About Enhancer

Enhancer ID: E_02_312
Enhancer symbol: --
Species: Mouse
Position : chr11:100859351-100885169
Biosample name: Mammary Epithelium
Experiment class : Low+High throughput
Enhancer type: Enhancer
Disease: --
DO: --
Mesh: --
Distance from TSS: --
Pubmed ID:  26446995
Enhancer experiment: PCR,ChIP-seq,RT-PCR,DNase-seq
Enhancer experiment description: MED1 binding coincided with STAT5 occupancy. RNA Pol II binding also coincided with these sequences.

About Target gene

Target gene : Stat5
Strong evidence: --
Less strong evidence: PCR,ChIP-seq,RT-PCR,DNase-seq
Target gene experiment description: MED1 binding coincided with STAT5 occupancy. RNA Pol II binding also coincided with these sequences.

About TF

TF name : --
TF experiment: --
TF experiment description: --

About Function

Enhancer function : Transcriptome analysis identified a class of mammary-restricted genes that was particularly dependent on high STAT5 levels as a result of the intergenic enhancer.
Enhancer function experiment: CRISPR/Cas9
Enhancer function
experiment description:
Taken together, the mammary_x0002_specific enhancer enables a positive feedback cir_x0002_cuit that contributes to the remarkable abundance of STAT5 and, in turn, to the efficacy of STAT5-dependent mammary physiology.

About SNP

SNP ID: --
SNP position: --
SNP experiment: --

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs