About Enhancer

Enhancer ID: E_02_035
Enhancer symbol: --
Species: Mouse
Position : chr11:32249976-32252156
Biosample name: Primary Erythroid Cell
Experiment class : Low+High throughput
Enhancer type: Enhancer
Disease: --
DO: --
Mesh: --
Distance from TSS: >2KB
Pubmed ID:  22264824
Enhancer experiment: RT-PCR,ChIP,ChIP-seq
Enhancer experiment description: Beyond this AFE the isoform structure appears identical to the full-length transcript. Interestingly, the AFE coincides with one of the known intragenic enhancers.First, we tested wild-type mouse tissues by RT-PCR to verify the existence of this alternative transcript.

About Target gene

Target gene : Nprl3(Aag,CGTHBA,HS-26,HS-40,Mare,Phg,Prox1,m(alpha)RE)
Strong evidence: --
Less strong evidence: RT-PCR,ChIP,ChIP-seq
Target gene experiment description: Beyond this AFE the isoform structure appears identical to the full-length transcript. Interestingly, the AFE coincides with one of the known intragenic enhancers.First, we tested wild-type mouse tissues by RT-PCR to verify the existence of this alternative transcript.

About TF

TF name : --
TF experiment: --
TF experiment description: --

About Function

Enhancer function : Intragenic Enhancers frequently act as alternative tissue_x005f_x0002_specific promoters producing a class of abundant,spliced, multiexonic poly(A)+ RNAs (meRNAs) which reflect the host gene’s structure.
Enhancer function experiment: ChIP,RT-PCR,ChIP-seq
Enhancer function
experiment description:
To address this problem, we analyzed transcrip_x005f_x0002_tion of the Nprl3 gene after deleting its constitutive promoter. This revealed that intragenic Enhancers act as highly active, alternative tissue-specific promoters for the gene containing them.

About SNP

SNP ID: --
SNP position: --
SNP experiment: --

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs