Enhancer ID: | E_01_103 | |
Enhancer symbol: | -- | |
Species: | Human | |
Position : | chr14:90847327-90849327 |
|
Biosample name: | MCF-7,K-562,HeLa,HCT 116,Nb4 | |
Experiment class : | Low+High throughput |
Enhancer type: | Enhancer | |
Disease: | Congenital Limb Deformity | |
DO: | -- | |
Mesh: | D017880 | |
Distance from TSS: | >2KB | |
Pubmed ID: | 22265404 |
Enhancer experiment: | 3C-qPCR,Luciferase Reporter Assay,ChIP-seq | |
Enhancer experiment description: | To examine potential enhancer activity of promoters, we per_x0002_formed luciferase reporter gene assays, a commonly used method for promoter and enhancer characterization. |
Target gene : | CALM1 (CALML2,CAM2,CAM3,CAMB,CAMC,CAMI,CAMIII,CPVT4,DD132,LQT14,PHKD,caM) | |
Strong evidence: | 3C-qPCR | |
Less strong evidence: | Luciferase Reporter Assay | |
Target gene experiment description: | In another example (Figure 5F), the promoter of CALM1 interacts with an enhancer element 15 kb upstream and connects to the promoter of C14orf102 further upstream in 65kb. Both RNA-Seq data and the H3K4me3/me1 log ratio indi_x0002_cated that the CALM1 promoter was strong, whereas the C14orf102 promoter was weak and enhancer-like. The luciferase reporter gene assay showed marginal enhancement to the CALM1 promoter reporter gene activity by the native CALM1 enhancer and the C14orf102 promoter individually. |
TF name : | -- | |
TF experiment: | -- | |
TF experiment description: | -- |
Enhancer function : | -- |
Enhancer function experiment: | -- |
Enhancer function experiment description: |
-- |
SNP ID: | -- | |
SNP position: | -- |
SNP experiment: | -- |
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