About Enhancer

Enhancer ID: E_02_123
Enhancer symbol: E8VI Enhancer
Species: Mouse
Position : chr6:71341692-71345212
Biosample name: CD4+ T Cell
Experiment class : Low throughput
Enhancer type: Enhancer
Disease: --
DO: --
Mesh: --
Distance from TSS: >2KB
Pubmed ID:  25548254
Enhancer experiment: ChIP,PCR
Enhancer experiment description: Strikingly, 6 ECRs (ECR-2, -3, -6, -7, -8, and -10) overlapped with previously identified Cd8 enhancers. This indicated a good correlation between the location of already described Cd8 cis-regulatory elements and the presence of ECRs.

About Target gene

Target gene : Cd8a(BB154331,Ly-2,Ly-35,Ly-B,Lyt-2),Cd8b1(Cd8b,Ly-3,Ly-C,Lyt-3)
Strong evidence: --
Less strong evidence: Transgenic mice,PCR,ChIP
Target gene experiment description: ChIP assays revealed that E8VI was bound by Runx/CBFb complexes and Bcl11b,and the analysis of Runx3-null CD8+T cell showed that E8VI activity was,in part,dependent on Runx3.

About TF

TF name : Bcl11b(9130430L19Rik,AI604821,B630002E05Rik,BCL-11B,Ctip2,Rit1)
TF experiment: ChIP
TF experiment description: ChIP assays revealed that E8VI was bound by Runx/CBFb complexes and Bcl11b,and the analysis of Runx3-null CD8+T cell showed that E8VI activity was,in part,dependent on Runx3.

About Function

Enhancer function : --
Enhancer function experiment: --
Enhancer function
experiment description:
--

About SNP

SNP ID: --
SNP position: --
SNP experiment: --

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs