About Enhancer

Enhancer ID: E_01_237
Enhancer symbol: --
Species: Human
Position : chr7:117282955-117335227
Biosample name: Human Nasal Epithelial Cell,Skin Fibroblasts Cell
Experiment class : Low+High throughput
Enhancer type: Enhancer
Disease: Epithelial Cancer
DO: --
Mesh: --
Distance from TSS: >2KB
Pubmed ID:  26615198
Enhancer experiment: Hi-C,5C,Luciferase Reporter Assay,PCR
Enhancer experiment description: We tested whether any of the newly identiied looping regions displayed enhancer activity in a reporter assay. As shown in Figure 4A, two of our interacting regions significantly enhanced CFTR promoter activity.The fragment encompassing a DHS in the region E displayed a strong Enhancer function with almost 6-fold effect on the CFTR promoter.

About Target gene

Target gene : CFTR(ABC35,ABCC7,CF/MRP,MRP7,TNR-CFTR,dJ760C5.1\)
Strong evidence: --
Less strong evidence: Luciferase Reporter Assay
Target gene experiment description: As shown in Figure 4A, two of our interacting regions significantly enhanced CFTR promoter activity. The G region containing a DHS and a CTCF binding site also acted as an Enhancer.

About TF

TF name : --
TF experiment: --
TF experiment description: --

About Function

Enhancer function : --
Enhancer function experiment: --
Enhancer function
experiment description:
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About SNP

SNP ID: --
SNP position: --
SNP experiment: --

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs