About Enhancer
| Enhancer ID: | E_01_235 | |
| Enhancer symbol: | -- | |
| Species: | Human | |
| Position : | chr11:118540532-118575295   |
|
| Biosample name: | Normal Human Astrocyte | |
| Experiment class : | Low throughput |
| Enhancer type: | Enhancer | |
| Disease: | Glioma | |
| DO: | DOID:3070 | |
| Mesh: | D005910 | |
| Distance from TSS: | >2KB | |
| Pubmed ID: | 26610392 |
| Enhancer experiment: | Luciferase Reporter Assay,3C | |
| Enhancer experiment description: | After testing candidate SNPs for allele-specific activity in a luciferase-based enhancer scanning assay, we established a subset of 10 functional SNPs in the promoters of PHLDB1 and DDX6, and in a putative enhancer element. Chromatin conformation capture (3C) identified a physical interaction between the enhancer element containing a functional SNP (rs73001406) and the promoter of the DDX6 gene. |
About Target gene
| Target gene : | DDX6(HLR2,P54,RCK) | |
| Strong evidence: | 3C | |
| Less strong evidence: | Luciferase Reporter Assay | |
| Target gene experiment description: | After testing candidate SNPs for allele-specific activity in a luciferase-based enhancer scanning assay, we established a subset of 10 functional SNPs in the promoters of PHLDB1 and DDX6, and in a putative enhancer element. Chromatin conformation capture (3C) identified a physical interaction between the enhancer element containing a functional SNP (rs73001406) and the promoter of the DDX6 gene. |
About TF
| TF name : | -- | |
| TF experiment: | -- | |
| TF experiment description: | -- |
About Function
| Enhancer function : | -- |
| Enhancer function experiment: | -- |
| Enhancer function experiment description: |
-- |
About SNP
| SNP ID: | -- | |
| SNP position: | -- |
| SNP experiment: | -- |
Enhancer associated network
The number on yellow line represents the distance between enhancer and target gene
