About Enhancer
Enhancer ID: |
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E_02_131 |
Enhancer symbol: |
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Grhl3 Enhancer |
Species: |
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Mouse |
Position : |
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chr4:135548688-135550688
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Biosample name: |
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NMuMG |
Experiment class : |
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Low throughput |
Enhancer type: |
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Enhancer |
Disease: |
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-- |
DO: |
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-- |
Mesh: |
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-- |
Distance from TSS: |
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>2KB |
Pubmed ID: |
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25652130 |
Enhancer experiment: |
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Luciferase Reporter Assay,3C |
Enhancer experiment description: |
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We reported previously that intron 2 of Cdh1 is essential for proper E-cad expression.In order to analyze this large DNA sequence(>40 kb) for putative enhancers we focused on evolutionary conserved sequences. |
About Target gene
Target gene : |
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Grhl3(SOM,TFCP2L4,VWS2) |
Strong evidence: |
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3C |
Less strong evidence: |
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ChIP,qPCR |
Target gene experiment description: |
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Weshow thatCdh1 activity during MET isgovernedby 33 two Enhancers at +7.8 and at +11.5 within intron 2 that are activated by binding of Grhl3 and Hnf4α, 34 respectively. |
About TF
TF name : |
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-- |
TF experiment: |
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-- |
TF experiment description: |
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-- |
About Function
Enhancer function : |
-- |
Enhancer function experiment: |
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Enhancer function experiment description: |
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About SNP
SNP ID: |
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-- |
SNP position: |
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-- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
Expression of target genes for the enhancer
Enhancer associated SNPs