General Details

Super-enhancer:SE_02_33600374
Genomic Locus: chr18: 9866876-9881703
Size/Length:14827bp
Conservation:0.0182524
BioSample Type:Cell line
Tissue Type:Haematopoietic and lymphoid tissue
Sample Name:SET2
Source:NCBI GEO/SRA
Element:1
Rank:374
ChIP Density(Case):18539.6808
ChIP Density(Input):2317.4601

Super-enhancer Associated Network


* The complex regulatory networks formed by this SE , SE associated genes , TFs binding to the SE and their upstream pathways can be interactively visualized.


Fimo:
SE-Gene Linking Strategies:
Pathway Enriciment Threshold:
Top Pathway:
 



Super-enhancer Associated Statistics

Associated Gene Details

ROSE Overlap:.
ROSE Proximal:TXNDC2,VAPA
ROSE Closest:TXNDC2
The Closest Active:TXNDC2

Factors Binding to Super-enhancer




Using these SE element regions to analyze by online tools GREAT *The TFs binding to this SE identified by ChIP-seq.

Chrome Element_Start Element_End TF TF Source TF_Start TF_End TF Class Master TF
chr18 9866876 9881703 CDK8 Remap_0281 9868672 9868924 TcoF-DB_TcoF N
chr18 9866876 9881703 CDK8 Remap_0281 9869333 9870776 TcoF-DB_TcoF N
chr18 9866876 9881703 CDK8 Remap_0281 9876235 9877935 TcoF-DB_TcoF N
chr18 9866876 9881703 STAT1 ChIP-Atlas_1201 9877317 9877640 Immunoglobulin fold N
chr18 9866876 9881703 STAT1 ChIP-Atlas_1205 9868575 9869026 Immunoglobulin fold N
chr18 9866876 9881703 STAT1 ChIP-Atlas_1205 9869648 9870570 Immunoglobulin fold N
chr18 9866876 9881703 STAT1 ChIP-Atlas_1205 9876591 9877921 Immunoglobulin fold N
chr18 9866876 9881703 STAT1 ChIP-Atlas_1206 9868615 9868939 Immunoglobulin fold N
chr18 9866876 9881703 STAT1 ChIP-Atlas_1206 9869646 9870260 Immunoglobulin fold N
chr18 9866876 9881703 STAT1 ChIP-Atlas_1206 9876775 9877812 Immunoglobulin fold N

Using these SE element regions to analyze by online tools GREAT * The TFs binding to this SE predicted by Motif.

Chrome Element_Start Element_End TF Database TF_Start TF_End Score P_Value TF Class Master TF
chr18 9866876 9881703 BCL6 Transfac.V$BCL6_02 9870851 9870864 17.70370 9.39e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 BCL6B Transfac.V$BCL6B_04 9867832 9867847 15.21080 5.55e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 BCL6B Uniprobe.UP00043_2 9867832 9867847 15.13860 5.55e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 CDX2 Transfac.V$CDX2_Q5_01 9873284 9873294 12.50980 2.45e-07 Helix-turn-helix domains N
chr18 9866876 9881703 EGR2 JASPAR2014.MA0472.1 9868424 9868438 18.18030 3.33e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 ELF3 Uniprobe.UP00407_1 9871650 9871662 14.63110 9.71e-07 Helix-turn-helix domains N
chr18 9866876 9881703 ESRRB Transfac.V$ERR2_01 9870045 9870056 17.64620 5.05e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 ESRRB JASPAR2014.MA0141.2 9876401 9876412 16.85390 6.85e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 FOXC1 Transfac.V$FOXC1_02 9879584 9879596 17.33930 4.85e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXC1 Jolma2013.FOXC1_DBD 9879584 9879596 17.32350 4.85e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXD3 JASPAR2014.MA0041.1 9873823 9873834 15.76090 7.86e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXD3 JASPAR2014.MA0041.1 9881534 9881545 15.76090 7.86e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXD3 JASPAR2014.MA0041.1 9881538 9881549 15.76090 7.86e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXI1 Transfac.V$HFH3_01 9876133 9876145 15.57140 8.07e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXI1 JASPAR2014.MA0042.1 9875823 9875834 15.47830 3.9e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXJ2 Transfac.V$FOXJ2_01 9873819 9873836 15.84780 4e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXJ2 Transfac.V$FOXJ2_01 9875819 9875836 16.23910 1.45e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXJ2 Transfac.V$FOXJ2_01 9881530 9881547 15.89130 3.59e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXJ2 Transfac.V$FOXJ2_02 9878124 9878137 16.45310 8.41e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXJ2 Transfac.V$FOXJ2_03 9873255 9873268 21.03330 4.67e-08 Helix-turn-helix domains N
chr18 9866876 9881703 FOXJ2 Jolma2013.FOXJ2_DBD 9873255 9873268 20.97270 4.67e-08 Helix-turn-helix domains N
chr18 9866876 9881703 FOXJ3 Transfac.V$FOXJ3_08 9873255 9873268 21.20000 4.67e-08 Helix-turn-helix domains N
chr18 9866876 9881703 FOXJ3 Transfac.V$FOXJ3_11 9873255 9873268 19.51610 7.89e-08 Helix-turn-helix domains N
chr18 9866876 9881703 FOXJ3 Jolma2013.FOXJ3_DBD_2 9873255 9873268 21.15310 4.67e-08 Helix-turn-helix domains N
chr18 9866876 9881703 FOXJ3 Jolma2013.Foxj3_DBD_2 9873255 9873268 19.45160 7.89e-08 Helix-turn-helix domains N
chr18 9866876 9881703 FOXP1 Transfac.V$FOXP1_01 9873813 9873832 7.44048 7.08e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXP1 Transfac.V$FOXP1_01 9873823 9873842 11.23810 3e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXP1 JASPAR2014.MA0481.1 9874172 9874186 16.45070 8.29e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXQ1 Transfac.V$HFH1_01 9873253 9873264 17.26800 2.36e-07 Helix-turn-helix domains N
chr18 9866876 9881703 FOXQ1 JASPAR2014.MA0040.1 9873254 9873264 15.79380 8.22e-07 Helix-turn-helix domains N
chr18 9866876 9881703 GC Transfac.V$GC_01 9867390 9867403 17.82860 1.74e-07 UNKNOW N
chr18 9866876 9881703 HIC1 Transfac.V$HIC1_07 9874492 9874509 15.77590 6.38e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 HIC1 Jolma2013.Hic1_DBD 9874492 9874509 15.88660 6.76e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 HIVEP2 Transfac.V$MIBP1_Q6 9880433 9880444 15.83470 9.49e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 HNF1A Transfac.V$HNF1_Q6 9879758 9879775 15.45650 7.63e-07 Helix-turn-helix domains N
chr18 9866876 9881703 IKZF1 Transfac.V$IK_Q5 9873067 9873076 15.12370 8.07e-07 Zinc-coordinating DNA-binding domains Y
chr18 9866876 9881703 IRF3 Transfac.V$IRF3_Q3 9878313 9878325 16.20370 9.63e-08 Helix-turn-helix domains N
chr18 9866876 9881703 JUNB JASPAR2014.MA0490.1 9874798 9874808 16.20410 8.73e-07 Basic domains N
chr18 9866876 9881703 KLF13 Transfac.V$BTEB3_Q5 9876242 9876254 16.53700 1.7e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 KLF5 JASPAR2014.MA0599.1 9867392 9867401 17.46940 4.4e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 KLF7 Transfac.V$KLF7_03 9867389 9867404 17.23460 9.81e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 KLF7 Uniprobe.UP00093_1 9867389 9867404 17.14810 9.95e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 MAF Transfac.V$MAF_Q6_01 9868490 9868500 14.93330 6.7e-07 Basic domains N
chr18 9866876 9881703 MTERF Transfac.V$MTERF_01 9878784 9878797 19.95510 1.23e-07 UNKNOW N
chr18 9866876 9881703 MYC Transfac.V$CMYC_02 9875344 9875355 18.96910 4.4e-07 Basic domains N
chr18 9866876 9881703 NR0B1 Transfac.V$DAX1_01 9870042 9870061 16.00000 8.2e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 NR2E3 Transfac.V$PNR_01 9869592 9869605 18.62240 4.06e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 NR2F1 Transfac.V$NR2F1_03 9874517 9874532 16.49480 9.07e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 NR2F1 Transfac.V$NR2F1_03 9880048 9880063 16.49480 9.07e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 NR2F1 Transfac.V$NR2F1_03 9881326 9881341 16.49480 9.07e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 NR2F1 Jolma2013.NR2F1_DBD_2 9874517 9874532 16.51850 9.26e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 NR2F1 Jolma2013.NR2F1_DBD_2 9880048 9880063 16.51850 9.26e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 NR2F1 Jolma2013.NR2F1_DBD_2 9881326 9881341 16.51850 9.26e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 NR2F6 Jolma2013.Nr2f6_DBD 9874517 9874531 16.57730 3e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 NR2F6 Jolma2013.Nr2f6_DBD 9880049 9880063 16.57730 3e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 NR2F6 Jolma2013.Nr2f6_DBD 9881326 9881340 16.57730 3e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 NR5A2 JASPAR2014.MA0505.1 9876400 9876414 17.20690 9.07e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 PAX4 Transfac.V$PAX4_03 9867390 9867401 13.56570 3.48e-07 Helix-turn-helix domains N
chr18 9866876 9881703 PAX5 Transfac.V$PAX5_Q6 9877810 9877819 11.87640 3.43e-07 Helix-turn-helix domains N
chr18 9866876 9881703 PITX2 Transfac.V$PITX2_Q2 9868334 9868344 16.03700 2.45e-07 Helix-turn-helix domains N
chr18 9866876 9881703 PITX2 Transfac.V$PITX2_Q2 9873537 9873547 16.03700 2.45e-07 Helix-turn-helix domains N
chr18 9866876 9881703 PITX2 Transfac.V$PITX2_Q2 9873671 9873681 16.03700 2.45e-07 Helix-turn-helix domains N
chr18 9866876 9881703 PITX2 Transfac.V$PITX2_Q2 9874474 9874484 16.03700 2.45e-07 Helix-turn-helix domains N
chr18 9866876 9881703 PITX2 Transfac.V$PITX2_Q2 9874608 9874618 16.03700 2.45e-07 Helix-turn-helix domains N
chr18 9866876 9881703 PITX2 Transfac.V$PITX2_Q2 9875864 9875874 16.03700 2.45e-07 Helix-turn-helix domains N
chr18 9866876 9881703 PITX2 Transfac.V$PITX2_Q2 9875998 9876008 16.03700 2.45e-07 Helix-turn-helix domains N
chr18 9866876 9881703 PITX2 Transfac.V$PITX2_Q2 9880088 9880098 16.03700 2.45e-07 Helix-turn-helix domains N
chr18 9866876 9881703 PITX2 Transfac.V$PITX2_Q2 9881283 9881293 16.03700 2.45e-07 Helix-turn-helix domains N
chr18 9866876 9881703 PITX2 Transfac.V$PITX2_Q2 9881418 9881428 16.03700 2.45e-07 Helix-turn-helix domains N
chr18 9866876 9881703 POLR3A Transfac.V$RPC155_01 9873582 9873597 21.24770 2.73e-08 ENCODE_TF N
chr18 9866876 9881703 POLR3A Transfac.V$RPC155_01 9874521 9874536 23.59630 1.88e-09 ENCODE_TF N
chr18 9866876 9881703 POLR3A Transfac.V$RPC155_01 9875909 9875924 21.07340 3.25e-08 ENCODE_TF N
chr18 9866876 9881703 POLR3A Transfac.V$RPC155_01 9880044 9880059 23.59630 1.88e-09 ENCODE_TF N
chr18 9866876 9881703 POLR3A Transfac.V$RPC155_01 9881330 9881345 23.59630 1.88e-09 ENCODE_TF N
chr18 9866876 9881703 POU2F2 Transfac.V$POU2F2_02 9873890 9873900 14.95500 6.07e-07 Helix-turn-helix domains N
chr18 9866876 9881703 POU2F2 Jolma2013.POU2F2_DBD 9873890 9873900 14.90400 6.07e-07 Helix-turn-helix domains N
chr18 9866876 9881703 POU3F3 Transfac.V$POU3F3_02 9873889 9873901 16.26260 8.28e-07 Helix-turn-helix domains N
chr18 9866876 9881703 POU3F3 Jolma2013.POU3F3_DBD 9873889 9873901 16.23640 8.28e-07 Helix-turn-helix domains N
chr18 9866876 9881703 RARA Jolma2013.Rara_DBD_3 9874517 9874531 13.81440 9.48e-07 Zinc-coordinating DNA-binding domains Y
chr18 9866876 9881703 RARA Jolma2013.Rara_DBD_3 9880049 9880063 13.81440 9.48e-07 Zinc-coordinating DNA-binding domains Y
chr18 9866876 9881703 RARA Jolma2013.Rara_DBD_3 9881326 9881340 13.81440 9.48e-07 Zinc-coordinating DNA-binding domains Y
chr18 9866876 9881703 RARG Jolma2013.RARG_DBD 9874517 9874533 15.05150 7.65e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 RARG Jolma2013.RARG_DBD 9880047 9880063 15.05150 7.65e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 RARG Jolma2013.RARG_DBD 9881326 9881342 15.05150 7.65e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 RARG Jolma2013.Rarg_DBD 9874517 9874532 16.51550 3.83e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 RARG Jolma2013.Rarg_DBD 9880048 9880063 16.51550 3.83e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 RARG Jolma2013.Rarg_DBD 9881326 9881341 16.51550 3.83e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 RREB1 Transfac.V$RREB1_01 9872960 9872973 18.08330 6.05e-07 Zinc-coordinating DNA-binding domains Y
chr18 9866876 9881703 RUNX1 Transfac.V$EVI1_04 9877135 9877149 16.43360 7e-07 Immunoglobulin fold Y
chr18 9866876 9881703 RUNX2 JASPAR2014.MA0511.1 9870651 9870665 16.85250 5.94e-07 Immunoglobulin fold N
chr18 9866876 9881703 SOX11 Transfac.V$SOX11_04 9869358 9869371 13.87950 5.25e-07 Other all-alpha-helical DNA-binding domains N
chr18 9866876 9881703 SOX11 Uniprobe.UP00030_2 9869358 9869371 13.80160 5.91e-07 Other all-alpha-helical DNA-binding domains N
chr18 9866876 9881703 SOX18 Transfac.V$SOX18_04 9870517 9870532 13.87150 9.38e-09 Other all-alpha-helical DNA-binding domains N
chr18 9866876 9881703 SOX18 Uniprobe.UP00064_2 9870517 9870532 13.78890 1.04e-08 Other all-alpha-helical DNA-binding domains N
chr18 9866876 9881703 SOX2 Transfac.V$SOX2_05 9869284 9869298 16.19670 9.99e-07 Other all-alpha-helical DNA-binding domains N
chr18 9866876 9881703 SOX9 Transfac.V$SOX9_05 9873955 9873970 10.83080 2.55e-07 Other all-alpha-helical DNA-binding domains N
chr18 9866876 9881703 SOX9 Transfac.V$SOX9_05 9874187 9874202 10.83080 2.55e-07 Other all-alpha-helical DNA-binding domains N
chr18 9866876 9881703 SP1 Transfac.V$SP1_02 9867832 9867842 18.90740 2.8e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 SP2 JASPAR2014.MA0516.1 9868148 9868162 17.08620 9.62e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 SRY Transfac.V$SRY_05 9868620 9868636 13.69880 5.91e-07 Other all-alpha-helical DNA-binding domains N
chr18 9866876 9881703 SRY Uniprobe.UP00016_2 9868620 9868636 13.67470 6.04e-07 Other all-alpha-helical DNA-binding domains N
chr18 9866876 9881703 TBX5 Transfac.V$TBX5_Q2 9875078 9875092 18.36080 3.83e-07 Immunoglobulin fold N
chr18 9866876 9881703 TCF3 Transfac.V$E2A_Q2 9875886 9875899 18.16490 2.8e-08 Basic domains N
chr18 9866876 9881703 TCF3 Transfac.V$TCF3_05 9875779 9875793 9.89958 1.99e-07 Basic domains N
chr18 9866876 9881703 TCF3 Uniprobe.UP00058_2 9875779 9875793 9.88333 1.77e-07 Basic domains N
chr18 9866876 9881703 TFAP2C Transfac.V$TFAP2C_03 9869267 9869277 15.32790 9.28e-07 Basic domains N
chr18 9866876 9881703 TFAP2C Jolma2013.TFAP2C_full_3 9869267 9869277 15.28870 9.28e-07 Basic domains N
chr18 9866876 9881703 TFAP4 Transfac.V$AP4_01 9867191 9867208 17.12400 9.99e-07 Basic domains N
chr18 9866876 9881703 TP53 Transfac.V$P53_02 9874836 9874845 13.71600 8.51e-07 Immunoglobulin fold N
chr18 9866876 9881703 ZBTB7B Transfac.V$ZBTB7B_03 9879371 9879385 17.60490 8.47e-08 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 ZBTB7B Uniprobe.UP00047_1 9879371 9879385 17.50930 8.05e-08 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 ZNF143 Transfac.V$STAF_02 9866976 9866996 18.45370 3.75e-07 Zinc-coordinating DNA-binding domains N
chr18 9866876 9881703 ZNF263 JASPAR2014.MA0528.1 9867823 9867843 16.75510 9.59e-07 Zinc-coordinating DNA-binding domains N

The Upstream Pathways of TFs Binding to SE



TF Pathway ID Pathway Name Source
BCL6 pathway0000270 BCR NetPath
BCL6 pathway0000271 BCR signaling pathway PID
BCL6 pathway0000608 Direct p53 effectors PID
BCL6 pathway0000827 FoxO family signaling PID
BCL6 pathway0001127 IL4-mediated signaling events PID
BCL6 pathway0002034 Signaling events mediated by HDAC Class II PID
BCL6 pathway0002277 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain Reactome
BCL6 pathway0002874 Hs_RANKL-RANK_(Receptor_activator_of_NFKB_(ligand))_Signaling_Pathway_WP2018_90016 WikiPathways
CDK8 pathway0000119 AKT(PKB)-Bad signaling ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ) INOH
CDK8 pathway0000120 AKT(PKB)-Bad signaling ( IL-7 signaling(JAK1 JAK3 STAT5) ) INOH
CDK8 pathway0000483 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Reactome
CDK8 pathway0000484 Constitutive Signaling by NOTCH1 PEST Domain Mutants Reactome
CDK8 pathway0000639 Drosophila Toll-like receptor signaling ( Drosophila Toll-like receptor signaling ) INOH
CDK8 pathway0000905 Generic Transcription Pathway Reactome
CDK8 pathway0000994 Hedgehog NetPath
CDK8 pathway0001524 NOTCH1 Intracellular Domain Regulates Transcription Reactome
CDK8 pathway0001697 Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram ) INOH
CDK8 pathway0001704 PPARA activates gene expression Reactome
CDK8 pathway0002069 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome
CDK8 pathway0002302 Transcriptional regulation of white adipocyte differentiation Reactome
CDK8 pathway0002407 VEGF signaling pathway ( VEGF signaling pathway ) INOH
CDK8 pathway0002806 Hs_Sterol_Regulatory_Element-Binding_Proteins_(SREBP)_signalling_WP1982_90425 WikiPathways
CDX2 pathway0001702 POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation Reactome
CDX2 pathway0002181 Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Reactome
EGR2 pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
EGR2 pathway0000343 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID
EGR2 pathway0001127 IL4-mediated signaling events PID
EGR2 pathway0002302 Transcriptional regulation of white adipocyte differentiation Reactome
EGR2 pathway0002394 Validated transcriptional targets of TAp63 isoforms PID
EGR2 pathway0002820 Hs_Fatty_Acid_Beta_Oxidation_WP143_79783 WikiPathways
ELF3 pathway0000658 EGFR1 NetPath
ELF3 pathway0001604 PDGF signaling pathway PANTHER
ESRRB pathway0001534 Nuclear Receptor transcription pathway Reactome
ESRRB pathway0002821 Hs_Wnt_Signaling_Pathway_and_Pluripotency_WP399_90291 WikiPathways
FOXC1 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
FOXC1 pathway0002826 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 WikiPathways
FOXD3 pathway0001701 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Reactome
FOXD3 pathway0002747 Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways
GC pathway0002430 Vitamin D (calciferol) metabolism Reactome
GC pathway0002431 Vitamin D metabolism and pathway PANTHER
HIC1 pathway0000608 Direct p53 effectors PID
HIC1 pathway0000648 E2F transcription factor network PID
HNF1A pathway0000825 FOXA2 and FOXA3 transcription factor networks PID
HNF1A pathway0001132 IL6 NetPath
HNF1A pathway0001714 Presenilin action in Notch and Wnt signaling PID
HNF1A pathway0001834 Regulation of gene expression in beta cells Reactome
HNF1A pathway0002631 Maturity onset diabetes of the young KEGG
IKZF1 pathway0000343 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID
IRF3 pathway0000070 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon Reactome
IRF3 pathway0000747 Factors involved in megakaryocyte development and platelet production Reactome
IRF3 pathway0001180 Interferon alpha/beta signaling Reactome
IRF3 pathway0001181 Interferon gamma signaling Reactome
IRF3 pathway0001212 IRF3-mediated induction of type I IFN Reactome
IRF3 pathway0001213 IRF3 mediated activation of type 1 IFN Reactome
IRF3 pathway0001219 ISG15 antiviral mechanism Reactome
IRF3 pathway0001297 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Reactome
IRF3 pathway0001469 Negative regulators of RIG-I/MDA5 signaling Reactome
IRF3 pathway0001843 Regulation of innate immune responses to cytosolic DNA Reactome
IRF3 pathway0002264 Toll receptor signaling pathway PANTHER
IRF3 pathway0002278 TRAF3-dependent IRF activation pathway Reactome
IRF3 pathway0002282 TRAF6 mediated IRF7 activation Reactome
IRF3 pathway0002602 Toll-like receptor signaling pathway KEGG
IRF3 pathway0002604 RIG-I-like receptor signaling pathway KEGG
IRF3 pathway0002605 Cytosolic DNA-sensing pathway KEGG
IRF3 pathway0002655 Hepatitis C KEGG
IRF3 pathway0002782 Hs_p38_MAPK_Signaling_Pathway_WP400_72084 WikiPathways
IRF3 pathway0002789 Hs_Complement_and_Coagulation_Cascades_WP558_90196 WikiPathways
IRF3 pathway0002824 Hs_RIG-I-like_Receptor_Signaling_WP3865_88186 WikiPathways
IRF3 pathway0002845 Hs_TLR4_Signaling_and_Tolerance_WP3851_90114 WikiPathways
JUNB pathway0000187 AP-1 transcription factor network PID
JUNB pathway0000229 ATF-2 transcription factor network PID
JUNB pathway0000270 BCR NetPath
JUNB pathway0000343 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID
JUNB pathway0000347 Calcium signaling in the CD4+ TCR pathway PID
JUNB pathway0000634 Downstream signaling in naïve CD8+ T cells PID
JUNB pathway0001131 IL6-mediated signaling events PID
JUNB pathway0001147 Inflammation mediated by chemokine and cytokine signaling pathway PANTHER
JUNB pathway0002069 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome
JUNB pathway0002217 TGF-beta signaling pathway PANTHER
JUNB pathway0002222 TGF_beta_Receptor NetPath
JUNB pathway0002249 TNFalpha NetPath
JUNB pathway0002392 Validated transcriptional targets of AP1 family members Fra1 and Fra2 PID
JUNB pathway0002829 Hs_Kit_receptor_signaling_pathway_WP304_78799 WikiPathways
JUNB pathway0002853 Hs_TGF-beta_Signaling_Pathway_WP366_90028 WikiPathways
KLF5 pathway0002302 Transcriptional regulation of white adipocyte differentiation Reactome
KLF5 pathway0002758 Hs_TGF-beta_Receptor_Signaling_WP560_90187 WikiPathways
KLF7 pathway0002689 Hs_Cytokines_and_Inflammatory_Response_WP530_79331 WikiPathways
MAF pathway0000187 AP-1 transcription factor network PID
MAF pathway0000335 C-MYB transcription factor network PID
MAF pathway0000343 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID
MAF pathway0002688 Hs_TYROBP_Causal_Network_WP3945_90843 WikiPathways
MYC pathway0000187 AP-1 transcription factor network PID
MYC pathway0000309 Binding of TCF/LEF:CTNNB1 to target gene promoters Reactome
MYC pathway0000335 C-MYB transcription factor network PID
MYC pathway0000336 C-MYC pathway PID
MYC pathway0000388 CD40/CD40L signaling PID
MYC pathway0000403 Ceramide signaling pathway PID
MYC pathway0000483 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Reactome
MYC pathway0000484 Constitutive Signaling by NOTCH1 PEST Domain Mutants Reactome
MYC pathway0000515 Cyclin A:Cdk2-associated events at S phase entry Reactome
MYC pathway0000518 Cyclin E associated events during G1/S transition Reactome
MYC pathway0000648 E2F transcription factor network PID
MYC pathway0000658 EGFR1 NetPath
MYC pathway0000816 Formation of the beta-catenin:TCF transactivating complex Reactome
MYC pathway0000826 FOXM1 transcription factor network PID
MYC pathway0001119 IL2-mediated signaling events PID
MYC pathway0001121 IL2 signaling events mediated by PI3K PID
MYC pathway0001122 IL2 signaling events mediated by STAT5 PID
MYC pathway0001131 IL6-mediated signaling events PID
MYC pathway0001191 Interleukin signaling pathway PANTHER
MYC pathway0001287 LKB1 signaling events PID
MYC pathway0001322 MAPK6/MAPK4 signaling Reactome
MYC pathway0001523 Notch signaling pathway PID
MYC pathway0001524 NOTCH1 Intracellular Domain Regulates Transcription Reactome
MYC pathway0001560 Oxidative stress response PANTHER
MYC pathway0001581 p53 pathway feedback loops 2 PANTHER
MYC pathway0001582 p73 transcription factor network PID
MYC pathway0001604 PDGF signaling pathway PANTHER
MYC pathway0001606 PDGFR-beta signaling pathway PID
MYC pathway0001714 Presenilin action in Notch and Wnt signaling PID
MYC pathway0001727 Prolactin NetPath
MYC pathway0001848 Regulation of nuclear beta catenin signaling and target gene transcription PID
MYC pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
MYC pathway0001861 Regulation of Telomerase PID
MYC pathway0002069 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome
MYC pathway0002222 TGF_beta_Receptor NetPath
MYC pathway0002388 Validated nuclear estrogen receptor alpha network PID
MYC pathway0002390 Validated targets of C-MYC transcriptional activation PID
MYC pathway0002391 Validated targets of C-MYC transcriptional repression PID
MYC pathway0002562 MAPK signaling pathway KEGG
MYC pathway0002564 ErbB signaling pathway KEGG
MYC pathway0002571 Cell cycle KEGG
MYC pathway0002587 Wnt signaling pathway KEGG
MYC pathway0002591 TGF-beta signaling pathway KEGG
MYC pathway0002606 Jak-STAT signaling pathway KEGG
MYC pathway0002656 Pathways in cancer KEGG
MYC pathway0002657 Colorectal cancer KEGG
MYC pathway0002660 Endometrial cancer KEGG
MYC pathway0002663 Thyroid cancer KEGG
MYC pathway0002666 Bladder cancer KEGG
MYC pathway0002667 Chronic myeloid leukemia KEGG
MYC pathway0002668 Acute myeloid leukemia KEGG
MYC pathway0002669 Small cell lung cancer KEGG
MYC pathway0002691 Hs_DNA_Damage_Response_(only_ATM_dependent)_WP710_79974 WikiPathways
MYC pathway0002692 Hs_TP53_Network_WP1742_71700 WikiPathways
MYC pathway0002693 Hs_Imatinib_and_Chronic_Myeloid_Leukemia_WP3640_89384 WikiPathways
MYC pathway0002697 Hs_miRNAs_involved_in_DNA_damage_response_WP1545_84697 WikiPathways
MYC pathway0002701 Hs_Association_Between_Physico-Chemical_Features_and_Toxicity_Associated_Pathways_WP3680_90113 WikiPathways
MYC pathway0002713 Hs_Gastric_Cancer_Network_2_WP2363_87523 WikiPathways
MYC pathway0002717 Hs_Hepatitis_C_and_Hepatocellular_Carcinoma_WP3646_88640 WikiPathways
MYC pathway0002719 Hs_Apoptosis_WP254_88977 WikiPathways
MYC pathway0002731 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 WikiPathways
MYC pathway0002747 Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways
MYC pathway0002837 Hs_IL-5_Signaling_Pathway_WP127_78498 WikiPathways
MYC pathway0002860 Hs_Prolactin_Signaling_Pathway_WP2037_90015 WikiPathways
MYC pathway0002866 Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 WikiPathways
MYC pathway0002872 Hs_IL-7_Signaling_Pathway_WP205_89854 WikiPathways
NR0B1 pathway0001534 Nuclear Receptor transcription pathway Reactome
NR0B1 pathway0001825 Regulation of Androgen receptor activity PID
NR0B1 pathway0002388 Validated nuclear estrogen receptor alpha network PID
NR0B1 pathway0002389 Validated nuclear estrogen receptor beta network PID
NR2E3 pathway0001534 Nuclear Receptor transcription pathway Reactome
NR2F1 pathway0001534 Nuclear Receptor transcription pathway Reactome
NR2F6 pathway0001534 Nuclear Receptor transcription pathway Reactome
NR5A2 pathway0001534 Nuclear Receptor transcription pathway Reactome
NR5A2 pathway0001835 Regulation of gene expression in early pancreatic precursor cells Reactome
NR5A2 pathway0002631 Maturity onset diabetes of the young KEGG
PAX4 pathway0001836 Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells Reactome
PAX4 pathway0002631 Maturity onset diabetes of the young KEGG
PAX5 pathway0000335 C-MYB transcription factor network PID
PAX5 pathway0001078 ID NetPath
PITX2 pathway0001848 Regulation of nuclear beta catenin signaling and target gene transcription PID
PITX2 pathway0002591 TGF-beta signaling pathway KEGG
PITX2 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
PITX2 pathway0002771 Hs_BMP_Signaling_Pathway_in_Eyelid_Development_WP3927_90735 WikiPathways
POLR3A pathway0000532 Cytosolic sensors of pathogen-associated DNA Reactome
POLR3A pathway0001926 RNA Polymerase III Abortive And Retractive Initiation Reactome
POLR3A pathway0001927 RNA Polymerase III Chain Elongation Reactome
POLR3A pathway0001928 RNA Polymerase III Transcription Initiation From Type 1 Promoter Reactome
POLR3A pathway0001929 RNA Polymerase III Transcription Initiation From Type 2 Promoter Reactome
POLR3A pathway0001930 RNA Polymerase III Transcription Initiation From Type 3 Promoter Reactome
POLR3A pathway0001931 RNA Polymerase III Transcription Termination Reactome
POLR3A pathway0002492 Purine metabolism KEGG
POLR3A pathway0002494 Pyrimidine metabolism KEGG
POLR3A pathway0002605 Cytosolic DNA-sensing pathway KEGG
POU2F2 pathway0000271 BCR signaling pathway PID
POU2F2 pathway0001921 RNA polymerase II transcribes snRNA genes Reactome
POU2F2 pathway0002393 Validated transcriptional targets of deltaNp63 isoforms PID
RARA pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
RARA pathway0000842 FSH NetPath
RARA pathway0001126 IL3 NetPath
RARA pathway0001534 Nuclear Receptor transcription pathway Reactome
RARA pathway0001883 Retinoic acid receptors-mediated signaling PID
RARA pathway0001947 RXR and RAR heterodimerization with other nuclear receptor PID
RARA pathway0002028 Signaling by Retinoic Acid Reactome
RARA pathway0002656 Pathways in cancer KEGG
RARA pathway0002668 Acute myeloid leukemia KEGG
RARA pathway0002686 Hs_Tryptophan_metabolism_WP465_85055 WikiPathways
RARG pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
RARG pathway0001534 Nuclear Receptor transcription pathway Reactome
RARG pathway0001883 Retinoic acid receptors-mediated signaling PID
RARG pathway0001947 RXR and RAR heterodimerization with other nuclear receptor PID
RARG pathway0002028 Signaling by Retinoic Acid Reactome
RUNX1 pathway0000176 AndrogenReceptor NetPath
RUNX1 pathway0001551 Organic cation transport Reactome
RUNX1 pathway0001799 RANKL NetPath
RUNX1 pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
RUNX1 pathway0002222 TGF_beta_Receptor NetPath
RUNX1 pathway0002393 Validated transcriptional targets of deltaNp63 isoforms PID
RUNX1 pathway0002656 Pathways in cancer KEGG
RUNX1 pathway0002667 Chronic myeloid leukemia KEGG
RUNX1 pathway0002668 Acute myeloid leukemia KEGG
RUNX2 pathway0000176 AndrogenReceptor NetPath
RUNX2 pathway0000780 FGF signaling pathway PID
RUNX2 pathway0001264 Leptin NetPath
RUNX2 pathway0001516 Notch-mediated HES/HEY network PID
RUNX2 pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
RUNX2 pathway0001857 Regulation of retinoblastoma protein PID
RUNX2 pathway0002222 TGF_beta_Receptor NetPath
RUNX2 pathway0002460 YAP1- and WWTR1 (TAZ)-stimulated gene expression Reactome
RUNX2 pathway0002709 Hs_MAPK_Signaling_Pathway_WP382_79951 WikiPathways
RUNX2 pathway0002725 Hs_Endochondral_Ossification_WP474_87977 WikiPathways
RUNX2 pathway0002726 Hs_Role_of_Osx_and_miRNAs_in_tooth_development_WP3971_91525 WikiPathways
RUNX2 pathway0002770 Hs_Bone_Morphogenic_Protein_(BMP)_Signalling_and_Regulation_WP1425_86082 WikiPathways
RUNX2 pathway0002852 Hs_Focal_Adhesion-PI3K-Akt-mTOR-signaling_pathway_WP3932_91101 WikiPathways
SOX2 pathway0000549 Deactivation of the beta-catenin transactivating complex Reactome
SOX2 pathway0001701 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Reactome
SOX2 pathway0001702 POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation Reactome
SOX2 pathway0002301 Transcriptional regulation of pluripotent stem cells Reactome
SOX2 pathway0002740 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways
SOX2 pathway0002746 Hs_Dopaminergic_Neurogenesis_WP2855_87239 WikiPathways
SOX2 pathway0002821 Hs_Wnt_Signaling_Pathway_and_Pluripotency_WP399_90291 WikiPathways
SOX2 pathway0002826 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 WikiPathways
SOX2 pathway0002841 Hs_Ectoderm_Differentiation_WP2858_89329 WikiPathways
SOX9 pathway0000549 Deactivation of the beta-catenin transactivating complex Reactome
SOX9 pathway0002222 TGF_beta_Receptor NetPath
SOX9 pathway0002747 Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways
SOX9 pathway0002791 Hs_Spinal_Cord_Injury_WP2431_87678 WikiPathways
SP1 pathway0000069 Activation of gene expression by SREBF (SREBP) Reactome
SP1 pathway0000176 AndrogenReceptor NetPath
SP1 pathway0000187 AP-1 transcription factor network PID
SP1 pathway0000335 C-MYB transcription factor network PID
SP1 pathway0000608 Direct p53 effectors PID
SP1 pathway0000648 E2F transcription factor network PID
SP1 pathway0000658 EGFR1 NetPath
SP1 pathway0000824 FOXA1 transcription factor network PID
SP1 pathway0000825 FOXA2 and FOXA3 transcription factor networks PID
SP1 pathway0000826 FOXM1 transcription factor network PID
SP1 pathway0001021 HIF-1-alpha transcription factor network PID
SP1 pathway0001022 HIF-2-alpha transcription factor network PID
SP1 pathway0001046 Huntington disease PANTHER
SP1 pathway0001122 IL2 signaling events mediated by STAT5 PID
SP1 pathway0001127 IL4-mediated signaling events PID
SP1 pathway0001264 Leptin NetPath
SP1 pathway0001543 Oncogene Induced Senescence Reactome
SP1 pathway0001582 p73 transcription factor network PID
SP1 pathway0001704 PPARA activates gene expression Reactome
SP1 pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
SP1 pathway0001861 Regulation of Telomerase PID
SP1 pathway0001921 RNA polymerase II transcribes snRNA genes Reactome
SP1 pathway0002069 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome
SP1 pathway0002222 TGF_beta_Receptor NetPath
SP1 pathway0002391 Validated targets of C-MYC transcriptional repression PID
SP1 pathway0002392 Validated transcriptional targets of AP1 family members Fra1 and Fra2 PID
SP1 pathway0002394 Validated transcriptional targets of TAp63 isoforms PID
SP1 pathway0002591 TGF-beta signaling pathway KEGG
SP1 pathway0002642 Huntington's disease KEGG
SP1 pathway0002699 Hs_Corticotropin-releasing_hormone_signaling_pathway_WP2355_90017 WikiPathways
SP1 pathway0002712 Hs_Leptin_signaling_pathway_WP2034_89856 WikiPathways
SP1 pathway0002718 Hs_Interleukin-11_Signaling_Pathway_WP2332_79525 WikiPathways
SP1 pathway0002731 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 WikiPathways
SP1 pathway0002811 Hs_Estrogen_signaling_pathway_WP712_78491 WikiPathways
SP1 pathway0002812 Hs_Sudden_Infant_Death_Syndrome_(SIDS)_Susceptibility_Pathways_WP706_86078 WikiPathways
SP1 pathway0002853 Hs_TGF-beta_Signaling_Pathway_WP366_90028 WikiPathways
SP1 pathway0002862 Hs_AGE-RAGE_pathway_WP2324_89798 WikiPathways
SP1 pathway0002863 Hs_Androgen_receptor_signaling_pathway_WP138_79958 WikiPathways
SP1 pathway0002866 Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 WikiPathways
SRY pathway0000176 AndrogenReceptor NetPath
SRY pathway0000549 Deactivation of the beta-catenin transactivating complex Reactome
SRY pathway0001825 Regulation of Androgen receptor activity PID
STAT1 pathway0000177 Angiogenesis PANTHER
STAT1 pathway0000270 BCR NetPath
STAT1 pathway0000513 CXCR4-mediated signaling events PID
STAT1 pathway0000633 Downstream signal transduction Reactome
STAT1 pathway0000652 EGF receptor signaling pathway PANTHER
STAT1 pathway0000658 EGFR1 NetPath
STAT1 pathway0000687 EPO signaling pathway PID
STAT1 pathway0000688 EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ( EPO signaling pathway(JAK2 STAT1 STAT3 STAT5) ) INOH
STAT1 pathway0000692 ErbB1 downstream signaling PID
STAT1 pathway0000780 FGF signaling pathway PID
STAT1 pathway0000899 Gene expression of SOCS by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0000900 Gene expression of SOCS1 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0000901 Gene expression of SOCS3 by STAT dimer ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0000916 Glucocorticoid receptor regulatory network PID
STAT1 pathway0000966 GMCSF-mediated signaling events PID
STAT1 pathway0000976 Growth hormone receptor signaling Reactome
STAT1 pathway0001079 IFN-gamma pathway PID
STAT1 pathway0001080 IFN alpha signaling pathway((JAK1 TYK2 STAT1 STAT2) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) ) INOH
STAT1 pathway0001081 IFN alpha signaling pathway(JAK1 TYK2 STAT1 STAT3) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) ) INOH
STAT1 pathway0001082 IFN alpha signaling pathway(JAK1 TYK2 STAT1) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) ) INOH
STAT1 pathway0001084 IFN gamma signaling pathway(JAK1 JAK2 STAT1) ( IFN gamma signaling(JAK1 JAK2 STAT1) ) INOH
STAT1 pathway0001109 IL-5 signaling pathway(JAK1 JAK2 STAT1 STAT5) ( IL-5 signaling(JAK1 JAK2 STAT1 STAT5) ) INOH
STAT1 pathway0001112 IL-7 NetPath
STAT1 pathway0001116 IL12-mediated signaling events PID
STAT1 pathway0001119 IL2-mediated signaling events PID
STAT1 pathway0001120 IL2 NetPath
STAT1 pathway0001123 IL23-mediated signaling events PID
STAT1 pathway0001124 IL27-mediated signaling events PID
STAT1 pathway0001128 IL4 NetPath
STAT1 pathway0001130 IL5 NetPath
STAT1 pathway0001131 IL6-mediated signaling events PID
STAT1 pathway0001132 IL6 NetPath
STAT1 pathway0001135 IL9 NetPath
STAT1 pathway0001179 Interferon-gamma signaling pathway PANTHER
STAT1 pathway0001180 Interferon alpha/beta signaling Reactome
STAT1 pathway0001181 Interferon gamma signaling Reactome
STAT1 pathway0001188 Interleukin-6 signaling Reactome
STAT1 pathway0001191 Interleukin signaling pathway PANTHER
STAT1 pathway0001219 ISG15 antiviral mechanism Reactome
STAT1 pathway0001226 JAK-STAT pathway and regulation pathway ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0001228 JAK/STAT signaling pathway PANTHER
STAT1 pathway0001246 KitReceptor NetPath
STAT1 pathway0001264 Leptin NetPath
STAT1 pathway0001560 Oxidative stress response PANTHER
STAT1 pathway0001604 PDGF signaling pathway PANTHER
STAT1 pathway0001606 PDGFR-beta signaling pathway PID
STAT1 pathway0001697 Positive regulation of (Transcription of SOCS by STAT dimer) in JAK STAT pathway ( JAK-STAT pathway and regulation pathway Diagram ) INOH
STAT1 pathway0001727 Prolactin NetPath
STAT1 pathway0001799 RANKL NetPath
STAT1 pathway0001805 Ras Pathway PANTHER
STAT1 pathway0001840 Regulation of IFNA signaling Reactome
STAT1 pathway0001841 Regulation of IFNG signaling Reactome
STAT1 pathway0002000 SHP2 signaling PID
STAT1 pathway0002010 Signaling by cytosolic FGFR1 fusion mutants Reactome
STAT1 pathway0002030 Signaling by SCF-KIT Reactome
STAT1 pathway0002039 Signaling events mediated by Stem cell factor receptor (c-Kit) PID
STAT1 pathway0002040 Signaling events mediated by TCPTP PID
STAT1 pathway0002199 TCR NetPath
STAT1 pathway0002246 TNF receptor signaling pathway PID
STAT1 pathway0002249 TNFalpha NetPath
STAT1 pathway0002354 TSH NetPath
STAT1 pathway0002355 TSLP NetPath
STAT1 pathway0002568 Chemokine signaling pathway KEGG
STAT1 pathway0002602 Toll-like receptor signaling pathway KEGG
STAT1 pathway0002606 Jak-STAT signaling pathway KEGG
STAT1 pathway0002649 Leishmaniasis KEGG
STAT1 pathway0002652 Toxoplasmosis KEGG
STAT1 pathway0002655 Hepatitis C KEGG
STAT1 pathway0002656 Pathways in cancer KEGG
STAT1 pathway0002659 Pancreatic cancer KEGG
STAT1 pathway0002682 Hs_Interferon_type_I_signaling_pathways_WP585_85198 WikiPathways
STAT1 pathway0002689 Hs_Cytokines_and_Inflammatory_Response_WP530_79331 WikiPathways
STAT1 pathway0002712 Hs_Leptin_signaling_pathway_WP2034_89856 WikiPathways
STAT1 pathway0002718 Hs_Interleukin-11_Signaling_Pathway_WP2332_79525 WikiPathways
STAT1 pathway0002725 Hs_Endochondral_Ossification_WP474_87977 WikiPathways
STAT1 pathway0002731 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 WikiPathways
STAT1 pathway0002735 Hs_PDGF_Pathway_WP2526_82681 WikiPathways
STAT1 pathway0002740 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways
STAT1 pathway0002743 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways
STAT1 pathway0002751 Hs_Integrated_Cancer_Pathway_WP1971_82939 WikiPathways
STAT1 pathway0002760 Hs_Oncostatin_M_Signaling_Pathway_WP2374_73668 WikiPathways
STAT1 pathway0002813 Hs_One_carbon_metabolism_and_related_pathways_WP3940_91096 WikiPathways
STAT1 pathway0002829 Hs_Kit_receptor_signaling_pathway_WP304_78799 WikiPathways
STAT1 pathway0002837 Hs_IL-5_Signaling_Pathway_WP127_78498 WikiPathways
STAT1 pathway0002844 Hs_IL-2_Signaling_Pathway_WP49_91243 WikiPathways
STAT1 pathway0002858 Hs_IL-6_signaling_pathway_WP364_89832 WikiPathways
STAT1 pathway0002860 Hs_Prolactin_Signaling_Pathway_WP2037_90015 WikiPathways
STAT1 pathway0002864 Hs_IL-4_Signaling_Pathway_WP395_89828 WikiPathways
STAT1 pathway0002865 Hs_Brain-Derived_Neurotrophic_Factor_(BDNF)_signaling_pathway_WP2380_89803 WikiPathways
STAT1 pathway0002866 Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 WikiPathways
STAT1 pathway0002879 Hs_IL-9_Signaling_Pathway_WP22_79264 WikiPathways
STAT1 pathway0002880 Hs_Insulin_signalling_in_adipocytes_(diabetic_condition)_WP3635_86059 WikiPathways
STAT1 pathway0002881 Hs_Insulin_signalling_in_adipocytes_(normal_condition)_WP3634_86060 WikiPathways
TBX5 pathway0001649 Physiological factors Reactome
TBX5 pathway0002460 YAP1- and WWTR1 (TAZ)-stimulated gene expression Reactome
TBX5 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
TCF3 pathway0000393 CDO in myogenesis Reactome
TCF3 pathway0001078 ID NetPath
TCF3 pathway0001516 Notch-mediated HES/HEY network PID
TCF3 pathway0001517 Notch NetPath
TCF3 pathway0001574 p38 signaling mediated by MAPKAP kinases PID
TCF3 pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
TCF3 pathway0002439 Wnt NetPath
TCF3 pathway0002841 Hs_Ectoderm_Differentiation_WP2858_89329 WikiPathways
TFAP2C pathway0002394 Validated transcriptional targets of TAp63 isoforms PID
TP53 pathway0000075 Activation of PUMA and translocation to mitochondria Reactome
TP53 pathway0000187 AP-1 transcription factor network PID
TP53 pathway0000196 Apoptosis signaling pathway PANTHER
TP53 pathway0000226 Association of TriC/CCT with target proteins during biosynthesis Reactome
TP53 pathway0000253 Aurora A signaling PID
TP53 pathway0000257 Autodegradation of the E3 ubiquitin ligase COP1 Reactome
TP53 pathway0000267 BARD1 signaling events PID
TP53 pathway0000608 Direct p53 effectors PID
TP53 pathway0000617 DNA Damage/Telomere Stress Induced Senescence Reactome
TP53 pathway0000658 EGFR1 NetPath
TP53 pathway0000747 Factors involved in megakaryocyte development and platelet production Reactome
TP53 pathway0000814 Formation of Senescence-Associated Heterochromatin Foci (SAHF) Reactome
TP53 pathway0000865 G2/M Checkpoints Reactome
TP53 pathway0000866 G2/M DNA damage checkpoint Reactome
TP53 pathway0000916 Glucocorticoid receptor regulatory network PID
TP53 pathway0001046 Huntington disease PANTHER
TP53 pathway0001072 Hypoxic and oxygen homeostasis regulation of HIF-1-alpha PID
TP53 pathway0001287 LKB1 signaling events PID
TP53 pathway0001543 Oncogene Induced Senescence Reactome
TP53 pathway0001559 Oxidative Stress Induced Senescence Reactome
TP53 pathway0001577 p53 pathway by glucose deprivation PANTHER
TP53 pathway0001578 p53 pathway PANTHER
TP53 pathway0001579 p53 pathway PID
TP53 pathway0001580 P53 pathway feedback loops 1 PANTHER
TP53 pathway0001581 p53 pathway feedback loops 2 PANTHER
TP53 pathway0001583 p75(NTR)-mediated signaling PID
TP53 pathway0001687 PLK3 signaling events PID
TP53 pathway0001711 Pre-NOTCH Transcription and Translation Reactome
TP53 pathway0001812 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Reactome
TP53 pathway0001863 Regulation of TP53 Activity through Acetylation Reactome
TP53 pathway0001864 Regulation of TP53 Activity through Association with Co-factors Reactome
TP53 pathway0001865 Regulation of TP53 Activity through Methylation Reactome
TP53 pathway0001866 Regulation of TP53 Activity through Phosphorylation Reactome
TP53 pathway0001867 Regulation of TP53 Degradation Reactome
TP53 pathway0002035 Signaling events mediated by HDAC Class III PID
TP53 pathway0002044 Signaling mediated by p38-alpha and p38-beta PID
TP53 pathway0002101 Stabilization of p53 Reactome
TP53 pathway0002127 SUMOylation of transcription factors Reactome
TP53 pathway0002222 TGF_beta_Receptor NetPath
TP53 pathway0002230 The role of GTSE1 in G2/M progression after G2 checkpoint Reactome
TP53 pathway0002249 TNFalpha NetPath
TP53 pathway0002269 TP53 Regulates Metabolic Genes Reactome
TP53 pathway0002270 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain Reactome
TP53 pathway0002271 TP53 Regulates Transcription of Caspase Activators and Caspases Reactome
TP53 pathway0002272 TP53 Regulates Transcription of Death Receptors and Ligands Reactome
TP53 pathway0002273 TP53 Regulates Transcription of DNA Repair Genes Reactome
TP53 pathway0002274 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Reactome
TP53 pathway0002275 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Reactome
TP53 pathway0002276 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Reactome
TP53 pathway0002277 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain Reactome
TP53 pathway0002390 Validated targets of C-MYC transcriptional activation PID
TP53 pathway0002418 Vinblastine Action Pathway SMPDB
TP53 pathway0002419 Vincristine Action Pathway SMPDB
TP53 pathway0002420 Vindesine Action Pathway SMPDB
TP53 pathway0002421 Vinorelbine Action Pathway SMPDB
TP53 pathway0002562 MAPK signaling pathway KEGG
TP53 pathway0002571 Cell cycle KEGG
TP53 pathway0002575 p53 signaling pathway KEGG
TP53 pathway0002584 Apoptosis KEGG
TP53 pathway0002587 Wnt signaling pathway KEGG
TP53 pathway0002617 Neurotrophin signaling pathway KEGG
TP53 pathway0002641 Amyotrophic lateral sclerosis (ALS) KEGG
TP53 pathway0002642 Huntington's disease KEGG
TP53 pathway0002655 Hepatitis C KEGG
TP53 pathway0002656 Pathways in cancer KEGG
TP53 pathway0002657 Colorectal cancer KEGG
TP53 pathway0002659 Pancreatic cancer KEGG
TP53 pathway0002660 Endometrial cancer KEGG
TP53 pathway0002661 Glioma KEGG
TP53 pathway0002662 Prostate cancer KEGG
TP53 pathway0002663 Thyroid cancer KEGG
TP53 pathway0002664 Basal cell carcinoma KEGG
TP53 pathway0002665 Melanoma KEGG
TP53 pathway0002666 Bladder cancer KEGG
TP53 pathway0002667 Chronic myeloid leukemia KEGG
TP53 pathway0002669 Small cell lung cancer KEGG
TP53 pathway0002670 Non-small cell lung cancer KEGG
TP53 pathway0002680 Hs_Cell_Cycle_WP179_89516 WikiPathways
TP53 pathway0002686 Hs_Tryptophan_metabolism_WP465_85055 WikiPathways
TP53 pathway0002690 Hs_ErbB_Signaling_Pathway_WP673_91869 WikiPathways
TP53 pathway0002691 Hs_DNA_Damage_Response_(only_ATM_dependent)_WP710_79974 WikiPathways
TP53 pathway0002692 Hs_TP53_Network_WP1742_71700 WikiPathways
TP53 pathway0002694 Hs_DNA_Damage_Response_WP707_82937 WikiPathways
TP53 pathway0002695 Hs_miRNA_Regulation_of_DNA_Damage_Response_WP1530_84694 WikiPathways
TP53 pathway0002710 Hs_Nuclear_Receptors_in_Lipid_Metabolism_and_Toxicity_WP299_89331 WikiPathways
TP53 pathway0002713 Hs_Gastric_Cancer_Network_2_WP2363_87523 WikiPathways
TP53 pathway0002717 Hs_Hepatitis_C_and_Hepatocellular_Carcinoma_WP3646_88640 WikiPathways
TP53 pathway0002722 Hs_Senescence_and_Autophagy_in_Cancer_WP615_81193 WikiPathways
TP53 pathway0002731 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 WikiPathways
TP53 pathway0002734 Hs_Apoptosis_Modulation_and_Signaling_WP1772_91293 WikiPathways
TP53 pathway0002738 Hs_Alzheimers_Disease_WP2059_87372 WikiPathways
TP53 pathway0002739 Hs_Copper_homeostasis_WP3286_89205 WikiPathways
TP53 pathway0002751 Hs_Integrated_Cancer_Pathway_WP1971_82939 WikiPathways
TP53 pathway0002752 Hs_ATM_Signaling_Pathway_WP2516_90247 WikiPathways
TP53 pathway0002753 Hs_DNA_IR-Double_Strand_Breaks_(DSBs)_and_cellular_response_via_ATM_WP3959_91367 WikiPathways
TP53 pathway0002757 Hs_Pathways_Affected_in_Adenoid_Cystic_Carcinoma_WP3651_89271 WikiPathways
TP53 pathway0002766 Hs_LncRNA-mediated_mechanisms_of_therapeutic_resistance_WP3672_87395 WikiPathways
TP53 pathway0002775 Hs_Bladder_Cancer_WP2828_89143 WikiPathways
TP53 pathway0002776 Hs_Signaling_Pathways_in_Glioblastoma_WP2261_89520 WikiPathways
TP53 pathway0002805 Hs_Steroid_Biosynthesis_WP496_69016 WikiPathways
TP53 pathway0002807 Hs_Retinoblastoma_(RB)_in_Cancer_WP2446_87639 WikiPathways
TP53 pathway0002840 Hs_G1_to_S_cell_cycle_control_WP45_80001 WikiPathways
ZBTB7B pathway0002841 Hs_Ectoderm_Differentiation_WP2858_89329 WikiPathways
ZNF143 pathway0001921 RNA polymerase II transcribes snRNA genes Reactome
ZNF143 pathway0001926 RNA Polymerase III Abortive And Retractive Initiation Reactome
ZNF143 pathway0001930 RNA Polymerase III Transcription Initiation From Type 3 Promoter Reactome
ZNF263 pathway0000905 Generic Transcription Pathway Reactome