General Details

Super-enhancer:SE_00_02600393
Genomic Locus: chr12: 50056005-50069690
Size/Length:13685bp
Conservation:0.137208
BioSample Type:Tissue
Tissue Type:Muscle of trunk
Sample Name:muscle-of-trunk
Source:Roadmap
Element:2
Rank:393
ChIP Density(Case):16801.0745
ChIP Density(Input):1367.1315

Super-enhancer Associated Network


* The complex regulatory networks formed by this SE , SE associated genes , TFs binding to the SE and their upstream pathways can be interactively visualized.


Fimo:
SE-Gene Linking Strategies:
Pathway Enriciment Threshold:
Top Pathway:
 



Super-enhancer Associated Statistics

Associated Gene Details

ROSE Overlap:FMNL3
ROSE Proximal:PRPF40B
ROSE Closest:FMNL3
The Closest Active:FMNL3

Factors Binding to Super-enhancer




Using these SE element regions to analyze by online tools GREAT *The TFs binding to this SE identified by ChIP-seq.

Chrome Element_Start Element_End TF TF Source TF_Start TF_End TF Class Master TF

Using these SE element regions to analyze by online tools GREAT * The TFs binding to this SE predicted by Motif.

Chrome Element_Start Element_End TF Database TF_Start TF_End Score P_Value TF Class Master TF
chr12 50064651 50069690 ASCC1 Transfac.V$P50_Q6 50065244 50065255 15.71430 2.54e-07 TcoF-DB_TcoF N
chr12 50064651 50069690 ASCC1 Transfac.V$P50_Q6 50065246 50065257 15.94810 6.49e-08 TcoF-DB_TcoF N
chr12 50064651 50069690 DMRTA1 Transfac.V$DMRT4_01 50065483 50065495 16.71110 7.3e-07 Zinc-coordinating DNA-binding domains N
chr12 50056005 50059618 ELF3 Transfac.V$ELF4_04 50057722 50057738 14.89940 2.18e-07 Helix-turn-helix domains N
chr12 50056005 50059618 ELF3 Uniprobe.UP00407_2 50057722 50057738 14.79890 2.37e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXC1 Transfac.V$FOXC1_02 50058016 50058028 18.36360 3.25e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXC1 Transfac.V$FOXC1_02 50058020 50058032 19.69090 9.54e-08 Helix-turn-helix domains N
chr12 50056005 50059618 FOXC1 Transfac.V$FOXC1_02 50058190 50058202 17.98180 4.39e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXC1 Transfac.V$FOXC1_02 50058194 50058206 17.87270 4.86e-07 Helix-turn-helix domains N
chr12 50064651 50069690 FOXC1 Transfac.V$FOXC1_02 50067610 50067622 17.54550 6.45e-07 Helix-turn-helix domains N
chr12 50064651 50069690 FOXC1 Transfac.V$FOXC1_05 50067610 50067620 18.20690 8.16e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXC1 Jolma2013.FOXC1_DBD 50058016 50058028 18.32320 3.25e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXC1 Jolma2013.FOXC1_DBD 50058020 50058032 19.64650 9.54e-08 Helix-turn-helix domains N
chr12 50056005 50059618 FOXC1 Jolma2013.FOXC1_DBD 50058190 50058202 17.95960 4.26e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXC1 Jolma2013.FOXC1_DBD 50058194 50058206 17.83840 4.86e-07 Helix-turn-helix domains N
chr12 50064651 50069690 FOXC1 Jolma2013.FOXC1_DBD 50067610 50067622 17.50510 6.45e-07 Helix-turn-helix domains N
chr12 50064651 50069690 FOXC1 Jolma2013.Foxc1_DBD 50067610 50067620 18.15150 8.16e-07 Helix-turn-helix domains N
chr12 50064651 50069690 FOXC2 Transfac.V$FOXC2_02 50067610 50067620 17.51520 8.16e-07 Helix-turn-helix domains N
chr12 50064651 50069690 FOXC2 Jolma2013.FOXC2_DBD_2 50067610 50067620 17.47750 8.16e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXJ2 Transfac.V$FOXJ2_01 50058016 50058033 18.72220 3.35e-08 Helix-turn-helix domains N
chr12 50056005 50059618 FOXJ2 Transfac.V$FOXJ2_01 50058020 50058037 17.43330 3.23e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXJ2 Transfac.V$FOXJ2_01 50058186 50058203 17.83330 1.74e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXJ2 Transfac.V$FOXJ2_01 50058190 50058207 16.61110 9.56e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXL1 Transfac.V$FOXL1_04 50058013 50058029 17.28920 8.72e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXL1 Transfac.V$FOXL1_06 50058017 50058029 17.84210 2.69e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXL1 Transfac.V$FOXL1_06 50058021 50058033 17.14470 5.91e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXL1 Jolma2013.FOXL1_full_2 50058017 50058029 17.77780 2.69e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXL1 Jolma2013.FOXL1_full_2 50058021 50058033 17.08080 5.91e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXL1 Uniprobe.UP00061_1 50058013 50058029 17.32320 8.5e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXP1 Transfac.V$FOXP1_01 50058190 50058209 4.12048 6.2e-07 Helix-turn-helix domains N
chr12 50056005 50059618 FOXP1 JASPAR2014.MA0481.1 50058191 50058205 17.21130 6.62e-07 Helix-turn-helix domains N
chr12 50064651 50069690 GFI1 Transfac.V$GFI1_Q6_01 50068058 50068067 13.43370 9.1e-07 Zinc-coordinating DNA-binding domains N
chr12 50064651 50069690 HOXA5 Transfac.V$HOX13_01 50068261 50068290 17.44550 6.85e-07 Helix-turn-helix domains Y
chr12 50064651 50069690 INSM1 Transfac.V$INSM1_01 50066396 50066407 17.22000 6.58e-07 Zinc-coordinating DNA-binding domains N
chr12 50064651 50069690 INSM1 JASPAR2014.MA0155.1 50066396 50066407 17.22000 6.58e-07 Zinc-coordinating DNA-binding domains N
chr12 50064651 50069690 IRF1 JASPAR2014.MA0050.2 50066169 50066189 17.37100 8.05e-07 Helix-turn-helix domains N
chr12 50064651 50069690 IRF9 Transfac.V$ISGF4G_04 50066838 50066851 13.11430 2.99e-07 Helix-turn-helix domains N
chr12 50064651 50069690 IRF9 Uniprobe.UP00074_2 50066838 50066851 13.16000 2.85e-07 Helix-turn-helix domains N
chr12 50056005 50059618 JUN JASPAR2014.MA0488.1 50058656 50058668 17.38780 7.91e-07 Basic domains N
chr12 50064651 50069690 MAF Transfac.V$MAF_Q6 50064893 50064908 19.25000 3.51e-07 Basic domains N
chr12 50056005 50059618 MTF1 Transfac.V$MTF1_Q4 50056205 50056218 19.28180 1.53e-07 Zinc-coordinating DNA-binding domains N
chr12 50056005 50059618 MTF1 Uniprobe.UP00097_1 50056205 50056220 16.90990 9.89e-07 Zinc-coordinating DNA-binding domains N
chr12 50064651 50069690 MYEF2 Transfac.V$HMEF2_Q6 50067466 50067481 16.04550 5.98e-07 alpha-Helices exposed by beta-structures N
chr12 50064651 50069690 MYEF2 Transfac.V$MEF2_01 50067466 50067481 17.46770 2.56e-07 alpha-Helices exposed by beta-structures N
chr12 50064651 50069690 NFKB1 Transfac.V$NFKB_Q6 50065244 50065257 17.27270 4.57e-07 Immunoglobulin fold N
chr12 50064651 50069690 NFKB1 Transfac.V$NFKB_Q6 50065244 50065257 16.85860 8.44e-07 Immunoglobulin fold N
chr12 50064651 50069690 NFKB1 Transfac.V$NFKB_Q6_01 50065241 50065256 16.79520 3.5e-07 Immunoglobulin fold N
chr12 50064651 50069690 NFKB2 Transfac.V$NFKB2_01 50065244 50065256 17.49300 8.98e-07 Immunoglobulin fold N
chr12 50064651 50069690 NFKB2 Transfac.V$NFKB2_01 50065244 50065256 17.67610 7.86e-07 Immunoglobulin fold N
chr12 50064651 50069690 NFKB2 Jolma2013.NFKB2_DBD 50065244 50065256 17.41000 8.98e-07 Immunoglobulin fold N
chr12 50064651 50069690 NFKB2 Jolma2013.NFKB2_DBD 50065244 50065256 17.59000 7.86e-07 Immunoglobulin fold N
chr12 50064651 50069690 NKX2-5 JASPAR2014.MA0503.1 50068168 50068178 15.98180 9.51e-07 Helix-turn-helix domains N
chr12 50056005 50059618 PAX5 JASPAR2014.MA0014.2 50058160 50058178 16.79370 8.21e-07 Helix-turn-helix domains N
chr12 50056005 50059618 PITX2 Transfac.V$PITX2_Q2 50057772 50057782 16.09090 8.91e-07 Helix-turn-helix domains N
chr12 50056005 50059618 PITX2 Transfac.V$PITX2_Q6 50057772 50057781 15.07070 9.1e-07 Helix-turn-helix domains N
chr12 50056005 50059618 POLR3A Transfac.V$RPC155_01 50057684 50057699 18.31200 3.4e-07 ENCODE_TF N
chr12 50056005 50059618 POLR3A Transfac.V$RPC155_01 50057819 50057834 17.32800 7.47e-07 ENCODE_TF N
chr12 50064651 50069690 REL Transfac.V$CREL_Q6 50065245 50065256 15.60000 6.16e-07 TcoF-DB_TF N
chr12 50064651 50069690 REL Transfac.V$CREL_Q6 50065245 50065256 15.60000 6.16e-07 TcoF-DB_TF N
chr12 50056005 50059618 SOX4 Uniprobe.UP00062_1 50057398 50057414 16.66360 3.82e-07 Other all-alpha-helical DNA-binding domains N
chr12 50064651 50069690 SOX9 Transfac.V$SOX9_B1 50069611 50069624 15.33730 9.09e-07 Other all-alpha-helical DNA-binding domains N
chr12 50056005 50059618 SOX9 Transfac.V$SOX9_Q4 50057402 50057412 14.08180 9.01e-07 Other all-alpha-helical DNA-binding domains N
chr12 50056005 50059618 SOX9 Transfac.V$SOX9_Q4 50058389 50058399 14.10910 6.68e-07 Other all-alpha-helical DNA-binding domains N
chr12 50056005 50059618 SRF Transfac.V$SRF_06 50057722 50057738 17.07950 1.16e-09 alpha-Helices exposed by beta-structures N
chr12 50056005 50059618 SRF Transfac.V$SRF_06 50057723 50057739 14.27270 5.72e-07 alpha-Helices exposed by beta-structures N
chr12 50056005 50059618 SRF Transfac.V$SRF_06 50059007 50059023 14.09090 7.47e-07 alpha-Helices exposed by beta-structures N
chr12 50056005 50059618 SRF Transfac.V$SRF_06 50059010 50059026 13.92050 9.58e-07 alpha-Helices exposed by beta-structures N
chr12 50056005 50059618 SRF Uniprobe.UP00077_2 50057722 50057738 17.06780 1.03e-09 alpha-Helices exposed by beta-structures N
chr12 50056005 50059618 SRF Uniprobe.UP00077_2 50057723 50057739 14.20900 5.76e-07 alpha-Helices exposed by beta-structures N
chr12 50056005 50059618 SRF Uniprobe.UP00077_2 50059007 50059023 14.02820 7.54e-07 alpha-Helices exposed by beta-structures N
chr12 50056005 50059618 SRF Uniprobe.UP00077_2 50059010 50059026 13.88140 9.32e-07 alpha-Helices exposed by beta-structures N
chr12 50064651 50069690 TCF3 JASPAR2014.MA0522.1 50064923 50064933 15.91840 5.08e-07 Basic domains N
chr12 50056005 50059618 TFAP2A Transfac.V$TFAP2A_04 50058609 50058621 15.10910 9.61e-07 Basic domains N
chr12 50056005 50059618 TFAP2A Transfac.V$TFAP2A_07 50058609 50058621 16.87270 3.26e-07 Basic domains N
chr12 50056005 50059618 TFAP2A Jolma2013.TFAP2A_DBD_3 50058609 50058621 15.07000 9.26e-07 Basic domains N
chr12 50056005 50059618 TFAP2C Jolma2013.TFAP2C_DBD_3 50058609 50058621 16.94000 8.44e-07 Basic domains N
chr12 50064651 50069690 TFAP4 Transfac.V$AP4_01 50064919 50064936 18.25000 6.11e-07 Basic domains Y
chr12 50064651 50069690 TFAP4 Transfac.V$AP4_01 50067332 50067349 19.75000 1.78e-07 Basic domains Y
chr12 50064651 50069690 TFAP4 Transfac.V$AP4_Q6_02 50067336 50067348 15.10000 3.59e-07 Basic domains Y
chr12 50064651 50069690 ZNF263 JASPAR2014.MA0528.1 50065230 50065250 17.98000 4.02e-07 Zinc-coordinating DNA-binding domains N
chr12 50056005 50059618 ZNF35 Transfac.V$ZFP105_03 50058195 50058209 16.29370 5.36e-08 Zinc-coordinating DNA-binding domains N
chr12 50056005 50059618 ZNF35 Uniprobe.UP00037_1 50058195 50058209 16.27080 5.06e-08 Zinc-coordinating DNA-binding domains N
chr12 50064651 50069690 ZSCAN4 Transfac.V$ZSCAN4_04 50069522 50069537 16.84340 4.1e-07 Zinc-coordinating DNA-binding domains N
chr12 50064651 50069690 ZSCAN4 Uniprobe.UP00026_2 50069522 50069537 16.76580 4.17e-07 Zinc-coordinating DNA-binding domains N

The Upstream Pathways of TFs Binding to SE



TF Pathway ID Pathway Name Source
ELF3 pathway0000658 EGFR1 NetPath
ELF3 pathway0001604 PDGF signaling pathway PANTHER
FOXC1 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
FOXC1 pathway0002826 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 WikiPathways
GFI1 pathway0002391 Validated targets of C-MYC transcriptional repression PID
INSM1 pathway0001836 Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells Reactome
IRF1 pathway0000747 Factors involved in megakaryocyte development and platelet production Reactome
IRF1 pathway0000916 Glucocorticoid receptor regulatory network PID
IRF1 pathway0001079 IFN-gamma pathway PID
IRF1 pathway0001117 IL12 signaling mediated by STAT4 PID
IRF1 pathway0001131 IL6-mediated signaling events PID
IRF1 pathway0001180 Interferon alpha/beta signaling Reactome
IRF1 pathway0001181 Interferon gamma signaling Reactome
IRF1 pathway0001861 Regulation of Telomerase PID
IRF1 pathway0002282 TRAF6 mediated IRF7 activation Reactome
IRF1 pathway0002655 Hepatitis C KEGG
IRF1 pathway0002686 Hs_Tryptophan_metabolism_WP465_85055 WikiPathways
IRF9 pathway0001079 IFN-gamma pathway PID
IRF9 pathway0001080 IFN alpha signaling pathway((JAK1 TYK2 STAT1 STAT2) ( IFN alpha signaling(JAK1 TYK2 STAT1 STAT2 STAT3) ) INOH
IRF9 pathway0001180 Interferon alpha/beta signaling Reactome
IRF9 pathway0001181 Interferon gamma signaling Reactome
IRF9 pathway0002606 Jak-STAT signaling pathway KEGG
IRF9 pathway0002655 Hepatitis C KEGG
IRF9 pathway0002682 Hs_Interferon_type_I_signaling_pathways_WP585_85198 WikiPathways
JUN pathway0000061 Activation of anterior HOX genes in hindbrain development during early embryogenesis Reactome
JUN pathway0000080 Activation of the AP-1 family of transcription factors Reactome
JUN pathway0000147 Alpha6Beta4Integrin NetPath
JUN pathway0000176 AndrogenReceptor NetPath
JUN pathway0000177 Angiogenesis PANTHER
JUN pathway0000187 AP-1 transcription factor network PID
JUN pathway0000196 Apoptosis signaling pathway PANTHER
JUN pathway0000229 ATF-2 transcription factor network PID
JUN pathway0000265 B cell activation PANTHER
JUN pathway0000270 BCR NetPath
JUN pathway0000271 BCR signaling pathway PID
JUN pathway0000343 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID
JUN pathway0000347 Calcium signaling in the CD4+ TCR pathway PID
JUN pathway0000388 CD40/CD40L signaling PID
JUN pathway0000390 CDC42 signaling events PID
JUN pathway0000608 Direct p53 effectors PID
JUN pathway0000634 Downstream signaling in naïve CD8+ T cells PID
JUN pathway0000658 EGFR1 NetPath
JUN pathway0000669 Endothelins PID
JUN pathway0000692 ErbB1 downstream signaling PID
JUN pathway0000695 ErbB2/ErbB3 signaling events PID
JUN pathway0000756 FAS signaling pathway PANTHER
JUN pathway0000767 Fc-epsilon receptor I signaling in mast cells PID
JUN pathway0000771 FCERI mediated MAPK activation Reactome
JUN pathway0000780 FGF signaling pathway PID
JUN pathway0000824 FOXA1 transcription factor network PID
JUN pathway0000895 Gene expression of IL2 by AP-1 ( CD4 T cell receptor signaling (JNK cascade) ) INOH
JUN pathway0000896 Gene expression of IL2 by AP-1 ( CD4 T cell receptor signaling ) INOH
JUN pathway0000916 Glucocorticoid receptor regulatory network PID
JUN pathway0001021 HIF-1-alpha transcription factor network PID
JUN pathway0001046 Huntington disease PANTHER
JUN pathway0001114 IL1-mediated signaling events PID
JUN pathway0001115 IL1 NetPath
JUN pathway0001117 IL12 signaling mediated by STAT4 PID
JUN pathway0001119 IL2-mediated signaling events PID
JUN pathway0001120 IL2 NetPath
JUN pathway0001130 IL5 NetPath
JUN pathway0001131 IL6-mediated signaling events PID
JUN pathway0001132 IL6 NetPath
JUN pathway0001147 Inflammation mediated by chemokine and cytokine signaling pathway PANTHER
JUN pathway0001170 Integrin-linked kinase signaling PID
JUN pathway0001194 Intracellular Signalling Through Adenosine Receptor A2a and Adenosine SMPDB
JUN pathway0001195 Intracellular Signalling Through Adenosine Receptor A2b and Adenosine SMPDB
JUN pathway0001230 JNK cascade ( CD4 T cell receptor signaling (JNK cascade) ) INOH
JUN pathway0001231 JNK cascade ( CD4 T cell receptor signaling ) INOH
JUN pathway0001232 JNK cascade ( TGF-beta signaling(through TAK1) ) INOH
JUN pathway0001233 JNK cascade ( Toll-like receptor signaling pathway (through ECSIT, MEKK1, MKKs, JNK cascade) ) INOH
JUN pathway0001234 JNK signaling in the CD4+ TCR pathway PID
JUN pathway0001246 KitReceptor NetPath
JUN pathway0001295 LPA receptor mediated events PID
JUN pathway0001322 MAPK6/MAPK4 signaling Reactome
JUN pathway0001473 Nephrin/Neph1 signaling in the kidney podocyte PID
JUN pathway0001554 Osteopontin-mediated events PID
JUN pathway0001559 Oxidative Stress Induced Senescence Reactome
JUN pathway0001560 Oxidative stress response PANTHER
JUN pathway0001604 PDGF signaling pathway PANTHER
JUN pathway0001605 PDGFR-alpha signaling pathway PID
JUN pathway0001606 PDGFR-beta signaling pathway PID
JUN pathway0001711 Pre-NOTCH Transcription and Translation Reactome
JUN pathway0001714 Presenilin action in Notch and Wnt signaling PID
JUN pathway0001727 Prolactin NetPath
JUN pathway0001788 RAC1 signaling pathway PID
JUN pathway0001799 RANKL NetPath
JUN pathway0001805 Ras Pathway PANTHER
JUN pathway0001825 Regulation of Androgen receptor activity PID
JUN pathway0001848 Regulation of nuclear beta catenin signaling and target gene transcription PID
JUN pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
JUN pathway0001857 Regulation of retinoblastoma protein PID
JUN pathway0001861 Regulation of Telomerase PID
JUN pathway0001903 RhoA signaling pathway PID
JUN pathway0001950 S1P2 pathway PID
JUN pathway0001980 Senescence-Associated Secretory Phenotype (SASP) Reactome
JUN pathway0002032 Signaling events mediated by focal adhesion kinase PID
JUN pathway0002036 Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) PID
JUN pathway0002043 Signaling events regulated by Ret tyrosine kinase PID
JUN pathway0002044 Signaling mediated by p38-alpha and p38-beta PID
JUN pathway0002183 T cell activation PANTHER
JUN pathway0002199 TCR NetPath
JUN pathway0002217 TGF-beta signaling pathway PANTHER
JUN pathway0002222 TGF_beta_Receptor NetPath
JUN pathway0002249 TNFalpha NetPath
JUN pathway0002264 Toll receptor signaling pathway PANTHER
JUN pathway0002273 TP53 Regulates Transcription of DNA Repair Genes Reactome
JUN pathway0002388 Validated nuclear estrogen receptor alpha network PID
JUN pathway0002392 Validated transcriptional targets of AP1 family members Fra1 and Fra2 PID
JUN pathway0002439 Wnt NetPath
JUN pathway0002469 JNK cascade ( IL-1 signaling pathway (through JNK cascade) ) INOH
JUN pathway0002471 JNK cascade ( Toll-like receptor signaling pathway (through JNK cascade) ) INOH
JUN pathway0002562 MAPK signaling pathway KEGG
JUN pathway0002564 ErbB signaling pathway KEGG
JUN pathway0002587 Wnt signaling pathway KEGG
JUN pathway0002594 Focal adhesion KEGG
JUN pathway0002602 Toll-like receptor signaling pathway KEGG
JUN pathway0002608 T cell receptor signaling pathway KEGG
JUN pathway0002609 B cell receptor signaling pathway KEGG
JUN pathway0002617 Neurotrophin signaling pathway KEGG
JUN pathway0002625 GnRH signaling pathway KEGG
JUN pathway0002646 Epithelial cell signaling in Helicobacter pylori infection KEGG
JUN pathway0002649 Leishmaniasis KEGG
JUN pathway0002650 Chagas disease KEGG
JUN pathway0002656 Pathways in cancer KEGG
JUN pathway0002657 Colorectal cancer KEGG
JUN pathway0002658 Renal cell carcinoma KEGG
JUN pathway0002709 Hs_MAPK_Signaling_Pathway_WP382_79951 WikiPathways
JUN pathway0002717 Hs_Hepatitis_C_and_Hepatocellular_Carcinoma_WP3646_88640 WikiPathways
JUN pathway0002719 Hs_Apoptosis_WP254_88977 WikiPathways
JUN pathway0002731 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 WikiPathways
JUN pathway0002733 Hs_T-Cell_antigen_Receptor_(TCR)_pathway_during_Staphylococcus_aureus_infection_WP3863_90702 WikiPathways
JUN pathway0002734 Hs_Apoptosis_Modulation_and_Signaling_WP1772_91293 WikiPathways
JUN pathway0002735 Hs_PDGF_Pathway_WP2526_82681 WikiPathways
JUN pathway0002743 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways
JUN pathway0002752 Hs_ATM_Signaling_Pathway_WP2516_90247 WikiPathways
JUN pathway0002771 Hs_BMP_Signaling_Pathway_in_Eyelid_Development_WP3927_90735 WikiPathways
JUN pathway0002788 Hs_Nucleotide_Metabolism_WP404_68960 WikiPathways
JUN pathway0002801 Hs_TNF_alpha_Signaling_Pathway_WP231_89895 WikiPathways
JUN pathway0002811 Hs_Estrogen_signaling_pathway_WP712_78491 WikiPathways
JUN pathway0002837 Hs_IL-5_Signaling_Pathway_WP127_78498 WikiPathways
JUN pathway0002853 Hs_TGF-beta_Signaling_Pathway_WP366_90028 WikiPathways
JUN pathway0002865 Hs_Brain-Derived_Neurotrophic_Factor_(BDNF)_signaling_pathway_WP2380_89803 WikiPathways
JUN pathway0002866 Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 WikiPathways
JUN pathway0002868 Hs_T-Cell_antigen_Receptor_(TCR)_Signaling_Pathway_WP69_89937 WikiPathways
JUN pathway0002870 Hs_IL-1_signaling_pathway_WP195_89932 WikiPathways
JUN pathway0002871 Hs_IL-3_Signaling_Pathway_WP286_78583 WikiPathways
JUN pathway0002877 Hs_B_Cell_Receptor_Signaling_Pathway_WP23_89900 WikiPathways
MAF pathway0000187 AP-1 transcription factor network PID
MAF pathway0000335 C-MYB transcription factor network PID
MAF pathway0000343 Calcineurin-regulated NFAT-dependent transcription in lymphocytes PID
MAF pathway0002688 Hs_TYROBP_Causal_Network_WP3945_90843 WikiPathways
MTF1 pathway0000069 Activation of gene expression by SREBF (SREBP) Reactome
MTF1 pathway0001704 PPARA activates gene expression Reactome
NFKB1 pathway0000072 Activation of NF-kappaB in B cells Reactome
NFKB1 pathway0000151 Alternative NF-kappaB pathway PID
NFKB1 pathway0000155 amb2 Integrin signaling PID
NFKB1 pathway0000178 Angiopoietin receptor Tie2-mediated signaling PID
NFKB1 pathway0000196 Apoptosis signaling pathway PANTHER
NFKB1 pathway0000250 Atypical NF-kappaB pathway PID
NFKB1 pathway0000270 BCR NetPath
NFKB1 pathway0000271 BCR signaling pathway PID
NFKB1 pathway0000353 Canonical NF-kappaB pathway PID
NFKB1 pathway0000380 CD209 (DC-SIGN) signaling Reactome
NFKB1 pathway0000388 CD40/CD40L signaling PID
NFKB1 pathway0000403 Ceramide signaling pathway PID
NFKB1 pathway0000451 CLEC7A (Dectin-1) signaling Reactome
NFKB1 pathway0000452 CLEC7A/inflammasome pathway Reactome
NFKB1 pathway0000590 DEx/H-box helicases activate type I IFN and inflammatory cytokines production Reactome
NFKB1 pathway0000636 Downstream TCR signaling Reactome
NFKB1 pathway0000658 EGFR1 NetPath
NFKB1 pathway0000687 EPO signaling pathway PID
NFKB1 pathway0000767 Fc-epsilon receptor I signaling in mast cells PID
NFKB1 pathway0000772 FCERI mediated NF-kB activation Reactome
NFKB1 pathway0000916 Glucocorticoid receptor regulatory network PID
NFKB1 pathway0001033 HIV-1 Nef: Negative effector of Fas and TNF-alpha PID
NFKB1 pathway0001089 IkBA variant leads to EDA-ID Reactome
NFKB1 pathway0001090 IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) Reactome
NFKB1 pathway0001091 IKK-NF-kappaB cascade ( B cell receptor signaling ) INOH
NFKB1 pathway0001092 IKK-NF-kappaB cascade ( CD4 T cell receptor signaling (NF-kB cascade) ) INOH
NFKB1 pathway0001093 IKK-NF-kappaB cascade ( CD4 T cell receptor signaling ) INOH
NFKB1 pathway0001094 IKK-NFkB cascade ( TNFR1 signaling pathway ) INOH
NFKB1 pathway0001114 IL1-mediated signaling events PID
NFKB1 pathway0001115 IL1 NetPath
NFKB1 pathway0001116 IL12-mediated signaling events PID
NFKB1 pathway0001120 IL2 NetPath
NFKB1 pathway0001121 IL2 signaling events mediated by PI3K PID
NFKB1 pathway0001123 IL23-mediated signaling events PID
NFKB1 pathway0001126 IL3 NetPath
NFKB1 pathway0001128 IL4 NetPath
NFKB1 pathway0001130 IL5 NetPath
NFKB1 pathway0001132 IL6 NetPath
NFKB1 pathway0001182 Interleukin-1 processing Reactome
NFKB1 pathway0001194 Intracellular Signalling Through Adenosine Receptor A2a and Adenosine SMPDB
NFKB1 pathway0001195 Intracellular Signalling Through Adenosine Receptor A2b and Adenosine SMPDB
NFKB1 pathway0001264 Leptin NetPath
NFKB1 pathway0001295 LPA receptor mediated events PID
NFKB1 pathway0001319 MAP3K8 (TPL2)-dependent MAPK1/3 activation Reactome
NFKB1 pathway0001482 NF-kB is activated and signals survival Reactome
NFKB1 pathway0001483 NF-kB signaling ( Toll-like receptor signaling pathway (trough NF-kappaB) ) INOH
NFKB1 pathway0001517 Notch NetPath
NFKB1 pathway0001554 Osteopontin-mediated events PID
NFKB1 pathway0001727 Prolactin NetPath
NFKB1 pathway0001799 RANKL NetPath
NFKB1 pathway0001821 Regulated proteolysis of p75NTR Reactome
NFKB1 pathway0001861 Regulation of Telomerase PID
NFKB1 pathway0001908 RIP-mediated NFkB activation via ZBP1 Reactome
NFKB1 pathway0001980 Senescence-Associated Secretory Phenotype (SASP) Reactome
NFKB1 pathway0002033 Signaling events mediated by HDAC Class I PID
NFKB1 pathway0002185 T cell receptor signaling (PLC gamma, PKC, Ras and IKK-NF-kappaB cascade) ( CD4 T cell receptor signaling (NF-kB cascade) ) INOH
NFKB1 pathway0002186 T cell receptor signaling pathway ( CD4 T cell receptor signaling ) INOH
NFKB1 pathway0002189 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Reactome
NFKB1 pathway0002199 TCR NetPath
NFKB1 pathway0002222 TGF_beta_Receptor NetPath
NFKB1 pathway0002246 TNF receptor signaling pathway PID
NFKB1 pathway0002249 TNFalpha NetPath
NFKB1 pathway0002284 TRAF6 mediated NF-kB activation Reactome
NFKB1 pathway0002302 Transcriptional regulation of white adipocyte differentiation Reactome
NFKB1 pathway0002355 TSLP NetPath
NFKB1 pathway0002356 TWEAK NetPath
NFKB1 pathway0002562 MAPK signaling pathway KEGG
NFKB1 pathway0002568 Chemokine signaling pathway KEGG
NFKB1 pathway0002584 Apoptosis KEGG
NFKB1 pathway0002602 Toll-like receptor signaling pathway KEGG
NFKB1 pathway0002603 NOD-like receptor signaling pathway KEGG
NFKB1 pathway0002604 RIG-I-like receptor signaling pathway KEGG
NFKB1 pathway0002605 Cytosolic DNA-sensing pathway KEGG
NFKB1 pathway0002608 T cell receptor signaling pathway KEGG
NFKB1 pathway0002609 B cell receptor signaling pathway KEGG
NFKB1 pathway0002617 Neurotrophin signaling pathway KEGG
NFKB1 pathway0002628 Adipocytokine signaling pathway KEGG
NFKB1 pathway0002646 Epithelial cell signaling in Helicobacter pylori infection KEGG
NFKB1 pathway0002648 Shigellosis KEGG
NFKB1 pathway0002649 Leishmaniasis KEGG
NFKB1 pathway0002650 Chagas disease KEGG
NFKB1 pathway0002652 Toxoplasmosis KEGG
NFKB1 pathway0002653 Amoebiasis KEGG
NFKB1 pathway0002655 Hepatitis C KEGG
NFKB1 pathway0002656 Pathways in cancer KEGG
NFKB1 pathway0002659 Pancreatic cancer KEGG
NFKB1 pathway0002662 Prostate cancer KEGG
NFKB1 pathway0002667 Chronic myeloid leukemia KEGG
NFKB1 pathway0002668 Acute myeloid leukemia KEGG
NFKB1 pathway0002669 Small cell lung cancer KEGG
NFKB1 pathway0002696 Hs_Apoptosis-related_network_due_to_altered_Notch3_in_ovarian_cancer_WP2864_79278 WikiPathways
NFKB1 pathway0002699 Hs_Corticotropin-releasing_hormone_signaling_pathway_WP2355_90017 WikiPathways
NFKB1 pathway0002704 Hs_Factors_and_pathways_affecting_insulin-like_growth_factor_(IGF1)-Akt_signaling_WP3850_88165 WikiPathways
NFKB1 pathway0002712 Hs_Leptin_signaling_pathway_WP2034_89856 WikiPathways
NFKB1 pathway0002731 Hs_Integrated_Breast_Cancer_Pathway_WP1984_82941 WikiPathways
NFKB1 pathway0002734 Hs_Apoptosis_Modulation_and_Signaling_WP1772_91293 WikiPathways
NFKB1 pathway0002754 Hs_Structural_Pathway_of_Interleukin_1_(IL-1)_WP2637_87707 WikiPathways
NFKB1 pathway0002760 Hs_Oncostatin_M_Signaling_Pathway_WP2374_73668 WikiPathways
NFKB1 pathway0002762 Hs_TNF_related_weak_inducer_of_apoptosis_(TWEAK)_Signaling_Pathway_WP2036_89910 WikiPathways
NFKB1 pathway0002769 Hs_Apoptosis_Modulation_by_HSP70_WP384_67054 WikiPathways
NFKB1 pathway0002778 Hs_Glucocorticoid_&_Mineralcorticoid_Metabolism_WP237_78497 WikiPathways
NFKB1 pathway0002779 Hs_Allograft_Rejection_WP2328_90020 WikiPathways
NFKB1 pathway0002780 Hs_Oxidative_Damage_WP3941_90810 WikiPathways
NFKB1 pathway0002784 Hs_T-Cell_Receptor_and_Co-stimulatory_Signaling_WP2583_86147 WikiPathways
NFKB1 pathway0002786 Hs_MicroRNAs_in_cardiomyocyte_hypertrophy_WP1544_89794 WikiPathways
NFKB1 pathway0002801 Hs_TNF_alpha_Signaling_Pathway_WP231_89895 WikiPathways
NFKB1 pathway0002809 Hs_IL17_signaling_pathway_WP2112_89838 WikiPathways
NFKB1 pathway0002811 Hs_Estrogen_signaling_pathway_WP712_78491 WikiPathways
NFKB1 pathway0002825 Hs_Gene_regulatory_network_modelling_somitogenesis_WP2854_87527 WikiPathways
NFKB1 pathway0002845 Hs_TLR4_Signaling_and_Tolerance_WP3851_90114 WikiPathways
NFKB1 pathway0002846 Hs_IL1_and_megakaryocytes_in_obesity_WP2865_88662 WikiPathways
NFKB1 pathway0002855 Hs_NAD_metabolism,_sirtuins_and_aging_WP3630_88178 WikiPathways
NFKB1 pathway0002860 Hs_Prolactin_Signaling_Pathway_WP2037_90015 WikiPathways
NFKB1 pathway0002862 Hs_AGE-RAGE_pathway_WP2324_89798 WikiPathways
NFKB1 pathway0002864 Hs_IL-4_Signaling_Pathway_WP395_89828 WikiPathways
NFKB1 pathway0002865 Hs_Brain-Derived_Neurotrophic_Factor_(BDNF)_signaling_pathway_WP2380_89803 WikiPathways
NFKB1 pathway0002868 Hs_T-Cell_antigen_Receptor_(TCR)_Signaling_Pathway_WP69_89937 WikiPathways
NFKB1 pathway0002870 Hs_IL-1_signaling_pathway_WP195_89932 WikiPathways
NFKB1 pathway0002874 Hs_RANKL-RANK_(Receptor_activator_of_NFKB_(ligand))_Signaling_Pathway_WP2018_90016 WikiPathways
NFKB1 pathway0002877 Hs_B_Cell_Receptor_Signaling_Pathway_WP23_89900 WikiPathways
NFKB2 pathway0000151 Alternative NF-kappaB pathway PID
NFKB2 pathway0000196 Apoptosis signaling pathway PANTHER
NFKB2 pathway0000552 Dectin-1 mediated noncanonical NF-kB signaling Reactome
NFKB2 pathway0000590 DEx/H-box helicases activate type I IFN and inflammatory cytokines production Reactome
NFKB2 pathway0001089 IkBA variant leads to EDA-ID Reactome
NFKB2 pathway0001090 IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) Reactome
NFKB2 pathway0001116 IL12-mediated signaling events PID
NFKB2 pathway0001147 Inflammation mediated by chemokine and cytokine signaling pathway PANTHER
NFKB2 pathway0001182 Interleukin-1 processing Reactome
NFKB2 pathway0001194 Intracellular Signalling Through Adenosine Receptor A2a and Adenosine SMPDB
NFKB2 pathway0001195 Intracellular Signalling Through Adenosine Receptor A2b and Adenosine SMPDB
NFKB2 pathway0001497 NIK-->noncanonical NF-kB signaling Reactome
NFKB2 pathway0001799 RANKL NetPath
NFKB2 pathway0001908 RIP-mediated NFkB activation via ZBP1 Reactome
NFKB2 pathway0002189 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Reactome
NFKB2 pathway0002249 TNFalpha NetPath
NFKB2 pathway0002284 TRAF6 mediated NF-kB activation Reactome
NFKB2 pathway0002355 TSLP NetPath
NFKB2 pathway0002356 TWEAK NetPath
NFKB2 pathway0002562 MAPK signaling pathway KEGG
NFKB2 pathway0002656 Pathways in cancer KEGG
NFKB2 pathway0002801 Hs_TNF_alpha_Signaling_Pathway_WP231_89895 WikiPathways
NKX2-5 pathway0001649 Physiological factors Reactome
NKX2-5 pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
NKX2-5 pathway0002460 YAP1- and WWTR1 (TAZ)-stimulated gene expression Reactome
NKX2-5 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
PAX5 pathway0000335 C-MYB transcription factor network PID
PAX5 pathway0001078 ID NetPath
PITX2 pathway0001848 Regulation of nuclear beta catenin signaling and target gene transcription PID
PITX2 pathway0002591 TGF-beta signaling pathway KEGG
PITX2 pathway0002768 Hs_Heart_Development_WP1591_90186 WikiPathways
PITX2 pathway0002771 Hs_BMP_Signaling_Pathway_in_Eyelid_Development_WP3927_90735 WikiPathways
POLR3A pathway0000532 Cytosolic sensors of pathogen-associated DNA Reactome
POLR3A pathway0001926 RNA Polymerase III Abortive And Retractive Initiation Reactome
POLR3A pathway0001927 RNA Polymerase III Chain Elongation Reactome
POLR3A pathway0001928 RNA Polymerase III Transcription Initiation From Type 1 Promoter Reactome
POLR3A pathway0001929 RNA Polymerase III Transcription Initiation From Type 2 Promoter Reactome
POLR3A pathway0001930 RNA Polymerase III Transcription Initiation From Type 3 Promoter Reactome
POLR3A pathway0001931 RNA Polymerase III Transcription Termination Reactome
POLR3A pathway0002492 Purine metabolism KEGG
POLR3A pathway0002494 Pyrimidine metabolism KEGG
POLR3A pathway0002605 Cytosolic DNA-sensing pathway KEGG
REL pathway0000072 Activation of NF-kappaB in B cells Reactome
REL pathway0000196 Apoptosis signaling pathway PANTHER
REL pathway0000250 Atypical NF-kappaB pathway PID
REL pathway0000270 BCR NetPath
REL pathway0001115 IL1 NetPath
REL pathway0001264 Leptin NetPath
REL pathway0001799 RANKL NetPath
REL pathway0001825 Regulation of Androgen receptor activity PID
REL pathway0002199 TCR NetPath
REL pathway0002249 TNFalpha NetPath
REL pathway0002801 Hs_TNF_alpha_Signaling_Pathway_WP231_89895 WikiPathways
REL pathway0002868 Hs_T-Cell_antigen_Receptor_(TCR)_Signaling_Pathway_WP69_89937 WikiPathways
REL pathway0002870 Hs_IL-1_signaling_pathway_WP195_89932 WikiPathways
REL pathway0002877 Hs_B_Cell_Receptor_Signaling_Pathway_WP23_89900 WikiPathways
SOX4 pathway0000549 Deactivation of the beta-catenin transactivating complex Reactome
SOX4 pathway0001130 IL5 NetPath
SOX9 pathway0000549 Deactivation of the beta-catenin transactivating complex Reactome
SOX9 pathway0002222 TGF_beta_Receptor NetPath
SOX9 pathway0002747 Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways
SOX9 pathway0002791 Hs_Spinal_Cord_Injury_WP2431_87678 WikiPathways
SRF pathway0000492 Coregulation of Androgen receptor activity PID
SRF pathway0000692 ErbB1 downstream signaling PID
SRF pathway0001191 Interleukin signaling pathway PANTHER
SRF pathway0001572 p38 MAPK pathway PANTHER
SRF pathway0001574 p38 signaling mediated by MAPKAP kinases PID
SRF pathway0001604 PDGF signaling pathway PANTHER
SRF pathway0001605 PDGFR-alpha signaling pathway PID
SRF pathway0001606 PDGFR-beta signaling pathway PID
SRF pathway0001805 Ras Pathway PANTHER
SRF pathway0001894 RHO GTPases Activate Formins Reactome
SRF pathway0001903 RhoA signaling pathway PID
SRF pathway0002034 Signaling events mediated by HDAC Class II PID
SRF pathway0002340 Trk receptor signaling mediated by the MAPK pathway PID
SRF pathway0002562 MAPK signaling pathway KEGG
SRF pathway0002743 Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 WikiPathways
SRF pathway0002750 Hs_Serotonin_Receptor_4-6-7_and_NR3C_Signaling_WP734_74438 WikiPathways
SRF pathway0002826 Hs_Mesodermal_Commitment_Pathway_WP2857_87780 WikiPathways
SRF pathway0002834 Hs_Serotonin_Receptor_2_and_ELK-SRF-GATA4_signaling_WP732_80010 WikiPathways
TCF3 pathway0000393 CDO in myogenesis Reactome
TCF3 pathway0001078 ID NetPath
TCF3 pathway0001516 Notch-mediated HES/HEY network PID
TCF3 pathway0001517 Notch NetPath
TCF3 pathway0001574 p38 signaling mediated by MAPKAP kinases PID
TCF3 pathway0001849 Regulation of nuclear SMAD2/3 signaling PID
TCF3 pathway0002439 Wnt NetPath
TCF3 pathway0002841 Hs_Ectoderm_Differentiation_WP2858_89329 WikiPathways
TFAP2A pathway0000377 Caspase Cascade in Apoptosis PID
TFAP2A pathway0002699 Hs_Corticotropin-releasing_hormone_signaling_pathway_WP2355_90017 WikiPathways
TFAP2A pathway0002747 Hs_Neural_Crest_Differentiation_WP2064_79263 WikiPathways
TFAP2A pathway0002841 Hs_Ectoderm_Differentiation_WP2858_89329 WikiPathways
TFAP2A pathway0002849 Hs_Hypothetical_Craniofacial_Development_Pathway_WP3655_88473 WikiPathways
TFAP2C pathway0002394 Validated transcriptional targets of TAp63 isoforms PID
ZNF263 pathway0000905 Generic Transcription Pathway Reactome