902269 24.47710 4.33e-10 ENCODE_TF N
chr1 182891157 182905460 PRRX1 Homeodomain.UP00266_1 182900401 182900417 17.71570 2.79e-07 Helix-turn-helix domains N
chr1 182891157 182905460 PRRX1 Homeodomain.UP00266_1 182900402 182900418 16.89220 7.29e-07 Helix-turn-helix domains N
chr1 182891157 182905460 PRRX1 Uniprobe.UP00266_1 182900401 182900417 17.71570 2.79e-07 Helix-turn-helix domains N
chr1 182891157 182905460 PRRX1 Uniprobe.UP00266_1 182900402 182900418 16.89220 7.29e-07 Helix-turn-helix domains N
chr1 182891157 182905460 RARG Jolma2013.Rarg_DBD 182901847 182901862 16.08250 4.63e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 SOX14 Transfac.V$SOX14_07 182901259 182901273 16.72310 8.66e-07 Other all-alpha-helical DNA-binding domains N
chr1 182891157 182905460 SOX15 Transfac.V$SOX15_07 182901259 182901273 9.55385 9.12e-07 Other all-alpha-helical DNA-binding domains N
chr1 182891157 182905460 SOX2 Transfac.V$SOX2_05 182901259 182901273 16.21310 9.96e-07 Other all-alpha-helical DNA-binding domains N
chr1 182891157 182905460 SP2 JASPAR2014.MA0516.1 182896728 182896742 17.08620 9.62e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 SPDEF Transfac.V$SPDEF_07 182904846 182904861 17.70690 6.23e-07 Helix-turn-helix domains N
chr1 182891157 182905460 SPDEF Jolma2013.SPDEF_full_3 182904846 182904861 17.74490 6.13e-07 Helix-turn-helix domains N
chr1 182891157 182905460 SPI1 Transfac.V$PU1_Q4 182895183 182895201 18.24720 1.16e-07 Helix-turn-helix domains N
chr1 182891157 182905460 SRY Transfac.V$SRY_11 182901260 182901272 16.67690 6.88e-07 Other all-alpha-helical DNA-binding domains N
chr1 182891157 182905460 TBP Transfac.V$TBP_06 182896183 182896198 13.62350 6.39e-07 beta-Sheet binding to DNA N
chr1 182891157 182905460 TBX18 Transfac.V$TBX18_01 182902987 182903005 3.80412 8.49e-07 Immunoglobulin fold N
chr1 182891157 182905460 TBX2 Transfac.V$TBX2_Q2 182893706 182893715 17.70250 6.28e-07 Immunoglobulin fold Y
chr1 182891157 182905460 TBX20 Transfac.V$TBX20_02 182902684 182902699 17.40000 4.94e-07 Immunoglobulin fold N
chr1 182891157 182905460 TCF7L2 Transfac.V$TCF7L2_04 182902768 182902783 15.36620 8.56e-07 Other all-alpha-helical DNA-binding domains N
chr1 182891157 182905460 TCF7L2 Uniprobe.UP00083_2 182902768 182902783 15.36620 8.38e-07 Other all-alpha-helical DNA-binding domains N
chr1 182891157 182905460 TP63 JASPAR2014.MA0525.1 182891545 182891564 16.84310 9.84e-07 Immunoglobulin fold N
chr1 182891157 182905460 VSX1 Transfac.V$VSX1_01 182900402 182900418 16.19610 9.01e-07 Helix-turn-helix domains N
chr1 182891157 182905460 VSX1 Homeodomain.UP00141_1 182900402 182900418 16.17650 9.06e-07 Helix-turn-helix domains N
chr1 182891157 182905460 VSX1 Uniprobe.UP00141_1 182900402 182900418 16.17650 9.06e-07 Helix-turn-helix domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893931 182893951 18.61220 2.53e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893935 182893955 19.59180 1.19e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893939 182893959 19.75510 1.04e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893943 182893963 20.32650 6.57e-08 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893947 182893967 19.10200 1.74e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893963 182893983 20.85710 4.22e-08 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893964 182893984 19.14290 1.68e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893967 182893987 24.81630 9.86e-10 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893971 182893991 24.73470 1.08e-09 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893974 182893994 24.20410 1.89e-09 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893975 182893995 18.24490 3.32e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893979 182893999 18.10200 3.69e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893983 182894003 20.89800 4.08e-08 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893986 182894006 20.02040 8.44e-08 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893990 182894010 18.28570 3.22e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893994 182894014 19.59180 1.19e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182893998 182894018 16.75510 9.59e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894049 182894069 17.38780 6.17e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894053 182894073 19.87760 9.47e-08 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894057 182894077 17.57140 5.41e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894115 182894135 18.04080 3.85e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894119 182894139 19.22450 1.58e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894131 182894151 20.18370 7.39e-08 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894140 182894160 18.83670 2.13e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894143 182894163 23.34690 4.43e-09 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894149 182894169 24.55100 1.31e-09 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894152 182894172 23.30610 4.61e-09 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894153 182894173 16.87760 8.81e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894158 182894178 22.95920 6.46e-09 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894161 182894181 21.24490 3.04e-08 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894170 182894190 18.00000 3.97e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894185 182894205 18.89800 2.03e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894188 182894208 19.59180 1.19e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894194 182894214 17.20410 7.02e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894197 182894217 17.28570 6.63e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894245 182894265 21.10200 3.43e-08 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182894248 182894268 26.87760 9.01e-11 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182895173 182895193 19.46940 1.31e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF263 JASPAR2014.MA0528.1 182899437 182899457 17.12240 7.43e-07 Zinc-coordinating DNA-binding domains N
chr1 182891157 182905460 ZNF35 Transfac.V$ZFP105_03 182905252 182905266 13.83780 9.25e-07 Zinc-coordinating DNA-binding domains N

The Upstream Pathways of TFs Binding to SE



TF Pathway ID Pathway Name Source
ATF5 pathway0002037 Signaling events mediated by PRL PID
BDP1 pathway0001926 RNA Polymerase III Abortive And Retractive Initiation Reactome
BDP1 pathway0001928 RNA Polymerase III Transcription Initiation From Type 1 Promoter Reactome
BDP1 pathway0001929 RNA Polymerase III Transcription Initiation From Type 2 Promoter Reactome
BDP1 pathway0001930 RNA Polymerase III Transcription Initiation From Type 3 Promoter Reactome
CDK8 pathway0000119 AKT(PKB)-Bad signaling ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ) INOH
CDK8 pathway0000120 AKT(PKB)-Bad signaling ( IL-7 signaling(JAK1 JAK3 STAT5) ) INOH
CDK8 pathway0000483 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Reactome
CDK8 pathway0000484 Constitutive Signaling by NOTCH1 PEST Domain Mutants Reactome
CDK8 pathway0000639 Drosophila Toll-like receptor signaling ( Drosophila Toll-like receptor signaling ) INOH
CDK8 pathway0000905 Generic Transcription Pathway Reactome
CDK8 pathway0000994 Hedgehog NetPath
CDK8 pathway0001524 NOTCH1 Intracellular Domain Regulates Transcription Reactome
CDK8 pathway0001697 Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram ) INOH
CDK8 pathway0001704 PPARA activates gene expression Reactome
CDK8 pathway0002069 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome
CDK8 pathway0002302 Transcriptional regulation of white adipocyte differentiation Reactome
CDK8 pathway0002407 VEGF signaling pathway ( VEGF signaling pathway ) INOH
CDK8 pathway0002806 Hs_Sterol_Regulatory_Element-Binding_Proteins_(SREBP)_signalling_WP1982_90425 WikiPathways
EGR1 pathway0000187 AP-1 transcription factor network PID
EGR1 pathway0000343 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID
EGR1 pathway0000634 Downstream signaling in naïve CD8+ T cells PID
EGR1 pathway0000692 ErbB1 downstream signaling PID
EGR1 pathway0000916 Glucocorticoid receptor regulatory network PID
EGR1 pathway0001180 Interferon alpha/beta signaling Reactome
EGR1 pathway0001825 Regulation of Androgen receptor activity PID
EGR1 pathway0002036 Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) PID
EGR1 pathway0002037 Signaling events mediated by PRL PID
EGR1 pathway0002199 TCR NetPath
EGR1 pathway0002339 Trk receptor signaling mediated by PI3K and PLC-gamma PID
EGR1 pathway0002340 Trk receptor signaling mediated by the MAPK pathway PID
EGR1 pathway0002643 Prion diseases KEGG
EGR1 pathway0002707 Hs_Thyroid_Stimulating_Hormone_(TSH)_signaling_pathway_WP2032_89823 WikiPathways
EGR1 pathway0002750 Hs_Serotonin_Receptor_4-6-7_and_NR3C_Signaling_WP734_74438 WikiPathways
EGR1 pathway0002760 Hs_Oncostatin_M_Signaling_Pathway_WP2374_73668 WikiPathways
FOXG1 pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
FOXG1 pathway0002222 TGF_beta_Receptor NetPath
HBP1 pathway0000336 C-MYC pathway PID
HBP1 pathway0000648 E2F transcription factor network PID
HBP1 pathway0001848 Regulation of nuclear beta catenin signaling and target gene transcription PID
HBP1 pathway0002044 Signaling mediated by p38-alpha and p38-beta PID
HBP1 pathway0002393 Validated transcriptional targets of deltaNp63 isoforms PID
HBP1 pathway0002394 Validated transcriptional targets of TAp63 isoforms PID
HNF1B pathway0001835 Regulation of gene expression in early pancreatic precursor cells Reactome
HNF1B pathway0001837 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells Reactome
HNF1B pathway0002631 Maturity onset diabetes of the young KEGG
HNF1B pathway0002740 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways
IRF8 pathway0000966 GMCSF-mediated signaling events PID
IRF8 pathway0001180 Interferon alpha/beta signaling Reactome
IRF8 pathway0001181 Interferon gamma signaling Reactome
IRF8 pathway0002391 Validated targets of C-MYC transcriptional repression PID
IRF8 pathway0002815 Hs_Type_II_interferon_signaling_(IFNG)_WP619_71168 WikiPathways
MAFK pathway0000747 Factors involved in megakaryocyte development and platelet production Reactome
MEIS1 pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
NR2F6 pathway0001534 Nuclear Receptor transcription pathway Reactome
ONECUT1 pathway0000826 FOXM1 transcription factor network PID
ONECUT1 pathway0001835 Regulation of gene expression in early pancreatic precursor cells Reactome
ONECUT1 pathway0001837 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells Reactome
ONECUT1 pathway0002631 Maturity onset diabetes of the young KEGG
ONECUT1 pathway0002740 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways
ONECUT3 pathway0001835 Regulation of gene expression in early pancreatic precursor cells Reactome
ONECUT3 pathway0001837 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells Reactome
PITX2 pathway0001848 Regulation of nuclear beta catenin signaling and target gene transcription PID
PITX2 pathway0002591 TGF-beta signaling pathway KEGG
PITX2 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
PITX2 pathway0002771 Hs_BMP_Signaling_Pathway_in_Eyelid_Development_WP3927_90735 WikiPathways
PKNOX1 pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
POLR3A pathway0000532 Cytosolic sensors of pathogen-associated DNA Reactome
POLR3A pathway0001926 RNA Polymerase III Abortive And Retractive Initiation Reactome
POLR3A pathway0001927 RNA Polymerase III Chain Elongation Reactome
POLR3A pathway0001928 RNA Polymerase III Transcription Initiation From Type 1 Promoter Reactome
POLR3A pathway0001929 RNA Polymerase III Transcription Initiation From Type 2 Promoter Reactome
POLR3A pathway0001930 RNA Polymerase III Transcription Initiation From Type 3 Promoter Reactome
POLR3A pathway0001931 RNA Polymerase III Transcription Termination Reactome
POLR3A pathway0002492 Purine metabolism KEGG
POLR3A pathway0002494 Pyrimidine metabolism KEGG
POLR3A pathway0002605 Cytosolic DNA-sensing pathway KEGG
RARG pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
RARG pathway0001534 Nuclear Receptor transcription pathway Reactome
RARG pathway0001883 Retinoic acid receptors-mediated signaling PID
RARG pathway0001947 RXR and RAR heterodimerization with other nuclear receptor PID
RARG pathway0002028 Signaling by Retinoic Acid Reactome
SOX2 pathway0000549 Deactivation of the beta-catenin transactivating complex Reactome
SOX2 pathway0001701 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Reactome
SOX2 pathway0001702 POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation Reactome
SOX2 pathway0002301 Transcriptional regulation of pluripotent stem cells Reactome
SOX2 pathway0002740 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways
SOX2 pathway0002746 Hs_Dopaminergic_Neurogenesis_WP2855_87239 WikiPathways
SOX2 pathway0002821 Hs_Wnt_Signaling_Pathway_and_Pluripotency_WP399_90291 WikiPathways
SOX2 pathway0002826 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 WikiPathways
SOX2 pathway0002841 Hs_Ectoderm_Differentiation_WP2858_89329 WikiPathways
SPDEF pathway0000176 AndrogenReceptor NetPath
SPDEF pathway0001604 PDGF signaling pathway PANTHER
SPDEF pathway0001825 Regulation of Androgen receptor activity PID
SPI1 pathway0000335 C-MYB transcription factor network PID
SPI1 pathway0000702 ERK cascade ( FGF8 signaling (Mouse) ) INOH
SPI1 pathway0000703 ERK cascade ( FGF8 signaling (Xenopus) ) INOH
SPI1 pathway0000781 FGF8 signaling pathway(Mouse) ( FGF8 signaling (Mouse) ) INOH
SPI1 pathway0000782 FGF8 signaling pathway(Xenopus) ( FGF8 signaling (Xenopus) ) INOH
SPI1 pathway0000916 Glucocorticoid receptor regulatory network PID
SPI1 pathway0001127 IL4-mediated signaling events PID
SPI1 pathway0001128 IL4 NetPath
SPI1 pathway0001191 Interleukin signaling pathway PANTHER
SPI1 pathway0001799 RANKL NetPath
SPI1 pathway0001857 Regulation of retinoblastoma protein PID
SPI1 pathway0002391 Validated targets of C-MYC transcriptional repression PID
SPI1 pathway0002656 Pathways in cancer KEGG
SPI1 pathway0002668 Acute myeloid leukemia KEGG
SPI1 pathway0002874 Hs_RANKL-RANK_(Receptor_activator_of_NFKB_(ligand))_Signaling_Pathway_WP2018_90016 WikiPathways
SRY pathway0000176 AndrogenReceptor NetPath
SRY pathway0000549 Deactivation of the beta-catenin transactivating complex Reactome
SRY pathway0001825 Regulation of Androgen receptor activity PID
STAT1 pathway0000177 Angiogenesis PANTHER
STAT1 pathway0000270 BCR NetPath
STAT1 pathway0000513 CXCR4-mediated signaling events PID
STAT1 pathway0000633 Downstream signal transduction Reactome
STAT1 pathway0000652 EGF receptor signaling pathway PANTHER
STAT1 pathway0000658 EGFR1 NetPath
STAT1 pathway0000687 EPO signaling pathway PID
STAT1 pathway0000688 EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ) INOH
STAT1 pathway0000692 ErbB1 downstream signaling PID
STAT1 pathway0000780 FGF signaling pathway PID
STAT1 pathway0000899 Gene expression of SOCS by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0000900 Gene expression of SOCS1 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0000901 Gene expression of SOCS3 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0000916 Glucocorticoid receptor regulatory network PID
STAT1 pathway0000966 GMCSF-mediated signaling events PID
STAT1 pathway0000976 Growth hormone receptor signaling Reactome
STAT1 pathway0001079 IFN-gamma pathway PID
STAT1 pathway0001080 IFN alpha signaling pathway((JAK1 TYK2 STAT1 STAT2) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) ) INOH
STAT1 pathway0001081 IFN alpha signaling pathway(JAK1 TYK2 STAT1 STAT3) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) ) INOH
STAT1 pathway0001082 IFN alpha signaling pathway(JAK1 TYK2 STAT1) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) ) INOH
STAT1 pathway0001084 IFN gamma signaling pathway(JAK1 JAK2 STAT1) ( IFN gamma signaling(JAK1 JAK2 STAT1) ) INOH
STAT1 pathway0001109 IL-5 signaling pathway(JAK1 JAK2 STAT1 STAT5) ( IL-5 signaling(JAK1 JAK2 STAT1 STAT5) ) INOH
STAT1 pathway0001112 IL-7 NetPath
STAT1 pathway0001116 IL12-mediated signaling events PID
STAT1 pathway0001119 IL2-mediated signaling events PID
STAT1 pathway0001120 IL2 NetPath
STAT1 pathway0001123 IL23-mediated signaling events PID
STAT1 pathway0001124 IL27-mediated signaling events PID
STAT1 pathway0001128 IL4 NetPath
STAT1 pathway0001130 IL5 NetPath
STAT1 pathway0001131 IL6-mediated signaling events PID
STAT1 pathway0001132 IL6 NetPath
STAT1 pathway0001135 IL9 NetPath
STAT1 pathway0001179 Interferon-gamma signaling pathway PANTHER
STAT1 pathway0001180 Interferon alpha/beta signaling Reactome
STAT1 pathway0001181 Interferon gamma signaling Reactome
STAT1 pathway0001188 Interleukin-6 signaling Reactome
STAT1 pathway0001191 Interleukin signaling pathway PANTHER
STAT1 pathway0001219 ISG15 antiviral mechanism Reactome
STAT1 pathway0001226 JAK-STAT pathway and regulation pathway ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0001228 JAK/STAT signaling pathway PANTHER
STAT1 pathway0001246 KitReceptor NetPath
STAT1 pathway0001264 Leptin NetPath
STAT1 pathway0001560 Oxidative stress response PANTHER
STAT1 pathway0001604 PDGF signaling pathway PANTHER
STAT1 pathway0001606 PDGFR-beta signaling pathway PID
STAT1 pathway0001697 Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0001727 Prolactin NetPath
STAT1 pathway0001799 RANKL NetPath
STAT1 pathway0001805 Ras Pathway PANTHER
STAT1 pathway0001840 Regulation of IFNA signaling Reactome
STAT1 pathway0001841 Regulation of IFNG signaling Reactome
STAT1 pathway0002000 SHP2 signaling PID
STAT1 pathway0002010 Signaling by cytosolic FGFR1 fusion mutants Reactome
STAT1 pathway0002030 Signaling by SCF-KIT Reactome
STAT1 pathway0002039 Signaling events mediated by Stem cell factor receptor (c-Kit) PID
STAT1 pathway0002040 Signaling events mediated by TCPTP PID
STAT1 pathway0002199 TCR NetPath
STAT1 pathway0002246 TNF receptor signaling pathway PID
STAT1 pathway0002249 TNFalpha NetPath
STAT1 pathway0002354 TSH NetPath
STAT1 pathway0002355 TSLP NetPath
STAT1 pathway0002568 Chemokine signaling pathway KEGG
STAT1 pathway0002602 Toll-like receptor signaling pathway KEGG
STAT1 pathway0002606 Jak-STAT signaling pathway KEGG
STAT1 pathway0002649 Leishmaniasis KEGG
STAT1 pathway0002652 Toxoplasmosis KEGG
STAT1 pathway0002655 Hepatitis C KEGG
STAT1 pathway0002656 Pathways in cancer KEGG
STAT1 pathway0002659 Pancreatic cancer KEGG
STAT1 pathway0002682 Hs_Interferon_type_I_signaling_pathways_WP585_85198 WikiPathways
STAT1 pathway0002689 Hs_Cytokines_and_Inflammatory_Response_WP530_79331 WikiPathways
STAT1 pathway0002712 Hs_Leptin_signaling_pathway_WP2034_89856 WikiPathways
STAT1 pathway0002718 Hs_Interleukin-11_Signaling_Pathway_WP2332_79525 WikiPathways
STAT1 pathway0002725 Hs_Endochondral_Ossification_WP474_87977 WikiPathways
STAT1 pathway0002731 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 WikiPathways
STAT1 pathway0002735 Hs_PDGF_Pathway_WP2526_82681 WikiPathways
STAT1 pathway0002740 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways
STAT1 pathway0002743 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways
STAT1 pathway0002751 Hs_Integrated_Cancer_Pathway_WP1971_82939 WikiPathways
STAT1 pathway0002760 Hs_Oncostatin_M_Signaling_Pathway_WP2374_73668 WikiPathways
STAT1 pathway0002813 Hs_One_carbon_metabolism_and_related_pathways_WP3940_91096 WikiPathways
STAT1 pathway0002829 Hs_Kit_receptor_signaling_pathway_WP304_78799 WikiPathways
STAT1 pathway0002837 Hs_IL-5_Signaling_Pathway_WP127_78498 WikiPathways
STAT1 pathway0002844 Hs_IL-2_Signaling_Pathway_WP49_91243 WikiPathways
STAT1 pathway0002858 Hs_IL-6_signaling_pathway_WP364_89832 WikiPathways
STAT1 pathway0002860 Hs_Prolactin_Signaling_Pathway_WP2037_90015 WikiPathways
STAT1 pathway0002864 Hs_IL-4_Signaling_Pathway_WP395_89828 WikiPathways
STAT1 pathway0002865 Hs_Brain-Derived_Neurotrophic_Factor_(BDNF)_signaling_pathway_WP2380_89803 WikiPathways
STAT1 pathway0002866 Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 WikiPathways
STAT1 pathway0002879 Hs_IL-9_Signaling_Pathway_WP22_79264 WikiPathways
STAT1 pathway0002880 Hs_Insulin_signalling_in_adipocytes_(diabetic_condition)_WP3635_86059 WikiPathways
STAT1 pathway0002881 Hs_Insulin_signalling_in_adipocytes_(normal_condition)_WP3634_86060 WikiPathways
TBP pathway0000264 B-WICH complex positively regulates rRNA expression Reactome
TBP pathway0000902 General transcription by RNA polymerase I PANTHER
TBP pathway0000916 Glucocorticoid receptor regulatory network PID
TBP pathway0001035 HIV Transcription Initiation Reactome
TBP pathway0001046 Huntington disease PANTHER
TBP pathway0001512 NoRC negatively regulates rRNA expression Reactome
TBP pathway0001857 Regulation of retinoblastoma protein PID
TBP pathway0001866 Regulation of TP53 Activity through Phosphorylation Reactome
TBP pathway0001913 RNA Polymerase I Chain Elongation Reactome
TBP pathway0001914 RNA Polymerase I Promoter Escape Reactome
TBP pathway0001916 RNA Polymerase I Transcription Initiation Reactome
TBP pathway0001917 RNA Polymerase I Transcription Termination Reactome
TBP pathway0001918 RNA Polymerase II HIV Promoter Escape Reactome
TBP pathway0001919 RNA Polymerase II Pre-transcription Events Reactome
TBP pathway0001920 RNA Polymerase II Promoter Escape Reactome
TBP pathway0001921 RNA polymerase II transcribes snRNA genes Reactome
TBP pathway0001923 RNA Polymerase II Transcription Initiation And Promoter Clearance Reactome
TBP pathway0001924 RNA Polymerase II Transcription Initiation Reactome
TBP pathway0001925 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening Reactome
TBP pathway0001926 RNA Polymerase III Abortive And Retractive Initiation Reactome
TBP pathway0001928 RNA Polymerase III Transcription Initiation From Type 1 Promoter Reactome
TBP pathway0001929 RNA Polymerase III Transcription Initiation From Type 2 Promoter Reactome
TBP pathway0001930 RNA Polymerase III Transcription Initiation From Type 3 Promoter Reactome
TBP pathway0002062 SIRT1 negatively regulates rRNA Expression Reactome
TBP pathway0002296 Transcription of the HIV genome Reactome
TBP pathway0002297 Transcription regulation by bZIP transcription factor PANTHER
TBP pathway0002391 Validated targets of C-MYC transcriptional repression PID
TBP pathway0002642 Huntington's disease KEGG
TBX2 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
TBX20 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
TCF7L2 pathway0000154 Alzheimer disease-presenilin pathway PANTHER
TCF7L2 pathway0000177 Angiogenesis PANTHER
TCF7L2 pathway0000187 AP-1 transcription factor network PID
TCF7L2 pathway0000309 Binding of TCF/LEF:CTNNB1 to target gene promoters Reactome
TCF7L2 pathway0000340 Ca2+ pathway Reactome
TCF7L2 pathway0000341 Cadherin signaling pathway PANTHER
TCF7L2 pathway0000355 Canonical Wnt signaling pathway ( C. elegans endoderm induction Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0000356 Canonical Wnt signaling pathway ( Canonical Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0000357 Canonical Wnt signaling pathway ( Drosophila Wingless/Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0000358 Canonical Wnt signaling pathway ( Mammalian Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0000359 Canonical Wnt signaling pathway ( Xenopus axis formation Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0000549 Deactivation of the beta-catenin transactivating complex Reactome
TCF7L2 pathway0000816 Formation of the beta-catenin:TCF transactivating complex Reactome
TCF7L2 pathway0001078 ID NetPath
TCF7L2 pathway0001315 Mammalian Wnt signaling pathway ( Mammalian Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0001848 Regulation of nuclear beta catenin signaling and target gene transcription PID
TCF7L2 pathway0001876 Repression of WNT target genes Reactome
TCF7L2 pathway0002046 Signaling with Wnt (Canonical) ( C. elegans endoderm induction Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002047 Signaling with Wnt (Canonical) ( Canonical Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002048 Signaling with Wnt (Canonical) ( Drosophila Wingless/Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002049 Signaling with Wnt (Canonical) ( Mammalian Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002050 Signaling with Wnt (Canonical) ( Xenopus axis formation Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002051 Signaling with Wnt (Mammal) ( Mammalian Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002052 Signaling with Wnt (Xenopus) ( Xenopus axis formation Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002053 Signaling without Wnt (Canonical) ( C. elegans endoderm induction Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002054 Signaling without Wnt (Canonical) ( Canonical Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002055 Signaling without Wnt (Canonical) ( Drosophila Wingless/Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002056 Signaling without Wnt (Canonical) ( Mammalian Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002057 Signaling without Wnt (Canonical) ( Xenopus axis formation Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002058 Signaling without Wnt (Mammal) ( Mammalian Wnt signaling pathway Diagram ) INOH
TCF7L2 pathway0002181 Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Reactome
TCF7L2 pathway0002439 Wnt NetPath
TCF7L2 pathway0002449 Wnt signaling pathway PANTHER
TCF7L2 pathway0002587 Wnt signaling pathway KEGG
TCF7L2 pathway0002597 Adherens junction KEGG
TCF7L2 pathway0002627 Melanogenesis KEGG
TCF7L2 pathway0002656 Pathways in cancer KEGG
TCF7L2 pathway0002657 Colorectal cancer KEGG
TCF7L2 pathway0002660 Endometrial cancer KEGG
TCF7L2 pathway0002662 Prostate cancer KEGG
TCF7L2 pathway0002668 Acute myeloid leukemia KEGG
TCF7L2 pathway0002677 Arrhythmogenic right ventricular cardiomyopathy (ARVC) KEGG
TP63 pathway0000075 Activation of PUMA and translocation to mitochondria Reactome
TP63 pathway0000608 Direct p53 effectors PID
TP63 pathway0001046 Huntington disease PANTHER
TP63 pathway0001577 p53 pathway by glucose deprivation PANTHER
TP63 pathway0001578 p53 pathway PANTHER
TP63 pathway0001580 P53 pathway feedback loops 1 PANTHER
TP63 pathway0001581 p53 pathway feedback loops 2 PANTHER
TP63 pathway0001582 p73 transcription factor network PID
TP63 pathway0001864 Regulation of TP53 Activity through Association with Co-factors Reactome
TP63 pathway0002269 TP53 Regulates Metabolic Genes Reactome
TP63 pathway0002271 TP53 Regulates Transcription of Caspase Activators and Caspases Reactome
TP63 pathway0002272 TP53 Regulates Transcription of Death Receptors and Ligands Reactome
TP63 pathway0002274 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Reactome
TP63 pathway0002277 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain Reactome
TP63 pathway0002393 Validated transcriptional targets of deltaNp63 isoforms PID
TP63 pathway0002394 Validated transcriptional targets of TAp63 isoforms PID
TP63 pathway0002702 Hs_Focal_Adhesion_WP306_80308 WikiPathways
TP63 pathway0002758 Hs_TGF-beta_Receptor_Signaling_WP560_90187 WikiPathways
TP63 pathway0002843 Hs_Urea_cycle_and_metabolism_of_amino_groups_WP497_72142 WikiPathways
TP63 pathway0002849 Hs_Hypothetical_Craniofacial_Development_Pathway_WP3655_88473 WikiPathways
ZNF263 pathway0000905 Generic Transcription Pathway Reactome