Enhancer ID: | E_02_123 | |
Enhancer symbol: | E8VI Enhancer | |
Species: | Mouse | |
Position : | chr6:71341692-71345212 |
|
Biosample name: | CD4+ T Cell | |
Experiment class : | Low throughput |
Enhancer type: | Enhancer | |
Disease: | -- | |
DO: | -- | |
Mesh: | -- | |
Distance from TSS: | >2KB | |
Pubmed ID: | 25548254 |
Enhancer experiment: | ChIP,PCR | |
Enhancer experiment description: | Strikingly, 6 ECRs (ECR-2, -3, -6, -7, -8, and -10) overlapped with previously identified Cd8 enhancers. This indicated a good correlation between the location of already described Cd8 cis-regulatory elements and the presence of ECRs. |
Target gene : | Cd8a(BB154331,Ly-2,Ly-35,Ly-B,Lyt-2),Cd8b1(Cd8b,Ly-3,Ly-C,Lyt-3) | |
Strong evidence: | -- | |
Less strong evidence: | Transgenic mice,PCR,ChIP | |
Target gene experiment description: | ChIP assays revealed that E8VI was bound by Runx/CBFb complexes and Bcl11b,and the analysis of Runx3-null CD8+T cell showed that E8VI activity was,in part,dependent on Runx3. |
TF name : | Bcl11b(9130430L19Rik,AI604821,B630002E05Rik,BCL-11B,Ctip2,Rit1) | |
TF experiment: | ChIP | |
TF experiment description: | ChIP assays revealed that E8VI was bound by Runx/CBFb complexes and Bcl11b,and the analysis of Runx3-null CD8+T cell showed that E8VI activity was,in part,dependent on Runx3. |
Enhancer function : | -- |
Enhancer function experiment: | -- |
Enhancer function experiment description: |
-- |
SNP ID: | -- | |
SNP position: | -- |
SNP experiment: | -- |
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