About Enhancer

Enhancer ID: E_01_224
Enhancer symbol: --
Species: Human
Position : chr6:1614188-1617051
Biosample name: Embryonic Stem Cell
Experiment class : Low+High throughput
Enhancer type: Enhancer
Disease: --
DO: --
Mesh: --
Distance from TSS: >2KB
Pubmed ID:  26382291
Enhancer experiment: Enhancer Assay
Enhancer experiment description: We experimentally validate four novel Enhancers in this locus and demonstrate that these Enhancers show consistent activity during embryonic development in domains that overlap with the expression of FOXC1 and GMDS.

About Target gene

Target gene : FOXC1(ARA,ASGD3,FKHL7,FREAC-3,FREAC3,IGDA,IHG1,IRID1,RIEG3),GMDS(GMD,SDR3E1)
Strong evidence: --
Less strong evidence: Enhancer Assay
Target gene experiment description: We experimentally validate four novel Enhancers in this locus and demonstrate that these Enhancers show consistent activity during embryonic development in domains that overlap with the expression of FOXC1 and GMDS.

About TF

TF name : ZIC1(CRS6,ZIC,ZNF201)
TF experiment: X-Gal Staining Assay
TF experiment description: An image from the UCSC Genome Browser showing the enhancer landscape near FOXC1 and GMDS.The lower panel is zoomed in to the regions immediately surrounding the enhancers, to highlight the ZIC1 binding sites. b E11.5 whole-mount images of ZIC mutants CE1–3. CE4 only yielded two X gal- positive embryos and was thus not used in the analysis. Tissues that have lacZ expression in at least half of the X-gal-positive embryos in WT but not in ZIC enhancers are noted in red. Arrowheads mark regions of interest.

About Function

Enhancer function : --
Enhancer function experiment: --
Enhancer function
experiment description:
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About SNP

SNP ID: --
SNP position: --
SNP experiment: --

Enhancer associated network

The number on yellow line represents the distance between enhancer and target gene

Expression of target genes for the enhancer


Enhancer associated SNPs