About Enhancer
| Enhancer ID: | E_02_054 | |
| Enhancer symbol: | -- | |
| Species: | Mouse | |
| Position : | chr1:60908875-60908895   |
|
| Biosample name: | T Cell | |
| Experiment class : | Low throughput |
| Enhancer type: | Enhancer | |
| Disease: | -- | |
| DO: | -- | |
| Mesh: | -- | |
| Distance from TSS: | <2KB | |
| Pubmed ID: | 23024062 |
| Enhancer experiment: | Luciferase Reporter Assay | |
| Enhancer experiment description: | T cells were stimulated with CPT after transfection of CTLA4 luciferase reporter constructs (including -1221, -343, -238, -167, and-63 bp relative to the CTLA4 transcription start site). suggesting the presence of an enhancer binding site in this region. |
About Target gene
| Target gene : | Ctla4(Cd152,Ctla-4,Ly-56) | |
| Strong evidence: | -- | |
| Less strong evidence: | ChIP | |
| Target gene experiment description: | The promoter region from 2150 to 2130 bp contains a putative CREB binding site, a well known downstream transcription factor of cAMP signaling. To define whether the putative CREB binding site (2150 to 2143 bp) is responsive to cAMP, we performed ChIP assay with CREB antibody in T cells, with or without CPT treatment. |
About TF
| TF name : | Creb1(2310001E10Rik,3526402H21Rik,AV083133,Creb,Creb-1) | |
| TF experiment: | ChIP | |
| TF experiment description: | The promoter region from -150 to -130 bp contains a putative CREB binding site, a well known downstream transcription factor of cAMP signaling. |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- | |
| SNP position: | -- |
| SNP experiment: | -- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
