Enhancer ID: | E_02_042 | |
Enhancer symbol: | E3' Enhancer | |
Species: | Mouse | |
Position : | chr6:70735256-70736064 |
|
Biosample name: | S194,MPC-11 | |
Experiment class : | Low throughput |
Enhancer type: | Enhancer | |
Disease: | -- | |
DO: | -- | |
Mesh: | -- | |
Distance from TSS: | >2KB | |
Pubmed ID: | 22323542 |
Enhancer experiment: | DNaseI-seq,Luciferase Reporter Assay,PCR | |
Enhancer experiment description: | We identified a DNA sequence that exhibited B cell-specific, longrange interactions with Ei and E39 using chromosome conformation-capture technology.Mapping and sequence analysis of DNase I-hypersensitive site HS10.To determine whether HS10 corresponded to a new transcriptional enhancer in the locus, we performed transient-transfection assays with a luciferase reporter gene containing a Vk gene promoter (Fig. 2A, construct 1). |
Target gene : | Igk(kappa) | |
Strong evidence: | -- | |
Less strong evidence: | RT-PCR | |
Target gene experiment description: | Finally,to confirm the above results we performed real-timePCR assays to quantitate Igk gene transcript levels in plasma cell populations before and 5 d after immunization. |
TF name : | -- | |
TF experiment: | -- | |
TF experiment description: | -- |
Enhancer function : | -- |
Enhancer function experiment: | -- |
Enhancer function experiment description: |
-- |
SNP ID: | -- | |
SNP position: | -- |
SNP experiment: | -- |
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