About Enhancer
| Enhancer ID: | E_02_138 | |
| Enhancer symbol: | -- | |
| Species: | Mouse | |
| Position : | chr17:31794375-31829875   |
|
| Biosample name: | Embryonic Stem Cell | |
| Experiment class : | Low throughput |
| Enhancer type: | Super-Enhancer | |
| Disease: | -- | |
| DO: | -- | |
| Mesh: | -- | |
| Distance from TSS: | >2KB | |
| Pubmed ID: | 25801169 |
| Enhancer experiment: | Luciferase Reporter Assay | |
| Enhancer experiment description: | The five super-enhancers show physical interactions with their respective associated genes and are located within insulated neighborhoods in the ESC genome , suggesting that these genes represent the bona fide physiological targets of the five SEs. |
About Target gene
| Target gene : | Sik1(Hrt-20,Msk,Sik,Sik-1,Snf1lk) | |
| Strong evidence: | CRISPR/Cas9 | |
| Less strong evidence: | -- | |
| Target gene experiment description: | These five super-enhancers control transcription of Prdm14, miR-290-295, Sik1, Klf2 and Pou5f1 (Oct5), which play important roles in ESC self-renewal, pluripotency and differentiation. |
About TF
| TF name : | -- | |
| TF experiment: | -- | |
| TF experiment description: | -- |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- | |
| SNP position: | -- |
| SNP experiment: | -- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
