About Enhancer
| Enhancer ID: | E_02_250 | |
| Enhancer symbol: | Gata3 distal Enhancers | |
| Species: | Mouse | |
| Position : | chr2:9838078-9840078   |
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| Biosample name: | Mouse Embryos | |
| Experiment class : | Low throughput |
| Enhancer type: | Enhancer | |
| Disease: | -- | |
| DO: | -- | |
| Mesh: | -- | |
| Distance from TSS: | >2KB | |
| Pubmed ID: | 30295986 |
| Enhancer experiment: | Luciferase Reporter Assay,qPCR | |
| Enhancer experiment description: | We next employed a transient transfection assay to test putative Gata3 Enhancers in Gata3-expressing 293T cells using a heterologous TATA promoter that drives Luciferasegene expression. Here we describe the identification of a novel bipartite Gata3 lens-specific Enhancer located ~18 kb upstream from its transcriptional start site. We also found that a 5 kb Gata3 promoter possesses low activity in the lens. |
About Target gene
| Target gene : | Gata3(Gata-3,jal) | |
| Strong evidence: | -- | |
| Less strong evidence: | Luciferase Reporter Assay,qPCR | |
| Target gene experiment description: | Here we describe the identification of a novel bipartite Gata3 lens-specific enhancer located 18 kb upstream from its transcriptional start site. We also found that a 5-kb Gata3 promoter possesses low activity in the lens. The bipartite enhancer contains arrays of AP-1, Ets-, and Smad1/5-binding sites as well as binding sites for lensassociated DNA-binding factors. |
About TF
| TF name : | -- | |
| TF experiment: | -- | |
| TF experiment description: | -- |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- | |
| SNP position: | -- |
| SNP experiment: | -- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
