General Details

Super-enhancer:SE_00_02600416
Genomic Locus: chr3: 48126304-48131501
Size/Length:5197bp
Conservation:0.0570614
BioSample Type:Tissue
Tissue Type:Muscle of trunk
Sample Name:muscle-of-trunk
Source:Roadmap
Element:2
Rank:416
ChIP Density(Case):15574.3696
ChIP Density(Input):674.0509

Super-enhancer Associated Network


* The complex regulatory networks formed by this SE , SE associated genes , TFs binding to the SE and their upstream pathways can be interactively visualized.


Fimo:
SE-Gene Linking Strategies:
Pathway Enriciment Threshold:
Top Pathway:
 



Super-enhancer Associated Statistics

Associated Gene Details

ROSE Overlap:MAP4
ROSE Proximal:.
ROSE Closest:MAP4
The Closest Active:MAP4

Factors Binding to Super-enhancer




Using these SE element regions to analyze by online tools GREAT *The TFs binding to this SE identified by ChIP-seq.

Chrome Element_Start Element_End TF TF Source TF_Start TF_End TF Class Master TF

Using these SE element regions to analyze by online tools GREAT * The TFs binding to this SE predicted by Motif.

Chrome Element_Start Element_End TF Database TF_Start TF_End Score P_Value TF Class Master TF
chr3 48127591 48131501 BBX Transfac.V$BBX_04 48128518 48128534 15.44250 2.94e-08 Other all-alpha-helical DNA-binding domains N
chr3 48127591 48131501 BBX Uniprobe.UP00012_2 48128518 48128534 15.40230 2.99e-08 Other all-alpha-helical DNA-binding domains N
chr3 48127591 48131501 DLX1 Transfac.V$DLX1_01 48131038 48131051 16.37370 4.21e-07 Helix-turn-helix domains N
chr3 48127591 48131501 DLX1 Homeodomain.UP00202_1 48131038 48131051 16.38180 4.18e-07 Helix-turn-helix domains N
chr3 48127591 48131501 DLX1 Uniprobe.UP00202_1 48131038 48131051 16.38180 4.18e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXA1 JASPAR2014.MA0148.3 48128342 48128356 16.65310 8.56e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXA2 JASPAR2014.MA0047.2 48128346 48128357 17.03030 5.37e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXA2 Uniprobe.UP00073_1 48128341 48128357 17.20910 5.42e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXB1 Transfac.V$FOXB1_01 48127787 48127800 20.20970 8.6e-08 Helix-turn-helix domains N
chr3 48127591 48131501 FOXB1 Jolma2013.FOXB1_DBD 48127787 48127800 20.16000 8.6e-08 Helix-turn-helix domains N
chr3 48127591 48131501 FOXC1 Transfac.V$FOXC1_02 48128127 48128139 19.69090 9.54e-08 Helix-turn-helix domains N
chr3 48127591 48131501 FOXC1 Transfac.V$FOXC1_02 48128131 48128143 19.69090 9.54e-08 Helix-turn-helix domains N
chr3 48127591 48131501 FOXC1 Jolma2013.FOXC1_DBD 48128127 48128139 19.64650 9.54e-08 Helix-turn-helix domains N
chr3 48127591 48131501 FOXC1 Jolma2013.FOXC1_DBD 48128131 48128143 19.64650 9.54e-08 Helix-turn-helix domains N
chr3 48127591 48131501 FOXC2 Transfac.V$FOXC2_03 48128344 48128355 17.04000 1.99e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXC2 Jolma2013.FOXC2_DBD_3 48128344 48128355 16.97300 1.99e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXJ1 Transfac.V$FOXJ1_03 48128340 48128355 16.69880 1.39e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXJ1 Uniprobe.UP00041_1 48128340 48128355 16.63200 1.34e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXJ2 Transfac.V$FOXJ2_01 48128123 48128140 17.92220 1.49e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXJ2 Transfac.V$FOXJ2_01 48128127 48128144 18.62220 4.09e-08 Helix-turn-helix domains N
chr3 48127591 48131501 FOXJ2 Transfac.V$FOXJ2_01 48128131 48128148 16.84440 7.18e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXJ3 Uniprobe.UP00039_1 48128341 48128357 18.03030 1.05e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXL1 Transfac.V$FOXL1_06 48128128 48128140 17.14470 5.91e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXL1 Transfac.V$FOXL1_06 48128132 48128144 17.14470 5.91e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXL1 Jolma2013.FOXL1_full_2 48128128 48128140 17.08080 5.91e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXL1 Jolma2013.FOXL1_full_2 48128132 48128144 17.08080 5.91e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXO4 Transfac.V$FOXO4_02 48128342 48128355 17.40400 9.96e-07 Helix-turn-helix domains N
chr3 48126304 48127501 FOXP1 Transfac.V$FOXP1_01 48126681 48126700 5.19277 4.84e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXP1 Transfac.V$FOXP1_01 48127822 48127841 5.86747 4.32e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXP1 Transfac.V$FOXP1_01 48128125 48128144 4.95181 5.11e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXP1 JASPAR2014.MA0481.1 48128343 48128357 16.91550 8.96e-07 Helix-turn-helix domains N
chr3 48127591 48131501 FOXP2 JASPAR2014.MA0593.1 48128344 48128354 16.80300 2.04e-07 Helix-turn-helix domains N
chr3 48126304 48127501 HES5 Transfac.V$HES5_01 48127406 48127417 18.91940 5.99e-07 Basic domains N
chr3 48126304 48127501 HES5 Transfac.V$HES5_01 48127406 48127417 18.83870 6.64e-07 Basic domains N
chr3 48126304 48127501 HES5 Jolma2013.HES5_DBD 48127406 48127417 18.87880 5.99e-07 Basic domains N
chr3 48126304 48127501 HES5 Jolma2013.HES5_DBD 48127406 48127417 18.78790 6.64e-07 Basic domains N
chr3 48126304 48127501 HES7 Transfac.V$HES7_01 48127406 48127417 18.68970 4.69e-07 Basic domains N
chr3 48126304 48127501 HES7 Transfac.V$HES7_01 48127406 48127417 19.13790 3.36e-07 Basic domains N
chr3 48126304 48127501 HES7 Jolma2013.HES7_DBD 48127406 48127417 18.65660 4.69e-07 Basic domains N
chr3 48126304 48127501 HES7 Jolma2013.HES7_DBD 48127406 48127417 19.08080 3.36e-07 Basic domains N
chr3 48127591 48131501 HLX Transfac.V$HB24_01 48131041 48131055 16.32880 3.48e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HLX Transfac.V$HB24_01 48131042 48131056 16.13700 4.61e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HLX Homeodomain.UP00225_1 48131041 48131055 16.31510 3.4e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HLX Homeodomain.UP00225_1 48131042 48131056 16.14380 4.34e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HLX Uniprobe.UP00225_1 48131041 48131055 16.31510 3.4e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HLX Uniprobe.UP00225_1 48131042 48131056 16.14380 4.34e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HNF1A Transfac.V$HNF1_02 48131080 48131096 15.99000 8.92e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HNF1A Transfac.V$TCF1_06 48131080 48131096 17.06020 9.35e-08 Helix-turn-helix domains N
chr3 48127591 48131501 HNF1A Transfac.V$TCF1_06 48131081 48131097 17.81930 1.84e-08 Helix-turn-helix domains N
chr3 48127591 48131501 HNF1A Homeodomain.UP00089_1 48131080 48131096 15.99100 8.74e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HNF1A Uniprobe.UP00089_1 48131080 48131096 16.95500 1e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HNF1A Uniprobe.UP00089_1 48131081 48131097 17.76580 1.78e-08 Helix-turn-helix domains N
chr3 48127591 48131501 HNF1A Uniprobe.UP00089_3 48131080 48131096 15.99100 8.74e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HOXA10 Transfac.V$HOXA10_04 48128210 48128220 14.63460 6.12e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HOXA10 Jolma2013.HOXA10_DBD_2 48128210 48128220 14.60000 6.12e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HOXC10 Transfac.V$HOXC10_04 48128210 48128219 14.11540 7.98e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HOXC10 Transfac.V$HOXC10_07 48128210 48128219 15.94550 7.98e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HOXC10 Jolma2013.HOXC10_DBD_2 48128210 48128219 14.05000 7.98e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HOXC10 Jolma2013.Hoxc10_DBD_2 48128210 48128219 15.86870 7.98e-07 Helix-turn-helix domains N
chr3 48127591 48131501 HOXC11 Jolma2013.HOXC11_DBD_2 48128210 48128220 14.35000 3.99e-07 Helix-turn-helix domains N
chr3 48127591 48131501 LHX3 JASPAR2014.MA0135.1 48131041 48131053 19.93940 1.29e-07 Helix-turn-helix domains N
chr3 48127591 48131501 MAZ Transfac.V$MAZ_Q6_01 48129657 48129670 18.71430 3.64e-08 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 MECP2 Transfac.V$MECP2_01 48131096 48131110 16.01000 1.7e-07 TcoF-DB_TF N
chr3 48127591 48131501 MEF2C JASPAR2014.MA0497.1 48128884 48128898 17.05170 8.41e-07 alpha-Helices exposed by beta-structures Y
chr3 48127591 48131501 MTF1 Transfac.V$MTF1_06 48131372 48131385 12.46120 4.01e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 MTF1 Uniprobe.UP00097_2 48131372 48131385 12.42010 3.95e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 MYB JASPAR2014.MA0100.2 48131066 48131075 15.54840 9.51e-07 Helix-turn-helix domains N
chr3 48127591 48131501 NEUROD1 Transfac.V$NEUROD_02 48129155 48129166 15.07040 6.49e-08 Basic domains N
chr3 48126304 48127501 NFATC1 Transfac.V$NFATC1_01 48126909 48126928 18.60000 3.17e-07 Immunoglobulin fold N
chr3 48126304 48127501 NFATC1 Jolma2013.NFATC1_full 48126909 48126928 18.62630 3.1e-07 Immunoglobulin fold N
chr3 48127591 48131501 NKX2-8 Transfac.V$NKX29_01 48128368 48128384 16.55450 9.26e-07 Helix-turn-helix domains N
chr3 48127591 48131501 NKX2-8 Homeodomain.UP00119_1 48128368 48128384 16.52680 9.66e-07 Helix-turn-helix domains N
chr3 48127591 48131501 NKX2-8 Uniprobe.UP00119_1 48128368 48128384 16.52680 9.66e-07 Helix-turn-helix domains N
chr3 48127591 48131501 NKX3-1 Transfac.V$NKX31_02 48128465 48128481 16.62650 8.51e-07 Helix-turn-helix domains N
chr3 48127591 48131501 NKX3-1 Uniprobe.UP00017_1 48128465 48128481 16.47470 9.46e-07 Helix-turn-helix domains N
chr3 48127591 48131501 NKX6-1 Transfac.V$NKX61_02 48131040 48131055 18.03030 2.4e-07 Helix-turn-helix domains N
chr3 48127591 48131501 NKX6-1 Homeodomain.UP00200_2 48131040 48131055 18.00000 2.45e-07 Helix-turn-helix domains N
chr3 48127591 48131501 NKX6-1 Uniprobe.UP00200_2 48131040 48131055 18.00000 2.45e-07 Helix-turn-helix domains N
chr3 48126304 48127501 NR2F6 Jolma2013.Nr2f6_DBD 48127195 48127209 16.11110 3.89e-07 Zinc-coordinating DNA-binding domains N
chr3 48126304 48127501 PITX2 Transfac.V$PITX2_Q2 48127152 48127162 16.56360 4.36e-07 Helix-turn-helix domains N
chr3 48126304 48127501 PITX2 Transfac.V$PITX2_Q2 48127287 48127297 16.09090 8.91e-07 Helix-turn-helix domains N
chr3 48127591 48131501 PITX2 Transfac.V$PITX2_Q2 48127867 48127877 16.09090 8.91e-07 Helix-turn-helix domains N
chr3 48127591 48131501 PITX2 Transfac.V$PITX2_Q2 48131128 48131138 16.09090 8.91e-07 Helix-turn-helix domains N
chr3 48127591 48131501 PITX2 Transfac.V$PITX2_Q2 48131248 48131258 16.09090 8.91e-07 Helix-turn-helix domains N
chr3 48126304 48127501 PITX2 Transfac.V$PITX2_Q6 48127152 48127161 15.07070 9.1e-07 Helix-turn-helix domains N
chr3 48126304 48127501 PITX2 Transfac.V$PITX2_Q6 48127287 48127296 15.07070 9.1e-07 Helix-turn-helix domains N
chr3 48127591 48131501 PITX2 Transfac.V$PITX2_Q6 48127867 48127876 15.07070 9.1e-07 Helix-turn-helix domains N
chr3 48127591 48131501 PITX2 Transfac.V$PITX2_Q6 48131128 48131137 15.07070 9.1e-07 Helix-turn-helix domains N
chr3 48127591 48131501 PITX2 Transfac.V$PITX2_Q6 48131248 48131257 15.07070 9.1e-07 Helix-turn-helix domains N
chr3 48126304 48127501 POLR3A Transfac.V$RPC155_01 48127199 48127214 23.34400 4.74e-10 ENCODE_TF N
chr3 48127591 48131501 POLR3A Transfac.V$RPC155_01 48127916 48127931 20.99200 2.58e-08 ENCODE_TF N
chr3 48127591 48131501 POLR3A Transfac.V$RPC155_01 48131160 48131175 17.88000 4.81e-07 ENCODE_TF N
chr3 48127591 48131501 POU1F1 Transfac.V$POU1F1_Q6 48128358 48128367 16.05050 7.98e-07 Helix-turn-helix domains N
chr3 48127591 48131501 POU1F1 Homeodomain.UP00158_1 48131041 48131057 19.15970 7.04e-08 Helix-turn-helix domains N
chr3 48127591 48131501 POU1F1 Uniprobe.UP00158_1 48131041 48131057 19.15970 7.04e-08 Helix-turn-helix domains N
chr3 48127591 48131501 POU2F1 Homeodomain.UP00254_1 48131044 48131059 16.60360 4.59e-07 Helix-turn-helix domains N
chr3 48127591 48131501 POU2F1 Uniprobe.UP00254_1 48131044 48131059 16.60360 4.59e-07 Helix-turn-helix domains N
chr3 48127591 48131501 POU3F4 Transfac.V$BRN4_01 48131041 48131057 18.17360 2.88e-07 Helix-turn-helix domains N
chr3 48127591 48131501 POU3F4 Homeodomain.UP00105_1 48131041 48131057 18.11890 2.98e-07 Helix-turn-helix domains N
chr3 48127591 48131501 POU3F4 Uniprobe.UP00105_1 48131041 48131057 18.11890 2.98e-07 Helix-turn-helix domains N
chr3 48126304 48127501 RARG Jolma2013.RARG_DBD 48127195 48127211 14.57580 9.49e-07 Zinc-coordinating DNA-binding domains N
chr3 48126304 48127501 RARG Jolma2013.Rarg_DBD 48127195 48127210 16.27270 3.96e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SLC20A1 Transfac.V$PIT1_01 48131040 48131056 16.63890 9.34e-07 UNKNOW N
chr3 48127591 48131501 SLC20A1 Transfac.V$PIT1_01 48131041 48131057 19.18750 7e-08 UNKNOW N
chr3 48126304 48127501 SOX12 Transfac.V$SOX12_03 48126448 48126461 17.66270 2.15e-08 Other all-alpha-helical DNA-binding domains Y
chr3 48126304 48127501 SOX12 Uniprobe.UP00101_1 48126448 48126461 17.61260 2.15e-08 Other all-alpha-helical DNA-binding domains Y
chr3 48126304 48127501 SOX18 Transfac.V$SOX18_03 48126446 48126461 15.72290 2.92e-07 Other all-alpha-helical DNA-binding domains N
chr3 48126304 48127501 SOX18 Uniprobe.UP00064_1 48126446 48126461 15.65600 3.03e-07 Other all-alpha-helical DNA-binding domains N
chr3 48127591 48131501 SOX9 Transfac.V$SOX9_B1 48128232 48128245 15.34940 8.79e-07 Other all-alpha-helical DNA-binding domains N
chr3 48127591 48131501 SP1 Transfac.V$SP1_02 48129024 48129034 16.77480 6.06e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP1 Transfac.V$SP1_Q4_01 48129024 48129036 15.50650 6.53e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP1 Transfac.V$SP1_Q4_01 48130371 48130383 15.54550 5.97e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP1 Transfac.V$SP1_Q4_01 48130799 48130811 15.59740 5.78e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP1 Transfac.V$SP1_Q6 48129024 48129036 16.38960 3.78e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP1 Transfac.V$SP1_Q6 48130371 48130383 16.28570 4.53e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP1 Transfac.V$SP1_Q6 48130799 48130811 16.28570 4.53e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP1 Transfac.V$SP1_Q6_02 48130367 48130383 13.78970 9.18e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP1 Transfac.V$SP1_Q6_02 48130795 48130811 15.20090 1.09e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP1 JASPAR2014.MA0079.3 48130372 48130382 16.17310 8.83e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP2 Transfac.V$SP2_Q3 48129022 48129036 19.08000 2.64e-08 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP2 Transfac.V$SP2_Q3 48130371 48130385 16.67000 7.41e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP2 Transfac.V$SP2_Q3_01 48130369 48130383 17.11000 2.57e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP2 Transfac.V$SP2_Q3_01 48130797 48130811 16.44000 6.22e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP2 JASPAR2014.MA0516.1 48130368 48130382 17.32760 3.41e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP4 Transfac.V$SP4_Q5 48129025 48129035 16.85000 9.09e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 SP4 Transfac.V$SP4_Q5 48130800 48130810 17.39000 6.06e-07 Zinc-coordinating DNA-binding domains N
chr3 48126304 48127501 SRF Transfac.V$SRF_06 48126677 48126693 16.02270 2.42e-08 alpha-Helices exposed by beta-structures N
chr3 48126304 48127501 SRF Transfac.V$SRF_06 48126678 48126694 14.92610 2.04e-07 alpha-Helices exposed by beta-structures N
chr3 48126304 48127501 SRF Transfac.V$SRF_06 48126679 48126695 14.15910 6.75e-07 alpha-Helices exposed by beta-structures N
chr3 48127591 48131501 SRF Transfac.V$SRF_06 48130993 48131009 14.31250 5.41e-07 alpha-Helices exposed by beta-structures N
chr3 48127591 48131501 SRF Transfac.V$SRF_06 48130994 48131010 14.42610 4.55e-07 alpha-Helices exposed by beta-structures N
chr3 48126304 48127501 SRF Uniprobe.UP00077_2 48126677 48126693 15.90960 2.71e-08 alpha-Helices exposed by beta-structures N
chr3 48126304 48127501 SRF Uniprobe.UP00077_2 48126678 48126694 14.83620 2.13e-07 alpha-Helices exposed by beta-structures N
chr3 48126304 48127501 SRF Uniprobe.UP00077_2 48126679 48126695 14.06780 7.09e-07 alpha-Helices exposed by beta-structures N
chr3 48127591 48131501 SRF Uniprobe.UP00077_2 48130993 48131009 14.18640 5.96e-07 alpha-Helices exposed by beta-structures N
chr3 48127591 48131501 SRF Uniprobe.UP00077_2 48130994 48131010 14.32770 4.82e-07 alpha-Helices exposed by beta-structures N
chr3 48127591 48131501 TFAP2A Transfac.V$AP2_Q3 48130606 48130621 15.80000 5.12e-07 Basic domains N
chr3 48126304 48127501 TFAP2A Transfac.V$TFAP2A_06 48126377 48126387 15.91530 5.31e-07 Basic domains N
chr3 48127591 48131501 TTF1 Transfac.V$TTF1_Q6 48130408 48130419 12.85710 2.6e-07 Helix-turn-helix domains N
chr3 48127591 48131501 YY1 Transfac.V$YY1_02 48130817 48130836 17.00000 9.29e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 ZSCAN4 Transfac.V$ZSCAN4_05 48129259 48129273 16.74140 8.04e-07 Zinc-coordinating DNA-binding domains N
chr3 48127591 48131501 ZSCAN4 Jolma2013.ZSCAN4_full 48129259 48129273 16.68690 8.12e-07 Zinc-coordinating DNA-binding domains N

The Upstream Pathways of TFs Binding to SE



TF Pathway ID Pathway Name Source
DLX1 pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
FOXA1 pathway0000176 AndrogenReceptor NetPath
FOXA1 pathway0000608 Direct p53 effectors PID
FOXA1 pathway0000824 FOXA1 transcription factor network PID
FOXA1 pathway0000825 FOXA2 and FOXA3 transcription factor networks PID
FOXA1 pathway0002740 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways
FOXA2 pathway0000824 FOXA1 transcription factor network PID
FOXA2 pathway0000825 FOXA2 and FOXA3 transcription factor networks PID
FOXA2 pathway0000996 Hedgehog signaling events mediated by Gli proteins PID
FOXA2 pathway0001834 Regulation of gene expression in beta cells Reactome
FOXA2 pathway0002631 Maturity onset diabetes of the young KEGG
FOXA2 pathway0002740 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways
FOXA2 pathway0002746 Hs_Dopaminergic_Neurogenesis_WP2855_87239 WikiPathways
FOXA2 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
FOXA2 pathway0002841 Hs_Ectoderm_Differentiation_WP2858_89329 WikiPathways
FOXC1 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
FOXC1 pathway0002826 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 WikiPathways
FOXO4 pathway0000118 AKT phosphorylates targets in the nucleus Reactome
FOXO4 pathway0000443 Class I PI3K signaling events mediated by Akt PID
FOXO4 pathway0000479 Constitutive Signaling by AKT1 E17K in Cancer Reactome
FOXO4 pathway0000658 EGFR1 NetPath
FOXO4 pathway0000827 FoxO family signaling PID
FOXO4 pathway0001132 IL6 NetPath
FOXO4 pathway0001460 Negative regulation of gene expression ( Insulin receptor signaling (D. melanogaster) ) INOH
FOXO4 pathway0001461 Negative regulation of gene expression ( Insulin receptor signaling (Mammal) ) INOH
FOXO4 pathway0001655 PI3 kinase pathway PANTHER
FOXO4 pathway0001799 RANKL NetPath
FOXO4 pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
FOXO4 pathway0002035 Signaling events mediated by HDAC Class III PID
FOXO4 pathway0002222 TGF_beta_Receptor NetPath
FOXO4 pathway0002732 Hs_Simplified_Interaction_Map_Between_LOXL4_and_Oxidative_Stress_Pathway_WP3670_90107 WikiPathways
FOXO4 pathway0002743 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways
FOXO4 pathway0002862 Hs_AGE-RAGE_pathway_WP2324_89798 WikiPathways
FOXO4 pathway0002866 Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 WikiPathways
FOXP2 pathway0002757 Hs_Pathways_Affected_in_Adenoid_Cystic_Carcinoma_WP3651_89271 WikiPathways
HES5 pathway0000390 CDC42 signaling events PID
HES5 pathway0000483 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Reactome
HES5 pathway0000484 Constitutive Signaling by NOTCH1 PEST Domain Mutants Reactome
HES5 pathway0001517 Notch NetPath
HES5 pathway0001524 NOTCH1 Intracellular Domain Regulates Transcription Reactome
HES5 pathway0001526 NOTCH2 intracellular domain regulates transcription Reactome
HES5 pathway0002589 Notch signaling pathway KEGG
HES7 pathway0002825 Hs_Gene_regulatory_network_modelling_somitogenesis_WP2854_87527 WikiPathways
HES7 pathway0002826 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 WikiPathways
HLX pathway0001116 IL12-mediated signaling events PID
HLX pathway0002688 Hs_TYROBP_Causal_Network_WP3945_90843 WikiPathways
HNF1A pathway0000825 FOXA2 and FOXA3 transcription factor networks PID
HNF1A pathway0001132 IL6 NetPath
HNF1A pathway0001714 Presenilin action in Notch and Wnt signaling PID
HNF1A pathway0001834 Regulation of gene expression in beta cells Reactome
HNF1A pathway0002631 Maturity onset diabetes of the young KEGG
HOXA10 pathway0002035 Signaling events mediated by HDAC Class III PID
HOXC11 pathway0002740 Hs_Endoderm_Differentiation_WP2853_88152 WikiPathways
MECP2 pathway0002728 Hs_MECP2_and_Associated_Rett_Syndrome_WP3584_91190 WikiPathways
MEF2C pathway0000393 CDO in myogenesis Reactome
MEF2C pathway0000430 Circadian Clock Reactome
MEF2C pathway0000692 ErbB1 downstream signaling PID
MEF2C pathway0000715 ERK/MAPK targets Reactome
MEF2C pathway0001517 Notch NetPath
MEF2C pathway0001560 Oxidative stress response PANTHER
MEF2C pathway0001572 p38 MAPK pathway PANTHER
MEF2C pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
MEF2C pathway0001857 Regulation of retinoblastoma protein PID
MEF2C pathway0002034 Signaling events mediated by HDAC Class II PID
MEF2C pathway0002044 Signaling mediated by p38-alpha and p38-beta PID
MEF2C pathway0002222 TGF_beta_Receptor NetPath
MEF2C pathway0002299 Transcriptional activation of mitochondrial biogenesis Reactome
MEF2C pathway0002340 Trk receptor signaling mediated by the MAPK pathway PID
MEF2C pathway0002562 MAPK signaling pathway KEGG
MEF2C pathway0002725 Hs_Endochondral_Ossification_WP474_87977 WikiPathways
MEF2C pathway0002743 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways
MEF2C pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
MEF2C pathway0002799 Hs_Oxidation_by_Cytochrome_P450_WP43_84102 WikiPathways
MEF2C pathway0002853 Hs_TGF-beta_Signaling_Pathway_WP366_90028 WikiPathways
MTF1 pathway0000069 Activation of gene expression by SREBF (SREBP) Reactome
MTF1 pathway0001704 PPARA activates gene expression Reactome
MYB pathway0000187 AP-1 transcription factor network PID
MYB pathway0000335 C-MYB transcription factor network PID
MYB pathway0000747 Factors involved in megakaryocyte development and platelet production Reactome
MYB pathway0001121 IL2 signaling events mediated by PI3K PID
MYB pathway0001127 IL4-mediated signaling events PID
MYB pathway0001516 Notch-mediated HES/HEY network PID
MYB pathway0001727 Prolactin NetPath
MYB pathway0002747 Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways
NEUROD1 pathway0001834 Regulation of gene expression in beta cells Reactome
NEUROD1 pathway0001836 Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells Reactome
NEUROD1 pathway0002631 Maturity onset diabetes of the young KEGG
NEUROD1 pathway0002746 Hs_Dopaminergic_Neurogenesis_WP2855_87239 WikiPathways
NFATC1 pathway0000187 AP-1 transcription factor network PID
NFATC1 pathway0000271 BCR signaling pathway PID
NFATC1 pathway0000340 Ca2+ pathway Reactome
NFATC1 pathway0000343 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID
NFATC1 pathway0000347 Calcium signaling in the CD4+ TCR pathway PID
NFATC1 pathway0000450 CLEC7A (Dectin-1) induces NFAT activation Reactome
NFATC1 pathway0000634 Downstream signaling in naïve CD8+ T cells PID
NFATC1 pathway0000770 FCERI mediated Ca+2 mobilization Reactome
NFATC1 pathway0000916 Glucocorticoid receptor regulatory network PID
NFATC1 pathway0001147 Inflammation mediated by chemokine and cytokine signaling pathway PANTHER
NFATC1 pathway0001799 RANKL NetPath
NFATC1 pathway0001935 Role of Calcineurin-dependent NFAT signaling in lymphocytes PID
NFATC1 pathway0002031 Signaling by Wnt Reactome
NFATC1 pathway0002199 TCR NetPath
NFATC1 pathway0002392 Validated transcriptional targets of AP1 family members Fra1 and Fra2 PID
NFATC1 pathway0002449 Wnt signaling pathway PANTHER
NFATC1 pathway0002587 Wnt signaling pathway KEGG
NFATC1 pathway0002592 Axon guidance KEGG
NFATC1 pathway0002593 VEGF signaling pathway KEGG
NFATC1 pathway0002607 Natural killer cell mediated cytotoxicity KEGG
NFATC1 pathway0002608 T cell receptor signaling pathway KEGG
NFATC1 pathway0002609 B cell receptor signaling pathway KEGG
NFATC1 pathway0002743 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways
NFATC1 pathway0002845 Hs_TLR4_Signaling_and_Tolerance_WP3851_90114 WikiPathways
NFATC1 pathway0002868 Hs_T-Cell_antigen_Receptor_(TCR)_Signaling_Pathway_WP69_89937 WikiPathways
NFATC1 pathway0002874 Hs_RANKL-RANK_(Receptor_activator_of_NFKB_(ligand))_Signaling_Pathway_WP2018_90016 WikiPathways
NKX3-1 pathway0000492 Coregulation of Androgen receptor activity PID
NKX3-1 pathway0000824 FOXA1 transcription factor network PID
NKX3-1 pathway0002656 Pathways in cancer KEGG
NKX3-1 pathway0002662 Prostate cancer KEGG
NKX6-1 pathway0001834 Regulation of gene expression in beta cells Reactome
NKX6-1 pathway0001835 Regulation of gene expression in early pancreatic precursor cells Reactome
NKX6-1 pathway0002631 Maturity onset diabetes of the young KEGG
NR2F6 pathway0001534 Nuclear Receptor transcription pathway Reactome
PITX2 pathway0001848 Regulation of nuclear beta catenin signaling and target gene transcription PID
PITX2 pathway0002591 TGF-beta signaling pathway KEGG
PITX2 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
PITX2 pathway0002771 Hs_BMP_Signaling_Pathway_in_Eyelid_Development_WP3927_90735 WikiPathways
POLR3A pathway0000532 Cytosolic sensors of pathogen-associated DNA Reactome
POLR3A pathway0001926 RNA Polymerase III Abortive And Retractive Initiation Reactome
POLR3A pathway0001927 RNA Polymerase III Chain Elongation Reactome
POLR3A pathway0001928 RNA Polymerase III Transcription Initiation From Type 1 Promoter Reactome
POLR3A pathway0001929 RNA Polymerase III Transcription Initiation From Type 2 Promoter Reactome
POLR3A pathway0001930 RNA Polymerase III Transcription Initiation From Type 3 Promoter Reactome
POLR3A pathway0001931 RNA Polymerase III Transcription Termination Reactome
POLR3A pathway0002492 Purine metabolism KEGG
POLR3A pathway0002494 Pyrimidine metabolism KEGG
POLR3A pathway0002605 Cytosolic DNA-sensing pathway KEGG
POU1F1 pathway0000916 Glucocorticoid receptor regulatory network PID
POU2F1 pathway0000176 AndrogenReceptor NetPath
POU2F1 pathway0000229 ATF-2 transcription factor network PID
POU2F1 pathway0000343 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID
POU2F1 pathway0000347 Calcium signaling in the CD4+ TCR pathway PID
POU2F1 pathway0000824 FOXA1 transcription factor network PID
POU2F1 pathway0000916 Glucocorticoid receptor regulatory network PID
POU2F1 pathway0001825 Regulation of Androgen receptor activity PID
POU2F1 pathway0001921 RNA polymerase II transcribes snRNA genes Reactome
POU2F1 pathway0001926 RNA Polymerase III Abortive And Retractive Initiation Reactome
POU2F1 pathway0001930 RNA Polymerase III Transcription Initiation From Type 3 Promoter Reactome
POU2F1 pathway0002751 Hs_Integrated_Cancer_Pathway_WP1971_82939 WikiPathways
RARG pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
RARG pathway0001534 Nuclear Receptor transcription pathway Reactome
RARG pathway0001883 Retinoic acid receptors-mediated signaling PID
RARG pathway0001947 RXR and RAR heterodimerization with other nuclear receptor PID
RARG pathway0002028 Signaling by Retinoic Acid Reactome
SOX9 pathway0000549 Deactivation of the beta-catenin transactivating complex Reactome
SOX9 pathway0002222 TGF_beta_Receptor NetPath
SOX9 pathway0002747 Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways
SOX9 pathway0002791 Hs_Spinal_Cord_Injury_WP2431_87678 WikiPathways
SP1 pathway0000069 Activation of gene expression by SREBF (SREBP) Reactome
SP1 pathway0000176 AndrogenReceptor NetPath
SP1 pathway0000187 AP-1 transcription factor network PID
SP1 pathway0000335 C-MYB transcription factor network PID
SP1 pathway0000608 Direct p53 effectors PID
SP1 pathway0000648 E2F transcription factor network PID
SP1 pathway0000658 EGFR1 NetPath
SP1 pathway0000824 FOXA1 transcription factor network PID
SP1 pathway0000825 FOXA2 and FOXA3 transcription factor networks PID
SP1 pathway0000826 FOXM1 transcription factor network PID
SP1 pathway0001021 HIF-1-alpha transcription factor network PID
SP1 pathway0001022 HIF-2-alpha transcription factor network PID
SP1 pathway0001046 Huntington disease PANTHER
SP1 pathway0001122 IL2 signaling events mediated by STAT5 PID
SP1 pathway0001127 IL4-mediated signaling events PID
SP1 pathway0001264 Leptin NetPath
SP1 pathway0001543 Oncogene Induced Senescence Reactome
SP1 pathway0001582 p73 transcription factor network PID
SP1 pathway0001704 PPARA activates gene expression Reactome
SP1 pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
SP1 pathway0001861 Regulation of Telomerase PID
SP1 pathway0001921 RNA polymerase II transcribes snRNA genes Reactome
SP1 pathway0002069 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome
SP1 pathway0002222 TGF_beta_Receptor NetPath
SP1 pathway0002391 Validated targets of C-MYC transcriptional repression PID
SP1 pathway0002392 Validated transcriptional targets of AP1 family members Fra1 and Fra2 PID
SP1 pathway0002394 Validated transcriptional targets of TAp63 isoforms PID
SP1 pathway0002591 TGF-beta signaling pathway KEGG
SP1 pathway0002642 Huntington's disease KEGG
SP1 pathway0002699 Hs_Corticotropin-releasing_hormone_signaling_pathway_WP2355_90017 WikiPathways
SP1 pathway0002712 Hs_Leptin_signaling_pathway_WP2034_89856 WikiPathways
SP1 pathway0002718 Hs_Interleukin-11_Signaling_Pathway_WP2332_79525 WikiPathways
SP1 pathway0002731 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 WikiPathways
SP1 pathway0002811 Hs_Estrogen_signaling_pathway_WP712_78491 WikiPathways
SP1 pathway0002812 Hs_Sudden_Infant_Death_Syndrome_(SIDS)_Susceptibility_Pathways_WP706_86078 WikiPathways
SP1 pathway0002853 Hs_TGF-beta_Signaling_Pathway_WP366_90028 WikiPathways
SP1 pathway0002862 Hs_AGE-RAGE_pathway_WP2324_89798 WikiPathways
SP1 pathway0002863 Hs_Androgen_receptor_signaling_pathway_WP138_79958 WikiPathways
SP1 pathway0002866 Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 WikiPathways
SRF pathway0000492 Coregulation of Androgen receptor activity PID
SRF pathway0000692 ErbB1 downstream signaling PID
SRF pathway0001191 Interleukin signaling pathway PANTHER
SRF pathway0001572 p38 MAPK pathway PANTHER
SRF pathway0001574 p38 signaling mediated by MAPKAP kinases PID
SRF pathway0001604 PDGF signaling pathway PANTHER
SRF pathway0001605 PDGFR-alpha signaling pathway PID
SRF pathway0001606 PDGFR-beta signaling pathway PID
SRF pathway0001805 Ras Pathway PANTHER
SRF pathway0001894 RHO GTPases Activate Formins Reactome
SRF pathway0001903 RhoA signaling pathway PID
SRF pathway0002034 Signaling events mediated by HDAC Class II PID
SRF pathway0002340 Trk receptor signaling mediated by the MAPK pathway PID
SRF pathway0002562 MAPK signaling pathway KEGG
SRF pathway0002743 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways
SRF pathway0002750 Hs_Serotonin_Receptor_4-6-7_and_NR3C_Signaling_WP734_74438 WikiPathways
SRF pathway0002826 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 WikiPathways
SRF pathway0002834 Hs_Serotonin_Receptor_2_and_ELK-SRF-GATA4_signaling_WP732_80010 WikiPathways
TFAP2A pathway0000377 Caspase Cascade in Apoptosis PID
TFAP2A pathway0002699 Hs_Corticotropin-releasing_hormone_signaling_pathway_WP2355_90017 WikiPathways
TFAP2A pathway0002747 Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways
TFAP2A pathway0002841 Hs_Ectoderm_Differentiation_WP2858_89329 WikiPathways
TFAP2A pathway0002849 Hs_Hypothetical_Craniofacial_Development_Pathway_WP3655_88473 WikiPathways
TTF1 pathway0000078 Activation of rRNA Expression by ERCC6 (CSB) and EHMT2 (G9a) Reactome
TTF1 pathway0000902 General transcription by RNA polymerase I PANTHER
TTF1 pathway0001512 NoRC negatively regulates rRNA expression Reactome
TTF1 pathway0001916 RNA Polymerase I Transcription Initiation Reactome
TTF1 pathway0001917 RNA Polymerase I Transcription Termination Reactome
TTF1 pathway0002140 Surfactant metabolism Reactome
YY1 pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
YY1 pathway0000616 DNA Damage Recognition in GG-NER Reactome
YY1 pathway0000648 E2F transcription factor network PID
YY1 pathway0001400 mTOR signaling pathway PID
YY1 pathway0001516 Notch-mediated HES/HEY network PID
YY1 pathway0001517 Notch NetPath
YY1 pathway0001523 Notch signaling pathway PID
YY1 pathway0001579 p53 pathway PID
YY1 pathway0002033 Signaling events mediated by HDAC Class I PID