About Enhancer
Enhancer ID: |
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E_01_237 |
Enhancer symbol: |
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-- |
Species: |
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Human |
Position : |
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chr7:117282955-117335227
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Biosample name: |
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Human Nasal Epithelial Cell,Skin Fibroblasts Cell |
Experiment class : |
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Low+High throughput |
Enhancer type: |
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Enhancer |
Disease: |
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Epithelial Cancer |
DO: |
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Mesh: |
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Distance from TSS: |
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>2KB |
Pubmed ID: |
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26615198 |
Enhancer experiment: |
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Hi-C,5C,Luciferase Reporter Assay,PCR |
Enhancer experiment description: |
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We tested whether any of the newly identiied looping regions displayed enhancer activity in a reporter assay. As shown in Figure 4A, two of our interacting regions significantly enhanced CFTR promoter activity.The fragment encompassing a DHS in the region E displayed a strong Enhancer function with almost 6-fold effect on the CFTR promoter. |
About Target gene
Target gene : |
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CFTR(ABC35,ABCC7,CF/MRP,MRP7,TNR-CFTR,dJ760C5.1\) |
Strong evidence: |
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-- |
Less strong evidence: |
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Luciferase Reporter Assay |
Target gene experiment description: |
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As shown in Figure 4A, two of our interacting regions significantly enhanced CFTR promoter activity. The G region containing a DHS and a CTCF binding site also acted as an Enhancer. |
About TF
TF name : |
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TF experiment: |
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TF experiment description: |
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About Function
Enhancer function : |
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Enhancer function experiment: |
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Enhancer function experiment description: |
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About SNP
SNP ID: |
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-- |
SNP position: |
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Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
Expression of target genes for the enhancer
Enhancer associated SNPs