Enhancer ID: | E_02_113 | |
Enhancer symbol: | -- | |
Species: | Mouse | |
Position : | chr7:53527011-53528648 |
|
Biosample name: | C2C12 | |
Experiment class : | Low throughput |
Enhancer type: | Enhancer | |
Disease: | -- | |
DO: | -- | |
Mesh: | -- | |
Distance from TSS: | >2KB | |
Pubmed ID: | 25403490 |
Enhancer experiment: | ChIP,PCR | |
Enhancer experiment description: | To gain insight into the mechanism by which MUNC facilitates muscle differentiation, we examined by ChIP the binding of MyoD and myogenin to the regulatory sites known to bind the two transcription factors, the core enhancer region (CER) at -20kb relative to MyoD TSS and theDRR (at -5kb relative to MyoD TSS), and to the sites in the -0.5kb region of the Myogenin promoter |
Target gene : | Myod(AI503393,MYF3,MyoD,Myod-1,bHLHc1) | |
Strong evidence: | -- | |
Less strong evidence: | Western blot,qRT-PCR,Immunofluorescence | |
Target gene experiment description: | RNAs 2 and 3 were of particular interest be_x0002_cause they were located upstream of the TSS of MyoD,a master regulator of skeletal muscle differentiation (12),with ncRNA 2 overlapping a previously known MyoD Enhancer element,known as the distal regulatory region (DRR). |
TF name : | Myod1(AI503393,MYF3,MyoD,Myod-1,bHLHc1) | |
TF experiment: | ChIP | |
TF experiment description: | To gain insight into the mechanism by which MUNC facilitates muscle differentiation,we examined by ChIP the binding of MyoD and myogenin to the regulatory sites known to bind the two transcription factors,the core en_x0002_hancer region (CER) at kb _x0006_20 relative to MyoD TSS and the DRR,(at kb _x0006_5 relative to MyoD TSS),and to the sites in the kb _x0006_0.5 region of the Myogenin promoter. |
Enhancer function : | -- |
Enhancer function experiment: | -- |
Enhancer function experiment description: |
-- |
SNP ID: | -- | |
SNP position: | -- |
SNP experiment: | -- |
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