About Enhancer
| Enhancer ID: |
|
E_01_261 |
| Enhancer symbol: |
|
YY1 Enhancer |
| Species: |
|
Human |
| Position : |
|
chr12:109986000-109986710
   |
| Biosample name: |
|
WT Mouse Embryonic Fibroblasts |
| Experiment class : |
|
Low+High throughput |
| Enhancer type: |
|
Enhancer |
| Disease: |
|
-- |
| DO: |
|
-- |
| Mesh: |
|
-- |
| Distance from TSS: |
|
>2KB |
| Pubmed ID: |
|
28086087 |
| Enhancer experiment: |
|
ChIP-seq,ChIP-seq,RT-qPCR |
| Enhancer experiment description: |
|
Our data demonstrate that CBP binds to RNAs transcribed close to CBP binding sites such as at the YY1 Enhancer (Figure 6A);recruitment of CBP to active Enhancers results in binding to eRNAs, and that eRNA binding to the HAT domain of CBP stimulates its acetyltransferase activity
|
About Target gene
| Target gene : |
|
YY1(DELTA,GADEVS,INO80S,NF-E1,UCRBP,YIN-YANG-1) |
| Strong evidence: |
|
-- |
| Less strong evidence: |
|
EMSA,ChIP,RT-qPCR |
| Target gene experiment description: |
|
Our data demonstrate that CBP binds to RNAs transcribed close to CBP binding sites such as at the YY1 Enhancer (Figure 6A);recruitment of CBP to active Enhancers results in binding to eRNAs, and that eRNA binding to the HAT domain of CBP stimulates its acetyltransferase activity
|
About TF
| TF name : |
|
-- |
| TF experiment: |
|
-- |
| TF experiment description: |
|
-- |
About Function
| Enhancer function : |
By interacting directly with CBP, eRNAs contribute to the unique chromatin structure at active enhancers, which in turn is required for regulation of target genes. |
| Enhancer function experiment: |
ChIP |
Enhancer function
experiment description: |
By interacting directly with CBP, eRNAs contribute to the unique chromatin structure at active Enhancers, which in turn is required for regulation of target genes. |
About SNP
| SNP ID: |
|
-- |
| SNP position: |
|
-- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
Expression of target genes for the enhancer
Enhancer associated SNPs
